Experiment set1IT037 for Pseudomonas fluorescens FW300-N2E2

Compare to:

LB with sodium fluoride 12.5 mM

200 most detrimental genes:

  gene name fitness t score description  
Pf6N2E2_4418 +1.9 3.7 Diaminopimelate epimerase (EC 5.1.1.7) compare
Pf6N2E2_4153 +1.9 4.7 Sensory box histidine kinase compare
Pf6N2E2_2752 +1.8 12.4 Exported zinc metalloprotease YfgC precursor compare
Pf6N2E2_3941 +1.6 6.5 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf6N2E2_3661 +1.5 7.0 hypothetical protein compare
Pf6N2E2_3843 +1.4 12.8 MFS permease conserved
Pf6N2E2_3659 +1.4 7.3 Protein fixF compare
Pf6N2E2_2755 +1.3 4.2 Sigma factor RpoE negative regulatory protein RseA compare
Pf6N2E2_3663 +1.3 8.2 Glycosyl transferase compare
Pf6N2E2_3664 +1.1 8.2 Carbamoyltransferase in large core OS assembly cluster compare
Pf6N2E2_3658 +1.1 6.5 Lipid A core - O-antigen ligase and related enzymes compare
Pf6N2E2_5150 +1.1 4.9 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf6N2E2_3791 +1.1 8.5 Glucans biosynthesis glucosyltransferase H (EC 2.4.1.-) compare
Pf6N2E2_2507 +1.1 5.8 Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-) compare
Pf6N2E2_827 +1.0 3.5 probable dioxygenase compare
Pf6N2E2_3792 +1.0 5.3 Glucans biosynthesis protein G precursor compare
Pf6N2E2_3655 +1.0 7.8 Hypothetical protein FIG015671 in large core OS assembly cluster compare
Pf6N2E2_5771 +0.9 6.3 FKBP-type peptidyl-prolyl cis-trans isomerase FklB (EC 5.2.1.8) compare
Pf6N2E2_3667 +0.9 1.3 Heptose kinase WapQ, eukaryotic type compare
Pf6N2E2_2510 +0.9 3.2 Lipid carrier : UDP-N-acetylgalactosaminyltransferase (EC 2.4.1.-) / Alpha-1,3-N-acetylgalactosamine transferase PglA (EC 2.4.1.-); Putative glycosyltransferase compare
Pf6N2E2_6058 +0.9 4.4 FIG139976: hypothetical protein compare
Pf6N2E2_2508 +0.9 3.1 hypothetical protein compare
Pf6N2E2_37 +0.9 4.1 6-carboxytetrahydropterin synthase (EC 4.1.2.50) @ Queuosine biosynthesis QueD, PTPS-I compare
Pf6N2E2_1092 +0.9 2.2 Probable vanillate O-demethylase oxygenase subunit oxidoreductase protein (EC 1.14.13.-) compare
Pf6N2E2_2513 +0.8 2.6 UDP-glucose dehydrogenase (EC 1.1.1.22) compare
Pf6N2E2_2823 +0.8 3.9 Multidrug efflux RND membrane fusion protein MexC compare
Pf6N2E2_4556 +0.8 3.1 FIG00953078: hypothetical protein compare
Pf6N2E2_3665 +0.8 1.4 serine/threonine protein kinase compare
Pf6N2E2_4943 +0.8 3.8 PspA/IM30 family protein compare
Pf6N2E2_2582 +0.8 3.6 Flagellar motor switch protein FliN compare
Pf6N2E2_6057 +0.8 3.3 FIG002781: Alpha-L-glutamate ligase family protein compare
Pf6N2E2_919 +0.8 2.4 FIG00954373: hypothetical protein compare
Pf6N2E2_5843 +0.8 2.5 hypothetical protein compare
Pf6N2E2_2597 +0.8 6.5 Flagellar regulatory protein FleQ compare
Pf6N2E2_309 +0.8 1.4 FIG00957702: hypothetical protein compare
Pf6N2E2_5394 +0.8 3.8 Molybdenum cofactor biosynthesis protein MoaE compare
