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Experiment set1IT037 for
Methanococcus maripaludis JJ
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Formate McCas, 2.5g/L bicarb, 200 mM MOPs, 20 psi N2CO2, SO4 FREE
200 most important genes:
gene
name
fitness
t score
description
MMJJ
_RS08855
-6.5
-3.5
cyclic pyranopterin monophosphate synthase MoaC
compare
MMJJ
_RS07665
-5.8
-29.5
formate dehydrogenase subunit alpha
compare
MMJJ
_RS07670
-5.6
-20.1
Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain
compare
MMJJ
_RS06600
-5.4
-3.0
DUF555 domain-containing protein
compare
MMJJ
_RS02055
-5.4
-13.9
GTP 3',8-cyclase MoaA
compare
MMJJ
_RS08005
-5.4
-21.2
formate dehydrogenase accessory sulfurtransferase FdhD
compare
MMJJ
_RS07655
-5.3
-15.3
hypothetical protein
compare
MMJJ
_RS03065
-5.2
-15.0
CBS domain-containing protein
compare
MMJJ
_RS05155
-5.2
-6.1
5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH
compare
MMJJ
_RS06860
-5.1
-3.5
hypothetical protein
compare
MMJJ
_RS07660
-4.9
-12.5
carbonic anhydrase
compare
MMJJ
_RS00580
-4.9
-2.0
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG
compare
MMJJ
_RS00055
-4.9
-13.5
CO dehydrogenase/acetyl-CoA synthase subunit delta
compare
MMJJ
_RS00050
-4.8
-14.1
AAA family ATPase
compare
MMJJ
_RS06725
-4.8
-10.3
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMJJ
_RS05445
-4.8
-2.3
2-oxoacid:acceptor oxidoreductase subunit alpha
compare
MMJJ
_RS07995
-4.8
-8.1
molybdenum cofactor biosynthesis protein MoaE
compare
MMJJ
_RS00645
-4.7
-10.9
adenosylmethionine--8-amino-7-oxononanoate transaminase
compare
MMJJ
_RS06260
-4.7
-9.4
6-carboxyhexanoate--CoA ligase
compare
MMJJ
_RS00275
-4.6
-2.5
coenzyme F420-0:L-glutamate ligase
compare
MMJJ
_RS00450
-4.6
-2.2
DUF126 domain-containing protein
compare
MMJJ
_RS06265
-4.6
-15.4
8-amino-7-oxononanoate synthase
compare
MMJJ
_RS04050
-4.5
-1.9
dihydroneopterin aldolase family protein
compare
MMJJ
_RS00070
-4.5
-3.7
CooT family nickel-binding protein
compare
MMJJ
_RS05575
-4.5
-4.4
2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase
compare
MMJJ
_RS04485
-4.5
-12.1
riboflavin synthase
compare
MMJJ
_RS08080
-4.5
-8.0
TIGR00300 family protein
compare
MMJJ
_RS05535
-4.4
-14.8
hypothetical protein
compare
MMJJ
_RS02920
-4.4
-2.1
30S ribosomal protein S27ae
compare
MMJJ
_RS06155
-4.4
-4.3
phosphatidylglycerophosphatase A
compare
MMJJ
_RS00040
-4.4
-10.5
CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon
compare
MMJJ
_RS00060
-4.4
-21.4
acetyl-CoA decarbonylase/synthase complex subunit gamma
compare
MMJJ
_RS06375
-4.4
-3.0
UbiX family flavin prenyltransferase
compare
MMJJ
_RS00935
-4.3
-18.6
nickel pincer cofactor biosynthesis protein LarB
compare
MMJJ
_RS06240
-4.3
-2.6
dihydropteroate synthase-like protein
compare
MMJJ
_RS06855
-4.2
-1.8
