Experiment set1IT040 for Sinorhizobium meliloti 1021

Compare to:

LB with copper (II) chloride dihydrate 1 mM

200 most important genes:

  gene name fitness t score description  
SMc00917 -6.8 -6.5 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
SMc02641 -6.4 -6.2 UDP-glucose 6-dehydrogenase compare
SMc02144 -5.8 -6.9 phosphate ABC transporter permease compare
SMc02147 -5.8 -10.4 phosphate regulon sensor histidine kinase transmembrane protein compare
SMc02142 -5.5 -7.2 phosphate transporter ATP-binding protein compare
SMc00619 -5.4 -3.4 hypothetical protein compare
SMc02640 -4.9 -5.8 UDP-glucuronic acid epimerase compare
SMc02140 -4.7 -2.0 phosphate regulon transcriptional regulatory protein compare
SMc03763 -4.6 -4.5 cytosine-specific methyltransferase compare
SMc02569 -4.6 -3.8 imidazole glycerol phosphate synthase subunit HisF compare
SMc02753 -4.4 -2.0 PTS system transporter subunit IIA compare
SMc03967 -4.3 -2.3 Holliday junction resolvase compare
SMc02307 -4.3 -10.7 histidinol dehydrogenase compare
SMa0789 -4.2 -5.9 GntR family transcriptional regulator compare
SMc01850 -4.2 -5.3 hypothetical protein compare
SMc02570 -4.2 -10.6 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
SMc02149 -4.1 -2.6 hypothetical protein compare
SMc00918 -4.1 -7.9 ATP phosphoribosyltransferase regulatory subunit compare
SMc02572 -3.9 -5.5 imidazole glycerol phosphate synthase subunit HisH compare
SMc00450 -3.9 -2.6 protoheme IX farnesyltransferase compare
SMc01004 -3.9 -12.0 phosphoribosyl-AMP cyclohydrolase compare
SMc04385 -3.6 -5.7 L-2-aminoadipate semialdehyde dehydrogenase (EC 1.2.1.31) (from data) compare
SMc01007 -3.6 -2.7 hypothetical protein compare
SMc02867 -3.5 -5.7 multidrug-efflux system transmembrane protein compare
SMc00492 -3.4 -1.5 hypothetical protein compare
SMc03973 -3.4 -8.7 hypothetical protein compare
SMc03839 -3.2 -2.9 hypothetical protein compare
SMc02145 -3.1 -1.4 signal peptide protein compare
SMc01880 -3.1 -4.8 pantoate--beta-alanine ligase compare
SMc00914 -3.1 -5.8 oxidoreductase compare
SMc02868 -3.0 -6.3 multidrug efflux system protein compare
SMc01568 -3.0 -1.7 hypothetical protein compare
SMc02856 -3.0 -12.5 penicillin-binding protein compare
SMc04296 -3.0 -1.9 cell division protein FtsZ compare
SM_b20880 -3.0 -9.5 ATP-dependent RNA helicase compare
SMc02850 -2.9 -5.3 DNA polymerase I compare
SMc00419 -2.9 -5.8 glutathione synthetase compare
SM_b20758 -2.9 -2.8 ArsR family transcriptional regulator compare
SMc00334 -2.8 -3.0 cytidylate kinase compare
SMc00010 -2.8 -2.1 cytochrome C oxidase polypeptide I transmembrane protein compare
SMc02143 -2.7 -3.9 phosphate ABC transporter permease compare
SMc01147 -2.7 -4.6 coproporphyrinogen III oxidase compare
SMc01881 -2.6 -4.8 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
SMc03978 -2.6 -3.4 transketolase compare
SMc00511 -2.5 -8.4 D-ribulose-5-phosphate 3-epimerase compare
SMc01183 -2.5 -2.1 LexA repressor compare
