Experiment set1IT039 for Sphingomonas koreensis DSMZ 15582

Compare to:

LB with 1-ethyl-3-methylimidazolium lysine 5 mM

200 most detrimental genes:

  gene name fitness t score description  
Ga0059261_3490 +1.3 9.7 Response regulator receiver domain/Sigma-70, region 4 compare
Ga0059261_0208 +1.3 4.0 Response regulator receiver domain compare
Ga0059261_3492 +1.1 7.0 RNA polymerase sigma factor, sigma-70 family compare
Ga0059261_3579 +0.9 5.4 hypothetical protein compare
Ga0059261_2547 +0.8 1.7 tRNA compare
Ga0059261_3947 +0.7 2.5 type II secretion system protein I (GspI) compare
Ga0059261_0035 +0.7 2.6 Uncharacterized protein conserved in bacteria compare
Ga0059261_1574 +0.7 3.2 Superfamily II DNA and RNA helicases compare
Ga0059261_0084 +0.6 1.3 hypothetical protein compare
Ga0059261_3144 +0.6 1.7 Transcriptional regulator compare
Ga0059261_3356 +0.5 1.2 hypothetical protein compare
Ga0059261_3287 +0.5 4.2 Topoisomerase IB compare
Ga0059261_2929 +0.5 1.4 oxygen-dependent methionine synthase, methyltransferase component MesD (from data) compare
Ga0059261_1756 +0.5 1.6 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes compare
Ga0059261_3727 +0.5 2.3 hypothetical protein compare
Ga0059261_1799 +0.5 1.4 Uncharacterized protein conserved in bacteria (DUF2059) compare
Ga0059261_0627 +0.5 0.9 cobalamin-5'-phosphate synthase (EC 2.7.8.26) compare
Ga0059261_1743 +0.5 1.1 hypothetical protein compare
Ga0059261_2120 +0.5 2.2 hypothetical protein compare
Ga0059261_3280 +0.5 1.4 Uncharacterized conserved protein compare
Ga0059261_3168 +0.4 2.4 peroxiredoxin, OsmC subfamily compare
Ga0059261_4143 +0.4 2.3 hypothetical protein compare
Ga0059261_0726 +0.4 1.4 hypothetical protein compare
Ga0059261_2713 +0.4 1.3 hypothetical protein compare
Ga0059261_2886 +0.4 1.9 electron transfer flavoprotein beta subunit compare
Ga0059261_0153 +0.4 1.9 Serine acetyltransferase compare
Ga0059261_1762 +0.4 0.9 hypothetical protein compare
Ga0059261_1016 +0.4 1.6 Cupin domain compare
Ga0059261_3507 +0.4 3.6 His Kinase A (phospho-acceptor) domain/Response regulator receiver domain/Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase/CHASE3 domain compare
Ga0059261_2930 +0.4 2.0 Predicted Na+-dependent transporter compare
Ga0059261_0963 +0.4 1.7 hypothetical protein compare
Ga0059261_1772 +0.4 1.0 MobA/MobL family compare
Ga0059261_0671 +0.4 1.7 Uncharacterized conserved protein compare
Ga0059261_3791 +0.4 2.9 hypothetical protein compare
Ga0059261_3581 +0.4 2.2 Alpha/beta hydrolase family compare
Ga0059261_3498 +0.4 1.6 Iron-sulfur cluster assembly accessory protein compare
Ga0059261_3491 +0.4 2.7 hypothetical protein compare
Ga0059261_1549 +0.4 1.6 hypothetical protein compare
Ga0059261_0133 +0.4 1.3 GTP-binding protein HflX compare
Ga0059261_0757 +0.4 1.2 Predicted transcriptional regulators compare
Ga0059261_3545 +0.4 0.8 hypothetical protein compare
Ga0059261_2314 +0.4 1.6 Protein-disulfide isomerase compare
Ga0059261_4139 +0.4 1.2 hypothetical protein compare
Ga0059261_4240 +0.4 2.1 hypothetical protein compare
Ga0059261_3512 +0.4 0.7 glutamate 5-kinase (EC 2.7.2.11) (from data) compare
Ga0059261_1530 +0.3 1.5 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases compare
Ga0059261_0191 +0.3 2.4 hypothetical protein compare
Ga0059261_1080 +0.3 1.2 Chemotaxis signal transduction protein compare
Ga0059261_4054 +0.3 0.9 Uncharacterized protein conserved in bacteria compare
