Experiment set1IT036 for Pseudomonas fluorescens FW300-N2E2

Compare to:

LB with Cobalt chloride hexahydrate 0.16 mM

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_4369 -3.7 -3.6 Exodeoxyribonuclease III (EC 3.1.11.2) compare
Pf6N2E2_4059 -3.5 -2.2 DNA-binding protein HU-alpha compare
Pf6N2E2_5679 -2.8 -7.3 hypothetical protein compare
Pf6N2E2_3908 -2.4 -8.9 Glutamate--cysteine ligase (EC 6.3.2.2) compare
Pf6N2E2_4092 -2.1 -4.8 FIG00954395: hypothetical protein compare
Pf6N2E2_3847 -2.1 -5.3 FIG001341: Probable Fe(2+)-trafficking protein YggX compare
Pf6N2E2_4071 -2.1 -6.8 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_563 -2.1 -8.0 Serine transporter conserved
Pf6N2E2_5671 -2.0 -4.7 Succinylglutamate desuccinylase (EC 3.5.1.96) compare
Pf6N2E2_5111 -2.0 -3.3 FKBP-type peptidyl-prolyl cis-trans isomerase SlpA (EC 5.2.1.8) compare
Pf6N2E2_2129 -1.9 -5.8 Predicted dye-decolorizing peroxidase (DyP), YfeX-like subgroup compare
Pf6N2E2_4612 -1.9 -5.5 Glutathione synthetase (EC 6.3.2.3) compare
Pf6N2E2_4120 -1.8 -11.0 Trk system potassium uptake protein TrkA compare
Pf6N2E2_3770 -1.7 -3.2 ATP-dependent hsl protease ATP-binding subunit HslU compare
Pf6N2E2_4352 -1.6 -3.3 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf6N2E2_2201 -1.5 -3.5 Transmembrane regulator protein PrtR compare
Pf6N2E2_5534 -1.5 -5.8 FIG000859: hypothetical protein YebC compare
Pf6N2E2_2794 -1.5 -2.5 putative membrane protein compare
Pf6N2E2_4615 -1.5 -2.2 type IV pili signal transduction protein PilI compare
Pf6N2E2_3661 -1.5 -4.4 hypothetical protein compare
Pf6N2E2_5430 -1.4 -7.1 Transglycosylase, Slt family compare
Pf6N2E2_4416 -1.4 -3.6 Tyrosine recombinase XerC compare
Pf6N2E2_3659 -1.4 -5.1 Protein fixF compare
Pf6N2E2_4673 -1.4 -4.3 ATP-dependent 23S rRNA helicase DbpA compare
Pf6N2E2_5520 -1.3 -5.8 Sensory box histidine kinase compare
Pf6N2E2_4422 -1.3 -3.4 Frataxin homolog CyaY, facilitates iron supply for heme A synthesis or Fe-S cluster assembly compare
Pf6N2E2_2261 -1.3 -6.2 VacJ-like lipoprotein precursor compare
Pf6N2E2_2634 -1.3 -7.9 Potassium uptake protein TrkH compare
Pf6N2E2_4614 -1.3 -3.7 twitching motility protein PilH compare
Pf6N2E2_1087 -1.3 -6.4 Iron siderophore sensor protein compare
Pf6N2E2_546 -1.3 -1.5 FIG00966904: hypothetical protein compare
Pf6N2E2_5640 -1.3 -2.1 FIG00955597: hypothetical protein compare
Pf6N2E2_4391 -1.2 -6.1 D-amino acid dehydrogenase small subunit (EC 1.4.99.1) compare
Pf6N2E2_5331 -1.2 -5.1 ATPase, AFG1 family compare
Pf6N2E2_4733 -1.2 -2.1 hypothetical protein compare
Pf6N2E2_5499 -1.1 -1.4 hypothetical protein compare
Pf6N2E2_2514 -1.1 -3.5 regulator of length of O-antigen component of lipopolysaccharide chains compare
Pf6N2E2_1917 -1.1 -3.0 hypothetical protein compare
Pf6N2E2_6140 -1.1 -1.3 Large Subunit Ribosomal RNA; lsuRNA; LSU rRNA compare
Pf6N2E2_3920 -1.0 -7.8 Cystine ABC transporter, permease protein compare
Pf6N2E2_2825 -1.0 -3.3 RND efflux system, outer membrane lipoprotein CmeC compare