Pf6N2E2_5571 +0.8 1.4 hypothetical protein compare
Pf6N2E2_3635 +0.8 2.7 FIG00953138: hypothetical protein compare
Pf6N2E2_2967 +0.8 2.4 Cold shock protein CspA compare
Pf6N2E2_3842 +0.8 4.5 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_3634 +0.8 0.8 Transporter compare
Pf6N2E2_5705 +0.8 1.7 Sensor protein PhoQ (EC 2.7.13.3) compare
Pf6N2E2_4803 +0.7 1.6 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_1452 +0.7 2.5 hypothetical protein compare
Pf6N2E2_5226 +0.7 1.4 FIG00955589: hypothetical protein compare
Pf6N2E2_2594 +0.7 5.2 Flagellar hook-basal body complex protein FliE compare
Pf6N2E2_1987 +0.7 1.8 hypothetical protein compare
Pf6N2E2_2440 +0.7 1.3 Free methionine-(R)-sulfoxide reductase, contains GAF domain compare
Pf6N2E2_3328 +0.7 1.7 transcriptional regulator compare
Pf6N2E2_2578 +0.7 2.2 Flagellar biosynthesis protein FliR compare
Pf6N2E2_440 +0.7 3.0 FIG00954920: hypothetical protein compare
Pf6N2E2_2938 +0.7 4.1 Outer membrane lipoprotein compare
Pf6N2E2_2583 +0.7 4.2 Flagellar motor switch protein FliM compare
Pf6N2E2_5156 +0.7 2.2 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_5720 +0.7 5.8 BarA sensory histidine kinase (= VarS = GacS) compare
Pf6N2E2_923 +0.7 2.0 Haloacid dehalogenase, type II (EC 3.8.1.2) compare
Pf6N2E2_4611 +0.7 2.5 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_445 +0.7 4.4 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) compare
Pf6N2E2_1403 +0.7 2.1 Nitrous oxide reductase maturation protein, outer-membrane lipoprotein NosL compare
Pf6N2E2_724 +0.7 2.1 Nitric oxide -responding transcriptional regulator Dnr (Crp/Fnr family) compare
Pf6N2E2_1983 +0.6 1.7 hypothetical protein compare
Pf6N2E2_4973 +0.6 1.9 Inner membrane protein compare
Pf6N2E2_2590 +0.6 4.4 Flagellum-specific ATP synthase FliI compare
Pf6N2E2_1844 +0.6 2.6 MaoC-related acyl dehydratase compare
Pf6N2E2_4810 +0.6 4.1 Glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) compare
Pf6N2E2_3778 +0.6 2.9 FIG00954300: hypothetical protein compare
Pf6N2E2_3039 +0.6 3.2 Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) compare
Pf6N2E2_1056 +0.6 0.9 Quinone oxidoreductase (EC 1.6.5.5) compare
Pf6N2E2_2627 +0.6 3.0 Flagellar basal-body rod protein FlgG compare
Pf6N2E2_5499 +0.6 1.3 hypothetical protein compare
Pf6N2E2_5342 +0.6 2.2 21 kDa hemolysin precursor compare
Pf6N2E2_4614 +0.6 2.8 twitching motility protein PilH compare
Pf6N2E2_5986 +0.6 2.4 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_6087 +0.6 1.6 Short-chain dehydrogenase/reductase SDR compare
Pf6N2E2_773 +0.6 3.6 Undecaprenyl-diphosphatase (EC 3.6.1.27) compare
Pf6N2E2_2013 +0.6 1.2 hypothetical protein compare
Pf6N2E2_4918 +0.6 1.9 Ribonucleotide reductase transcriptional regulator NrdR compare
Pf6N2E2_5476 +0.6 1.8 Aldehyde dehydrogenase (EC 1.2.1.3) compare
Pf6N2E2_5050 +0.6 2.7 hypothetical protein compare
Pf6N2E2_5340 +0.6 2.1 Stringent starvation protein A compare
