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Experiment set1IT036 for
Methanococcus maripaludis JJ
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Formate McCas, 2.5g/L bicarb, 200 mM MOPs, 20 psi N2CO2, SO4 FREE
200 most important genes:
gene
name
fitness
t score
description
MMJJ
_RS07660
-6.1
-8.4
carbonic anhydrase
compare
MMJJ
_RS08855
-5.9
-5.4
cyclic pyranopterin monophosphate synthase MoaC
compare
MMJJ
_RS07670
-5.7
-19.8
Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain
compare
MMJJ
_RS08005
-5.7
-17.9
formate dehydrogenase accessory sulfurtransferase FdhD
compare
MMJJ
_RS07665
-5.6
-28.6
formate dehydrogenase subunit alpha
compare
MMJJ
_RS06600
-5.2
-3.4
DUF555 domain-containing protein
compare
MMJJ
_RS02055
-5.2
-13.0
GTP 3',8-cyclase MoaA
compare
MMJJ
_RS03065
-5.2
-16.0
CBS domain-containing protein
compare
MMJJ
_RS05155
-5.1
-6.0
5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH
compare
MMJJ
_RS07995
-5.0
-9.0
molybdenum cofactor biosynthesis protein MoaE
compare
MMJJ
_RS00645
-5.0
-6.9
adenosylmethionine--8-amino-7-oxononanoate transaminase
compare
MMJJ
_RS07655
-5.0
-14.8
hypothetical protein
compare
MMJJ
_RS06860
-5.0
-3.4
hypothetical protein
compare
MMJJ
_RS00050
-5.0
-11.9
AAA family ATPase
compare
MMJJ
_RS07650
-4.9
-23.0
formate/nitrite transporter family protein
compare
MMJJ
_RS04475
-4.8
-5.6
3,4-dihydroxy-2-butanone-4-phosphate synthase
compare
MMJJ
_RS04485
-4.7
-10.8
riboflavin synthase
compare
MMJJ
_RS00580
-4.7
-2.3
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG
compare
MMJJ
_RS01810
-4.6
-2.3
methyl coenzyme M reductase system, component A2
compare
MMJJ
_RS06725
-4.6
-8.9
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMJJ
_RS06155
-4.6
-3.1
phosphatidylglycerophosphatase A
compare
MMJJ
_RS00055
-4.6
-12.7
CO dehydrogenase/acetyl-CoA synthase subunit delta
compare
MMJJ
_RS00040
-4.6
-12.0
CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon
compare
MMJJ
_RS07635
-4.5
-16.3
response regulator transcription factor
compare
MMJJ
_RS05535
-4.5
-13.5
hypothetical protein
compare
MMJJ
_RS04595
-4.5
-7.4
hypothetical protein
compare
MMJJ
_RS06270
-4.5
-6.8
dethiobiotin synthase
compare
MMJJ
_RS02935
-4.5
-3.8
DNA-directed RNA polymerase subunit E''
compare
MMJJ
_RS03115
-4.5
-7.8
sulfopyruvate decarboxylase subunit alpha
compare
MMJJ
_RS06510
-4.4
-3.0
LL-diaminopimelate aminotransferase
compare
MMJJ
_RS03620
-4.4
-3.0
DUF2097 domain-containing protein
compare
MMJJ
_RS04200
-4.4
-5.2
triphosphoribosyl-dephospho-CoA synthase
compare
MMJJ
_RS00275
-4.4
-2.8
coenzyme F420-0:L-glutamate ligase
compare
MMJJ
_RS00450
-4.4
-2.5
DUF126 domain-containing protein
compare
MMJJ
_RS00060
-4.3
-19.7
acetyl-CoA decarbonylase/synthase complex subunit gamma
compare
MMJJ
_RS08080
-4.3
-8.7
TIGR00300 family protein
