Experiment set1IT039 for Pseudomonas fluorescens FW300-N1B4

Compare to:

LB with copper (II) chloride dihydrate 2.5 mM

200 most detrimental genes:

  gene name fitness t score description  
Pf1N1B4_2381 +1.9 11.3 Protein yceI precursor compare
Pf1N1B4_2380 +1.8 10.8 Cytochrome B561 compare
Pf1N1B4_3454 +1.6 9.0 Mg/Co/Ni transporter MgtE / CBS domain compare
Pf1N1B4_5925 +1.5 8.3 hypothetical protein compare
Pf1N1B4_5926 +1.4 7.9 hypothetical protein compare
Pf1N1B4_507 +1.4 1.7 FIG00956448: hypothetical protein compare
Pf1N1B4_5483 +1.3 2.3 hypothetical protein compare
Pf1N1B4_5331 +1.2 3.1 hypothetical protein compare
Pf1N1B4_4509 +1.2 2.7 Aldose 1-epimerase compare
Pf1N1B4_263 +1.1 3.8 Thiopurine S-methyltransferase (EC 2.1.1.67) compare
Pf1N1B4_483 +1.1 2.5 Metal-dependent hydrolase related to alanyl-tRNA synthetase compare
Pf1N1B4_5924 +1.1 7.2 hypothetical protein compare
Pf1N1B4_114 +1.1 2.3 Diaminopimelate epimerase (EC 5.1.1.7) compare
Pf1N1B4_1457 +1.0 5.8 Hypothetical protein FIG015671 in large core OS assembly cluster compare
Pf1N1B4_3751 +0.9 1.4 FIG00953060: hypothetical protein compare
Pf1N1B4_4422 +0.9 1.9 ABC transporter amino acid-binding protein compare
Pf1N1B4_5242 +0.9 2.0 hypothetical protein compare
Pf1N1B4_3408 +0.9 2.0 Transcriptional regulator, AraC family compare
Pf1N1B4_3582 +0.9 1.7 C-methyltransferase compare
Pf1N1B4_2060 +0.9 2.4 hypothetical protein compare
Pf1N1B4_4860 +0.9 2.8 Sensory box sensor histidine kinase/response regulator (EC 2.7.3.-) compare
Pf1N1B4_4505 +0.9 2.6 Coenzyme PQQ synthesis protein E compare
Pf1N1B4_3468 +0.9 1.5 Negative regulator of flagellin synthesis FlgM compare
Pf1N1B4_1456 +0.8 5.7 Hypothetical protein FIG015671 in large core OS assembly cluster compare
Pf1N1B4_2005 +0.8 1.5 ATP-dependent DNA helicase UvrD/PcrA compare
Pf1N1B4_4256 +0.8 2.7 Probable transmembrane protein compare
Pf1N1B4_3437 +0.8 4.5 Arginine pathway regulatory protein ArgR, repressor of arg regulon compare
Pf1N1B4_1527 +0.8 2.9 Queuosine Biosynthesis QueC ATPase compare
Pf1N1B4_4458 +0.8 2.9 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) compare
Pf1N1B4_1754 +0.8 2.8 Putative stomatin/prohibitin-family membrane protease subunit aq_911 compare
Pf1N1B4_615 +0.8 2.2 Arginine deiminase (EC 3.5.3.6) compare
Pf1N1B4_2858 +0.8 6.2 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf1N1B4_3492 +0.8 2.6 DNA-3-methyladenine glycosylase (EC 3.2.2.20) compare
Pf1N1B4_1331 +0.8 2.6 Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-) compare
Pf1N1B4_3519 +0.8 2.7 Lipase (EC 3.1.1.3) compare
Pf1N1B4_756 +0.8 1.7 hypothetical protein compare
Pf1N1B4_855 +0.8 2.1 FIG021952: putative membrane protein compare
Pf1N1B4_2287 +0.7 3.5 Protein of unknown function DUF81 compare
Pf1N1B4_823 +0.7 1.5 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf1N1B4_2435 +0.7 1.4 hypothetical protein compare
Pf1N1B4_4776 +0.7 2.7 Nicotinamidase (EC 3.5.1.19) compare
