Experiment set1IT039 for Sinorhizobium meliloti 1021

Compare to:

LB with Cobalt chloride hexahydrate 0.16 mM

200 most detrimental genes:

  gene name fitness t score description  
SMc00131 +5.2 43.2 transcriptional regulator compare
SMc03069 +4.5 19.9 6-phosphogluconolactonase compare
SMc03900 +4.0 24.4 cyclic beta-1,2-glucan ABc transporter compare
SMc04382 +3.8 30.7 beta-(1,2)-glucan production associated transmembrane protein compare
SMc00647 +3.7 23.6 ribosomal large subunit pseudouridine synthase compare
SMc02659 +3.7 5.3 GTP pyrophosphokinase (ATP:GTP 3'-pyrophosphotransferase) protein compare
SMc00458 +3.3 28.5 transcriptional regulator compare
SMc01124 +3.1 11.2 PII uridylyl-transferase compare
SMc02112 +3.0 24.1 hypothetical protein compare
SMc00565 +2.9 6.4 50S ribosomal protein L9 compare
SMc02137 +2.8 18.5 ornithine carbamoyltransferase compare
SMc01099 +2.7 7.3 tRNA pseudouridine synthase A compare
SMc02755 +2.7 12.5 S-adenosyl-L-homocysteine hydrolase compare
SMc00150 +2.6 24.6 hypothetical protein compare
SMa2020 +2.6 9.4 Transcriptional regulator compare
SMc03855 +2.6 12.2 hypothetical protein compare
SMc04385 +2.5 11.7 L-2-aminoadipate semialdehyde dehydrogenase (EC 1.2.1.31) (from data) compare
SMc00495 +2.5 8.2 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
SMc01120 +2.5 10.2 hypothetical protein compare
SMc02695 +2.4 16.1 GTP-dependent nucleic acid-binding protein EngD compare
SMc03157 +2.4 16.4 outer membrane lipoprotein transmembrane compare
SMc00349 +2.4 18.6 GTP-binding protein LepA compare
SMc02272 +2.4 19.4 acyl-transferase transferase compare
SMc02503 +2.4 11.1 hypothetical protein compare
SMc04081 +2.4 17.6 glycosyl transferase (sulfolipid biosynthesis) protein compare
SMc02367 +2.3 16.9 sensor histidine kinase transmembrane protein compare
SMc00129 +2.3 13.9 sensor histidine kinase compare
SMc02366 +2.3 18.4 transcriptional regulator compare
SMc02273 +2.3 21.4 fatty acid synthase transmembrane protein compare
SMc00414 +2.3 16.2 hypothetical protein compare
SMc00419 +2.2 10.4 glutathione synthetase compare
SMc03159 +2.2 6.1 ABC transporter ATP-binding protein compare
SMc03826 +2.2 13.0 argininosuccinate synthase compare
SMc01275 +2.2 13.6 ribosomal large subunit pseudouridine synthase C protein compare
SMc00711 +2.2 12.7 cyclohexadienyl dehydrogenase compare
SMc04003 +2.1 6.0 50S ribosomal protein L36 compare
SMc01848 +2.1 12.7 hypothetical protein compare
SMc00321 +2.1 11.5 tRNA pseudouridine synthase B compare
SMc00522 +2.1 16.1 ATP-dependent RNA helicase compare
SMc04094 +2.0 6.4 hypothetical protein compare
SMc02365 +2.0 10.4 protease precursor protein compare
SMc03158 +1.9 7.7 ABC transporter permease compare
SMc03961 +1.9 13.6 sulfolipid (UDP-sulfoquinovose) biosynthesis protein compare
SMc02270 +1.9 17.5 capsular polysaccharide biosynthesis\export transmembrane protein compare
SMc02766 +1.9 15.0 tryptophan synthase subunit beta compare
SMc00171 +1.9 11.6 hypothetical protein compare
SMc02858 +1.8 2.3 chaperone protein DnaJ compare
SMc01439 +1.8 5.9 hypothetical protein compare
SMc02138 +1.8 5.6 acetylornithine transaminase compare
SMc02095 +1.8 12.8 hypothetical protein compare
SMc02765 +1.8 13.9 tryptophan synthase subunit alpha compare
SMc02490 +1.8 9.4 hypothetical protein compare
SMc03111 +1.8 10.4 mannose 6-phosphate isomerase (EC 5.3.1.8) (from data) compare
SMc02309 +1.8 12.0 arsenate reductase compare
SMc01207 +1.8 3.7 S-adenosylmethionine--tRNA ribosyltransferase-isomerase compare
SMc01907 +1.7 12.2 hypothetical protein compare
SMc04383 +1.7 5.7 putative hydrolase, required for lysine catabolism (from data) compare
SMc03863 +1.7 4.1 50S ribosomal protein L19 compare
SMc02504 +1.7 8.8 transcriptional regulator compare
SMc03973 +1.7 12.2 hypothetical protein compare
