Experiment set1IT039 for Pseudomonas fluorescens FW300-N1B4

Compare to:

LB with copper (II) chloride dihydrate 2.5 mM

200 most important genes:

  gene name fitness t score description  
Pf1N1B4_68 -3.8 -2.6 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) compare
Pf1N1B4_2291 -3.2 -9.6 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) conserved
Pf1N1B4_1262 -2.8 -7.3 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf1N1B4_2106 -2.6 -4.2 Hydrogen peroxide-inducible genes activator compare
Pf1N1B4_3246 -2.5 -4.6 RND efflux system, inner membrane transporter CmeB compare
Pf1N1B4_2682 -2.1 -2.7 Antiholin-like protein LrgA compare
Pf1N1B4_4393 -1.8 -2.4 Ferredoxin reductase compare
Pf1N1B4_1263 -1.8 -3.1 Cu(I)-responsive transcriptional regulator compare
Pf1N1B4_4038 -1.8 -2.5 NADH-ubiquinone oxidoreductase chain E (EC 1.6.5.3) compare
Pf1N1B4_208 -1.8 -4.0 Two-component system response regulator QseB compare
Pf1N1B4_1624 -1.7 -7.5 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf1N1B4_4728 -1.7 -5.2 Na+/H+ antiporter NhaB compare
Pf1N1B4_2102 -1.6 -1.9 hypothetical protein compare
Pf1N1B4_32 -1.6 -3.2 Transcriptional regulator, TetR family compare
Pf1N1B4_2290 -1.6 -3.3 Cd(II)/Pb(II)-responsive transcriptional regulator compare
Pf1N1B4_1626 -1.6 -6.2 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf1N1B4_66 -1.6 -4.9 Copper tolerance protein compare
Pf1N1B4_1554 -1.6 -5.7 predicted FeS cluster maintenance protein (from data) compare
Pf1N1B4_4612 -1.5 -2.9 FIG00954117: hypothetical protein compare
Pf1N1B4_1403 -1.5 -6.2 3'-to-5' exoribonuclease RNase R compare
Pf1N1B4_2177 -1.5 -1.3 FIG00953342: hypothetical protein compare
Pf1N1B4_683 -1.5 -3.2 Fumarate hydratase class I, aerobic (EC 4.2.1.2) compare
Pf1N1B4_4835 -1.5 -2.1 Carbon starvation protein A compare
Pf1N1B4_1565 -1.4 -3.4 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf1N1B4_1057 -1.4 -2.2 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf1N1B4_1627 -1.4 -3.8 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf1N1B4_197 -1.4 -1.9 FIG139991: Putative thiamine pyrophosphate-requiring enzyme compare
Pf1N1B4_769 -1.4 -5.3 Aerobic glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) compare
Pf1N1B4_5014 -1.4 -2.6 Glutathione reductase (EC 1.8.1.7) compare
Pf1N1B4_3531 -1.4 -2.6 FIG039061: hypothetical protein related to heme utilization compare
Pf1N1B4_2145 -1.4 -1.5 Translation initiation inhibitor compare
Pf1N1B4_1679 -1.4 -1.5 Membrane-fusion protein compare
Pf1N1B4_1667 -1.4 -2.3 Histone acetyltransferase HPA2 and related acetyltransferases compare
Pf1N1B4_3927 -1.3 -1.7 hypothetical protein compare
Pf1N1B4_1408 -1.3 -3.7 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf1N1B4_1159 -1.3 -2.9 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
Pf1N1B4_5043 -1.3 -2.7 hypothetical protein compare
Pf1N1B4_5823 -1.3 -1.7 Na(+) H(+) antiporter subunit C compare
