Experiment set1IT042 for Sinorhizobium meliloti 1021

Compare to:

LB with Paraquat dichloride 0.05 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
SMc03069 +6.3 25.8 6-phosphogluconolactonase compare
SMc02659 +6.1 33.8 GTP pyrophosphokinase (ATP:GTP 3'-pyrophosphotransferase) protein compare
SMc00647 +5.9 33.2 ribosomal large subunit pseudouridine synthase compare
SMc00349 +5.9 44.7 GTP-binding protein LepA compare
SMc02112 +5.4 32.7 hypothetical protein compare
SMc04003 +5.3 12.0 50S ribosomal protein L36 compare
SMc02695 +4.9 32.9 GTP-dependent nucleic acid-binding protein EngD compare
SMc00565 +4.9 8.2 50S ribosomal protein L9 compare
SMc02137 +4.7 30.7 ornithine carbamoyltransferase compare
SMc03826 +4.5 20.5 argininosuccinate synthase compare
SMc01099 +4.5 16.9 tRNA pseudouridine synthase A compare
SMc00131 +4.4 35.3 transcriptional regulator compare
SMc01206 +4.4 16.1 queuine tRNA-ribosyltransferase compare
SMc00566 +4.2 7.3 hypothetical protein compare
SMc00150 +4.0 38.1 hypothetical protein compare
SMc01124 +4.0 10.6 PII uridylyl-transferase compare
SMc02558 +3.9 16.3 hypothetical protein compare
SMc02050 +3.9 18.9 trigger factor compare
SMc03863 +3.8 4.1 50S ribosomal protein L19 compare
SMc03900 +3.8 32.8 cyclic beta-1,2-glucan ABc transporter compare
SMc04382 +3.7 30.1 beta-(1,2)-glucan production associated transmembrane protein compare
SMc03855 +3.6 18.4 hypothetical protein compare
SMc00419 +3.6 21.1 glutathione synthetase compare
SMc00711 +3.6 21.9 cyclohexadienyl dehydrogenase compare
SMc04385 +3.4 25.8 L-2-aminoadipate semialdehyde dehydrogenase (EC 1.2.1.31) (from data) compare
SMc00458 +3.4 27.5 transcriptional regulator compare
SMc01215 +3.4 15.3 carbamoyl phosphate synthase large subunit compare
SMc00427 +3.4 16.5 peptide chain release factor RF-3 protein compare
SMc01275 +3.3 9.2 ribosomal large subunit pseudouridine synthase C protein compare
SMc04094 +3.2 12.0 hypothetical protein compare
SMc00495 +3.1 11.7 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
SMc01569 +3.1 12.2 carbamoyl phosphate synthase small subunit compare
SMc02365 +3.1 11.1 protease precursor protein compare
SMc02367 +3.0 21.9 sensor histidine kinase transmembrane protein compare
SMc02366 +2.9 23.2 transcriptional regulator compare
SMc02095 +2.8 14.1 hypothetical protein compare
SMc02138 +2.7 7.9 acetylornithine transaminase compare
SMc01801 +2.6 5.7 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) compare
SMa2020 +2.6 11.8 Transcriptional regulator compare
SMc00320 +2.5 9.3 ribosome-binding factor A compare
SMc02055 +2.5 3.8 phytoene synthase compare
SMc04454 +2.5 14.0 ABC transporter ATP-binding protein compare
SMc03157 +2.4 14.4 outer membrane lipoprotein transmembrane compare
SMc02503 +2.4 10.6 hypothetical protein compare
SMc00522 +2.4 17.3 ATP-dependent RNA helicase compare
SMc01207 +2.4 6.9 S-adenosylmethionine--tRNA ribosyltransferase-isomerase compare
SMc03159 +2.3 4.5 ABC transporter ATP-binding protein compare
SMc02166 +2.3 17.3 dihydroorotase compare
SMc00321 +2.2 11.1 tRNA pseudouridine synthase B compare
SMc00129 +2.2 11.9 sensor histidine kinase compare
SMc01726 +2.2 13.6 acetylglutamate kinase compare
SMc00009 +2.1 7.3 cytochrome C oxidase subunit II protein compare
SMc04383 +2.1 9.3 putative hydrolase, required for lysine catabolism (from data) compare
SM_b20146 +2.0 5.4 pyridoxal phosphate biosynthetic protein compare
SMc01907 +2.0 15.2 hypothetical protein compare
SMc02755 +2.0 9.1 S-adenosyl-L-homocysteine hydrolase compare
SMc02309 +2.0 9.7 arsenate reductase compare
SMc00450 +2.0 6.8 protoheme IX farnesyltransferase compare
SMc00761 +2.0 14.0 oxidoreductase compare
SMc04235 +2.0 12.0 tRNA-dihydrouridine synthase A compare
SMc01439 +2.0 7.9 hypothetical protein compare
SMc04001 +1.9 3.1 phosphoribosylaminoimidazole carboxylase catalytic subunit protein compare