Pf6N2E2_4365 +0.6 4.3 Ribonuclease PH (EC 2.7.7.56) compare
Pf6N2E2_2734 +0.6 2.9 Transcriptional regulator, LysR family compare
Pf6N2E2_3761 +0.6 5.5 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) compare
Pf6N2E2_1006 +0.6 2.1 Ribose ABC transport system, periplasmic ribose-binding protein RbsB (TC 3.A.1.2.1) compare
Pf6N2E2_1340 +0.6 2.0 major pilin protein fimA compare
Pf6N2E2_1124 +0.6 1.3 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_6090 +0.6 1.5 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain compare
Pf6N2E2_3323 +0.6 2.4 hypothetical protein compare
Pf6N2E2_1032 +0.6 0.9 Alkanesulfonates ABC transporter ATP-binding protein / Sulfonate ABC transporter, ATP-binding subunit SsuB compare
Pf6N2E2_2824 +0.6 4.3 RND efflux system, inner membrane transporter CmeB compare
Pf6N2E2_2577 +0.6 3.9 Flagellar biosynthesis protein FlhB compare
Pf6N2E2_2288 +0.6 2.6 FIG00953423: hypothetical protein compare
Pf6N2E2_4743 +0.6 1.0 hypothetical protein compare
Pf6N2E2_3969 +0.6 0.7 Membrane-fusion protein compare
Pf6N2E2_3171 +0.6 1.3 hypothetical protein compare
Pf6N2E2_4187 +0.6 2.0 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_2585 +0.6 3.8 Flagellar hook-length control protein FliK compare
Pf6N2E2_2592 +0.5 3.2 Flagellar motor switch protein FliG compare
Pf6N2E2_5346 +0.5 2.4 rRNA small subunit methyltransferase I compare
Pf6N2E2_1876 +0.5 1.5 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) compare
Pf6N2E2_4618 +0.5 3.0 Chemotaxis signal transduction protein compare
Pf6N2E2_4751 +0.5 2.7 response regulator compare
Pf6N2E2_5755 +0.5 2.5 FIG00956435: hypothetical protein compare
Pf6N2E2_199 +0.5 1.7 hypothetical protein compare
Pf6N2E2_2576 +0.5 4.5 Flagellar biosynthesis protein FlhA compare
Pf6N2E2_5667 +0.5 3.0 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_5697 +0.5 4.7 Flagellar hook protein FlgE compare
Pf6N2E2_1321 +0.5 2.0 MoaF protein precursor compare
Pf6N2E2_1701 +0.5 1.9 ABC transporter ATP-binding protein compare
Pf6N2E2_3179 +0.5 1.5 FIG021952: putative membrane protein compare
Pf6N2E2_1034 +0.5 1.2 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_3258 +0.5 3.0 Uncharacterized ABC transporter, periplasmic component YrbD compare
Pf6N2E2_2964 +0.5 2.1 FIG006285: ICC-like protein phosphoesterase compare
Pf6N2E2_2022 +0.5 3.0 BarA-associated response regulator UvrY (= GacA = SirA) compare
Pf6N2E2_4541 +0.5 1.2 hypothetical protein compare
Pf6N2E2_2110 +0.5 2.6 LysR family transcriptional regulator near succinyl-CoA:3-ketoacid-coenzyme A transferase compare
Pf6N2E2_464 +0.5 1.9 Sensory histidine kinase QseC compare
Pf6N2E2_3122 +0.5 1.9 Chemotaxis signal transduction protein compare
Pf6N2E2_1775 +0.5 2.4 Chemotaxis response regulator protein-glutamate methylesterase CheB (EC 3.1.1.61) compare
Pf6N2E2_3763 +0.5 1.0 hypothetical protein compare