Pf1N1B4_4446 -1.3 -1.8 DNA topoisomerase III (EC 5.99.1.2) compare
Pf1N1B4_3906 -1.3 -2.4 DNA topoisomerase I (EC 5.99.1.2) compare
Pf1N1B4_5059 -1.2 -2.3 Transcriptional regulator, LysR family compare
Pf1N1B4_4040 -1.2 -2.6 NADH-ubiquinone oxidoreductase chain B (EC 1.6.5.3) compare
Pf1N1B4_5340 -1.2 -1.9 hypothetical protein compare
Pf1N1B4_4295 -1.2 -2.7 FIG00954434: hypothetical protein compare
Pf1N1B4_4419 -1.2 -2.0 Organosulfonate utilization protein SsuF compare
Pf1N1B4_4974 -1.2 -2.7 Protease subunit of ATP-dependent Clp proteases compare
Pf1N1B4_616 -1.2 -2.6 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf1N1B4_3350 -1.1 -2.1 FIG00954807: hypothetical protein compare
Pf1N1B4_3356 -1.1 -1.6 Cyclic nucleotide-binding protein compare
Pf1N1B4_4866 -1.1 -2.2 hypothetical protein compare
Pf1N1B4_2377 -1.1 -4.6 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf1N1B4_5645 -1.1 -2.6 Glutamine ABC transporter, periplasmic glutamine-binding protein (TC 3.A.1.3.2) compare
Pf1N1B4_2707 -1.1 -3.1 Putative membrane protein compare
Pf1N1B4_3025 -1.1 -3.1 Spermidine Putrescine ABC transporter permease component potC (TC_3.A.1.11.1) compare
Pf1N1B4_5420 -1.1 -2.0 hypothetical protein compare
Pf1N1B4_2282 -1.1 -5.5 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf1N1B4_44 -1.1 -6.5 Multicopper oxidase conserved
Pf1N1B4_3833 -1.1 -5.2 Major porin and structural outer membrane porin OprF compare
Pf1N1B4_1067 -1.1 -4.2 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf1N1B4_5146 -1.1 -1.8 Chromosome initiation inhibitor compare
Pf1N1B4_211 -1.1 -7.4 Cytochrome c-type biogenesis protein CcmG/DsbE, thiol:disulfide oxidoreductase compare
Pf1N1B4_5275 -1.1 -2.0 hypothetical protein compare
Pf1N1B4_1812 -1.1 -2.5 Iron siderophore sensor protein compare
Pf1N1B4_1617 -1.1 -4.8 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (EC 5.4.2.1) compare
Pf1N1B4_2894 -1.0 -2.8 FIG00956317: hypothetical protein compare
Pf1N1B4_3998 -1.0 -3.1 putative exported protein compare
Pf1N1B4_4993 -1.0 -2.8 Arabinose efflux permease compare
Pf1N1B4_2090 -1.0 -2.5 FIG00959590: hypothetical protein compare
Pf1N1B4_3297 -1.0 -3.2 Ribosomal small subunit pseudouridine synthase A (EC 4.2.1.70) compare
Pf1N1B4_3636 -1.0 -2.2 FIG00953562: hypothetical protein compare
Pf1N1B4_644 -1.0 -1.5 Cold shock protein CspC compare
Pf1N1B4_2224 -1.0 -1.8 FIG00953390: hypothetical protein compare
Pf1N1B4_1236 -1.0 -4.3 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf1N1B4_4100 -1.0 -1.4 probable transmembrane protein compare
Pf1N1B4_2850 -1.0 -4.9 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf1N1B4_1830 -1.0 -4.9 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf1N1B4_5255 -1.0 -1.9 hypothetical protein compare
Pf1N1B4_5668 -1.0 -1.6 Peptidase, U7 family compare
Pf1N1B4_45 -1.0 -3.8 Copper resistance protein B compare
