Experiment set1IT040 for Pseudomonas fluorescens FW300-N2E2

Compare to:

LB with Cisplatin 0.008 mg/ml

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_2129 -7.7 -5.3 Predicted dye-decolorizing peroxidase (DyP), YfeX-like subgroup compare
Pf6N2E2_4071 -7.3 -5.1 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_4197 -7.1 -8.4 DNA recombination and repair protein RecF compare
Pf6N2E2_2325 -6.3 -4.4 Recombination protein RecR compare
Pf6N2E2_4888 -5.8 -25.8 Excinuclease ABC subunit A conserved
Pf6N2E2_2523 -5.7 -14.1 Methylthioribose-1-phosphate isomerase (EC 5.3.1.23) conserved
Pf6N2E2_3370 -5.6 -17.5 DNA repair protein RecN conserved
Pf6N2E2_5001 -5.5 -3.8 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) compare
Pf6N2E2_2021 -5.5 -11.2 Excinuclease ABC subunit C conserved
Pf6N2E2_2992 -5.5 -7.1 Regulatory protein RecX compare
Pf6N2E2_52 -5.4 -18.2 Excinuclease ABC subunit B conserved
Pf6N2E2_5679 -5.2 -7.9 hypothetical protein compare
Pf6N2E2_5430 -5.1 -13.0 Transglycosylase, Slt family compare
Pf6N2E2_5428 -5.0 -9.0 DNA recombination and repair protein RecO compare
Pf6N2E2_4077 -5.0 -3.1 cytosolic long-chain acyl-CoA thioester hydrolase family protein compare
Pf6N2E2_4352 -4.9 -3.4 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf6N2E2_3460 -4.5 -3.0 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_3908 -4.4 -9.4 Glutamate--cysteine ligase (EC 6.3.2.2) compare
Pf6N2E2_3351 -4.2 -7.6 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
Pf6N2E2_5006 -4.2 -10.9 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_3137 -4.1 -12.9 Single-stranded-DNA-specific exonuclease RecJ (EC 3.1.-.-) conserved
Pf6N2E2_5527 -4.1 -4.3 Cold shock protein CspC compare
Pf6N2E2_4673 -4.0 -4.1 ATP-dependent 23S rRNA helicase DbpA compare
Pf6N2E2_2217 -4.0 -7.5 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_621 -3.7 -8.1 TPR domain protein in aerotolerance operon compare
Pf6N2E2_4072 -3.7 -7.2 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
Pf6N2E2_4162 -3.6 -2.5 DNA polymerase I (EC 2.7.7.7) compare
Pf6N2E2_4369 -3.5 -3.4 Exodeoxyribonuclease III (EC 3.1.11.2) compare
Pf6N2E2_4273 -3.4 -6.4 ATP-dependent DNA helicase UvrD/PcrA compare
Pf6N2E2_2942 -3.3 -12.9 ATP-dependent helicase DinG/Rad3 conserved
Pf6N2E2_4204 -3.3 -2.5 rRNA small subunit 7-methylguanosine (m7G) methyltransferase GidB compare
Pf6N2E2_2278 -3.3 -17.1 Transcription-repair coupling factor compare
Pf6N2E2_3612 -3.1 -4.2 HflK protein compare
Pf6N2E2_5342 -3.1 -5.1 21 kDa hemolysin precursor compare
Pf6N2E2_2574 -2.9 -3.0 Flagellar synthesis regulator FleN compare
Pf6N2E2_4075 -2.9 -7.6 Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1) compare
Pf6N2E2_4416 -2.8 -4.7 Tyrosine recombinase XerC compare
Pf6N2E2_4797 -2.8 -2.1 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_5076 -2.7 -5.4 DNA repair protein RadA conserved