SMc00712 -2.5 -2.5 hypothetical protein compare
SMc03242 -2.4 -3.1 GTP-binding protein compare
SMc04085 -2.4 -6.6 hypothetical protein compare
SMc02363 -2.4 -3.9 cytochrome C-type biogenesis transmembrane protein compare
SMc01845 -2.3 -2.5 transglycosylase transmembrane protein compare
SMc02833 -2.3 -3.2 penicillin-insensitive murein endopeptidase compare
SMc01207 -2.3 -3.6 S-adenosylmethionine--tRNA ribosyltransferase-isomerase compare
SMc01144 -2.2 -5.2 ribonuclease PH compare
SMc00302 -2.2 -3.1 hypothetical protein compare
SMc00876 -2.2 -5.5 ATP-binding MRP protein compare
SM_b21489 -2.1 -4.7 cytochrome O ubiquinol oxidase subunit III compare
SMc01258 -2.1 -6.8 hypothetical protein compare
SMc02497 -2.1 -2.5 hypothetical protein compare
SMc01206 -2.0 -1.8 queuine tRNA-ribosyltransferase compare
SM_b20955 -2.0 -3.9 endo-beta-1,3-1,4-glycanase compare
SM_b21488 -2.0 -11.9 cytochrome o ubiquinol oxidase subunit I conserved
SMc03140 -1.9 -5.2 transcriptional regulator compare
SMc02484 -1.9 -5.1 amino acid efflux transmembrane protein compare
SMc00361 -1.9 -3.4 hypothetical protein compare
SMc02574 -1.8 -3.6 imidazoleglycerol-phosphate dehydratase compare
SMc02510 -1.8 -1.0 ferric uptake regulation protein compare
SMc01770 -1.8 -2.6 serine hydroxymethyltransferase compare
SMc00602 -1.8 -6.3 excinuclease ABC subunit C compare
SMc01347 -1.8 -3.4 hypothetical protein compare
SMc00522 -1.8 -10.1 ATP-dependent RNA helicase compare
SMc02234 -1.8 -3.4 hypothetical protein compare
SMc01595 -1.8 -2.3 sensor histidine kinase transmembrane protein compare
SMc01187 -1.8 -2.7 rare lipoprotein A compare
SMc01361 -1.7 -4.7 dihydroorotase compare
SMc01280 -1.7 -1.9 protease compare
SMc02115 -1.7 -1.0 hypothetical protein compare
SM_b21524 -1.7 -2.5 septum formation inhibitor compare
SMc02114 -1.6 -3.4 hypothetical protein compare
SMc02495 -1.6 -1.7 translaldolase compare
SMc02077 -1.6 -3.8 exodeoxyribonuclease III protein compare
SMc02309 -1.6 -5.1 arsenate reductase compare
SMc02505 -1.6 -1.9 hypothetical protein compare
SMc02900 -1.6 -3.9 hypothetical protein compare
SMc00981 -1.6 -4.6 ferredoxin protein compare
SMa5033 -1.6 -1.3 hypothetical protein compare
SMc02543 -1.5 -3.6 hypothetical protein compare
SMc02362 -1.5 -2.9 cytochrome c-type biogenesis protein CcmE compare
SMc01438 -1.5 -4.4 protease precursor signal peptide protein compare
SMc01235 -1.5 -9.6 excinuclease ABC subunit A compare
SMc01204 -1.5 -5.9 transmembrane oxidoreductase compare
SMc04383 -1.5 -3.0 putative hydrolase, required for lysine catabolism (from data) compare
SMc00856 -1.5 -1.3 hypothetical protein compare
SMc04024 -1.5 -6.9 membrane-bound lytic murein transglycosylase compare
SMc01260 -1.4 -4.3 transcriptional regulator compare
SMc02141 -1.4 -1.4 phosphate transporter PhoU compare
SMc00937 -1.4 -8.6 TRK system potassium uptake transmembrane protein compare
SMc01461 -1.4 -4.2 DNA helicase II protein compare
SMc02102 -1.4 -3.1 hypothetical protein compare