Pf1N1B4_103 -1.0 -3.3 Histidine permease YuiF compare
Pf1N1B4_539 -1.0 -1.8 Transcriptional regulators compare
Pf1N1B4_1844 -1.0 -6.5 Oligopeptidase A (EC 3.4.24.70) compare
Pf1N1B4_5051 -1.0 -1.8 Sensor protein DegS compare
Pf1N1B4_3328 -1.0 -1.4 Rhodanese-like domain protein compare
Pf1N1B4_1317 -1.0 -2.0 Sensor histidine kinase/response regulator compare
Pf1N1B4_1227 -1.0 -2.2 FIG00954870: hypothetical protein compare
Pf1N1B4_2695 -0.9 -1.6 Rare lipoprotein A precursor compare
Pf1N1B4_4810 -0.9 -1.7 Polymyxin resistance protein PmrM compare
Pf1N1B4_3750 -0.9 -2.3 Potassium efflux system KefA protein / Small-conductance mechanosensitive channel compare
Pf1N1B4_4119 -0.9 -1.7 dioxygenase compare
Pf1N1B4_1837 -0.9 -1.2 Osmotically inducible protein C compare
Pf1N1B4_2958 -0.9 -1.3 Medium-chain-fatty-acid--CoA ligase (EC 6.2.1.-) compare
Pf1N1B4_3647 -0.9 -5.7 Cytochrome c heme lyase subunit CcmH compare
Pf1N1B4_1462 -0.9 -6.3 Oligosaccharide repeat unit polymerase Wzy; O-antigen ligase compare
Pf1N1B4_3656 -0.9 -1.5 Eukaryotic-type low-affinity urea transporter compare
Pf1N1B4_228 -0.9 -2.1 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 compare
Pf1N1B4_4041 -0.9 -2.4 NADH ubiquinone oxidoreductase chain A (EC 1.6.5.3) compare
Pf1N1B4_1676 -0.9 -2.9 Inner membrane component of tripartite multidrug resistance system compare
Pf1N1B4_3396 -0.9 -1.5 Protein export cytoplasm protein SecA ATPase RNA helicase (TC 3.A.5.1.1) compare
Pf1N1B4_2464 -0.9 -1.9 Ribosomal protein S6 glutaminyl transferase compare
Pf1N1B4_2621 -0.9 -1.4 PspA/IM30 family protein compare
Pf1N1B4_3866 -0.9 -1.7 Adenine phosphoribosyltransferase (EC 2.4.2.7) compare
Pf1N1B4_2949 -0.9 -1.8 FIG00956396: hypothetical protein compare
Pf1N1B4_1375 -0.9 -5.4 Mannose-6-phosphate isomerase (EC 5.3.1.8) compare
Pf1N1B4_4487 -0.9 -1.7 FIG00955631: hypothetical protein compare
Pf1N1B4_2684 -0.9 -1.4 Uncharacterized protein, similar to the N-terminal domain of Lon protease compare
Pf1N1B4_1388 -0.9 -2.2 Azurin compare
Pf1N1B4_2490 -0.9 -3.5 Biotin synthesis protein BioC compare
Pf1N1B4_4408 -0.9 -2.1 two-component response regulator compare
Pf1N1B4_5898 -0.9 -1.9 hypothetical protein compare
Pf1N1B4_5072 -0.9 -1.8 Glycerol-3-phosphate regulon repressor compare
Pf1N1B4_3665 -0.9 -2.2 Transcriptional regulator, TetR family compare
Pf1N1B4_5904 -0.9 -1.7 FIG00955320: hypothetical protein compare
Pf1N1B4_2054 -0.9 -2.0 FIG00964469: hypothetical protein compare
Pf1N1B4_210 -0.9 -4.8 Cytochrome c-type biogenesis protein DsbD, protein-disulfide reductase (EC 1.8.1.8) compare
Pf1N1B4_2331 -0.9 -3.2 Thiazole biosynthesis protein ThiG compare
Pf1N1B4_1001 -0.8 -4.6 Outer membrane component of tripartite multidrug resistance system compare
Pf1N1B4_2214 -0.8 -2.1 Transcriptional regulator, GntR family compare
Pf1N1B4_5618 -0.8 -2.1 Excinuclease ABC subunit C compare
Pf1N1B4_2379 -0.8 -4.6 Surface antigen gene compare