Pf6N2E2_3461 -2.7 -1.7 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_2675 -2.6 -1.6 ATP-dependent RNA helicase SrmB compare
Pf6N2E2_1226 -2.6 -9.4 DNA damage response nuclease (from data) conserved
Pf6N2E2_620 -2.6 -9.5 BatD compare
Pf6N2E2_624 -2.6 -7.0 hypothetical protein PA3071 compare
Pf6N2E2_5160 -2.5 -2.2 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_1225 -2.5 -12.5 DinG family ATP-dependent helicase CPE1197 conserved
Pf6N2E2_5711 -2.4 -8.0 tRNA(Cytosine32)-2-thiocytidine synthetase conserved
Pf6N2E2_4612 -2.4 -3.6 Glutathione synthetase (EC 6.3.2.3) compare
Pf6N2E2_4453 -2.3 -15.0 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_5155 -2.3 -4.2 Poly(A) polymerase (EC 2.7.7.19) compare
Pf6N2E2_3062 -2.3 -4.8 Membrane-associated zinc metalloprotease compare
Pf6N2E2_3264 -2.2 -4.0 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_4353 -2.2 -6.6 Hydrogen peroxide-inducible genes activator compare
Pf6N2E2_625 -2.2 -5.0 MoxR-like ATPase in aerotolerance operon compare
Pf6N2E2_3617 -2.2 -6.1 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) compare
Pf6N2E2_3834 -2.2 -6.5 Lipoprotein NlpD compare
Pf6N2E2_622 -2.1 -5.2 BatA (Bacteroides aerotolerance operon) compare
Pf6N2E2_2645 -2.1 -5.3 ATP-dependent DNA helicase RecQ conserved
Pf6N2E2_159 -2.0 -4.7 DNA damage resistance protein (from data) compare
Pf6N2E2_5340 -2.0 -5.0 Stringent starvation protein A compare
Pf6N2E2_178 -2.0 -1.5 Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) compare
Pf6N2E2_2218 -1.9 -4.9 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_5245 -1.9 -5.4 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_5172 -1.9 -4.7 FOG: TPR repeat compare
Pf6N2E2_3782 -1.9 -3.6 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_2285 -1.9 -2.1 FIG00954079: hypothetical protein compare
Pf6N2E2_3095 -1.8 -1.7 hypothetical protein compare
Pf6N2E2_4272 -1.8 -3.9 putative membrane protein compare
Pf6N2E2_5014 -1.8 -1.6 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_4074 -1.7 -10.0 Phosphate transport system permease protein PstC (TC 3.A.1.7.1) compare
Pf6N2E2_2973 -1.7 -3.2 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_3349 -1.7 -4.2 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_1652 -1.7 -3.9 Transcriptional regulator, TetR family compare
Pf6N2E2_3261 -1.7 -3.6 hypothetical protein compare
Pf6N2E2_2427 -1.7 -7.9 DNA damage response gene with a putative DNA binding domain and often regulated by LexA (PA0922-like) (from data) conserved
Pf6N2E2_5219 -1.7 -7.6 FIG140336: TPR domain protein compare
Pf6N2E2_4205 -1.6 -3.8 Chromosome (plasmid) partitioning protein ParA compare
Pf6N2E2_5252 -1.6 -1.4 FIG00956396: hypothetical protein compare
Pf6N2E2_3835 -1.6 -3.5 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf6N2E2_3611 -1.6 -1.8 HflC protein compare
Pf6N2E2_5520 -1.6 -5.7 Sensory box histidine kinase compare