Pf6N2E2_3829 -1.0 -3.2 Protein export cytoplasm chaperone protein (SecB, maintains protein to be exported in unfolded state) compare
Pf6N2E2_3252 -1.0 -4.5 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_2447 -1.0 -5.5 Probable protease htpX homolog (EC 3.4.24.-) compare
Pf6N2E2_5714 -1.0 -2.2 Flavoprotein WrbA compare
Pf6N2E2_3919 -1.0 -5.8 Cystine ABC transporter, periplasmic cystine-binding protein FliY compare
Pf6N2E2_3179 -1.0 -1.5 FIG021952: putative membrane protein compare
Pf6N2E2_5320 -1.0 -5.5 Cytochrome O ubiquinol oxidase subunit IV (EC 1.10.3.-) compare
Pf6N2E2_2156 -1.0 -2.5 Putative polyketide synthase (Fragment) compare
Pf6N2E2_2518 -1.0 -1.6 Cyclohexadienyl dehydrogenase (EC 1.3.1.12)(EC 1.3.1.43) / 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19) compare
Pf6N2E2_4453 -0.9 -8.0 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_4636 -0.9 -5.8 periplasmic binding protein, putative compare
Pf6N2E2_3586 -0.9 -4.9 NAD synthetase (EC 6.3.1.5) compare
Pf6N2E2_5816 -0.9 -2.0 Smr domain protein compare
Pf6N2E2_1634 -0.9 -4.1 ABC-type Fe3+-siderophore transport system, permease component compare
Pf6N2E2_5527 -0.9 -1.6 Cold shock protein CspC compare
Pf6N2E2_3258 -0.9 -3.0 Uncharacterized ABC transporter, periplasmic component YrbD compare
Pf6N2E2_1625 -0.9 -1.9 Ferric reductase (1.6.99.14) compare
Pf6N2E2_3351 -0.9 -3.2 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
Pf6N2E2_5155 -0.9 -2.5 Poly(A) polymerase (EC 2.7.7.19) compare
Pf6N2E2_1636 -0.9 -4.7 Ferrichrome-iron receptor compare
Pf6N2E2_3257 -0.9 -3.1 Uncharacterized ABC transporter, auxiliary component YrbC compare
Pf6N2E2_4162 -0.9 -2.3 DNA polymerase I (EC 2.7.7.7) compare
Pf6N2E2_170 -0.9 -1.0 lipoprotein, putative compare
Pf6N2E2_2549 -0.9 -1.9 hypothetical protein compare
Pf6N2E2_4618 -0.8 -2.8 Chemotaxis signal transduction protein compare
Pf6N2E2_3658 -0.8 -4.6 Lipid A core - O-antigen ligase and related enzymes compare
Pf6N2E2_4276 -0.8 -3.3 Phosphogluconate repressor HexR, RpiR family compare
Pf6N2E2_5319 -0.8 -4.6 Cytochrome O ubiquinol oxidase subunit III (EC 1.10.3.-) compare
Pf6N2E2_3607 -0.8 -4.8 3'-to-5' exoribonuclease RNase R compare
Pf6N2E2_4459 -0.8 -1.4 Transcriptional regulator, GntR family compare
Pf6N2E2_623 -0.8 -1.2 FIG00954674: hypothetical protein compare
Pf6N2E2_5820 -0.8 -2.3 FIG00957914: hypothetical protein compare
Pf6N2E2_1606 -0.8 -3.6 Carboxynorspermidine decarboxylase, putative (EC 4.1.1.-) compare
Pf6N2E2_2340 -0.8 -3.5 Transcriptional regulator, GntR family compare
Pf6N2E2_5318 -0.8 -7.1 Cytochrome O ubiquinol oxidase subunit I (EC 1.10.3.-) compare
Pf6N2E2_4987 -0.8 -1.1 MaoC-like domain protein compare
Pf6N2E2_3255 -0.8 -3.3 YrbA protein compare
Pf6N2E2_2018 -0.8 -1.8 hypothetical protein compare
Pf6N2E2_4091 -0.8 -4.7 Oligopeptidase A (EC 3.4.24.70) compare
Pf6N2E2_2282 -0.8 -2.7 Predicted transcriptional regulator for fatty acid degradation FadQ, TetR family compare
Pf6N2E2_5956 -0.8 -3.5 FIG004453: protein YceG like compare