Pf1N1B4_3093 -0.8 -1.6 Outer membrane protein H precursor compare
Pf1N1B4_4280 -0.8 -2.3 Myo-inositol 2-dehydrogenase (EC 1.1.1.18) compare
Pf1N1B4_1508 -0.8 -1.7 Lysophospholipid acyltransferase compare
Pf1N1B4_1749 -0.8 -1.3 Prevent host death protein, Phd antitoxin compare
Pf1N1B4_2487 -0.8 -4.1 Biotin synthase (EC 2.8.1.6) compare
Pf1N1B4_2549 -0.8 -4.6 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf1N1B4_688 -0.8 -1.6 FIG00955483: hypothetical protein compare
Pf1N1B4_1276 -0.8 -1.6 Flp pilus assembly protein RcpC/CpaB compare
Pf1N1B4_974 -0.8 -2.0 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf1N1B4_4979 -0.8 -1.9 Transcriptional regulator, AsnC family compare
Pf1N1B4_1474 -0.8 -2.9 Glutamate-ammonia-ligase adenylyltransferase (EC 2.7.7.42) compare
Pf1N1B4_1874 -0.8 -2.0 FIG00953549: hypothetical protein compare
Pf1N1B4_3722 -0.8 -2.2 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf1N1B4_2105 -0.8 -1.5 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf1N1B4_538 -0.8 -1.7 hypothetical protein compare
Pf1N1B4_2884 -0.8 -2.8 Paraquat-inducible protein A compare
Pf1N1B4_2820 -0.8 -2.1 FIG00953647: hypothetical protein compare
Pf1N1B4_2094 -0.8 -2.2 Outer membrane protein ImpK/VasF, OmpA/MotB domain compare
Pf1N1B4_1946 -0.8 -2.8 Transcriptional regulator of glmS gene, DeoR family compare
Pf1N1B4_5607 -0.8 -2.2 C4-dicarboxylate transport protein compare
Pf1N1B4_1831 -0.8 -5.2 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf1N1B4_441 -0.8 -1.7 hypothetical protein compare
Pf1N1B4_3684 -0.8 -3.1 Succinyl-CoA ligase [ADP-forming] beta chain (EC 6.2.1.5) compare
Pf1N1B4_5598 -0.8 -1.4 hypothetical protein compare
Pf1N1B4_3525 -0.8 -1.2 hydrolase, alpha/beta fold family compare
Pf1N1B4_5838 -0.8 -1.5 FIG00956589: hypothetical protein compare
Pf1N1B4_4603 -0.8 -1.7 hypothetical protein compare
Pf1N1B4_3876 -0.8 -4.1 Cytochrome c oxidase subunit CcoP (EC 1.9.3.1) compare
Pf1N1B4_4715 -0.8 -1.4 Transcriptional regulator compare
Pf1N1B4_1430 -0.8 -1.7 Predicted signal transduction protein compare
Pf1N1B4_4336 -0.8 -1.9 FMN-dependent NADH-azoreductase compare
Pf1N1B4_4874 -0.8 -1.4 hypothetical protein compare
Pf1N1B4_652 -0.8 -4.5 Sensory box histidine kinase compare
Pf1N1B4_1975 -0.8 -1.8 Transcriptional regulator, AsnC family compare
Pf1N1B4_1054 -0.8 -2.3 Phosphate acetyltransferase (EC 2.3.1.8) compare
Pf1N1B4_5266 -0.8 -1.4 hypothetical protein compare
Pf1N1B4_5269 -0.8 -1.7 hypothetical protein compare
Pf1N1B4_131 -0.8 -1.8 hypothetical protein compare
Pf1N1B4_4517 -0.8 -1.8 Dihydropyrimidinase (EC 3.5.2.2) compare
Pf1N1B4_4139 -0.8 -1.2 Transcriptional regulator, MerR family compare
Pf1N1B4_5512 -0.8 -1.4 hypothetical protein compare
Pf1N1B4_2948 -0.8 -1.2 FIG00954698: hypothetical protein compare
Pf1N1B4_3612 -0.8 -1.8 Flagellar hook-length control protein FliK compare