compare
MMJJ
_RS00045
-4.3
-18.2
CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta
compare
MMJJ
_RS02920
-4.3
-2.5
30S ribosomal protein S27ae
compare
MMJJ
_RS07975
-4.3
-13.4
ATP-dependent sacrificial sulfur transferase LarE
compare
MMJJ
_RS08020
-4.2
-9.6
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS07640
-4.2
-24.0
cache domain-containing protein
compare
MMJJ
_RS03920
-4.2
-16.2
nickel pincer cofactor biosynthesis protein LarC
compare
MMJJ
_RS05575
-4.2
-4.1
2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase
compare
MMJJ
_RS06915
-4.2
-18.1
helix-turn-helix domain-containing protein
compare
MMJJ
_RS06260
-4.2
-10.3
6-carboxyhexanoate--CoA ligase
compare
MMJJ
_RS00035
-4.2
-19.6
CO dehydrogenase/acetyl-CoA synthase complex subunit alpha
compare
MMJJ
_RS00065
-4.2
-11.1
4Fe-4S dicluster domain-containing protein
compare
MMJJ
_RS06240
-4.1
-2.8
dihydropteroate synthase-like protein
compare
MMJJ
_RS08065
-4.1
-3.5
precorrin-6Y C5,15-methyltransferase (decarboxylating) subunit CbiT
compare
MMJJ
_RS01935
-4.1
-2.8
O-phosphoseryl-tRNA(Sec) selenium transferase
compare
MMJJ
_RS02045
-4.1
-2.8
molybdenum cofactor guanylyltransferase
compare
MMJJ
_RS06930
-4.1
-2.8
type II methionyl aminopeptidase
compare
MMJJ
_RS07350
-4.1
-2.8
4Fe-4S binding protein
compare
MMJJ
_RS06855
-4.0
-2.0
DUF2104 domain-containing protein
compare
MMJJ
_RS08035
-4.0
-8.8
cobalt-precorrin-7 (C(5))-methyltransferase
compare
MMJJ
_RS04685
-4.0
-6.6
carbamoyltransferase HypF
compare
MMJJ
_RS07160
-4.0
-20.6
M20 family metallo-hydrolase
compare
MMJJ
_RS07720
-4.0
-2.2
UPF0058 family protein
compare
MMJJ
_RS08625
-4.0
-2.7
magnesium/cobalt transporter CorA
compare
MMJJ
_RS06220
-4.0
-2.7
polyamine aminopropyltransferase
compare
MMJJ
_RS01750
-3.9
-2.7
ferrous iron transport protein A
compare
MMJJ
_RS04155
-3.9
-2.7
hypothetical protein
compare
MMJJ
_RS06265
-3.9
-15.2
8-amino-7-oxononanoate synthase
compare
MMJJ
_RS05190
-3.8
-11.7
gamma carbonic anhydrase family protein
compare
MMJJ
_RS06490
-3.8
-2.6
methanogenesis marker 2 protein
compare
MMJJ
_RS08095
-3.8
-2.6
cobyric acid synthase CobQ
compare
MMJJ
_RS08000
-3.8
-10.0
HesA/MoeB/ThiF family protein
compare
MMJJ
_RS00075
-3.8
-14.5
AAA family ATPase
compare
MMJJ
_RS04800
-3.8
-4.4
2-phospho-L-lactate guanylyltransferase
compare
MMJJ
_RS05445
-3.8
-2.8
2-oxoacid:acceptor oxidoreductase subunit alpha
compare
MMJJ
_RS00935
-3.8
-16.4
nickel pincer cofactor biosynthesis protein LarB
compare
MMJJ
_RS07980
-3.8
-12.4
biotin synthase BioB
compare
MMJJ
_RS00205
-3.7
-4.4
adenosylcobinamide-phosphate synthase CbiB
compare
MMJJ
_RS05065
-3.7
-5.0
(4-{4-[2-(gamma-L- glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase
compare
MMJJ
_RS03865
-3.7
-1.8
phosphoribosyl-AMP cyclohydrolase
compare
MMJJ
_RS06050