DUF2104 domain-containing protein
compare
MMJJ
_RS00045
-4.2
-20.3
CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta
compare
MMJJ
_RS03920
-4.2
-17.4
nickel pincer cofactor biosynthesis protein LarC
compare
MMJJ
_RS00075
-4.2
-15.9
AAA family ATPase
compare
MMJJ
_RS00370
-4.2
-2.0
asparagine synthase (glutamine-hydrolyzing)
compare
MMJJ
_RS06915
-4.2
-17.7
helix-turn-helix domain-containing protein
compare
MMJJ
_RS08035
-4.2
-9.8
cobalt-precorrin-7 (C(5))-methyltransferase
compare
MMJJ
_RS07980
-4.1
-15.1
biotin synthase BioB
compare
MMJJ
_RS03620
-4.1
-4.8
DUF2097 domain-containing protein
compare
MMJJ
_RS00035
-4.1
-20.7
CO dehydrogenase/acetyl-CoA synthase complex subunit alpha
compare
MMJJ
_RS08625
-4.1
-2.8
magnesium/cobalt transporter CorA
compare
MMJJ
_RS01750
-4.1
-2.4
ferrous iron transport protein A
compare
MMJJ
_RS07975
-4.1
-12.4
ATP-dependent sacrificial sulfur transferase LarE
compare
MMJJ
_RS07720
-4.1
-1.9
UPF0058 family protein
compare
MMJJ
_RS06270
-4.1
-8.6
dethiobiotin synthase
compare
MMJJ
_RS03115
-4.1
-8.0
sulfopyruvate decarboxylase subunit alpha
compare
MMJJ
_RS04595
-4.1
-5.9
hypothetical protein
compare
MMJJ
_RS03580
-4.1
-2.8
TIGR00303 family protein
compare
MMJJ
_RS04685
-4.1
-7.7
carbamoyltransferase HypF
compare
MMJJ
_RS07160
-4.0
-21.8
M20 family metallo-hydrolase
compare
MMJJ
_RS04475
-4.0
-6.4
3,4-dihydroxy-2-butanone-4-phosphate synthase
compare
MMJJ
_RS03895
-4.0
-3.7
hydrogenase expression/formation protein HypE
compare
MMJJ
_RS04200
-4.0
-7.0
triphosphoribosyl-dephospho-CoA synthase
compare
MMJJ
_RS06490
-4.0
-2.6
methanogenesis marker 2 protein
compare
MMJJ
_RS00065
-4.0
-10.6
4Fe-4S dicluster domain-containing protein
compare
MMJJ
_RS02200
-3.9
-7.9
chorismate pyruvate-lyase family protein
compare
MMJJ
_RS04800
-3.9
-4.6
2-phospho-L-lactate guanylyltransferase
compare
MMJJ
_RS07650
-3.9
-23.8
formate/nitrite transporter family protein
compare
MMJJ
_RS06930
-3.9
-3.2
type II methionyl aminopeptidase
compare
MMJJ
_RS03500
-3.9
-12.4
F420-dependent methylenetetrahydromethanopterin dehydrogenase
compare
MMJJ
_RS04155
-3.9
-4.6
hypothetical protein
compare
MMJJ
_RS07245
-3.8
-5.8
amidohydrolase family protein
compare
MMJJ
_RS01810
-3.8
-2.1
methyl coenzyme M reductase system, component A2
compare
MMJJ
_RS02045
-3.8
-3.0
molybdenum cofactor guanylyltransferase
compare
MMJJ
_RS03865
-3.8
-1.5
phosphoribosyl-AMP cyclohydrolase
compare
MMJJ
_RS06220
-3.8
-4.5
polyamine aminopropyltransferase
compare
MMJJ
_RS08000
-3.8
-8.8
HesA/MoeB/ThiF family protein
compare
MMJJ
_RS08065
-3.8
-3.7
precorrin-6Y C5,15-methyltransferase (decarboxylating) subunit CbiT
compare
MMJJ
_RS09135
-3.8
-12.4
archaeosine biosynthesis radical SAM protein RaSEA
compare
MMJJ
_RS03670
-3.8
-2.6
precorrin-2 C(20)-methyltransferase
compare
MMJJ
_RS06875
-3.8
-2.1