SMc00026 -1.4 -5.1 hypothetical protein compare
SM_b20948 -1.4 -1.9 glucosyltransferase compare
SMc00296 -1.4 -6.8 POLY3-hydroxybutyrate polymerase compare
SMc02474 -1.4 -3.1 ABC transporter ATP-binding protein compare
SMc00982 -1.4 -5.7 dioxygenase compare
SMc01220 -1.4 -5.1 lipopolysaccharide core biosynthesis glycosyl transferase compare
SM_b21487 -1.3 -7.1 cytochrome o ubiquinol oxidase subunit II conserved
SMc00514 -1.3 -3.8 monooxygenase compare
SM_b21210 -1.3 -2.4 two-component response regulator protein compare
SMc00987 -1.3 -3.0 hypothetical protein compare
SMc03849 -1.3 -1.3 heme exporter C (cytochrome C-type biogenesis protein) transmembrane compare
SMc02050 -1.3 -2.7 trigger factor compare
SMc00726 -1.3 -0.9 thiol:disulfide interchange redox-active center transmembrane protein compare
SM_b21523 -1.3 -1.9 cell division inhibitor protein compare
SMc00404 -1.2 -0.9 hypothetical protein compare
SM_b20595 -1.2 -3.3 cell division protein FtsK compare
SM_b21175 -1.2 -4.6 phosphate uptake ABC transporter permease compare
SM_b20017 -1.2 -5.1 sugar ABC transporter ATP-binding protein compare
SMc01127 -1.2 -4.0 hypothetical protein compare
SMc00760 -1.2 -3.9 recombinase A compare
SMc00298 -1.2 -3.3 methionine aminopeptidase compare
SMc00295 -1.2 -1.3 hypothetical protein compare
SMc00970 -1.2 -2.4 exodeoxyribonuclease VII small subunit compare
SMc00461 -1.2 -1.7 deoxyuridine 5'-triphosphate nucleotidohydrolase compare
SM_b20701 -1.2 -1.0 hypothetical protein compare
SM_b20953 -1.2 -1.1 hypothetical protein compare
SMc01114 -1.2 -4.0 phoH-like protein compare
SMc01360 -1.2 -2.9 aspartate carbamoyltransferase catalytic subunit compare
SMc01116 -1.2 -4.0 acyltransferase transmembrane protein compare
SMc03289 -1.1 -1.3 hypothetical protein compare
SMc02737 -1.1 -4.1 glycine betaine-binding ABC transporter protein compare
SMa1239 -1.1 -1.8 NapD component of periplasmic nitrate reductase compare
SMa1201 -1.1 -2.0 hypothetical protein compare
SMc02071 -1.1 -2.8 hydrolase glycosidase compare
SMa1240 -1.1 -1.0 NapF ferredoxin component of periplasmic nitrate reductase compare
SM_b21213 -1.1 -2.7 serinethreonine protein phosphatase compare
SMc01569 -1.1 -1.4 carbamoyl phosphate synthase small subunit compare
SMc03091 -1.1 -3.8 arginase compare
SMc01606 -1.1 -6.0 permease compare
SM_b20015 -1.1 -5.2 sugar ABC transporter permease compare
SMc00948 -1.1 -6.2 glutamine synthetase compare
SMa1118 -1.1 -1.3 HspC2 heat shock protein compare
SMc04121 -1.0 -1.3 uracil phosphoribosyltransferase compare
SMc00556 -1.0 -3.7 DNA repair protein RadA compare
SM_b20452 -1.0 -1.9 hypothetical protein compare
SMc01605 -1.0 -4.9 periplasmic binding ABC transporter protein compare
SMc00060 -1.0 -5.2 hypothetical protein compare
SMc00247 -1.0 -5.4 phosphatidylcholine synthase compare
SM_b20042 -1.0 -3.3 hypothetical protein compare
SMa2253 -1.0 -1.5 hypothetical protein compare
SMc02989 -1.0 -1.2 hypothetical protein compare
