Experiment set1IT038 for Sinorhizobium meliloti 1021

Compare to:

LB with Nickel (II) chloride hexahydrate 1 mM

200 most important genes:

  gene name fitness t score description  
SMa1641 -6.6 -9.0 NreB protein conserved
SM_b20955 -6.3 -3.5 endo-beta-1,3-1,4-glycanase compare
SMc02753 -5.6 -1.2 PTS system transporter subunit IIA compare
SMc00917 -5.5 -4.6 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
SMc00334 -5.3 -1.9 cytidylate kinase compare
SMc02850 -5.2 -4.1 DNA polymerase I compare
SMc02833 -5.0 -2.2 penicillin-insensitive murein endopeptidase compare
SMc03229 -4.9 -1.8 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase compare
SMc02868 -4.7 -5.5 multidrug efflux system protein compare
SMc02149 -4.6 -1.4 hypothetical protein compare
SMc00239 -4.6 -1.0 hypothetical protein compare
SM_b20307 -4.3 -0.9 dihydroxyacetone kinase compare
SMc03878 -4.3 -3.7 acetoacetyl-CoA reductase compare
SMc02071 -4.3 -3.7 hydrolase glycosidase compare
SMc03981 -4.2 -4.7 phosphoglycerate kinase compare
SMc02909 -4.2 -1.8 transglycosylase transmembrane protein compare
SMc01208 -4.0 -2.8 peptidyl-prolyl cis-trans isomerase B protein compare
SMc02307 -4.0 -9.3 histidinol dehydrogenase compare
SMc00726 -4.0 -0.9 thiol:disulfide interchange redox-active center transmembrane protein compare
SMa1002 -4.0 -1.9 hypothetical protein compare
SMc00918 -4.0 -7.6 ATP phosphoribosyltransferase regulatory subunit compare
SMc02144 -4.0 -4.8 phosphate ABC transporter permease compare
SMc02246 -3.9 -0.8 hypothetical protein compare
SMc00302 -3.9 -2.2 hypothetical protein compare
SMc01880 -3.8 -3.3 pantoate--beta-alanine ligase compare
SMc02838 -3.8 -4.7 phosphoglyceromutase compare
SMc02266 -3.7 -1.6 hypothetical protein compare
SMc01361 -3.7 -5.9 dihydroorotase compare
SMc00619 -3.7 -2.1 hypothetical protein compare
SMc00296 -3.6 -12.0 POLY3-hydroxybutyrate polymerase compare
SMc02140 -3.6 -1.6 phosphate regulon transcriptional regulatory protein compare
SMc02142 -3.6 -4.4 phosphate transporter ATP-binding protein compare
SMc00987 -3.6 -2.9 hypothetical protein compare
SMc03967 -3.6 -1.3 Holliday junction resolvase compare
SMc02147 -3.5 -6.1 phosphate regulon sensor histidine kinase transmembrane protein compare
SMc00970 -3.5 -2.1 exodeoxyribonuclease VII small subunit compare
SMa1639 -3.4 -1.0 hypothetical protein compare
SMc00576 -3.4 -3.8 hypothetical protein compare
SMa0789 -3.4 -4.6 GntR family transcriptional regulator compare
SMc00602 -3.3 -6.1 excinuclease ABC subunit C compare
SMc01207 -3.3 -2.7 S-adenosylmethionine--tRNA ribosyltransferase-isomerase compare
SMc02569 -3.3 -3.4 imidazole glycerol phosphate synthase subunit HisF compare
SMc00073 -3.3 -2.3 hypothetical protein compare
SMc02827 -3.3 -4.2 hypothetical protein compare
SMc01885 -3.3 -7.7 aminopeptidase P protein compare
SMc04330 -3.3 -2.5 trimethylamine methyltransferase compare
SMc01147 -3.3 -4.1 coproporphyrinogen III oxidase compare
SMc00511 -3.3 -4.9 D-ribulose-5-phosphate 3-epimerase compare
SMc01347 -3.3 -3.9 hypothetical protein compare
SMc02825 -3.2 -4.1 aminopeptidase compare
SMc01028 -3.2 -10.3 phosphopyruvate hydratase compare
SMc01568 -3.2 -0.9 hypothetical protein compare
SMc02572 -3.1 -2.6 imidazole glycerol phosphate synthase subunit HisH compare
SMc02520 -3.1 -10.0 glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) (from data) compare
SMc02867 -3.1 -3.9 multidrug-efflux system transmembrane protein compare
SMc03978 -3.0 -3.9 transketolase compare
SMc00585 -3.0 -7.0 leucyl aminopeptidase conserved
SMc00492 -3.0 -0.9 hypothetical protein compare
SMc03763 -2.9 -3.3 cytosine-specific methyltransferase compare
SMc02143 -2.9 -4.0 phosphate ABC transporter permease compare
SMc01004 -2.9 -11.6 phosphoribosyl-AMP cyclohydrolase compare
SMc00876 -2.9 -4.2 ATP-binding MRP protein compare