hypothetical protein
compare
MMJJ
_RS08095
-3.8
-3.6
cobyric acid synthase CobQ
compare
MMJJ
_RS04145
-3.8
-11.8
glutamate-1-semialdehyde 2,1-aminomutase
compare
MMJJ
_RS03200
-3.8
-2.0
uroporphyrinogen-III synthase
compare
MMJJ
_RS03170
-3.8
-9.0
DUF5612 domain-containing protein
compare
MMJJ
_RS00355
-3.8
-2.4
ribonuclease P protein component 4
compare
MMJJ
_RS07640
-3.7
-23.6
cache domain-containing protein
compare
MMJJ
_RS06700
-3.7
-6.9
L-seryl-tRNA(Sec) kinase
compare
MMJJ
_RS03110
-3.7
-2.5
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase
compare
MMJJ
_RS08020
-3.7
-10.6
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS06510
-3.7
-3.6
LL-diaminopimelate aminotransferase
compare
MMJJ
_RS05995
-3.7
-2.0
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS07350
-3.7
-3.4
4Fe-4S binding protein
compare
MMJJ
_RS08155
-3.6
-4.2
cobalt-precorrin-5B (C(1))-methyltransferase CbiD
compare
MMJJ
_RS03005
-3.6
-2.5
Ni-sirohydrochlorin a,c-diamide reductive cyclase catalytic subunit
compare
MMJJ
_RS07635
-3.6
-13.9
response regulator transcription factor
compare
MMJJ
_RS08840
-3.6
-4.8
calcium/sodium antiporter
compare
MMJJ
_RS03055
-3.6
-3.1
hypothetical protein
compare
MMJJ
_RS06485
-3.6
-2.4
phosphoglycerate kinase
compare
MMJJ
_RS07950
-3.6
-2.3
4Fe-4S binding protein
compare
MMJJ
_RS01935
-3.6
-4.7
O-phosphoseryl-tRNA(Sec) selenium transferase
compare
MMJJ
_RS00570
-3.5
-1.4
ribonuclease P
compare
MMJJ
_RS04995
-3.5
-4.7
Tfx family DNA-binding protein
compare
MMJJ
_RS07725
-3.5
-7.8
DNA primase DnaG
compare
MMJJ
_RS07470
-3.5
-2.3
50S ribosome-binding GTPase
compare
MMJJ
_RS06010
-3.5
-8.3
hypothetical protein
compare
MMJJ
_RS06180
-3.4
-2.4
tryptophan--tRNA ligase
compare
MMJJ
_RS06040
-3.4
-3.3
NADH-quinone oxidoreductase subunit H
compare
MMJJ
_RS08535
-3.4
-3.8
NOL1/NOP2/sun family putative RNA methylase
compare
MMJJ
_RS05190
-3.4
-8.6
gamma carbonic anhydrase family protein
compare
MMJJ
_RS05070
-3.4
-1.8
DNA primase catalytic subunit PriS
compare
MMJJ
_RS09190
-3.4
-1.9
tryptophan synthase subunit beta
compare
MMJJ
_RS03490
-3.4
-3.0
ribonuclease VapC
compare
MMJJ
_RS06695
-3.4
-2.1
amidohydrolase
compare
MMJJ
_RS00125
-3.4
-2.9
KEOPS complex subunit Cgi121
compare
MMJJ
_RS04970
-3.3
-1.6
DUF655 domain-containing protein
compare
MMJJ
_RS00080
-3.3
-14.3
DUF166 domain-containing protein
compare
MMJJ
_RS04700
-3.3
-6.8
deoxyhypusine synthase
compare
MMJJ
_RS01600
-3.3
-2.1
radical SAM protein
compare
MMJJ
_RS08330
-3.3
-3.7
SufD family Fe-S cluster assembly protein
compare
MMJJ
_RS00560
-3.3
-3.8
homoisocitrate dehydrogenase
compare
MMJJ
_RS06715
-3.3
-10.9
lactaldehyde dehydrogenase
compare
MMJJ
_RS03150
-3.3
-7.0
2-phospho-L-lactate transferase
compare
MMJJ
_RS03270
-3.3
-2.2
ribosome biogenesis/translation initiation ATPase RLI
compare
MMJJ
