Experiment set1IT045 for Pseudomonas fluorescens FW300-N1B4

Compare to:

LB with copper (II) chloride dihydrate 2.5 mM

200 most detrimental genes:

  gene name fitness t score description  
Pf1N1B4_2380 +3.0 19.0 Cytochrome B561 compare
Pf1N1B4_2381 +2.8 18.2 Protein yceI precursor compare
Pf1N1B4_5925 +1.9 12.5 hypothetical protein compare
Pf1N1B4_5926 +1.9 12.0 hypothetical protein compare
Pf1N1B4_2060 +1.3 3.1 hypothetical protein compare
Pf1N1B4_5331 +1.2 3.2 hypothetical protein compare
Pf1N1B4_5357 +1.1 2.4 hypothetical protein compare
Pf1N1B4_5924 +1.1 5.0 hypothetical protein compare
Pf1N1B4_4358 +1.1 2.5 Acetyltransferase, GNAT family compare
Pf1N1B4_2750 +1.1 2.0 3-dehydroquinate dehydratase II (EC 4.2.1.10) compare
Pf1N1B4_399 +1.0 2.7 2-dehydro-3-deoxyphosphogalactonate aldolase (EC 4.1.2.21) compare
Pf1N1B4_3141 +1.0 1.6 FIG00959768: hypothetical protein compare
Pf1N1B4_967 +1.0 2.4 hypothetical protein compare
Pf1N1B4_2421 +1.0 2.3 L-proline glycine betaine ABC transport system permease protein ProW (TC 3.A.1.12.1) compare
Pf1N1B4_3468 +0.9 2.4 Negative regulator of flagellin synthesis FlgM compare
Pf1N1B4_2975 +0.9 2.1 Peptide methionine sulfoxide reductase MsrB (EC 1.8.4.12) compare
Pf1N1B4_2244 +0.9 2.7 Taurine-binding periplasmic protein TauA compare
Pf1N1B4_3368 +0.9 2.3 Allophanate hydrolase 2 subunit 2 (EC 3.5.1.54) compare
Pf1N1B4_1967 +0.9 3.0 hypothetical protein compare
Pf1N1B4_4438 +0.9 2.2 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) compare
Pf1N1B4_4980 +0.9 2.3 putative lipoprotein compare
Pf1N1B4_1485 +0.9 2.3 FIG00963848: hypothetical protein compare
Pf1N1B4_3794 +0.9 2.4 hypothetical protein compare
Pf1N1B4_5105 +0.8 2.5 Peptide ABC transporter, ATP-binding protein compare
Pf1N1B4_3038 +0.8 2.3 Chemotaxis response regulator protein-glutamate methylesterase CheB (EC 3.1.1.61) compare
Pf1N1B4_124 +0.8 1.9 Mechanosensitive ion channel compare
Pf1N1B4_4107 +0.8 1.8 Probable glutathione S-transferase (EC 2.5.1.18), YfcF homolog compare
Pf1N1B4_1963 +0.8 3.6 O-antigen export system permease protein RfbD compare
Pf1N1B4_2029 +0.8 2.5 FIG00953722: hypothetical protein compare
Pf1N1B4_81 +0.8 2.2 Putative sulfate permease compare
Pf1N1B4_2273 +0.8 3.4 hypothetical protein compare
Pf1N1B4_883 +0.8 1.4 Hypothetical nudix hydrolase YeaB compare
Pf1N1B4_6045 +0.8 1.8 CigR (Putative inner membrane protein) compare
Pf1N1B4_4181 +0.8 1.8 FIG00957123: hypothetical protein compare
Pf1N1B4_2269 +0.8 1.6 Purine nucleoside phosphorylase (EC 2.4.2.1) compare
Pf1N1B4_2858 +0.8 5.8 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf1N1B4_3660 +0.8 3.4 Hydroxypyruvate isomerase (EC 5.3.1.22) compare
Pf1N1B4_758 +0.7 2.1 Bacterioferritin compare
Pf1N1B4_115 +0.7 1.4 Membrane protein mosC compare
Pf1N1B4_3372 +0.7 1.6 FIG00962464: hypothetical protein compare