Ga0059261_0887 +0.3 1.4 Predicted transcriptional regulators compare
Ga0059261_0252 +0.3 1.2 SpoIIAA-like compare
Ga0059261_1612 +0.3 0.5 hypothetical protein compare
Ga0059261_1049 +0.3 1.8 PEP-CTERM protein-sorting domain compare
Ga0059261_0773 +0.3 1.0 Esterase/lipase compare
Ga0059261_3646 +0.3 1.2 Uncharacterized stress protein (general stress protein 26) compare
Ga0059261_0621 +0.3 1.4 cob(I)yrinic acid a,c-diamide adenosyltransferase (EC 2.5.1.17) compare
Ga0059261_1115 +0.3 0.8 Chemotaxis protein; stimulates methylation of MCP proteins compare
Ga0059261_1652 +0.3 0.7 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily compare
Ga0059261_4046 +0.3 1.1 Response regulator receiver domain compare
Ga0059261_2933 +0.3 1.9 hypothetical protein compare
Ga0059261_1577 +0.3 2.7 L-glutamine and L-histidine transporter (from data) compare
Ga0059261_0388 +0.3 1.8 Type IV secretory pathway, VirB2 components (pilins) compare
Ga0059261_2766 +0.3 1.9 2'-5' RNA ligase compare
Ga0059261_3675 +0.3 1.3 Methyl-accepting chemotaxis protein compare
Ga0059261_2086 +0.3 0.6 SAF-like compare
Ga0059261_0631 +0.3 1.4 adenosylcobinamide kinase (EC 2.7.1.156)/adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) compare
Ga0059261_2751 +0.3 1.9 Uncharacterized protein conserved in bacteria compare
Ga0059261_1582 +0.3 2.6 Tryptophan halogenase compare
Ga0059261_3536 +0.3 1.5 hypothetical protein compare
Ga0059261_0062 +0.3 1.2 hypothetical protein compare
Ga0059261_1625 +0.3 1.8 2-keto-3-deoxy-6-phosphogluconate aldolase compare
Ga0059261_3703 +0.3 1.7 Uncharacterized conserved protein compare
Ga0059261_0014 +0.3 1.9 phosphopyruvate hydratase compare
Ga0059261_1240 +0.3 1.3 mercuric transport protein periplasmic component compare
Ga0059261_0464 +0.3 0.5 hypothetical protein compare
Ga0059261_0448 +0.3 0.6 hypothetical protein compare
Ga0059261_2951 +0.3 0.6 Heavy-metal resistance compare
Ga0059261_0039 +0.3 1.5 His Kinase A (phospho-acceptor) domain compare
Ga0059261_2371 +0.3 1.3 hypothetical protein compare
Ga0059261_1587 +0.3 1.6 hypothetical protein compare
Ga0059261_3219 +0.3 1.2 ubiquinol-cytochrome c reductase, iron-sulfur subunit compare
Ga0059261_4189 +0.3 1.3 hypothetical protein compare
Ga0059261_1261 +0.3 0.5 hypothetical protein compare
Ga0059261_0065 +0.3 1.2 ABC-type dipeptide transport system, periplasmic component compare
Ga0059261_1588 +0.3 1.8 Methyltransferase domain compare
Ga0059261_1380 +0.3 2.0 Membrane protease subunits, stomatin/prohibitin homologs compare
Ga0059261_2731 +0.3 1.4 transcriptional regulator, AraC family compare
Ga0059261_2071 +0.3 1.0 flagellar motor switch protein FliG compare
Ga0059261_4222 +0.3 1.8 Enoyl-CoA hydratase/carnithine racemase compare
Ga0059261_3048 +0.3 1.1 Transcriptional regulators compare
Ga0059261_2966 +0.3 1.4 2-deoxy-D-gluconate 3-dehydrogenase compare
Ga0059261_2097 +0.3 1.3 Rod binding protein compare
Ga0059261_3222 +0.2 1.5 adenine phosphoribosyltransferase (EC 2.4.2.7) compare
Ga0059261_2331 +0.2 1.5 hypothetical protein compare
Ga0059261_1580 +0.2 2.1 Glycosidases compare
Ga0059261_1569 +0.2 0.5 Response regulator receiver domain compare
Ga0059261_4083 +0.2 0.9 two component transcriptional regulator, LuxR family compare
Ga0059261_0750 +0.2 1.2 NADH:ubiquinone oxidoreductase subunit 3 (chain A) compare
Ga0059261_1595 +0.2 2.2 Membrane protein involved in the export of O-antigen and teichoic acid compare