_RS07785
-3.2
-2.1
fumarate reductase subunit A
compare
MMJJ
_RS06625
-3.2
-1.5
pyruvate synthase subunit PorB
compare
MMJJ
_RS08850
-3.2
-1.9
succinate dehydrogenase/fumarate reductase iron-sulfur subunit
compare
MMJJ
_RS05490
-3.2
-2.1
imidazole glycerol phosphate synthase subunit HisF
compare
MMJJ
_RS00205
-3.1
-6.5
adenosylcobinamide-phosphate synthase CbiB
compare
MMJJ
_RS06110
-3.1
-1.8
bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC
compare
MMJJ
_RS03965
-3.1
-2.1
DNA-directed RNA polymerase subunit L
compare
MMJJ
_RS08010
-3.1
-8.2
phosphoadenosine phosphosulfate reductase family protein
compare
MMJJ
_RS05810
-3.1
-3.7
precorrin-4 C(11)-methyltransferase
compare
MMJJ
_RS04975
-3.1
-1.7
glycosyltransferase family 4 protein
compare
MMJJ
_RS03190
-3.1
-2.1
phosphopyruvate hydratase
compare
MMJJ
_RS06390
-3.1
-1.5
NADPH-dependent F420 reductase
compare
MMJJ
_RS06840
-3.1
-2.1
nickel-dependent hydrogenase large subunit
compare
MMJJ
_RS01360
-3.1
-1.8
UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
compare
MMJJ
_RS03295
-3.1
-14.5
PHP domain-containing protein
compare
MMJJ
_RS03875
-3.1
-4.2
CBS domain-containing protein
compare
MMJJ
_RS04790
-3.1
-4.7
biotin--[acetyl-CoA-carboxylase] ligase
compare
MMJJ
_RS03060
-3.0
-3.9
methanogenesis marker 7 protein
compare
MMJJ
_RS08320
-3.0
-2.2
CDP-diacylglycerol--serine O-phosphatidyltransferase
compare
MMJJ
_RS05720
-3.0
-1.9
glutamine--fructose-6-phosphate transaminase (isomerizing)
compare
MMJJ
_RS00270
-3.0
-2.8
adenosylcobinamide-GDP ribazoletransferase
compare
MMJJ
_RS00475
-3.0
-1.9
bifunctional ornithine acetyltransferase/N-acetylglutamate synthase
compare
MMJJ
_RS04650
-3.0
-6.9
nitrogenase iron protein
compare
MMJJ
_RS02935
-3.0
-3.1
DNA-directed RNA polymerase subunit E''
compare
MMJJ
_RS03760
-3.0
-3.4
hydrogenase maturation nickel metallochaperone HypA
compare
MMJJ
_RS05930
-3.0
-1.6
cell division protein SepF
compare
MMJJ
_RS03310
-3.0
-3.9
hypothetical protein
compare
MMJJ
_RS07430
-2.9
-3.7
ribonuclease VapC
compare
MMJJ
_RS02090
-2.9
-4.7
tyramine--L-glutamate ligase
compare
MMJJ
_RS07155
-2.9
-11.7
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMJJ
_RS06050
-2.9
-9.3
molybdopterin molybdotransferase MoeA
compare
MMJJ
_RS03095
-2.9
-1.7
bifunctional N(6)-L-threonylcarbamoyladenine synthase/serine/threonine protein kinase
compare
MMJJ
_RS06255
-2.9
-6.0
tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3
compare
MMJJ
_RS05415
-2.9
-1.6
hypothetical protein
compare
MMJJ
_RS04150
-2.9
-2.7
DUF5379 domain-containing protein
compare
MMJJ
_RS05260
-2.9
-6.1
ATP-grasp domain-containing protein
compare
MMJJ
_RS05540
-2.9
-19.1
LysR family transcriptional regulator
compare
MMJJ
_RS00215
-2.9
-1.7
CCA tRNA nucleotidyltransferase
compare
MMJJ
_RS01860
-2.8
-14.8