Pf1N1B4_2885 -0.8 -3.2 Paraquat-inducible protein A compare
Pf1N1B4_3879 -0.8 -5.6 Cytochrome c oxidase subunit CcoN (EC 1.9.3.1) compare
Pf1N1B4_2465 -0.8 -1.5 Two-component response regulator CreB compare
Pf1N1B4_618 -0.8 -2.7 Acetyl-CoA carboxylase alpha subunit compare
Pf1N1B4_1212 -0.7 -2.0 Predicted flavin reductase RutF in novel pyrimidine catabolism pathway compare
Pf1N1B4_4030 -0.7 -1.3 NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3) compare
Pf1N1B4_1703 -0.7 -1.7 Methionine ABC transporter permease protein compare
Pf1N1B4_4381 -0.7 -1.2 Transcriptional regulator, LysR family compare
Pf1N1B4_5282 -0.7 -1.5 Phage protein compare
Pf1N1B4_2210 -0.7 -1.0 Glutamate transport ATP-binding protein compare
Pf1N1B4_5430 -0.7 -1.7 hypothetical protein compare
Pf1N1B4_1307 -0.7 -1.2 3-dehydroquinate dehydratase II (EC 4.2.1.10) compare
Pf1N1B4_372 -0.7 -1.7 UDP-galactose-lipid carrier transferase (EC 2.-.-.-) compare
Pf1N1B4_544 -0.7 -1.6 Small-conductance mechanosensitive channel compare
Pf1N1B4_3143 -0.7 -1.9 RecA protein compare
Pf1N1B4_5995 -0.7 -1.3 Transporter, MFS superfamily compare
Pf1N1B4_479 -0.7 -1.8 Butyryl-CoA dehydrogenase (EC 1.3.99.2) compare
Pf1N1B4_4601 -0.7 -1.8 Streptothricin acetyltransferase, Streptomyces lavendulae type compare
Pf1N1B4_1180 -0.7 -1.2 Outer membrane lipoprotein SmpA, a component of the essential YaeT outer-membrane protein assembly complex compare
Pf1N1B4_3222 -0.7 -1.3 Ferredoxin compare
Pf1N1B4_2488 -0.7 -3.7 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf1N1B4_1573 -0.7 -2.6 Glucans biosynthesis protein G precursor compare
Pf1N1B4_1827 -0.7 -2.3 FIG00953482: hypothetical protein compare
Pf1N1B4_5815 -0.7 -2.0 diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) compare
Pf1N1B4_5976 -0.7 -1.3 1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) compare
Pf1N1B4_5342 -0.7 -1.1 hypothetical protein compare
Pf1N1B4_1178 -0.7 -2.9 DNA repair protein RecN compare
Pf1N1B4_489 -0.7 -2.9 hypothetical protein possibly connected to lactam utilization and allophanate hydrolase compare
Pf1N1B4_2234 -0.7 -2.4 Aminomethyltransferase (glycine cleavage system T protein) (EC 2.1.2.10) compare
Pf1N1B4_5619 -0.7 -2.5 BarA-associated response regulator UvrY (= GacA = SirA) compare
Pf1N1B4_2322 -0.7 -1.6 FIG015547: peptidase, M16 family compare
Pf1N1B4_2173 -0.7 -1.1 Diaminopimelate epimerase (EC 5.1.1.7) compare
Pf1N1B4_3339 -0.7 -2.1 Transcriptional regulator, LysR family compare
Pf1N1B4_1110 -0.7 -2.4 5-dehydro-4-deoxyglucarate dehydratase (EC 4.2.1.41) (from data) compare
Pf1N1B4_3410 -0.7 -2.5 FIG00964654: hypothetical protein compare
Pf1N1B4_4887 -0.7 -1.3 Pirin compare
Pf1N1B4_886 -0.7 -1.4 FIG137478: Hypothetical protein compare


Specific Phenotypes

For 4 genes in this experiment

For stress copper (II) chloride dihydrate in Pseudomonas fluorescens FW300-N1B4

For stress copper (II) chloride dihydrate across organisms