SMc00482 +1.9 9.9 hypothetical protein compare
SMc02757 +1.9 3.2 hypothetical protein compare
SM_b20613 +1.9 13.8 C4-dicarboxylate transport transcriptional regulator compare
SMc02245 +1.9 9.2 dihydroorotate dehydrogenase 2 compare
SMc00403 +1.9 12.4 NOL1/NOP2/SUN family signature protein compare
SMc03111 +1.9 10.3 mannose 6-phosphate isomerase (EC 5.3.1.8) (from data) compare
SMc00169 +1.8 15.7 malic enzyme compare
SMc02640 +1.8 8.6 UDP-glucuronic acid epimerase compare
SMc03933 +1.8 15.5 sarcosine oxidase subunit B protein compare
SMc00070 +1.8 6.2 signal peptide protein compare
SMc03973 +1.8 8.7 hypothetical protein compare
SMc04000 +1.8 2.8 hypothetical protein compare
SMc02246 +1.8 2.5 hypothetical protein compare
SMc00998 +1.7 12.6 signal peptide protein compare
SMc01858 +1.7 3.2 S-adenosyl-methyltransferase MraW compare
SMc00622 +1.7 11.2 ribonuclease D protein compare
SMc03158 +1.7 5.6 ABC transporter permease compare
SMc03930 +1.7 3.2 sarcosine oxidase subunit gamma compare
SMc02504 +1.6 7.9 transcriptional regulator compare
SMc03931 +1.6 14.4 sarcosine oxidase subunit alpha compare
SMc01613 +1.6 5.5 ribose-5-phosphate isomerase B compare
SMc00710 +1.6 5.6 histidinol-phosphate aminotransferase compare
SMc00187 +1.6 6.7 ubiquinol-cytochrome C reductase iron-sulfur subunit protein compare
SMc01120 +1.6 3.8 hypothetical protein compare
SMc01223 +1.6 4.9 transcriptional regulator compare
SMc00017 +1.6 4.3 homoserine kinase compare
SMc03932 +1.6 9.6 sarcosine oxidase subunit delta compare
SMc00727 +1.6 10.2 3-hydroxybutyryl-CoA dehydrogenase compare
SMc01222 +1.6 5.4 lipopolysaccharide core biosynthesis glycosyl transferase compare
SMc01852 +1.5 10.5 pyrophosphate--fructose-6-phosphate 1-phosphotransferase compare
SMc00648 +1.5 7.6 hypothetical protein compare
SM_b21397 +1.5 1.5 hypothetical protein compare
SMc02058 +1.5 2.1 YAJC protein compare
SMc02056 +1.4 3.6 hypothetical protein compare
SM_b20131 +1.4 1.2 oxidoreductase compare
SMc00412 +1.4 5.7 orotidine 5'-phosphate decarboxylase compare
SM_b21265 +1.4 5.7 glycosyltransferase compare
SMc01768 +1.4 7.2 transcriptional regulator compare
SMc02384 +1.4 5.7 glycosyltransferase transmembrane protein compare
SM_b21170 +1.3 8.1 guanylate kinase compare
SMc02766 +1.3 10.5 tryptophan synthase subunit beta compare
SMc00329 +1.3 6.4 iron response regulator protein compare
SMc02765 +1.3 8.7 tryptophan synthase subunit alpha compare
SM_b21192 +1.2 8.9 fructose-1,6-bisphosphate aldolase compare
SM_b21374 +1.2 5.4 tagatose kinase (EC 2.7.1.101) (from data) compare
SMc01933 +1.2 1.6 hypothetical protein compare
SMc04384 +1.2 2.7 (R)-2-hydroxyglutarate dehydrogenase (EC 1.1.99.39) (from data) compare
SMc00010 +1.2 1.8 cytochrome C oxidase polypeptide I transmembrane protein compare
SMa1365 +1.2 2.7 ATP-binding protein compare
SMc02858 +1.2 1.2 chaperone protein DnaJ compare
SM_b20684 +1.1 9.5 hypothetical protein compare
SMc01698 +1.1 5.6 oxidoreductase compare
SMc03153 +1.1 4.2 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase compare
SMc03996 +1.1 4.4 thiamine-phosphate pyrophosphorylase compare
SMc04391 +1.1 2.2 3-ketoacyl-ACP reductase compare
SMc01256 +1.1 8.1 L-serine dehydratase compare
SMc02906 +1.1 1.1 hypothetical protein compare
SMc00325 +1.1 6.3 hypothetical protein compare
SMc01193 +1.1 7.5 hypothetical protein compare
SM_b21264 +1.0 7.8 hypothetical protein compare
SMc03880 +1.0 6.9 hypothetical protein compare
SMc01800 +1.0 2.1 cytochrome C oxidase assembly transmembrane protein compare
SMc04002 +1.0 3.6 phosphoribosylaminoimidazole carboxylase ATPase subunit compare
SMc02478 +1.0 6.3 hypothetical protein compare
SM_b21491 +1.0 7.2 hypothetical protein compare
SMc01440 +1.0 4.0 hydrolase serine protease transmembrane protein compare
SMc01153 +1.0 1.7 enoyl-CoA hydratase compare
SM_b20751 +1.0 1.9 3-hydroxyisobutyrate dehydrogenase compare