-3.7
-11.5
molybdopterin molybdotransferase MoeA
compare
MMJJ
_RS08155
-3.7
-3.5
cobalt-precorrin-5B (C(1))-methyltransferase CbiD
compare
MMJJ
_RS03670
-3.7
-2.5
precorrin-2 C(20)-methyltransferase
compare
MMJJ
_RS00125
-3.7
-2.5
KEOPS complex subunit Cgi121
compare
MMJJ
_RS02200
-3.6
-7.7
chorismate pyruvate-lyase family protein
compare
MMJJ
_RS03200
-3.6
-2.3
uroporphyrinogen-III synthase
compare
MMJJ
_RS06875
-3.6
-2.4
hypothetical protein
compare
MMJJ
_RS08535
-3.6
-3.5
NOL1/NOP2/sun family putative RNA methylase
compare
MMJJ
_RS09375
-3.6
-1.8
hypothetical protein
compare
MMJJ
_RS07725
-3.6
-5.4
DNA primase DnaG
compare
MMJJ
_RS03270
-3.6
-2.1
ribosome biogenesis/translation initiation ATPase RLI
compare
MMJJ
_RS00355
-3.6
-2.4
ribonuclease P protein component 4
compare
MMJJ
_RS05995
-3.6
-2.3
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS03110
-3.5
-2.4
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase
compare
MMJJ
_RS03490
-3.5
-3.3
ribonuclease VapC
compare
MMJJ
_RS04145
-3.5
-10.4
glutamate-1-semialdehyde 2,1-aminomutase
compare
MMJJ
_RS01350
-3.5
-6.2
sodium:proton antiporter
compare
MMJJ
_RS06700
-3.5
-6.1
L-seryl-tRNA(Sec) kinase
compare
MMJJ
_RS04700
-3.5
-6.2
deoxyhypusine synthase
compare
MMJJ
_RS03500
-3.5
-10.1
F420-dependent methylenetetrahydromethanopterin dehydrogenase
compare
MMJJ
_RS03580
-3.5
-3.3
TIGR00303 family protein
compare
MMJJ
_RS08870
-3.5
-1.4
2-isopropylmalate synthase
compare
MMJJ
_RS07430
-3.5
-3.7
ribonuclease VapC
compare
MMJJ
_RS00080
-3.5
-17.1
DUF166 domain-containing protein
compare
MMJJ
_RS06485
-3.4
-2.3
phosphoglycerate kinase
compare
MMJJ
_RS07950
-3.4
-2.3
4Fe-4S binding protein
compare
MMJJ
_RS09135
-3.4
-11.2
archaeosine biosynthesis radical SAM protein RaSEA
compare
MMJJ
_RS06015
-3.4
-12.3
Na(+)/H(+) antiporter subunit B
compare
MMJJ
_RS03965
-3.4
-1.9
DNA-directed RNA polymerase subunit L
compare
MMJJ
_RS07355
-3.4
-6.6
MoaD/ThiS family protein
compare
MMJJ
_RS05935
-3.3
-2.1
Era-like GTP-binding protein
compare
MMJJ
_RS06375
-3.3
-4.9
UbiX family flavin prenyltransferase
compare
MMJJ
_RS06180
-3.3
-2.3
tryptophan--tRNA ligase
compare
MMJJ
_RS05540
-3.3
-20.5
LysR family transcriptional regulator
compare
MMJJ
_RS04520
-3.3
-4.9
coenzyme F430 synthase
compare
MMJJ
_RS03150
-3.3
-6.4
2-phospho-L-lactate transferase
compare
MMJJ
_RS06000
-3.3
-6.4
cation:proton antiporter subunit C
compare
MMJJ
_RS06715
-3.3
-9.7
lactaldehyde dehydrogenase
compare
MMJJ
_RS05070
-3.3
-2.1
DNA primase catalytic subunit PriS
compare
MMJJ
_RS04970
-3.2
-1.9
DUF655 domain-containing protein
compare
MMJJ
_RS07245
-3.2
-6.0
amidohydrolase family protein
compare
MMJJ
_RS06010
-3.2
-7.2
hypothetical protein
compare
MMJJ
_RS03295
-3.2
-14.0
PHP domain-containing protein
compare
MMJJ
_RS04650
-3.2
-5.9
nitrogenase iron protein