Pf6N2E2_5906 +0.5 1.9 Flp pilus assembly protein, pilin Flp compare
Pf6N2E2_116 +0.5 2.9 Glycosyltransferase compare
Pf6N2E2_3300 +0.5 1.8 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf6N2E2_1984 +0.5 1.7 probable exported protein STY4558 compare
Pf6N2E2_4494 +0.5 2.4 Adenylate cyclase (EC 4.6.1.1) compare
Pf6N2E2_420 +0.5 1.4 Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY compare
Pf6N2E2_572 +0.5 1.3 hypothetical protein compare
Pf6N2E2_2219 +0.5 1.4 Cell division trigger factor (EC 5.2.1.8) compare
Pf6N2E2_1981 +0.5 2.4 FIG051360: Periplasmic protein TonB, links inner and outer membranes compare
Pf6N2E2_6007 +0.5 2.2 Glutathione S-transferase (EC 2.5.1.18) compare
Pf6N2E2_5160 +0.5 1.6 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_5031 +0.5 3.3 hypothetical protein compare
Pf6N2E2_296 +0.5 3.0 Thioredoxin reductase (EC 1.8.1.9) compare
Pf6N2E2_5555 +0.5 1.3 Cold shock protein CspA compare
Pf6N2E2_5696 +0.5 3.3 Flagellar basal-body rod modification protein FlgD compare
Pf6N2E2_5006 +0.5 3.3 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_665 +0.5 1.8 Acetoin dehydrogenase E1 component alpha-subunit (EC 1.2.4.-) compare
Pf6N2E2_5694 +0.5 2.7 Flagellar basal-body rod protein FlgB compare
Pf6N2E2_629 +0.5 1.6 2-ketogluconate kinase (EC 2.7.1.13) compare
Pf6N2E2_2124 +0.5 1.2 Mg(2+) transport ATPase protein C compare
Pf6N2E2_2071 +0.5 1.1 hypothetical protein compare
Pf6N2E2_2628 +0.5 2.6 Flagellar basal-body rod protein FlgF compare
Pf6N2E2_367 +0.5 1.1 Acetylornithine deacetylase (EC 3.5.1.16) compare
Pf6N2E2_6045 +0.5 1.1 hypothetical protein compare
Pf6N2E2_5392 +0.5 2.3 Molybdenum cofactor biosynthesis protein MoaC compare
Pf6N2E2_1379 +0.5 2.0 Sensory box histidine kinase/response regulator compare
Pf6N2E2_5520 +0.5 2.8 Sensory box histidine kinase compare
Pf6N2E2_3204 +0.5 1.5 Rho-specific inhibitor of transcription termination (YaeO) compare
Pf6N2E2_4996 +0.5 1.7 LSU m3Psi1915 methyltransferase RlmH compare
Pf6N2E2_5444 +0.5 1.8 Phosphoribosylglycinamide formyltransferase 2 (EC 2.1.2.-) compare
Pf6N2E2_1161 +0.5 2.6 FIG00961921: hypothetical protein compare
Pf6N2E2_2396 +0.5 1.8 Sensor histidine kinase compare
Pf6N2E2_2788 +0.5 1.1 Transcriptional regulator, AsnC family compare
Pf6N2E2_5494 +0.5 2.6 Pyruvate kinase (EC 2.7.1.40) compare
Pf6N2E2_5158 +0.5 2.1 FIG00954153: hypothetical protein compare
Pf6N2E2_1312 +0.5 1.1 4-hydroxyphenylacetate symporter, major facilitator superfamily (MFS) compare
Pf6N2E2_2296 +0.5 1.7 FIG00954767: hypothetical protein compare
Pf6N2E2_5573 +0.5 1.7 Glycerol-3-phosphate regulon repressor, DeoR family compare
Pf6N2E2_4054 +0.4 1.8 Osmotically inducible protein C compare
Pf6N2E2_5712 +0.4 1.7 DNA-3-methyladenine glycosylase (EC 3.2.2.20) compare
Pf6N2E2_6047 +0.4 1.1 hypothetical protein compare
Pf6N2E2_3849 +0.4 1.0 FIG00954739: hypothetical protein compare