Pf1N1B4_2287 +0.7 3.4 Protein of unknown function DUF81 compare
Pf1N1B4_3439 +0.7 2.4 hypothetical protein compare
Pf1N1B4_118 +0.7 2.1 Sigma-70 factor FpvI (ECF subfamily), controling pyoverdin biosynthesis @ FIG006045: Sigma factor, ECF subfamily compare
Pf1N1B4_2435 +0.7 2.6 hypothetical protein compare
Pf1N1B4_2640 +0.7 2.9 FIG003461: hypothetical protein compare
Pf1N1B4_101 +0.7 1.8 hypothetical protein compare
Pf1N1B4_2733 +0.7 1.8 DNA polymerase III alpha subunit (EC 2.7.7.7) compare
Pf1N1B4_4799 +0.7 1.6 Multidrug resistance protein B compare
Pf1N1B4_3098 +0.7 2.4 Ribonuclease HII (EC 3.1.26.4) compare
Pf1N1B4_4455 +0.7 1.6 FIG00953528: hypothetical protein compare
Pf1N1B4_3485 +0.7 1.7 hypothetical protein compare
Pf1N1B4_3074 +0.7 1.7 HesA/MoeB/ThiF family protein related to EC-YgdL compare
Pf1N1B4_2776 +0.7 2.2 Transcriptional regulator, GntR family compare
Pf1N1B4_72 +0.7 1.1 Transcriptional regulator, LysR family compare
Pf1N1B4_255 +0.7 2.4 Free methionine-(R)-sulfoxide reductase, contains GAF domain compare
Pf1N1B4_4692 +0.7 2.2 hypothetical protein compare
Pf1N1B4_4394 +0.7 2.4 FIG00955080: hypothetical protein compare
Pf1N1B4_3492 +0.7 2.2 DNA-3-methyladenine glycosylase (EC 3.2.2.20) compare
Pf1N1B4_5296 +0.7 3.7 hypothetical protein compare
Pf1N1B4_761 +0.7 1.8 FIG00954879: hypothetical protein compare
Pf1N1B4_3907 +0.7 2.0 FIG00953287: hypothetical protein compare
Pf1N1B4_5508 +0.7 1.7 hypothetical protein compare
Pf1N1B4_5574 +0.7 1.9 hypothetical protein compare
Pf1N1B4_5860 +0.7 1.7 Two-component response regulator compare
Pf1N1B4_2182 +0.7 3.3 Glutathione S-transferase N-terminal domain protein (EC 2.5.1.18) compare
Pf1N1B4_308 +0.7 2.5 FIG00956090: hypothetical protein compare
Pf1N1B4_5022 +0.7 1.8 hypothetical protein compare
Pf1N1B4_4089 +0.7 1.8 hypothetical protein compare
Pf1N1B4_474 +0.7 3.0 FIG00954461: hypothetical protein compare
Pf1N1B4_2731 +0.7 1.9 Uncharacterized protein conserved in bacteria compare
Pf1N1B4_349 +0.7 2.3 Biosynthetic Aromatic amino acid aminotransferase beta (EC 2.6.1.57) compare
Pf1N1B4_1338 +0.7 3.3 Uncharacterized iron-regulated membrane protein; Iron-uptake factor PiuB compare
Pf1N1B4_3125 +0.7 2.6 FIG00954242: hypothetical protein compare
Pf1N1B4_263 +0.7 1.3 Thiopurine S-methyltransferase (EC 2.1.1.67) compare
Pf1N1B4_4636 +0.7 1.5 TPR domain protein in aerotolerance operon compare
Pf1N1B4_3020 +0.7 2.8 Single-stranded-DNA-specific exonuclease RecJ (EC 3.1.-.-) compare
Pf1N1B4_3991 +0.6 1.2 Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family compare
Pf1N1B4_4470 +0.6 1.9 Cobalt-zinc-cadmium resistance protein CzcD compare
Pf1N1B4_5884 +0.6 1.6 UDP-glucose dehydrogenase (EC 1.1.1.22) compare
Pf1N1B4_102 +0.6 1.0 Methyl-accepting chemotaxis protein I (serine chemoreceptor protein) compare
Pf1N1B4_4445 +0.6 1.7 acetyltransferase, GNAT family compare