Pf6N2E2_1450 -0.8 -1.8 FIG00960438: hypothetical protein compare
Pf6N2E2_3830 -0.8 -3.4 Glutaredoxin 3 (Grx3) compare
Pf6N2E2_3655 -0.8 -6.1 Hypothetical protein FIG015671 in large core OS assembly cluster compare
Pf6N2E2_3984 -0.8 -5.5 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_5668 -0.7 -3.5 Succinylglutamic semialdehyde dehydrogenase (EC 1.2.1.71) compare
Pf6N2E2_5317 -0.7 -5.5 Cytochrome O ubiquinol oxidase subunit II (EC 1.10.3.-) compare
Pf6N2E2_3537 -0.7 -2.4 Cobalt-precorrin-6x reductase (EC 1.3.1.54) compare
Pf6N2E2_4155 -0.7 -4.5 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) compare
Pf6N2E2_6071 -0.7 -2.9 FIG139991: Putative thiamine pyrophosphate-requiring enzyme compare
Pf6N2E2_2371 -0.7 -1.9 Type III secretion outermembrane contact sensing protein (YopN,Yop4b,LcrE) compare
Pf6N2E2_4077 -0.7 -1.6 cytosolic long-chain acyl-CoA thioester hydrolase family protein compare
Pf6N2E2_3782 -0.7 -2.3 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_445 -0.7 -3.4 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) compare
Pf6N2E2_504 -0.7 -2.0 DNA-binding response regulator compare
Pf6N2E2_2852 -0.7 -4.4 GGDEF domain/EAL domain protein compare
Pf6N2E2_5573 -0.7 -2.3 Glycerol-3-phosphate regulon repressor, DeoR family compare
Pf6N2E2_2753 -0.7 -1.3 HtrA protease/chaperone protein compare
Pf6N2E2_1352 -0.7 -2.0 Cation transport ATPase compare
Pf6N2E2_5001 -0.7 -1.1 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) compare
Pf6N2E2_1492 -0.7 -2.2 No significant database matches compare
Pf6N2E2_5300 -0.7 -5.0 Transcriptional regulator, GntR family domain / Aspartate aminotransferase (EC 2.6.1.1) compare
Pf6N2E2_2912 -0.7 -1.4 FIG00954094: hypothetical protein compare
Pf6N2E2_2941 -0.7 -3.8 Esterase A compare
Pf6N2E2_5262 -0.7 -2.2 FKBP-type peptidyl-prolyl cis-trans isomerase SlyD (EC 5.2.1.8) compare
Pf6N2E2_558 -0.7 -2.1 Uncharacterized protein ImpJ/VasE compare
Pf6N2E2_5669 -0.7 -3.3 Succinylarginine dihydrolase (EC 3.5.3.23) compare
Pf6N2E2_2068 -0.7 -4.3 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) compare
Pf6N2E2_5321 -0.7 -4.6 Heme O synthase, protoheme IX farnesyltransferase (EC 2.5.1.-) COX10-CtaB compare
Pf6N2E2_1173 -0.7 -1.8 hypothetical protein compare
Pf6N2E2_1392 -0.7 -3.2 sensor histidine kinase compare
Pf6N2E2_2510 -0.7 -2.1 Lipid carrier : UDP-N-acetylgalactosaminyltransferase (EC 2.4.1.-) / Alpha-1,3-N-acetylgalactosamine transferase PglA (EC 2.4.1.-); Putative glycosyltransferase compare
Pf6N2E2_3460 -0.7 -1.3 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_1385 -0.7 -2.0 FIG00956261: hypothetical protein compare
Pf6N2E2_1806 -0.7 -1.0 hypothetical protein compare
Pf6N2E2_1870 -0.7 -1.4 hypothetical protein compare
Pf6N2E2_5756 -0.7 -1.6 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_1281 -0.7 -2.1 ATPase involved in DNA repair compare
Pf6N2E2_2544 -0.7 -2.8 Deblocking aminopeptidase (EC 3.4.11.-) @ Cyanophycinase 2 (EC 3.4.15.6) compare
Pf6N2E2_1287 -0.7 -2.4 Mobile element protein compare