SMc04235 +1.7 9.5 tRNA-dihydrouridine synthase A compare
SMc02558 +1.7 8.6 hypothetical protein compare
SMc02271 +1.6 11.0 ribitol type dehydrogenase compare
SMc02055 +1.6 3.6 phytoene synthase compare
SMc00727 +1.6 10.7 3-hydroxybutyryl-CoA dehydrogenase compare
SMc04167 +1.6 12.1 histidine-rich transporter transmembrane protein conserved
SMc00482 +1.6 9.3 hypothetical protein compare
SMc00187 +1.6 5.0 ubiquinol-cytochrome C reductase iron-sulfur subunit protein compare
SMc02269 +1.6 9.5 capsular polysaccharide biosynthesis/export protein compare
SMc00761 +1.5 11.0 oxidoreductase compare
SMc00566 +1.5 4.5 hypothetical protein compare
SMc00403 +1.5 7.1 NOL1/NOP2/SUN family signature protein compare
SMc00302 +1.5 5.7 hypothetical protein compare
SMc03963 +1.5 10.4 sulfolipid biosynthesis protein compare
SMc00026 +1.5 9.7 hypothetical protein compare
SMc01089 +1.5 2.9 hypothetical protein compare
SM_b21397 +1.4 1.2 hypothetical protein compare
SMc04000 +1.4 3.3 hypothetical protein compare
SMc01215 +1.4 5.6 carbamoyl phosphate synthase large subunit compare
SMc00009 +1.3 6.5 cytochrome C oxidase subunit II protein compare
SMc00998 +1.3 8.8 signal peptide protein compare
SMc00247 +1.3 8.5 phosphatidylcholine synthase compare
SMc00904 +1.3 7.2 hypothetical protein compare
SM_b20994 +1.3 4.9 hypothetical protein compare
SMc02050 +1.3 4.6 trigger factor compare
SMc01206 +1.3 2.0 queuine tRNA-ribosyltransferase compare
SMc04454 +1.2 8.1 ABC transporter ATP-binding protein compare
SMc03932 +1.2 4.8 sarcosine oxidase subunit delta compare
SMc02478 +1.2 7.2 hypothetical protein compare
SMc02684 +1.2 7.4 hydrolase/peptidase compare
SM_b21265 +1.2 5.5 glycosyltransferase compare
SMc03880 +1.2 7.7 hypothetical protein compare
SMc00320 +1.2 4.3 ribosome-binding factor A compare
SMc03931 +1.2 9.9 sarcosine oxidase subunit alpha compare
SM_b20757 +1.2 7.1 methylmalonyl-CoA mutase compare
SMc02793 +1.2 7.6 hypothetical protein compare
SMc03930 +1.1 1.9 sarcosine oxidase subunit gamma compare
SMc00622 +1.1 7.0 ribonuclease D protein compare
SMc04384 +1.1 3.9 (R)-2-hydroxyglutarate dehydrogenase (EC 1.1.99.39) (from data) compare
SMc02384 +1.1 5.5 glycosyltransferase transmembrane protein compare
SMc03933 +1.1 9.6 sarcosine oxidase subunit B protein compare
SMc01846 +1.1 6.7 hydrolase glycosidase compare
SMc01108 +1.1 3.8 tRNA (guanine-N(7)-)-methyltransferase compare
SM_b21551 +1.1 1.9 hypothetical protein compare
SMc04128 +1.1 7.4 heavy metal transporting ATPase conserved
SMc01273 +1.1 9.6 S-formylglutathione hydrolase compare
SMc01223 +1.1 2.8 transcriptional regulator compare
SMc01222 +1.1 4.1 lipopolysaccharide core biosynthesis glycosyl transferase compare
SMa0833 +1.1 1.8 hypothetical protein compare
SMc01847 +1.0 4.5 methyltransferase compare
SMc02136 +1.0 5.9 Hsp33-like chaperonin compare
SMc00070 +1.0 4.9 signal peptide protein compare
SMc00576 +1.0 2.3 hypothetical protein compare
SMc01024 +1.0 1.9 preprotein translocase subunit SecG compare
SMc04882 +1.0 2.3 transcriptional regulator compare
SM_b20725 +1.0 1.3 hypothetical protein compare
SMc00709 +1.0 4.8 hypothetical protein compare
SMc04002 +1.0 6.4 phosphoribosylaminoimidazole carboxylase ATPase subunit compare
SMc02757 +1.0 3.0 hypothetical protein compare
SMc00719 +1.0 2.8 hypoxanthine-guanine phosphoribosyltransferase compare
SMc01193 +0.9 6.0 hypothetical protein compare
SMa1095 +0.9 1.3 hypothetical protein compare
SMa1921 +0.9 2.3 hypothetical protein compare
SMc00710 +0.9 4.6 histidinol-phosphate aminotransferase compare
SM_b21256 +0.9 6.9 nucleotide sugar oxidase compare
SMc04239 +0.9 2.6 hypothetical protein compare
SMc01885 +0.9 5.6 aminopeptidase P protein compare
SM_b20834 +0.9 6.9 surface saccharide synthesis protein compare
SMc02056 +0.9 3.1 hypothetical protein compare
SM_b21170 +0.9 4.8 guanylate kinase compare