SMc01575 -1.0 -6.2 hypothetical protein compare
SMc00691 -1.0 -3.7 site-specific tyrosine recombinase XerD compare
SMc02407 -1.0 -3.2 hypothetical protein compare
SMc00576 -1.0 -1.7 hypothetical protein compare
SMc02755 -1.0 -3.2 S-adenosyl-L-homocysteine hydrolase compare
SMc04231 -1.0 -4.2 excinuclease ABC subunit B compare
SMc02451 -1.0 -1.6 hypothetical protein compare
SMc01607 -1.0 -5.8 permease compare
SMa0886 -0.9 -1.4 hypothetical protein compare
SMc02403 -0.9 -6.9 murein transglycosylase compare
SMc03826 -0.9 -1.7 argininosuccinate synthase compare
SMa1933 -0.9 -2.1 LysR family transcriptional regulator compare
SM_b21174 -0.9 -3.1 phosphate uptake ABC transporter permease compare
SMc00321 -0.9 -3.8 tRNA pseudouridine synthase B compare
SMc01215 -0.9 -2.9 carbamoyl phosphate synthase large subunit compare
SMc02573 -0.9 -1.4 hypothetical protein compare
SM_b20450 -0.9 -5.7 regulatory protein compare
SMa0882 -0.9 -1.2 hypothetical protein compare
SMc00928 -0.9 -0.7 signal peptide protein compare
SMc00689 -0.9 -3.1 lipoprotein compare
SMc00088 -0.9 -1.0 hypothetical protein compare
SMc00675 -0.9 -6.1 hypothetical protein compare
SMc02739 -0.9 -2.4 glycine betaine transport ATP-binding ABC transporter protein compare
SMc00347 -0.9 -1.8 nucleoside diphosphate kinase regulator compare
SMc01608 -0.9 -3.1 ABC transporter ATP-binding protein compare
SMc03878 -0.9 -1.4 acetoacetyl-CoA reductase compare
SMc01447 -0.9 -1.0 hypothetical protein compare
SMc02266 -0.9 -1.5 hypothetical protein compare
SMc02165 -0.8 -4.5 orotate phosphoribosyltransferase compare
SMc03128 -0.8 -2.0 ABC transporter permease compare
SMc02901 -0.8 -0.7 hypothetical protein compare
SMc00470 -0.8 -1.7 hypothetical protein compare
SMc03850 -0.8 -1.0 heme exporter D (cytochrome C-type biogenesis protein) transmembrane compare
SM_b20387 -0.8 -0.8 transcriptional regulator compare
SM_b20616 -0.8 -1.3 thiamine biosynthesis oxidoreductase compare
SMc04330 -0.8 -1.3 trimethylamine methyltransferase compare
SMc00941 -0.8 -1.0 hypothetical protein compare
SMc01472 -0.8 -0.6 50S ribosomal protein L11 methyltransferase compare
SMc02232 -0.8 -2.5 hypothetical protein compare
SM_b20209 -0.8 -2.7 hypothetical protein compare
SMc01877 -0.8 -3.1 DNA repair protein compare
SM_b20655 -0.8 -1.6 hypothetical protein compare
SMc02435 -0.8 -1.9 methyltransferase compare
SM_b21173 -0.8 -1.3 hypothetical protein compare
SMc02979 -0.8 -2.9 hypothetical protein compare
SMc02738 -0.8 -3.5 glycine betaine transport system permease ABC transporter protein compare
SMc01853 -0.8 -1.5 hypothetical protein compare
SMc01342 -0.8 -3.0 hypothetical protein compare
SMc00073 -0.8 -1.7 hypothetical protein compare
SMc00166 -0.8 -1.3 oxidoreductase NAD protein compare


Specific Phenotypes

For 6 genes in this experiment

For stress copper (II) chloride dihydrate in Sinorhizobium meliloti 1021

For stress copper (II) chloride dihydrate across organisms