Ga0059261_3237 +0.2 1.3 hypothetical protein compare
Ga0059261_1606 +0.2 1.4 Domain of unknown function (DUF4281) compare
Ga0059261_3995 +0.2 1.6 succinylarginine dihydrolase (EC 3.5.3.23) compare
Ga0059261_3518 +0.2 2.0 RND family efflux transporter, MFP subunit compare
Ga0059261_0594 +0.2 1.3 RND family efflux transporter, MFP subunit compare
Ga0059261_3027 +0.2 0.8 Predicted transcriptional regulators compare
Ga0059261_3445 +0.2 1.5 PHP domain compare
Ga0059261_4033 +0.2 1.4 Uncharacterized conserved protein compare
Ga0059261_0366 +0.2 1.6 Predicted integral membrane protein compare
Ga0059261_3718 +0.2 1.2 Protein of unknown function (DUF3140) compare
Ga0059261_3825 +0.2 1.0 thiol reductant ABC exporter, CydD subunit compare
Ga0059261_1336 +0.2 1.8 transcriptional regulator, HxlR family compare
Ga0059261_3722 +0.2 1.4 Methyltransferase domain compare
Ga0059261_2763 +0.2 1.4 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) compare
Ga0059261_1046 +0.2 1.6 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit compare
Ga0059261_1597 +0.2 1.6 hypothetical protein compare
Ga0059261_0957 +0.2 0.6 Protein of unknown function (DUF2798) compare
Ga0059261_0654 +0.2 1.1 Chemotaxis signal transduction protein compare
Ga0059261_4225 +0.2 1.2 3-isopropylmalate dehydratase, small subunit compare
Ga0059261_0493 +0.2 0.4 hypothetical protein compare
Ga0059261_0807 +0.2 0.9 RNA methyltransferase, RsmE family compare
Ga0059261_1392 +0.2 1.8 hypothetical protein compare
Ga0059261_1863 +0.2 1.7 hypothetical protein compare
Ga0059261_0132 +0.2 1.6 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family compare
Ga0059261_1260 +0.2 1.5 cobaltochelatase CobT subunit (EC 6.6.1.2) compare
Ga0059261_0745 +0.2 1.2 Uncharacterized membrane protein, required for colicin V production compare
Ga0059261_3697 +0.2 1.6 Predicted transcriptional regulators compare
Ga0059261_3327 +0.2 0.9 hypothetical protein compare
Ga0059261_1265 +0.2 0.7 hypothetical protein compare
Ga0059261_4044 +0.2 1.1 FOG: EAL domain compare
Ga0059261_2398 +0.2 1.4 hypothetical protein compare
Ga0059261_1536 +0.2 1.6 Glutathione S-transferase compare
Ga0059261_3526 +0.2 1.7 hemimethylated DNA binding domain compare
Ga0059261_1859 +0.2 1.3 Enolase C-terminal domain-like compare
Ga0059261_0244 +0.2 0.8 FOG: CheY-like receiver compare
Ga0059261_0735 +0.2 1.2 5,10-methenyltetrahydrofolate synthetase compare
Ga0059261_0989 +0.2 1.5 transporter, CPA2 family (TC 2.A.37) compare
Ga0059261_2422 +0.2 1.3 Uncharacterized protein conserved in bacteria compare
Ga0059261_1538 +0.2 0.9 Predicted transcriptional regulators compare
Ga0059261_3720 +0.2 0.8 Integral membrane protein CcmA involved in cell shape determination compare
Ga0059261_3187 +0.2 1.3 Polysaccharide deacetylase compare
Ga0059261_3721 +0.2 1.5 hypothetical protein compare
Ga0059261_2361 +0.2 1.2 Staphylococcal nuclease homologue compare
Ga0059261_3171 +0.2 1.3 Domain of unknown function (DUF4126) compare
Ga0059261_3928 +0.2 1.0 Predicted thioesterase compare
Ga0059261_4185 +0.2 0.4 hypothetical protein compare
Ga0059261_0225 +0.2 1.8 polyphosphate kinase 1 compare
Ga0059261_0220 +0.2 1.4 L-serine dehydratase, iron-sulfur-dependent, single chain form compare
Ga0059261_3440 +0.2 0.5 hypothetical protein compare
Ga0059261_1585 +0.2 2.0 Major Facilitator Superfamily compare
Ga0059261_1991 +0.2 1.1 hypothetical protein compare