Pf1N1B4_1756 +0.6 1.7 Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases compare
Pf1N1B4_1424 +0.6 2.1 hypothetical protein compare
Pf1N1B4_4879 +0.6 1.4 Chromosome segregation ATPases compare
Pf1N1B4_4220 +0.6 1.8 Maebl compare
Pf1N1B4_2240 +0.6 1.9 Transcriptional regulator, AsnC family compare
Pf1N1B4_2794 +0.6 1.7 FIG00953595: hypothetical protein compare
Pf1N1B4_4376 +0.6 2.0 probable transmembrane protein compare
Pf1N1B4_3787 +0.6 2.1 FIG00960829: hypothetical protein compare
Pf1N1B4_4556 +0.6 1.5 D-beta-hydroxybutyrate dehydrogenase (EC 1.1.1.30) compare
Pf1N1B4_4648 +0.6 1.7 transcriptional regulator, MerR family compare
Pf1N1B4_1632 +0.6 2.8 FIG001341: Probable Fe(2+)-trafficking protein YggX compare
Pf1N1B4_483 +0.6 1.4 Metal-dependent hydrolase related to alanyl-tRNA synthetase compare
Pf1N1B4_2314 +0.6 1.5 FIG028932: hypothetical protein compare
Pf1N1B4_4194 +0.6 2.0 2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34) compare
Pf1N1B4_34 +0.6 0.7 Xanthine permease compare
Pf1N1B4_825 +0.6 1.2 tRNA (uridine-5-oxyacetic acid methyl ester) 34 synthase compare
Pf1N1B4_885 +0.6 1.7 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf1N1B4_4837 +0.6 1.4 hypothetical protein compare
Pf1N1B4_4257 +0.6 1.1 L-serine dehydratase, (PLP)-dependent (EC 4.3.1.17) @ Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf1N1B4_38 +0.6 2.3 Exodeoxyribonuclease III (EC 3.1.11.2) compare
Pf1N1B4_3782 +0.6 1.1 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54) compare
Pf1N1B4_4621 +0.6 1.8 L-arabonate dehydratase (EC 4.2.1.25) compare
Pf1N1B4_2764 +0.6 2.2 Ferredoxin--NADP(+) reductase (EC 1.18.1.2) compare
Pf1N1B4_1003 +0.6 1.8 Tryptophan synthase beta chain like (EC 4.2.1.20) compare
Pf1N1B4_770 +0.6 1.6 hypothetical protein compare
Pf1N1B4_2464 +0.6 1.8 Ribosomal protein S6 glutaminyl transferase compare
Pf1N1B4_2062 +0.6 2.5 Uncharacterized protein ImpD compare
Pf1N1B4_5496 +0.6 1.9 hypothetical protein compare
Pf1N1B4_3713 +0.6 1.2 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) compare
Pf1N1B4_5073 +0.6 1.4 Hydroxypyruvate isomerase (EC 5.3.1.22) compare
Pf1N1B4_13 +0.6 1.9 SAM-dependent methyltransferase YafE (UbiE paralog) compare
Pf1N1B4_16 +0.6 1.8 Cys regulon transcriptional activator CysB compare
Pf1N1B4_1339 +0.6 2.0 ABC transporter (iron.B12.siderophore.hemin) , ATP-binding component compare
Pf1N1B4_1446 +0.6 1.5 Predicted hydroxymethylpyrimidine transporter CytX compare
Pf1N1B4_576 +0.6 2.3 hypothetical protein compare
Pf1N1B4_234 +0.6 1.5 hypothetical protein compare
Pf1N1B4_623 +0.6 1.1 Aminomethyltransferase (glycine cleavage system T protein) (EC 2.1.2.10) compare
Pf1N1B4_4560 +0.6 1.2 Transcriptional regulator, MerR family compare
Pf1N1B4_1671 +0.6 1.7 FIG00954962: hypothetical protein compare
Pf1N1B4_535 +0.6 2.2 FIG00953341: hypothetical protein compare