SMc01337 -2.9 -1.2 hypothetical protein compare
SMc01342 -2.8 -5.6 hypothetical protein compare
SMc02570 -2.8 -5.0 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
SMc02145 -2.8 -0.9 signal peptide protein compare
SMc00352 -2.8 -2.1 acetyltransferase compare
SM_b20105 -2.8 -1.5 transcriptional regulator compare
SMc02141 -2.8 -3.3 phosphate transporter PhoU compare
SM_b21213 -2.7 -4.2 serinethreonine protein phosphatase compare
SMc02165 -2.6 -7.1 orotate phosphoribosyltransferase compare
SMc00461 -2.6 -1.3 deoxyuridine 5'-triphosphate nucleotidohydrolase compare
SMc00580 -2.6 -3.3 4-hydroxythreonine-4-phosphate dehydrogenase compare
SMc04024 -2.6 -6.4 membrane-bound lytic murein transglycosylase compare
SMa1323 -2.6 -1.9 Transcription regulator compare
SMc01206 -2.4 -1.6 queuine tRNA-ribosyltransferase compare
SMc00006 -2.4 -2.8 hypothetical protein compare
SMc02102 -2.4 -3.3 hypothetical protein compare
SMc01881 -2.4 -3.0 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
SM_b20942 -2.3 -4.4 UDP glucose 4-epimerase compare
SMc00981 -2.3 -5.8 ferredoxin protein compare
SMc00857 -2.3 -6.7 protease compare
SMc02574 -2.2 -4.5 imidazoleglycerol-phosphate dehydratase compare
SMc00982 -2.2 -4.5 dioxygenase compare
SMc02484 -2.2 -3.3 amino acid efflux transmembrane protein compare
SMc01845 -2.2 -1.7 transglycosylase transmembrane protein compare
SMc00129 -2.2 -6.3 sensor histidine kinase compare
SMc03127 -2.2 -1.5 ABC transporter permease compare
SMc00725 -2.1 -3.5 argininosuccinate lyase compare
SMc00412 -2.1 -3.9 orotidine 5'-phosphate decarboxylase compare
SMc01235 -2.1 -9.5 excinuclease ABC subunit A compare
SMc00017 -2.1 -1.2 homoserine kinase compare
SMc01183 -2.1 -1.2 LexA repressor compare
SMc02050 -2.0 -3.4 trigger factor compare
SMc02114 -2.0 -3.3 hypothetical protein compare
SMc01178 -2.0 -1.1 multidrug transmembrane resistance signal peptide protein compare
SMc04042 -2.0 -3.1 monophosphatase compare
SM_b20758 -2.0 -2.2 ArsR family transcriptional regulator compare
SMc03140 -2.0 -4.4 transcriptional regulator compare
SMc02495 -2.0 -1.3 translaldolase compare
SM_b20048 -1.9 -5.9 transcriptional regulator compare
SMc03849 -1.9 -1.1 heme exporter C (cytochrome C-type biogenesis protein) transmembrane compare
SMc02370 -1.9 -13.0 aminopeptidase N conserved
SMc02582 -1.9 -3.0 hypothetical protein compare
SMc01360 -1.9 -2.5 aspartate carbamoyltransferase catalytic subunit compare
SMc01850 -1.9 -1.7 hypothetical protein compare
SMc01438 -1.9 -4.0 protease precursor signal peptide protein compare
SMc02245 -1.9 -4.4 dihydroorotate dehydrogenase 2 compare
SMc03780 -1.9 -2.9 hypothetical protein compare
SMc03773 -1.8 -3.3 hypothetical protein compare
SMc01091 -1.8 -1.9 hypothetical protein compare
SMc01144 -1.8 -2.2 ribonuclease PH compare
SMc02861 -1.8 -1.7 phosphate transporter compare
SMc00859 -1.8 -1.7 hypothetical protein compare
SMc04346 -1.8 -4.4 ketol-acid reductoisomerase compare
SMc04003 -1.8 -1.2 50S ribosomal protein L36 compare
SMc02543 -1.7 -4.0 hypothetical protein compare
SMc01007 -1.7 -1.5 hypothetical protein compare
SMa0882 -1.7 -1.1 hypothetical protein compare
SMc00856 -1.7 -0.9 hypothetical protein compare
SMc01724 -1.7 -1.7 hypothetical protein compare
SMa1099 -1.7 -1.8 CycB1 cytochrome c-552 precursor compare
SMc04231 -1.7 -5.4 excinuclease ABC subunit B compare
SMc03120 -1.7 -1.7 ABC transporter ATP-binding protein compare
SMc01853 -1.6 -1.9 hypothetical protein compare
SM_b20728 -1.6 -1.6 hypothetical protein compare
SMc01700 -1.6 -3.0 peptidyl-prolyl cis-trans isomerase A compare
SMc03053 -1.6 -0.9 flagellar biosynthesis protein FliQ compare
SMa0643 -1.6 -1.1 transposase compare
SMc02363 -1.6 -2.3 cytochrome C-type biogenesis transmembrane protein compare