Pf6N2E2_15 +0.4 2.0 Pyoverdine biosynthesis related protein PvdP compare
Pf6N2E2_1762 +0.4 1.9 putative lipase compare
Pf6N2E2_4492 +0.4 2.4 FIG00953395: hypothetical protein compare
Pf6N2E2_715 +0.4 2.1 putative membrane protein compare
Pf6N2E2_5487 +0.4 2.5 Nitrogen regulation protein NR(I) compare
Pf6N2E2_2933 +0.4 2.1 hypothetical protein compare
Pf6N2E2_2563 +0.4 3.5 FIG00953562: hypothetical protein compare
Pf6N2E2_2152 +0.4 1.1 hypothetical protein compare
Pf6N2E2_3610 +0.4 2.5 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_1975 +0.4 1.4 Integrase regulator R compare
Pf6N2E2_648 +0.4 1.0 General secretion pathway protein K compare
Pf6N2E2_3656 +0.4 2.6 Probable transcription regulator Mig-14 compare
Pf6N2E2_2625 +0.4 2.5 Flagellar P-ring protein FlgI compare
Pf6N2E2_3499 +0.4 2.1 Permeases of the major facilitator superfamily compare
Pf6N2E2_5545 +0.4 1.6 Queuosine Biosynthesis QueE Radical SAM compare
Pf6N2E2_5919 +0.4 1.6 Flp pilus assembly protein TadD, contains TPR repeats compare
Pf6N2E2_2746 +0.4 2.7 Outer membrane protein NlpB, lipoprotein component of the protein assembly complex (forms a complex with YaeT, YfiO, and YfgL); Lipoprotein-34 precursor compare
Pf6N2E2_5178 +0.4 1.1 CDP-diacylglycerol--serine O-phosphatidyltransferase (EC 2.7.8.8) compare
Pf6N2E2_1548 +0.4 1.9 Lactoylglutathione lyase compare
Pf6N2E2_884 +0.4 2.5 Inosose isomerase (EC 5.3.99.-) compare
Pf6N2E2_6060 +0.4 2.0 Propionate catabolism operon transcriptional regulator of GntR family [predicted] compare
Pf6N2E2_1089 +0.4 0.8 Delta 1-piperideine-2-carboxylate reductase (EC 1.5.1.21) / Delta 1-pyrroline-2-carboxylate reductase (EC 1.5.1.1) compare
Pf6N2E2_1308 +0.4 1.7 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) / 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) compare
Pf6N2E2_2911 +0.4 2.6 Acetyl-CoA carboxylase alpha subunit compare
Pf6N2E2_2340 +0.4 1.6 Transcriptional regulator, GntR family compare
Pf6N2E2_2910 +0.4 2.0 Carbamate kinase (EC 2.7.2.2) compare
Pf6N2E2_344 +0.4 1.8 hypothetical protein compare
Pf6N2E2_74 +0.4 1.3 DedD protein compare
Pf6N2E2_2144 +0.4 2.0 Cell division transporter, ATP-binding protein FtsE (TC 3.A.5.1.1) compare
Pf6N2E2_3839 +0.4 2.2 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_6100 +0.4 1.4 tRNA-Val-TAC compare
Pf6N2E2_316 +0.4 1.5 membrane protein, putative compare
Pf6N2E2_1294 +0.4 1.1 Carbon starvation protein A compare
Pf6N2E2_2869 +0.4 0.9 Peptide deformylase (EC 3.5.1.88) compare
Pf6N2E2_3588 +0.4 1.9 hypothetical protein compare
Pf6N2E2_4499 +0.4 1.3 protein of unknown function DUF86 compare
Pf6N2E2_3429 +0.4 1.5 hypothetical protein compare
Pf6N2E2_2509 +0.4 0.9 UDP-glucose 4-epimerase (EC 5.1.3.2) compare


Specific Phenotypes

For 2 genes in this experiment

For stress sodium fluoride in Pseudomonas fluorescens FW300-N2E2

For stress sodium fluoride across organisms