Pf1N1B4_3785 +0.7 1.9 FOG: Ankyrin repeat compare
Pf1N1B4_1458 +0.7 4.1 Probable transcription regulator Mig-14 compare
Pf1N1B4_4922 +0.7 3.9 Opine oxidase subunit B compare
Pf1N1B4_3176 +0.7 2.8 Succinylglutamate desuccinylase/aspartoacylase compare
Pf1N1B4_695 +0.7 2.0 Aldehyde dehydrogenase (EC 1.2.1.3) compare
Pf1N1B4_619 +0.7 1.6 Sigma-54 dependent transcriptional regulator/sensory box protein compare
Pf1N1B4_4132 +0.7 1.5 Mobile element protein compare
Pf1N1B4_3936 +0.7 1.8 Transcriptional regulator, LysR family compare
Pf1N1B4_6030 +0.7 1.9 Ribose ABC transport system, high affinity permease RbsD (TC 3.A.1.2.1) compare
Pf1N1B4_980 +0.7 1.6 hypothetical protein compare
Pf1N1B4_4478 +0.7 1.8 Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.168) compare
Pf1N1B4_2227 +0.7 1.6 FIG019278: hypothetical protein compare
Pf1N1B4_1916 +0.7 1.7 Chaperone protein YscY (Yop proteins translocation protein Y) compare
Pf1N1B4_2075 +0.7 1.6 ABC-type antimicrobial peptide transport system, permease component compare
Pf1N1B4_3504 +0.7 2.2 Two-component sensor histidine kinase PfeS, enterobactin compare
Pf1N1B4_2859 +0.7 6.0 Two-component sensor CbrA: intrcellular carbon:nitrogen balance compare
Pf1N1B4_2232 +0.7 3.2 Ferric iron ABC transporter, iron-binding protein compare
Pf1N1B4_1870 +0.7 1.4 Zinc ABC transporter, ATP-binding protein ZnuC compare
Pf1N1B4_3588 +0.7 1.7 N-Acetylneuraminate cytidylyltransferase (EC 2.7.7.43) compare
Pf1N1B4_4429 +0.7 1.7 No significant database matches compare
Pf1N1B4_5568 +0.7 2.2 hypothetical protein compare
Pf1N1B4_5356 +0.7 2.8 hypothetical protein compare
Pf1N1B4_2510 +0.7 2.5 hypothetical protein compare
Pf1N1B4_2427 +0.7 1.7 Gamma-butyrobetaine,2-oxoglutarate dioxygenase (EC 1.14.11.1) compare
Pf1N1B4_3316 +0.7 2.2 Tricarboxylate transport transcriptional regulator TctD compare
Pf1N1B4_4246 +0.7 2.6 L-lactate permease compare
Pf1N1B4_1052 +0.7 1.8 FKBP-type peptidyl-prolyl cis-trans isomerase SlyD (EC 5.2.1.8) compare
Pf1N1B4_92 +0.7 1.8 Porphobilinogen synthase (EC 4.2.1.24) compare
Pf1N1B4_3900 +0.7 2.3 Universal stress protein family COG0589 compare
Pf1N1B4_1535 +0.7 2.0 hypothetical protein compare
Pf1N1B4_29 +0.7 1.7 FIG00967200: hypothetical protein compare
Pf1N1B4_6045 +0.7 1.8 CigR (Putative inner membrane protein) compare
Pf1N1B4_1093 +0.7 2.7 FIG003879: Predicted amidohydrolase / Omega amidase (Nit2 homolog) compare
Pf1N1B4_648 +0.7 6.1 Outer membrane porin, OprD family compare
Pf1N1B4_3149 +0.6 1.8 hypothetical protein compare
Pf1N1B4_5292 +0.6 1.4 hypothetical protein compare
Pf1N1B4_5611 +0.6 1.8 L-carnitine dehydratase/bile acid-inducible protein F (EC 2.8.3.16) compare
Pf1N1B4_3630 +0.6 1.7 Chemotaxis response regulator protein-glutamate methylesterase CheB (EC 3.1.1.61) compare
Pf1N1B4_3794 +0.6 1.6 hypothetical protein compare
Pf1N1B4_198 +0.6 1.8 FIG137877: Hypothetical protein in pyoverdin gene cluster compare