Ga0059261_1570 +0.2 1.5 N-formylglutamate amidohydrolase compare
Ga0059261_3196 +0.2 0.6 Transcriptional regulator compare
Ga0059261_2471 +0.2 0.3 hypothetical protein compare
Ga0059261_2955 +0.2 1.6 Domain of unknown function (DUF4173) compare
Ga0059261_3174 +0.2 0.9 EF hand compare
Ga0059261_3773 +0.2 1.5 hypothetical protein compare
Ga0059261_3755 +0.2 0.5 Protein of unknown function (DUF2798) compare
Ga0059261_0028 +0.2 1.0 Predicted transcriptional regulators compare
Ga0059261_2528 +0.2 1.2 Uncharacterized conserved protein compare
Ga0059261_2384 +0.2 1.6 Phage capsid scaffolding protein (GPO) serine peptidase compare
Ga0059261_2684 +0.2 0.4 hypothetical protein compare
Ga0059261_3991 +0.2 1.6 Predicted hydrolase of the alpha/beta superfamily compare
Ga0059261_3238 +0.2 0.5 hypothetical protein compare
Ga0059261_3781 +0.2 1.0 hypothetical protein compare
Ga0059261_3967 +0.2 1.3 hypothetical protein compare
Ga0059261_1958 +0.2 1.0 Transcriptional regulators compare
Ga0059261_4059 +0.2 1.3 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases compare
Ga0059261_0929 +0.2 1.2 anthranilate phosphoribosyltransferase compare
Ga0059261_0869 +0.2 1.1 Acyl-CoA thioesterase compare
Ga0059261_1495 +0.2 1.6 succinylglutamic semialdehyde dehydrogenase (EC 1.2.1.71) compare
Ga0059261_0737 +0.2 1.2 PRC-barrel domain compare
Ga0059261_2461 +0.2 1.3 hypothetical protein compare
Ga0059261_3882 +0.2 0.8 dimethyladenosine transferase (EC 2.1.1.-) compare
Ga0059261_0452 +0.2 1.0 Predicted membrane protein compare
Ga0059261_1598 +0.2 1.7 hypothetical protein compare
Ga0059261_0596 +0.2 1.1 Cation efflux family compare
Ga0059261_0472 +0.2 0.8 Predicted metal-binding protein compare
Ga0059261_1546 +0.2 1.4 MerC mercury resistance protein compare
Ga0059261_2214 +0.2 1.5 hypothetical protein compare
Ga0059261_4167 +0.2 1.2 Outer membrane protein and related peptidoglycan-associated (lipo)proteins compare
Ga0059261_2060 +0.2 1.4 flagellar biosynthetic protein FliR compare
Ga0059261_0685 +0.2 0.5 pyruvate kinase compare
Ga0059261_1599 +0.2 1.7 Uncharacterized conserved protein compare
Ga0059261_1126 +0.2 0.9 Response regulator compare
Ga0059261_3132 +0.2 1.1 hypothetical protein compare
Ga0059261_2376 +0.2 1.1 phage tail protein, P2 protein I family compare
Ga0059261_1143 +0.2 1.3 flagellar hook-basal body protein compare
Ga0059261_1128 +0.2 1.5 Sigma-70 region 2 compare
Ga0059261_1144 +0.2 1.3 flagellar basal-body rod protein FlgG, Gram-negative bacteria compare
Ga0059261_2352 +0.2 0.9 hypothetical protein compare
Ga0059261_1741 +0.2 1.3 Conjugal transfer protein TraD compare
Ga0059261_0400 +0.2 1.0 hypothetical protein compare
Ga0059261_2871 +0.2 1.1 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) compare
Ga0059261_1157 +0.2 1.6 Beta-lactamase class C and other penicillin binding proteins compare
Ga0059261_1934 +0.2 0.8 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) compare
Ga0059261_2077 +0.2 1.0 Uncharacterized protein conserved in bacteria compare
Ga0059261_0879 +0.2 1.4 ribosomal RNA small subunit methyltransferase A compare
Ga0059261_3441 +0.2 0.9 hypothetical protein compare
Ga0059261_0137 +0.2 1.1 nitrogen regulation protein NR(I) compare
Ga0059261_3142 +0.2 1.5 Predicted permeases compare


Specific Phenotypes

None in this experiment

For Sphingomonas koreensis DSMZ 15582 in stress experiments

For stress 1-ethyl-3-methylimidazolium lysine across organisms