SM_b20294 +1.0 2.0 transcriptional regulator NanR compare
SMc00576 +1.0 1.7 hypothetical protein compare
SMc02793 +1.0 5.9 hypothetical protein compare
SM_b21256 +1.0 7.5 nucleotide sugar oxidase compare
SMc04232 +1.0 1.7 glycine rich transmembrane protein compare
SMc04441 +1.0 1.5 hypothetical protein compare
SM_b21266 +1.0 5.1 hypothetical protein compare
SMc00800 +0.9 2.2 hypothetical protein compare
SM_b20819 +0.9 2.2 ferredoxin compare
SMc02575 +0.9 4.8 ATP-dependent protease peptidase subunit compare
SMc02136 +0.9 5.3 Hsp33-like chaperonin compare
SMc02983 +0.9 5.8 ornithine, DAP, or arginine decarboxylase compare
SMc04092 +0.9 1.4 hypothetical protein compare
SM_b21487 +0.9 5.3 cytochrome o ubiquinol oxidase subunit II compare
SMc02273 +0.9 8.2 fatty acid synthase transmembrane protein compare
SMc00361 +0.9 3.1 hypothetical protein compare
SMc01273 +0.9 7.4 S-formylglutathione hydrolase compare
SMc00789 +0.9 4.6 peptide ABC transporter ATP-binding protein compare
SMa0854 +0.9 1.1 3-ketoacyl-ACP reductase compare
SMc00075 +0.9 2.9 ribosomal-protein-alanine acetyltransferase compare
SMc01178 +0.9 2.0 multidrug transmembrane resistance signal peptide protein compare
SM_b21208 +0.9 2.1 TetR family transcriptional regulator compare
SMc00026 +0.9 4.3 hypothetical protein compare
SM_b21372 +0.9 6.4 LacI family transcriptional regulator compare
SMc01006 +0.9 3.8 hypothetical protein compare
SM_b20757 +0.9 4.8 methylmalonyl-CoA mutase compare
SMc03792 +0.8 1.1 hypothetical protein compare
SMc01315 +0.8 1.4 hypothetical protein compare
SMa5036 +0.8 3.3 hypothetical protein compare
SMc04882 +0.8 1.7 transcriptional regulator compare
SMc00012 +0.8 1.2 cytochrome C oxidase assembly protein compare
SMc04348 +0.8 2.3 transcriptional regulator compare
SMc02181 +0.8 6.2 bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase compare
SMc02272 +0.8 5.8 acyl-transferase transferase compare
SMc01139 +0.8 4.0 RNA polymerase factor sigma-54 compare
SMc00061 +0.8 3.7 hypothetical protein compare
SMc02057 +0.8 4.2 preprotein translocase subunit SecD/SecF compare
SMc02714 +0.8 1.5 hypothetical protein compare
SMc01007 +0.8 2.3 hypothetical protein compare
SM_b21347 +0.8 2.0 pectin degradation protein compare
SMc01939 +0.8 1.1 urease subunit beta compare
SMa5000 +0.8 1.2 hypothetical protein compare
SMc00709 +0.8 3.4 hypothetical protein compare
SMc01108 +0.8 3.9 tRNA (guanine-N(7)-)-methyltransferase compare
SMc02383 +0.8 5.8 hypothetical protein compare
SMc03780 +0.8 3.3 hypothetical protein compare
SMc03037 +0.8 1.0 flagellin A compare
SMc02577 +0.8 4.9 ATP-dependent protease ATP-binding subunit HslU compare
SM_b21181 +0.8 3.3 glutaryl-CoA dehydrogenase compare
SMc02241 +0.8 4.6 hypothetical protein compare
SMa2029 +0.8 1.2 amidohydrolase compare
SMc01272 +0.8 3.1 hypothetical protein compare
SMc01987 +0.8 6.2 dehydrogenase compare
SMc00554 +0.8 3.1 amidophosphoribosyltransferase compare
SMc00247 +0.8 5.6 phosphatidylcholine synthase compare
SM_b21253 +0.8 5.0 hypothetical protein compare
SMc02052 +0.8 0.9 hypothetical protein compare
SMc00093 +0.8 5.8 choline dehydrogenase compare
SM_b21252 +0.8 6.2 glycosyltransferase compare
SMc05020 +0.8 1.9 entericidin A precursor compare
SMc00029 +0.7 2.5 hypothetical protein compare
SM_b20145 +0.7 1.4 hypothetical protein compare
SMc00877 +0.7 4.8 transcriptional regulator compare
SM_b20043 +0.7 5.8 hypothetical protein compare
SMc04239 +0.7 2.0 hypothetical protein compare
SMc02684 +0.7 3.3 hydrolase/peptidase compare
SM_b20815 +0.7 1.2 outer membrane protein assembly protein compare
SMc04381 +0.7 3.1 hypothetical protein compare
SMc03050 +0.7 1.3 flagellar biosynthesis regulatory protein FlaF compare
SMc04005 +0.7 4.7 pyruvate kinase compare


Specific Phenotypes

For 4 genes in this experiment

For stress Paraquat dichloride in Sinorhizobium meliloti 1021

For stress Paraquat dichloride across organisms