Pf1N1B4_825 +0.6 1.5 tRNA (uridine-5-oxyacetic acid methyl ester) 34 synthase compare
Pf1N1B4_563 +0.6 1.4 RNA polymerase sigma-70 factor compare
Pf1N1B4_4522 +0.6 2.2 4-carboxymuconolactone decarboxylase domain/alkylhydroperoxidase AhpD family core domain protein compare
Pf1N1B4_1346 +0.6 1.8 Urea ABC transporter, ATPase protein UrtD compare
Pf1N1B4_4918 +0.6 1.4 Predicted enzyme of the cupin superfamily compare
Pf1N1B4_1608 +0.6 1.3 FIG00956533: hypothetical protein compare
Pf1N1B4_5498 +0.6 1.3 hypothetical protein compare
Pf1N1B4_2360 +0.6 1.5 hypothetical protein compare
Pf1N1B4_5078 +0.6 1.8 Transcriptional regulator PhnF compare
Pf1N1B4_4445 +0.6 1.7 acetyltransferase, GNAT family compare
Pf1N1B4_2975 +0.6 1.3 Peptide methionine sulfoxide reductase MsrB (EC 1.8.4.12) compare
Pf1N1B4_72 +0.6 1.2 Transcriptional regulator, LysR family compare
Pf1N1B4_4438 +0.6 1.4 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) compare
Pf1N1B4_4879 +0.6 1.5 Chromosome segregation ATPases compare
Pf1N1B4_656 +0.6 4.1 Glutamate N-acetyltransferase (EC 2.3.1.35) / N-acetylglutamate synthase (EC 2.3.1.1) compare
Pf1N1B4_5991 +0.6 1.3 Transcriptional regulator, AraC family compare
Pf1N1B4_5519 +0.6 1.7 hypothetical protein compare
Pf1N1B4_4433 +0.6 1.2 FIG035246: DoxX family protein compare
Pf1N1B4_175 +0.6 1.5 sigma-54 dependent transcriptional regulator compare
Pf1N1B4_4756 +0.6 2.4 Magnesium and cobalt transport protein CorA compare
Pf1N1B4_5447 +0.6 1.7 hypothetical protein compare
Pf1N1B4_3925 +0.6 2.7 Putative protease compare
Pf1N1B4_474 +0.6 2.6 FIG00954461: hypothetical protein compare
Pf1N1B4_1282 +0.6 2.0 DNA-binding response regulator, LuxR family compare
Pf1N1B4_260 +0.6 1.8 Peptide methionine sulfoxide reductase MsrB (EC 1.8.4.12) compare
Pf1N1B4_5897 +0.6 2.2 FIG00963512: hypothetical protein compare
Pf1N1B4_3211 +0.6 2.2 Putative signal peptide protein compare
Pf1N1B4_3056 +0.6 2.1 Probable carboxyvinyl-carboxyphosphonate phosphorylmutase (EC 2.7.8.23) compare
Pf1N1B4_3346 +0.6 2.9 Protein YcgL compare
Pf1N1B4_3290 +0.6 1.7 Alternative cytochrome c oxidase polypeptide CoxP (EC 1.9.3.1) compare
Pf1N1B4_3747 +0.6 2.8 FIG00956482: hypothetical protein compare
Pf1N1B4_5699 +0.6 1.3 ABC-type uncharacterized transport system, ATPase component compare
Pf1N1B4_4176 +0.6 1.2 Alcohol dehydrogenase (EC 1.1.1.1) compare
Pf1N1B4_3054 +0.6 1.7 FIG00953063: hypothetical protein compare
Pf1N1B4_4857 +0.6 2.6 Chemotaxis protein methyltransferase CheR (EC 2.1.1.80) compare
Pf1N1B4_3242 +0.6 1.9 GCN5-related N-acetyltransferase compare
Pf1N1B4_3126 +0.6 1.8 Phage tail length tape-measure protein compare
Pf1N1B4_1838 +0.6 1.6 FIG00955509: hypothetical protein compare
Pf1N1B4_4863 +0.6 2.4 Outer membrane protein OprN compare
Pf1N1B4_5560 +0.6 1.2 hypothetical protein compare
Pf1N1B4_5721 +0.6 1.6 Periplasmic protein p19 involved in high-affinity Fe2+ transport compare