Pf6N2E2_4206 -1.6 -2.2 Chromosome (plasmid) partitioning protein ParB compare
Pf6N2E2_623 -1.6 -1.6 FIG00954674: hypothetical protein compare
Pf6N2E2_5861 -1.5 -7.1 FIG00953885: hypothetical protein compare
Pf6N2E2_3134 -1.5 -1.2 hypothetical protein compare
Pf6N2E2_4362 -1.5 -3.7 DNA-directed RNA polymerase omega subunit (EC 2.7.7.6) compare
Pf6N2E2_288 -1.5 -2.4 Isocitrate dehydrogenase [NADP] (EC 1.1.1.42); Monomeric isocitrate dehydrogenase [NADP] (EC 1.1.1.42) compare
Pf6N2E2_5534 -1.4 -3.4 FIG000859: hypothetical protein YebC compare
Pf6N2E2_2428 -1.4 -3.0 Thiol-disulfide isomerase and thioredoxins compare
Pf6N2E2_2640 -1.4 -1.9 Permease of the drug/metabolite transporter (DMT) superfamily compare
Pf6N2E2_74 -1.4 -2.7 DedD protein compare
Pf6N2E2_4155 -1.4 -7.9 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) compare
Pf6N2E2_5768 -1.4 -3.4 DNA recombination-dependent growth factor C compare
Pf6N2E2_3607 -1.4 -5.6 3'-to-5' exoribonuclease RNase R compare
Pf6N2E2_3260 -1.4 -3.6 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
Pf6N2E2_2750 -1.3 -4.4 Putative permease PerM (= YfgO) compare
Pf6N2E2_3833 -1.3 -4.6 hypothetical protein compare
Pf6N2E2_2503 -1.3 -1.8 Glycosyl transferase, group 1 family protein compare
Pf6N2E2_5671 -1.3 -3.1 Succinylglutamate desuccinylase (EC 3.5.1.96) compare
Pf6N2E2_3255 -1.3 -3.3 YrbA protein compare
Pf6N2E2_2510 -1.3 -3.6 Lipid carrier : UDP-N-acetylgalactosaminyltransferase (EC 2.4.1.-) / Alpha-1,3-N-acetylgalactosamine transferase PglA (EC 2.4.1.-); Putative glycosyltransferase compare
Pf6N2E2_5103 -1.3 -1.6 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
Pf6N2E2_4710 -1.3 -1.5 hypothetical protein compare
Pf6N2E2_4733 -1.3 -1.7 hypothetical protein compare
Pf6N2E2_613 -1.2 -1.7 lipoprotein, putative compare
Pf6N2E2_2292 -1.2 -3.7 Universal stress protein family COG0589 compare
Pf6N2E2_4886 -1.2 -7.7 Catalase (EC 1.11.1.6) compare
Pf6N2E2_2274 -1.2 -3.6 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) compare
Pf6N2E2_1545 -1.2 -4.2 N-carbamoylputrescine amidase (EC 3.5.1.53) compare
Pf6N2E2_4477 -1.2 -3.0 Z-ring-associated protein ZapA compare
Pf6N2E2_2753 -1.2 -2.1 HtrA protease/chaperone protein compare
Pf6N2E2_3505 -1.2 -1.9 Translation initiation factor SUI1-related protein compare
Pf6N2E2_5178 -1.2 -1.7 CDP-diacylglycerol--serine O-phosphatidyltransferase (EC 2.7.8.8) compare
Pf6N2E2_3039 -1.1 -6.2 Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) compare
Pf6N2E2_3504 -1.1 -6.3 Biosynthetic arginine decarboxylase (EC 4.1.1.19) compare
Pf6N2E2_5723 -1.1 -5.8 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
Pf6N2E2_4474 -1.1 -7.3 FIG006231: RNA-binding protein compare
Pf6N2E2_5506 -1.1 -6.3 Exodeoxyribonuclease I (EC 3.1.11.1) conserved
Pf6N2E2_5242 -1.1 -1.7 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_6099 -1.1 -1.3 tRNA-Glu-TTC compare
Pf6N2E2_4527 -1.1 -1.3 RNA polymerase sigma-70 factor, ECF subfamily compare