Pf1N1B4_4486 +0.6 1.4 Outer membrane protein (porin) compare
Pf1N1B4_3365 +0.6 2.3 Sialic acid transporter (permease) NanT compare
Pf1N1B4_4271 +0.6 1.4 Hydrogen cyanide synthase HcnC / Opine oxidase subunit B compare
Pf1N1B4_2637 +0.6 2.9 dTDP-4-dehydrorhamnose reductase (EC 1.1.1.133) compare
Pf1N1B4_1428 +0.6 1.7 Flagellar motor rotation protein MotB compare
Pf1N1B4_3613 +0.6 1.3 hypothetical protein compare
Pf1N1B4_648 +0.5 5.2 Outer membrane porin, OprD family compare
Pf1N1B4_63 +0.5 1.4 Phosphonoacetaldehyde phosphonohydrolase-related protein compare
Pf1N1B4_574 +0.5 1.4 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) compare
Pf1N1B4_1135 +0.5 1.4 FIG00960055: hypothetical protein compare
Pf1N1B4_5552 +0.5 1.1 hypothetical protein compare
Pf1N1B4_647 +0.5 3.3 hypothetical protein compare
Pf1N1B4_4001 +0.5 1.2 Membrane fusion component of tripartite multidrug resistance system compare
Pf1N1B4_1456 +0.5 3.4 Hypothetical protein FIG015671 in large core OS assembly cluster compare
Pf1N1B4_5468 +0.5 2.7 hypothetical protein compare
Pf1N1B4_814 +0.5 1.2 Transcriptional regulator, PadR family compare
Pf1N1B4_516 +0.5 1.6 Sensor histidine kinase compare
Pf1N1B4_3030 +0.5 2.2 Transcriptional regulators, LysR family compare
Pf1N1B4_3855 +0.5 1.8 Chromosome partition protein smc compare
Pf1N1B4_3849 +0.5 2.1 Transcriptional regulator, GntR family compare
Pf1N1B4_1457 +0.5 2.9 Hypothetical protein FIG015671 in large core OS assembly cluster compare
Pf1N1B4_4669 +0.5 0.8 Heavy metal RND efflux outer membrane protein, CzcC family compare
Pf1N1B4_6041 +0.5 0.8 Carbon storage regulator compare
Pf1N1B4_4846 +0.5 2.2 Multiple polyol-specific dehydrogenase (EC 1.1.1.-) compare
Pf1N1B4_2828 +0.5 1.8 FIG00953333: hypothetical protein compare
Pf1N1B4_1999 +0.5 1.7 FIG00957502: hypothetical protein compare
Pf1N1B4_1792 +0.5 1.2 Taurine transport ATP-binding protein TauB compare
Pf1N1B4_2036 +0.5 1.5 Phosphate transport system permease protein PstA (TC 3.A.1.7.1) compare
Pf1N1B4_4372 +0.5 1.6 Galactitol utilization operon repressor compare
Pf1N1B4_5555 +0.5 2.1 hypothetical protein compare
Pf1N1B4_4462 +0.5 1.3 LysR family transcriptional regulator YbhD compare
Pf1N1B4_1847 +0.5 2.5 hypothetical protein compare
Pf1N1B4_1901 +0.5 1.4 Putative NADH-flavin reductase compare
Pf1N1B4_5527 +0.5 2.2 hypothetical protein compare
Pf1N1B4_3023 +0.5 1.5 hypothetical protein compare
Pf1N1B4_496 +0.5 1.9 Type II/IV secretion system ATP hydrolase TadA/VirB11/CpaF, TadA subfamily compare
Pf1N1B4_656 +0.5 3.3 Glutamate N-acetyltransferase (EC 2.3.1.35) / N-acetylglutamate synthase (EC 2.3.1.1) compare
Pf1N1B4_3370 +0.5 2.2 ATPase associated with various cellular activities, AAA_5 compare
Pf1N1B4_6027 +0.5 1.5 FIG00955358: hypothetical protein compare
Pf1N1B4_765 +0.5 1.6 Cys-tRNA(Pro) deacylase YbaK compare