SMc02894 -1.6 -2.3 hypothetical protein compare
SMc00569 -1.6 -1.7 hypothetical protein compare
SMc00241 -1.6 -1.8 transcriptional regulator compare
SM_b20946 -1.6 -4.9 galactosyltransferase compare
SMc02901 -1.6 -0.7 hypothetical protein compare
SMc03836 -1.6 -1.0 acyl-CoA thioesterase i protein compare
SMc04175 -1.6 -4.8 transmembrane protein compare
SMc02505 -1.5 -1.2 hypothetical protein compare
SM_b20880 -1.5 -6.1 ATP-dependent RNA helicase compare
SMc01578 -1.5 -7.5 aspartate aminotransferase compare
SMc00948 -1.5 -7.8 glutamine synthetase compare
SMc04052 -1.5 -1.0 transcriptional regulator compare
SMc02306 -1.5 -1.0 hypothetical protein compare
SMc01236 -1.5 -2.9 hypothetical protein compare
SMc01457 -1.5 -6.3 transport transmembrane protein compare
SM_b20302 -1.5 -1.3 hypothetical protein compare
SMc04404 -1.4 -1.0 amino acid efflux transmembrane protein compare
SMc01461 -1.4 -3.1 DNA helicase II protein compare
SMc03124 -1.4 -2.7 periplasmic binding ABC transporter protein compare
SMc01315 -1.4 -0.8 hypothetical protein compare
SMc01764 -1.4 -5.8 arginyl-tRNA-protein transferase compare
SMc02485 -1.4 -1.1 signal peptide protein compare
SMc03010 -1.4 -2.2 chemotaxis-specific methylesterase compare
SMc00565 -1.4 -0.7 50S ribosomal protein L9 compare
SM_b21128 -1.4 -5.2 hypothetical protein compare
SMc04028 -1.4 -9.5 glutamate synthase compare
SMc01515 -1.4 -1.4 hypothetical protein compare
SMc00012 -1.4 -1.0 cytochrome C oxidase assembly protein compare
SM_b21551 -1.4 -0.7 hypothetical protein compare
SMc00691 -1.3 -2.2 site-specific tyrosine recombinase XerD compare
SMc03091 -1.3 -2.7 arginase compare
SMc00762 -1.3 -5.1 glutamine synthetase compare
SM_b21170 -1.3 -1.9 guanylate kinase compare
SMc01768 -1.3 -2.5 transcriptional regulator compare
SMc01151 -1.3 -3.2 hypothetical protein compare
SMc00897 -1.3 -4.8 PMBA protein compare
SMc02232 -1.3 -1.3 hypothetical protein compare
SMc01215 -1.3 -3.0 carbamoyl phosphate synthase large subunit compare
SM_b20655 -1.3 -1.5 hypothetical protein compare
SM_b20909 -1.3 -1.3 hypothetical protein compare
SMc02856 -1.3 -5.9 penicillin-binding protein compare
SMc02172 -1.3 -5.1 transcriptional regulator compare
SMc04026 -1.3 -6.4 glutamate synthase compare
SMc00329 -1.3 -1.5 iron response regulator protein compare
SMc02166 -1.3 -4.2 dihydroorotase compare
SMa0211 -1.3 -0.8 hypothetical protein compare
SMc02707 -1.3 -1.2 hypothetical protein compare
SMc00419 -1.3 -2.3 glutathione synthetase compare
SMc00369 -1.3 -0.9 oxidoreductase compare
SMc00976 -1.3 -1.1 enoyl-CoA hydratase compare
SMc04121 -1.3 -1.2 uracil phosphoribosyltransferase compare
SMc04400 -1.3 -3.1 oxidoreductase compare
SMc02115 -1.3 -0.5 hypothetical protein compare
SMc02785 -1.2 -3.2 lytic murein transglycosylase A protein compare
SMc00566 -1.2 -1.9 hypothetical protein compare
SM_b20026 -1.2 -0.9 hypothetical protein compare
SMc00003 -1.2 -1.8 chaperone protein compare
SMc01110 -1.2 -3.8 DNA-binding protein compare
SMc02425 -1.2 -2.3 transcriptional regulator compare
SMc04319 -1.2 -0.9 hypothetical protein compare
SMc03835 -1.2 -2.3 2'-5' RNA ligase compare
SMa0232 -1.2 -1.9 hypothetical protein compare
SMc03235 -1.2 -2.4 hypothetical protein compare
SMc02362 -1.2 -1.9 cytochrome c-type biogenesis protein CcmE compare
SM_b20862 -1.2 -2.0 hypothetical protein compare
SMc00641 -1.2 -4.6 D-3-phosphoglycerate dehydrogenase compare
SMc02573 -1.2 -1.3 hypothetical protein compare
SMc00937 -1.2 -5.0 TRK system potassium uptake transmembrane protein compare
SMc03242 -1.2 -1.5 GTP-binding protein compare
SMc00184 -1.2 -3.0 tRNA/rRNA methyltransferase compare


Specific Phenotypes

For 37 genes in this experiment

For stress Nickel (II) chloride hexahydrate in Sinorhizobium meliloti 1021

For stress Nickel (II) chloride hexahydrate across organisms