tRNA guanosine(15) transglycosylase TgtA
compare
MMJJ
_RS00360
-2.8
-2.5
adenosylhomocysteinase
compare
MMJJ
_RS01415
-2.8
-2.3
beta-CASP ribonuclease aCPSF1
compare
MMJJ
_RS03615
-2.8
-2.3
cobalt-precorrin-8 methylmutase
compare
MMJJ
_RS06805
-2.8
-2.5
monovalent cation/H+ antiporter subunit E
compare
MMJJ
_RS03125
-2.7
-5.1
GMC oxidoreductase
compare
MMJJ
_RS08250
-2.7
-6.7
hydrogenase maturation peptidase HycI
compare
MMJJ
_RS01880
-2.7
-2.9
RlmE family RNA methyltransferase
compare
MMJJ
_RS04980
-2.7
-5.2
bifunctional precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase
compare
MMJJ
_RS07265
-2.7
-13.2
tRNA (adenine-N1)-methyltransferase
compare
MMJJ
_RS06250
-2.7
-1.7
nicotinamide-nucleotide adenylyltransferase
compare
MMJJ
_RS06015
-2.7
-12.9
Na(+)/H(+) antiporter subunit B
compare
MMJJ
_RS09375
-2.7
-1.4
hypothetical protein
compare
MMJJ
_RS02190
-2.7
-12.3
molybdopterin biosynthesis protein
compare
MMJJ
_RS08055
-2.7
-7.2
methanogenesis marker 14 protein
compare
MMJJ
_RS06030
-2.6
-5.6
4Fe-4S binding protein
compare
MMJJ
_RS06175
-2.6
-2.2
DUF1743 domain-containing protein
compare
MMJJ
_RS04730
-2.6
-1.7
tyrosine decarboxylase MfnA
compare
MMJJ
_RS09175
-2.6
-0.9
anthranilate synthase component I
compare
MMJJ
_RS00425
-2.6
-4.6
hypothetical protein
compare
MMJJ
_RS06215
-2.6
-5.5
agmatinase
compare
MMJJ
_RS05375
-2.6
-14.0
radical SAM protein
compare
MMJJ
_RS05380
-2.6
-1.2
hypothetical protein
compare
MMJJ
_RS06910
-2.6
-1.5
energy-converting NiFe hydrogenase A subunit EhaA
compare
MMJJ
_RS04125
-2.6
-12.1
tRNA (guanine(10)-N(2))-dimethyltransferase
compare
MMJJ
_RS06000
-2.6
-5.4
cation:proton antiporter subunit C
compare
MMJJ
_RS06025
-2.6
-15.9
4Fe-4S binding protein
compare
MMJJ
_RS03660
-2.6
-3.6
DUF447 family protein
compare
MMJJ
_RS07355
-2.5
-4.2
MoaD/ThiS family protein
compare
MMJJ
_RS08405
-2.5
-13.2
nickel-dependent hydrogenase large subunit
compare
MMJJ
_RS06905
-2.5
-2.3
hypothetical protein
compare
MMJJ
_RS06020
-2.5
-6.1
hypothetical protein
compare
MMJJ
_RS04520
-2.5
-6.1
coenzyme F430 synthase
compare
MMJJ
_RS06035
-2.5
-8.4
NADH-quinone oxidoreductase subunit B family protein
compare
MMJJ
_RS05330
-2.5
-2.1
DNA polymerase II large subunit
compare
MMJJ
_RS05950
-2.5
-3.2
bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase
compare
MMJJ
_RS05590
-2.5
-1.2
homoserine dehydrogenase
compare
MMJJ
_RS07415
-2.5
-2.4
polyprenyl diphosphate synthase
compare
MMJJ
_RS04675
-2.5
-7.3
thiamine pyrophosphate-binding protein
compare
MMJJ
_RS06750
-2.5
-1.3
homoaconitase large subunit
compare
MMJJ
_RS00550
-2.5
-8.0
AIR synthase-related protein
compare
MMJJ
_RS00385
-2.5
-10.2
TIGR00454 family protein
compare
MMJJ
_RS07410
-2.5
-3.7
methanogenesis marker protein Mmp4/MtxX
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis JJ in rich t2 experiments