Pf1N1B4_21 +0.5 1.7 Probable hydrolase compare
Pf1N1B4_3382 +0.5 1.9 4-hydroxythreonine-4-phosphate dehydrogenase (EC 1.1.1.262) compare
Pf1N1B4_2866 +0.5 1.7 Periplasmic hemin-binding protein compare
Pf1N1B4_3176 +0.5 1.9 Succinylglutamate desuccinylase/aspartoacylase compare
Pf1N1B4_5647 +0.5 1.9 hypothetical protein compare
Pf1N1B4_3537 +0.5 2.1 Permease of the drug/metabolite transporter (DMT) superfamily compare
Pf1N1B4_51 +0.5 1.4 hypothetical protein compare
Pf1N1B4_4247 +0.5 1.7 D-aminopeptidase (EC 3.4.11.19) compare
Pf1N1B4_2859 +0.5 4.2 Two-component sensor CbrA: intrcellular carbon:nitrogen balance compare
Pf1N1B4_4582 +0.5 1.4 hypothetical protein compare
Pf1N1B4_3284 +0.5 2.2 Antitoxin 1 compare
Pf1N1B4_5568 +0.5 1.2 hypothetical protein compare
Pf1N1B4_3703 +0.5 1.4 NLP/P60 family protein compare
Pf1N1B4_3309 +0.5 2.4 Uracil-DNA glycosylase, family 1 compare
Pf1N1B4_215 +0.5 3.0 Pyoverdine chromophore precursor synthetase PvdL compare
Pf1N1B4_1153 +0.5 1.5 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf1N1B4_1362 +0.5 2.2 Transcriptional regulator, AraC family compare
Pf1N1B4_4900 +0.5 1.4 Alkaline proteinase inhibitor precursor compare
Pf1N1B4_2271 +0.5 1.6 ATPases of the AAA+ class compare
Pf1N1B4_3609 +0.5 2.0 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV compare
Pf1N1B4_4717 +0.5 0.9 Agmatinase (EC 3.5.3.11) compare
Pf1N1B4_3364 +0.5 0.8 Cyn operon transcriptional activator compare
Pf1N1B4_224 +0.5 1.3 Isohexenylglutaconyl-CoA hydratase compare
Pf1N1B4_201 +0.5 1.0 ABC transporter in pyoverdin gene cluster, ATP-binding component compare
Pf1N1B4_135 +0.5 1.8 Pyoverdine efflux carrier and ATP binding protein compare
Pf1N1B4_4567 +0.5 1.5 tRNA-(ms[2]io[6]A)-hydroxylase (EC 1.-.-.-) compare
Pf1N1B4_3715 +0.5 2.2 Cobalamin synthase compare
Pf1N1B4_4134 +0.5 1.1 Na+ driven multidrug efflux pump compare
Pf1N1B4_1855 +0.5 2.3 hypothetical protein compare
Pf1N1B4_1240 +0.5 3.2 LysR family transcriptional regulator PA0133 compare
Pf1N1B4_3184 +0.5 1.6 Isochorismatase (EC 3.3.2.1) compare
Pf1N1B4_5467 +0.5 2.7 Leader peptidase (Prepilin peptidase) (EC 3.4.23.43) / N-methyltransferase (EC 2.1.1.-) compare
Pf1N1B4_2237 +0.5 2.0 Ribonucleotide reductase, alpha subunit compare
Pf1N1B4_1546 +0.5 1.9 Thermonuclease family protein compare
Pf1N1B4_2418 +0.5 2.0 HTH-type transcriptional regulator BetI compare
Pf1N1B4_1504 +0.5 1.1 Acyl carrier protein compare
Pf1N1B4_3235 +0.5 1.7 Protocatechuate 3,4-dioxygenase beta chain (EC 1.13.11.3) compare
Pf1N1B4_3515 +0.5 2.3 FIG00953467: hypothetical protein compare
Pf1N1B4_1268 +0.5 1.9 Transcriptional regulator, AraC family compare


Specific Phenotypes

For 3 genes in this experiment

For stress copper (II) chloride dihydrate in Pseudomonas fluorescens FW300-N1B4

For stress copper (II) chloride dihydrate across organisms