compare
MMJJ
_RS08250
-3.2
-5.6
hydrogenase maturation peptidase HycI
compare
MMJJ
_RS06695
-3.2
-2.2
amidohydrolase
compare
MMJJ
_RS00070
-3.2
-2.4
CooT family nickel-binding protein
compare
MMJJ
_RS05370
-3.2
-10.1
LysR family transcriptional regulator
compare
MMJJ
_RS01600
-3.1
-2.1
radical SAM protein
compare
MMJJ
_RS03310
-3.1
-3.0
hypothetical protein
compare
MMJJ
_RS00370
-3.1
-2.3
asparagine synthase (glutamine-hydrolyzing)
compare
MMJJ
_RS03060
-3.1
-4.0
methanogenesis marker 7 protein
compare
MMJJ
_RS07785
-3.1
-2.1
fumarate reductase subunit A
compare
MMJJ
_RS03170
-3.1
-8.5
DUF5612 domain-containing protein
compare
MMJJ
_RS08850
-3.1
-2.1
succinate dehydrogenase/fumarate reductase iron-sulfur subunit
compare
MMJJ
_RS06040
-3.1
-2.9
NADH-quinone oxidoreductase subunit H
compare
MMJJ
_RS06020
-3.1
-6.9
hypothetical protein
compare
MMJJ
_RS04050
-3.1
-2.1
dihydroneopterin aldolase family protein
compare
MMJJ
_RS05490
-3.1
-2.1
imidazole glycerol phosphate synthase subunit HisF
compare
MMJJ
_RS08840
-3.1
-4.1
calcium/sodium antiporter
compare
MMJJ
_RS03760
-3.1
-2.9
hydrogenase maturation nickel metallochaperone HypA
compare
MMJJ
_RS06625
-3.1
-1.7
pyruvate synthase subunit PorB
compare
MMJJ
_RS06255
-3.0
-5.0
tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3
compare
MMJJ
_RS02190
-3.0
-15.3
molybdopterin biosynthesis protein
compare
MMJJ
_RS04995
-3.0
-5.3
Tfx family DNA-binding protein
compare
MMJJ
_RS04975
-3.0
-1.9
glycosyltransferase family 4 protein
compare
MMJJ
_RS03125
-3.0
-4.8
GMC oxidoreductase
compare
MMJJ
_RS03190
-3.0
-2.0
phosphopyruvate hydratase
compare
MMJJ
_RS07155
-3.0
-10.2
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMJJ
_RS06905
-3.0
-2.7
hypothetical protein
compare
MMJJ
_RS05260
-3.0
-6.3
ATP-grasp domain-containing protein
compare
MMJJ
_RS06390
-3.0
-1.7
NADPH-dependent F420 reductase
compare
MMJJ
_RS03895
-3.0
-4.3
hydrogenase expression/formation protein HypE
compare
MMJJ
_RS07190
-3.0
-2.0
RtcB family protein
compare
MMJJ
_RS08010
-2.9
-8.0
phosphoadenosine phosphosulfate reductase family protein
compare
MMJJ
_RS06030
-2.9
-6.5
4Fe-4S binding protein
compare
MMJJ
_RS01360
-2.9
-2.0
UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
compare
MMJJ
_RS06295
-2.9
-9.9
DUF2096 family protein
compare
MMJJ
_RS05930
-2.9
-1.8
cell division protein SepF
compare
MMJJ
_RS04790
-2.9
-4.6
biotin--[acetyl-CoA-carboxylase] ligase
compare
MMJJ
_RS03055
-2.9
-3.2
hypothetical protein
compare
MMJJ
_RS08320
-2.9
-2.4
CDP-diacylglycerol--serine O-phosphatidyltransferase
compare
MMJJ
_RS03875
-2.9
-4.2
CBS domain-containing protein
compare
MMJJ
_RS03005
-2.8
-3.7
Ni-sirohydrochlorin a,c-diamide reductive cyclase catalytic subunit
compare
MMJJ
_RS06760
-2.8
-3.8
Ni-sirohydrochlorin a,c-diamide synthase
compare