Pf1N1B4_339 +0.5 1.5 UDP-glucose 4-epimerase (EC 5.1.3.2) compare
Pf1N1B4_1048 +0.5 2.4 Sulfate transporter, CysZ-type compare
Pf1N1B4_448 +0.5 1.3 Aminodeoxychorismate lyase (EC 4.1.3.38) compare
Pf1N1B4_93 +0.5 1.7 Phenazine biosynthesis protein PhzF like compare
Pf1N1B4_1194 +0.5 1.3 hypothetical protein compare
Pf1N1B4_3291 +0.5 1.6 Putative subunit of Alternative cytochrome c oxidase compare
Pf1N1B4_5623 +0.5 2.5 hypothetical protein compare
Pf1N1B4_4136 +0.5 1.5 hypothetical protein compare
Pf1N1B4_1107 +0.5 1.8 D-galactarate dehydratase (EC 4.2.1.42) compare
Pf1N1B4_4320 +0.5 1.8 Phosphonate ABC transporter permease protein phnE2 (TC 3.A.1.9.1) compare
Pf1N1B4_3432 +0.5 3.3 ABC transporter for L-Arginine and L-Citrulline, permease component 1 (from data) compare
Pf1N1B4_1293 +0.5 1.9 hypothetical protein compare
Pf1N1B4_3959 +0.5 2.1 2-aminoethylphosphonate:pyruvate aminotransferase (EC 2.6.1.37) compare
Pf1N1B4_3263 +0.5 2.4 FIG126011: Hypothetical protein compare
Pf1N1B4_2194 +0.5 2.6 Glutathione-regulated potassium-efflux system ATP-binding protein compare
Pf1N1B4_758 +0.5 1.6 Bacterioferritin compare
Pf1N1B4_4305 +0.5 1.6 PUTATIVE METHYLTRANSFERASE compare
Pf1N1B4_1576 +0.5 2.1 Lipolytic enzyme compare
Pf1N1B4_3199 +0.5 2.3 Ribosomal protein S3 compare
Pf1N1B4_2851 +0.5 1.0 hypothetical protein compare
Pf1N1B4_4812 +0.5 1.6 Site-specific recombinase, phage integrase family compare
Pf1N1B4_1530 +0.5 1.7 LysR family transcriptional regulator YnfL compare
Pf1N1B4_623 +0.5 1.2 Aminomethyltransferase (glycine cleavage system T protein) (EC 2.1.2.10) compare
Pf1N1B4_5135 +0.5 1.5 Transcriptional regulator, TetR family compare
Pf1N1B4_844 +0.5 2.1 Exodeoxyribonuclease VII large subunit (EC 3.1.11.6) compare
Pf1N1B4_3191 +0.5 0.7 FIG00953505: hypothetical protein compare
Pf1N1B4_770 +0.5 1.7 hypothetical protein compare
Pf1N1B4_5296 +0.5 2.4 hypothetical protein compare
Pf1N1B4_876 +0.5 1.8 Magnesium and cobalt efflux protein CorC compare
Pf1N1B4_3020 +0.5 1.9 Single-stranded-DNA-specific exonuclease RecJ (EC 3.1.-.-) compare
Pf1N1B4_4992 +0.5 1.9 Dienelactone hydrolase and related enzymes compare
Pf1N1B4_378 +0.5 1.8 Carbon storage regulator compare
Pf1N1B4_4083 +0.5 1.4 Isochorismatase (EC 3.3.2.1) compare
Pf1N1B4_606 +0.5 1.3 Iron siderophore sensor protein compare
Pf1N1B4_4744 +0.5 1.5 Transcriptional regulator, LysR family compare
Pf1N1B4_5446 +0.5 1.5 hypothetical protein compare
Pf1N1B4_3730 +0.5 1.8 Sodium-dependent transporter compare
Pf1N1B4_1756 +0.5 1.3 Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases compare
Pf1N1B4_308 +0.5 1.7 FIG00956090: hypothetical protein compare
Pf1N1B4_409 +0.5 1.8 ABC transporter for D-galactose/L-arabinose, permease component (from data) compare
Pf1N1B4_932 +0.5 0.7 FIG00963370: hypothetical protein compare
Pf1N1B4_4533 +0.5 1.1 Uncharacterized protein ImpH/VasB compare