Pf6N2E2_4417 -1.1 -2.3 Protein of unknown function DUF484 compare
Pf6N2E2_2527 -1.1 -4.3 Oxidoreductase, short chain dehydrogenase/reductase family compare
Pf6N2E2_672 -1.1 -2.3 ABC-type polar amino acid transport system, ATPase component compare
Pf6N2E2_3941 -1.1 -2.6 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf6N2E2_5301 -1.1 -3.8 FIG00957554: hypothetical protein compare
Pf6N2E2_4599 -1.1 -2.7 Integral membrane protein YggT, involved in response to extracytoplasmic stress (osmotic shock) compare
Pf6N2E2_4601 -1.0 -2.0 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC compare
Pf6N2E2_3876 -1.0 -2.5 Agmatine deiminase (EC 3.5.3.12) compare
Pf6N2E2_4987 -1.0 -1.1 MaoC-like domain protein compare
Pf6N2E2_5793 -1.0 -5.4 Aspartyl aminopeptidase compare
Pf6N2E2_4418 -1.0 -0.8 Diaminopimelate epimerase (EC 5.1.1.7) compare
Pf6N2E2_4638 -1.0 -2.5 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_3984 -1.0 -6.4 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_3534 -1.0 -1.9 Cobalamin biosynthesis protein CobG compare
Pf6N2E2_3040 -1.0 -3.9 5-nucleotidase SurE (EC 3.1.3.5) compare
Pf6N2E2_127 -1.0 -1.5 AttE component of AttEFGH ABC transport system compare
Pf6N2E2_319 -1.0 -1.8 DUF1850 domain-containing protein compare
Pf6N2E2_2375 -1.0 -1.7 Response regulator NasT compare
Pf6N2E2_4889 -1.0 -3.0 Putative transport protein compare
Pf6N2E2_5111 -1.0 -1.8 FKBP-type peptidyl-prolyl cis-trans isomerase SlpA (EC 5.2.1.8) compare
Pf6N2E2_2128 -0.9 -2.8 Short-chain dehydrogenase/reductase SDR compare
Pf6N2E2_1396 -0.9 -1.0 ABC transporter, ATP-binding protein compare
Pf6N2E2_2180 -0.9 -3.2 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_2317 -0.9 -3.4 Putative analog of CcoH, COG3198 compare
Pf6N2E2_4609 -0.9 -2.5 UPF0301 protein YqgE compare
Pf6N2E2_282 -0.9 -1.5 GNAT family acetyltransferase YjcF compare
Pf6N2E2_1323 -0.9 -2.4 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) compare
Pf6N2E2_4584 -0.9 -2.7 Cell division transporter, ATP-binding protein FtsE (TC 3.A.5.1.1) compare
Pf6N2E2_2068 -0.9 -4.3 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) compare
Pf6N2E2_5389 -0.9 -5.0 UPF0246 protein YaaA compare
Pf6N2E2_2646 -0.9 -1.0 FIG00953416: hypothetical protein compare
Pf6N2E2_4146 -0.9 -1.7 Membrane lipoprotein lipid attachment site containing protein USSDB6D compare
Pf6N2E2_4073 -0.9 -2.4 Phosphate transport system permease protein PstA (TC 3.A.1.7.1) compare
Pf6N2E2_2367 -0.9 -1.8 hypothetical protein compare
Pf6N2E2_4585 -0.9 -5.4 Cell division protein FtsX compare
Pf6N2E2_180 -0.9 -1.7 Transcriptional regulator, MerR family compare
Pf6N2E2_5240 -0.9 -3.9 FIG00953775: hypothetical protein compare
Pf6N2E2_1394 -0.9 -3.3 FIG00953323: hypothetical protein compare
Pf6N2E2_2487 -0.9 -0.9 FIG00956090: hypothetical protein compare
Pf6N2E2_4351 -0.9 -5.0 Predicted signal transduction protein compare