SMc00329 +0.9 2.1 iron response regulator protein compare
SM_b21253 +0.9 6.1 hypothetical protein compare
SMc02554 +0.9 3.9 hypothetical protein compare
SM_b20613 +0.9 5.2 C4-dicarboxylate transport transcriptional regulator compare
SMc02989 +0.9 1.7 hypothetical protein compare
SMc01519 +0.9 2.0 hypothetical protein compare
SMc01131 +0.9 2.6 hypothetical protein compare
SMc01698 +0.9 4.3 oxidoreductase compare
SMc01587 +0.8 1.7 hypothetical protein compare
SMc03781 +0.8 4.0 rRNA large subunit methyltransferase compare
SMc01930 +0.8 2.4 hypothetical protein compare
SMc01272 +0.8 4.3 hypothetical protein compare
SMc02879 +0.8 2.1 hypothetical protein compare
SMc02577 +0.8 5.8 ATP-dependent protease ATP-binding subunit HslU compare
SM_b21252 +0.8 6.7 glycosyltransferase compare
SMc02166 +0.8 6.8 dihydroorotase compare
SMc01153 +0.8 1.4 enoyl-CoA hydratase compare
SMc00648 +0.8 3.9 hypothetical protein compare
SMc00012 +0.8 1.6 cytochrome C oxidase assembly protein compare
SM_b20815 +0.8 2.0 outer membrane protein assembly protein compare
SM_b21264 +0.8 6.1 hypothetical protein compare
SMc01041 +0.8 3.7 NIFR3-like protein compare
SMc01916 +0.8 2.2 signal peptide protein compare
SMc01834 +0.8 2.0 hypothetical protein compare
SMc01139 +0.8 2.4 RNA polymerase factor sigma-54 compare
SMc02058 +0.8 2.4 YAJC protein compare
SM_b20684 +0.8 6.3 hypothetical protein compare
SMc04298 +0.8 1.1 hypothetical protein compare
SMc02575 +0.8 4.9 ATP-dependent protease peptidase subunit compare
SMc04001 +0.8 0.9 phosphoribosylaminoimidazole carboxylase catalytic subunit protein compare
SM_b21491 +0.8 5.5 hypothetical protein compare
SMc00325 +0.8 5.3 hypothetical protein compare
SMc01315 +0.8 1.3 hypothetical protein compare
SMc00827 +0.8 5.8 transport transmembrane protein compare
SMc00539 +0.8 5.5 hypothetical protein compare
SMc02983 +0.8 4.2 ornithine, DAP, or arginine decarboxylase compare
SMa0728 +0.7 2.7 hypothetical protein compare
SM_b21487 +0.7 5.6 cytochrome o ubiquinol oxidase subunit II compare
SMc02844 +0.7 0.9 transcriptional regulator compare
SMc01508 +0.7 1.6 hypothetical protein compare
SMa0357 +0.7 2.8 hypothetical protein compare
SM_b20221 +0.7 2.5 epoxide hydrolase compare
SMc01666 +0.7 3.7 methionine gamma-lyase compare
SMc03037 +0.7 1.5 flagellin A compare
SMc00347 +0.7 2.0 nucleoside diphosphate kinase regulator compare
SMc01404 +0.7 2.3 aspartate racemase compare
SMc01801 +0.7 2.2 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) compare
SM_b20131 +0.7 1.1 oxidoreductase compare
SMc01202 +0.7 4.7 lipoprotein compare
SMc01509 +0.7 2.2 hypothetical protein compare
SM_b21549 +0.7 3.7 sulfurtransferase compare
SMc02767 +0.7 3.3 N-(5'-phosphoribosyl)anthranilate isomerase compare
SMc04166 +0.7 2.2 hypothetical protein compare
SMc01256 +0.7 5.3 L-serine dehydratase compare
SMc00351 +0.7 0.9 hypothetical protein compare
SMa0398 +0.7 1.3 histidinol dehydrogenase compare
SMc01160 +0.7 2.4 hypothetical protein compare
SM_b21266 +0.7 4.3 hypothetical protein compare
SMc00802 +0.7 0.7 hypothetical protein compare
SMa0854 +0.7 1.0 3-ketoacyl-ACP reductase compare
SMc00169 +0.7 5.5 malic enzyme compare
SM_b21485 +0.7 1.5 hypothetical protein compare
SMc02904 +0.7 2.1 hypothetical protein compare
SMc00787 +0.7 3.2 peptide ABC transporter permease compare
SMa1136 +0.7 1.8 hypothetical protein compare
SM_b20819 +0.7 2.2 ferredoxin compare
SMc00061 +0.6 3.0 hypothetical protein compare
SM_b21192 +0.6 4.2 fructose-1,6-bisphosphate aldolase compare
SMc02694 +0.6 1.1 ATP-dependent Clp protease adaptor compare
SMc00361 +0.6 2.4 hypothetical protein compare


Specific Phenotypes

For 10 genes in this experiment

For stress Cobalt chloride hexahydrate in Sinorhizobium meliloti 1021

For stress Cobalt chloride hexahydrate across organisms