Pf6N2E2_562 -0.6 -2.5 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_3100 -0.6 -1.8 FIG00953063: hypothetical protein compare
Pf6N2E2_561 -0.6 -2.1 Uncharacterized protein ImpA compare
Pf6N2E2_1293 -0.6 -1.4 COG2879, Hypothetical small protein yjiX compare
Pf6N2E2_37 -0.6 -2.3 6-carboxytetrahydropterin synthase (EC 4.1.2.50) @ Queuosine biosynthesis QueD, PTPS-I compare
Pf6N2E2_3872 -0.6 -2.4 hypothetical protein compare
Pf6N2E2_2064 -0.6 -2.5 Cobalt-precorrin-3b C17-methyltransferase compare
Pf6N2E2_1778 -0.6 -2.3 Positive regulator of CheA protein activity (CheW) compare
Pf6N2E2_4206 -0.6 -1.4 Chromosome (plasmid) partitioning protein ParB compare
Pf6N2E2_726 -0.6 -2.9 Nitrate/nitrite sensor protein (EC 2.7.3.-) compare
Pf6N2E2_6099 -0.6 -1.0 tRNA-Glu-TTC compare
Pf6N2E2_2506 -0.6 -4.9 nucleotide sugar epimerase/dehydratase WbpM compare
Pf6N2E2_2755 -0.6 -1.1 Sigma factor RpoE negative regulatory protein RseA compare
Pf6N2E2_4585 -0.6 -4.7 Cell division protein FtsX compare
Pf6N2E2_1839 -0.6 -2.1 2-hydroxycyclohexanecarboxyl-CoA dehydrogenase (EC 1.1.1.-) compare
Pf6N2E2_2171 -0.6 -3.6 Rhodanese-related sulfurtransferase compare
Pf6N2E2_4599 -0.6 -2.4 Integral membrane protein YggT, involved in response to extracytoplasmic stress (osmotic shock) compare
Pf6N2E2_4999 -0.6 -3.5 Membrane-bound lytic murein transglycosylase B precursor (EC 3.2.1.-) compare
Pf6N2E2_4797 -0.6 -1.3 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_2938 -0.6 -3.1 Outer membrane lipoprotein compare
Pf6N2E2_2258 -0.6 -3.7 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_2251 -0.6 -1.8 NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3) conserved
Pf6N2E2_2722 -0.6 -2.1 FIG00954807: hypothetical protein compare
Pf6N2E2_1983 -0.6 -1.5 hypothetical protein compare
Pf6N2E2_4617 -0.6 -5.1 Signal transduction histidine kinase CheA (EC 2.7.3.-) compare
Pf6N2E2_3079 -0.6 -2.8 Cysteine desulfurase CsdA-CsdE (EC 2.8.1.7), main protein CsdA compare
Pf6N2E2_1147 -0.6 -1.1 Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) compare
Pf6N2E2_2487 -0.6 -0.8 FIG00956090: hypothetical protein compare
Pf6N2E2_3533 -0.6 -2.4 Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) compare
Pf6N2E2_5086 -0.6 -1.0 hypothetical protein compare
Pf6N2E2_5505 -0.6 -1.7 hypothetical protein compare
Pf6N2E2_2293 -0.6 -2.5 COG0488: ATPase components of ABC transporters with duplicated ATPase domains compare
Pf6N2E2_5955 -0.6 -2.1 Aminodeoxychorismate lyase (EC 4.1.3.38) compare
Pf6N2E2_2274 -0.6 -2.0 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) compare
Pf6N2E2_434 -0.6 -1.0 hypothetical protein compare
Pf6N2E2_1635 -0.6 -1.6 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components compare
Pf6N2E2_319 -0.6 -1.9 DUF1850 domain-containing protein compare
Pf6N2E2_4594 -0.6 -1.5 Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) compare
Pf6N2E2_75 -0.6 -2.0 Colicin V production protein compare
Pf6N2E2_5990 -0.6 -0.9 Translation initiation factor 2 (IF-2; GTPase) compare