MMJJ
_RS08330
-2.8
-3.7
SufD family Fe-S cluster assembly protein
compare
MMJJ
_RS05810
-2.8
-4.9
precorrin-4 C(11)-methyltransferase
compare
MMJJ
_RS03095
-2.8
-1.9
bifunctional N(6)-L-threonylcarbamoyladenine synthase/serine/threonine protein kinase
compare
MMJJ
_RS05720
-2.8
-2.6
glutamine--fructose-6-phosphate transaminase (isomerizing)
compare
MMJJ
_RS04150
-2.8
-2.9
DUF5379 domain-containing protein
compare
MMJJ
_RS06840
-2.8
-2.6
nickel-dependent hydrogenase large subunit
compare
MMJJ
_RS02090
-2.7
-4.7
tyramine--L-glutamate ligase
compare
MMJJ
_RS08405
-2.7
-13.9
nickel-dependent hydrogenase large subunit
compare
MMJJ
_RS00215
-2.7
-1.8
CCA tRNA nucleotidyltransferase
compare
MMJJ
_RS06025
-2.7
-16.6
4Fe-4S binding protein
compare
MMJJ
_RS00270
-2.7
-2.5
adenosylcobinamide-GDP ribazoletransferase
compare
MMJJ
_RS05330
-2.7
-1.8
DNA polymerase II large subunit
compare
MMJJ
_RS03660
-2.7
-3.8
DUF447 family protein
compare
MMJJ
_RS06005
-2.7
-8.3
energy conserving hydrogenase EhbF
compare
MMJJ
_RS08055
-2.6
-8.0
methanogenesis marker 14 protein
compare
MMJJ
_RS06225
-2.6
-1.7
adenosylmethionine decarboxylase
compare
MMJJ
_RS02275
-2.6
-3.8
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS00360
-2.6
-2.4
adenosylhomocysteinase
compare
MMJJ
_RS08430
-2.6
-7.0
small nuclear ribonucleoprotein
compare
MMJJ
_RS06250
-2.6
-1.7
nicotinamide-nucleotide adenylyltransferase
compare
MMJJ
_RS08340
-2.6
-5.4
archaeoflavoprotein AfpA
compare
MMJJ
_RS05950
-2.6
-3.4
bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase
compare
MMJJ
_RS04505
-2.6
-7.8
CDC48 family AAA ATPase
compare
MMJJ
_RS02040
-2.6
-2.0
Asp-tRNA(Asn) amidotransferase subunit GatC
compare
MMJJ
_RS04730
-2.6
-1.7
tyrosine decarboxylase MfnA
compare
MMJJ
_RS06200
-2.6
-2.7
phosphoglycerate dehydrogenase
compare
MMJJ
_RS00560
-2.6
-3.7
homoisocitrate dehydrogenase
compare
MMJJ
_RS07705
-2.6
-1.7
GTP-binding protein EngB
compare
MMJJ
_RS07265
-2.5
-11.8
tRNA (adenine-N1)-methyltransferase
compare
MMJJ
_RS08500
-2.5
-8.1
L-sulfolactate dehydrogenase
compare
MMJJ
_RS00550
-2.5
-7.7
AIR synthase-related protein
compare
MMJJ
_RS05620
-2.5
-2.4
CoB--CoM heterodisulfide reductase iron-sulfur subunit A family protein
compare
MMJJ
_RS09175
-2.5
-1.0
anthranilate synthase component I
compare
MMJJ
_RS06835
-2.5
-11.0
4Fe-4S binding protein
compare
MMJJ
_RS03615
-2.5
-2.8
cobalt-precorrin-8 methylmutase
compare
MMJJ
_RS01860
-2.5
-14.0
tRNA guanosine(15) transglycosylase TgtA
compare
MMJJ
_RS07470
-2.5
-2.7
50S ribosome-binding GTPase
compare
MMJJ
_RS06110
-2.5
-2.3
bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC
compare
MMJJ
_RS06215
-2.5
-5.0
agmatinase
compare
MMJJ
_RS03540
-2.5
-9.6
TIGR00289 family protein
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis JJ in rich t2 experiments