Pf1N1B4_1326 +0.5 2.6 Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-3b C17-methyltransferase compare
Pf1N1B4_2348 +0.5 2.4 Uracil phosphoribosyltransferase (EC 2.4.2.9) / Pyrimidine operon regulatory protein PyrR compare
Pf1N1B4_3125 +0.5 2.0 FIG00954242: hypothetical protein compare
Pf1N1B4_4733 +0.5 1.4 Fap system putative outer membrane protein compare
Pf1N1B4_776 +0.5 1.5 Two component, Sigma-54 Specific, central transcriptional regulator of acidic amino acid uptake compare
Pf1N1B4_2833 +0.5 1.7 Benzoate transport protein compare
Pf1N1B4_5588 +0.5 0.9 Transcriptional regulator for ferulate or vanillate catabolism compare
Pf1N1B4_5294 +0.5 1.1 hypothetical protein compare
Pf1N1B4_19 +0.5 2.0 tRNA-dihydrouridine synthase C (EC 1.-.-.-) compare
Pf1N1B4_37 +0.5 2.0 N-hydroxyarylamine O-acetyltransferase (EC 2.3.1.118) compare
Pf1N1B4_2854 +0.5 1.8 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) compare
Pf1N1B4_3975 +0.5 1.1 Transcriptional regulator, IclR family compare
Pf1N1B4_165 +0.5 0.9 FIG00638667: hypothetical protein compare
Pf1N1B4_4047 +0.5 2.3 FIG002903: a protein of unknown function perhaps involved in purine metabolism compare
Pf1N1B4_583 +0.5 1.2 FIG00957748: hypothetical protein compare
Pf1N1B4_2860 +0.5 2.9 FIG00954153: hypothetical protein compare
Pf1N1B4_2759 +0.5 2.3 MFS general substrate transporter compare
Pf1N1B4_5093 +0.5 1.4 Endo-beta-1,3-glucanase compare
Pf1N1B4_3814 +0.5 1.9 Para-aminobenzoate synthase, aminase component (EC 2.6.1.85) compare
Pf1N1B4_3836 +0.5 1.4 Nitrite reductase [NAD(P)H] small subunit (EC 1.7.1.4) compare
Pf1N1B4_5791 +0.5 1.0 hypothetical protein compare
Pf1N1B4_4693 +0.5 2.4 Oxidoreductase compare
Pf1N1B4_485 +0.5 1.6 L-lysine permease compare
Pf1N1B4_614 +0.5 1.6 Arginine/ornithine antiporter ArcD compare
Pf1N1B4_3546 +0.5 0.6 P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein compare
Pf1N1B4_1465 +0.5 3.8 Carbamoyltransferase in large core OS assembly cluster compare
Pf1N1B4_5756 +0.5 1.4 Nitric oxide -responding transcriptional regulator Dnr (Crp/Fnr family) compare
Pf1N1B4_1031 +0.5 2.2 Oxidoreductase, short chain dehydrogenase/reductase family compare
Pf1N1B4_2646 +0.5 1.7 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf1N1B4_2744 +0.5 2.2 Transcriptional regulator, IclR family compare
Pf1N1B4_4432 +0.5 1.8 Dienelactone hydrolase family compare
Pf1N1B4_5989 +0.5 1.3 FIG067310: hypothetical protein compare
Pf1N1B4_4204 +0.5 1.7 FldA protein compare
Pf1N1B4_2825 +0.5 1.2 EF hand domain protein compare
Pf1N1B4_5835 +0.5 1.7 3-ketoacyl-CoA thiolase (EC 2.3.1.16) @ Acetyl-CoA acetyltransferase (EC 2.3.1.9) compare
Pf1N1B4_1636 +0.5 0.5 FIG00954739: hypothetical protein compare


Specific Phenotypes

For 4 genes in this experiment

For stress copper (II) chloride dihydrate in Pseudomonas fluorescens FW300-N1B4

For stress copper (II) chloride dihydrate across organisms