Pf6N2E2_3081 -0.6 -2.5 HesA/MoeB/ThiF family protein related to EC-YgdL compare
Pf6N2E2_2223 -0.6 -1.1 hypothetical protein compare
Pf6N2E2_133 -0.6 -1.1 hypothetical protein compare
Pf6N2E2_5013 -0.6 -1.6 Putative membrane protein compare
Pf6N2E2_3326 -0.6 -0.8 hypothetical protein compare
Pf6N2E2_451 -0.5 -1.2 transcriptional regulator MvaT, P16 subunit, putative compare
Pf6N2E2_1176 -0.5 -2.4 Mll2356 protein compare
Pf6N2E2_1199 -0.5 -2.0 hypothetical protein compare
Pf6N2E2_358 -0.5 -1.5 Haloacid dehalogenase, type II compare
Pf6N2E2_3656 -0.5 -2.5 Probable transcription regulator Mig-14 compare
Pf6N2E2_180 -0.5 -2.2 Transcriptional regulator, MerR family compare
Pf6N2E2_4187 -0.5 -1.6 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_5245 -0.5 -2.8 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_5848 -0.5 -1.6 small component of pyruvate transporter (yjcH-like) (from data) compare
Pf6N2E2_2188 -0.5 -1.9 Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family compare
Pf6N2E2_2387 -0.5 -1.8 Ribonuclease E inhibitor RraA compare
Pf6N2E2_5739 -0.5 -1.0 Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family compare
Pf6N2E2_1667 -0.5 -1.5 Fumarylacetoacetate hydrolase family protein compare
Pf6N2E2_3610 -0.5 -2.4 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_1611 -0.5 -1.5 Phosphonate ABC transporter permease protein phnE2 (TC 3.A.1.9.1) compare
Pf6N2E2_3260 -0.5 -2.3 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
Pf6N2E2_161 -0.5 -1.5 Ribose ABC transport system, periplasmic ribose-binding protein RbsB (TC 3.A.1.2.1) compare
Pf6N2E2_2708 -0.5 -2.6 Lactam utilization protein LamB compare
Pf6N2E2_1386 -0.5 -2.3 amino acid ABC transporter, periplasmic substrate-binding protein compare
Pf6N2E2_555 -0.5 -1.1 Uncharacterized protein ImpB compare
Pf6N2E2_621 -0.5 -2.4 TPR domain protein in aerotolerance operon compare
Pf6N2E2_2428 -0.5 -1.3 Thiol-disulfide isomerase and thioredoxins compare
Pf6N2E2_5150 -0.5 -2.3 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf6N2E2_2281 -0.5 -0.9 Beta N-acetyl-glucosaminidase (EC 3.2.1.52) compare
Pf6N2E2_2065 -0.5 -1.6 Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) compare
Pf6N2E2_1875 -0.5 -1.7 Protoporphyrinogen oxidase (EC 1.3.3.4) compare
Pf6N2E2_1276 -0.5 -2.5 FIG00958406: hypothetical protein compare
Pf6N2E2_423 -0.5 -0.8 Putative phosphatase YfbT compare
Pf6N2E2_384 -0.5 -1.1 Glycine cleavage system transcriptional activator compare
Pf6N2E2_339 -0.5 -1.4 Glutathione-regulated potassium-efflux system protein KefC compare
Pf6N2E2_237 -0.5 -1.3 hypothetical protein compare
Pf6N2E2_3198 -0.5 -1.2 tRNA-guanine transglycosylase (EC 2.4.2.29) compare
Pf6N2E2_2887 -0.5 -2.2 Aldose 1-epimerase compare
Pf6N2E2_4928 -0.5 -0.9 Permeases of the major facilitator superfamily compare


Specific Phenotypes

For 2 genes in this experiment

For stress Cobalt chloride hexahydrate in Pseudomonas fluorescens FW300-N2E2

For stress Cobalt chloride hexahydrate across organisms