Pf6N2E2_5453 -0.9 -3.3 hypothetical protein compare
Pf6N2E2_3625 -0.8 -4.8 Flagellar motor rotation protein MotA compare
Pf6N2E2_3258 -0.8 -3.0 Uncharacterized ABC transporter, periplasmic component YrbD compare
Pf6N2E2_142 -0.8 -2.4 Exodeoxyribonuclease III (EC 3.1.11.2) compare
Pf6N2E2_4478 -0.8 -3.4 FIG019278: hypothetical protein compare
Pf6N2E2_4181 -0.8 -1.0 Organic hydroperoxide resistance protein compare
Pf6N2E2_5494 -0.8 -2.2 Pyruvate kinase (EC 2.7.1.40) compare
Pf6N2E2_4147 -0.8 -4.6 Fused spore maturation proteins A and B compare
Pf6N2E2_4636 -0.8 -3.5 periplasmic binding protein, putative compare
Pf6N2E2_5936 -0.8 -1.9 Low molecular weight protein tyrosine phosphatase (EC 3.1.3.48) compare
Pf6N2E2_2106 -0.8 -1.0 hypothetical protein compare
Pf6N2E2_5044 -0.8 -1.5 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system compare
Pf6N2E2_5816 -0.8 -1.4 Smr domain protein compare
Pf6N2E2_218 -0.8 -2.7 hypothetical protein compare
Pf6N2E2_2941 -0.8 -4.0 Esterase A compare
Pf6N2E2_3911 -0.8 -3.4 Taurine transport system permease protein TauC compare
Pf6N2E2_4372 -0.8 -2.8 FIG00460773: hypothetical protein compare
Pf6N2E2_5712 -0.8 -3.5 DNA-3-methyladenine glycosylase (EC 3.2.2.20) compare
Pf6N2E2_1606 -0.8 -4.0 Carboxynorspermidine decarboxylase, putative (EC 4.1.1.-) compare
Pf6N2E2_1641 -0.8 -3.1 Chemotaxis protein CheC -- inhibitor of MCP methylation compare
Pf6N2E2_2181 -0.8 -1.0 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_2125 -0.8 -2.8 hypothetical protein compare
Pf6N2E2_4084 -0.8 -3.6 Transcriptional regulator compare
Pf6N2E2_3079 -0.8 -4.4 Cysteine desulfurase CsdA-CsdE (EC 2.8.1.7), main protein CsdA compare
Pf6N2E2_2974 -0.8 -4.0 DNA polymerase IV (EC 2.7.7.7) compare
Pf6N2E2_3190 -0.8 -3.5 Iron-sulfur cluster regulator IscR compare
Pf6N2E2_2261 -0.8 -4.3 VacJ-like lipoprotein precursor compare
Pf6N2E2_3077 -0.8 -1.8 FIG138056: a glutathione-dependent thiol reductase compare
Pf6N2E2_5987 -0.7 -3.5 OmpA family protein compare
Pf6N2E2_5780 -0.7 -4.4 Periplasmic protease compare
Pf6N2E2_5337 -0.7 -2.8 Ubiquinol-cytochrome C reductase iron-sulfur subunit (EC 1.10.2.2) compare
Pf6N2E2_4165 -0.7 -3.2 Zinc ABC transporter, periplasmic-binding protein ZnuA compare
Pf6N2E2_4615 -0.7 -1.3 type IV pili signal transduction protein PilI compare
Pf6N2E2_3009 -0.7 -1.9 Phage tail tube protein compare
Pf6N2E2_4562 -0.7 -1.4 L-cystine uptake protein TcyP compare
Pf6N2E2_4307 -0.7 -2.3 Type VI secretion lipoprotein/VasD compare
Pf6N2E2_2266 -0.7 -1.8 Copper-sensing two-component system response regulator CusR compare
Pf6N2E2_4399 -0.7 -3.1 GGDEF domain/EAL domain protein compare
Pf6N2E2_5756 -0.7 -2.2 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare


Specific Phenotypes

For 18 genes in this experiment

For stress Cisplatin in Pseudomonas fluorescens FW300-N2E2

For stress Cisplatin across organisms