Experiment set1IT035 for Pseudomonas fluorescens FW300-N2E2

Compare to:

LB with Nickel (II) chloride hexahydrate 1 mM

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_4071 -3.7 -5.8 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_2129 -3.7 -4.8 Predicted dye-decolorizing peroxidase (DyP), YfeX-like subgroup compare
Pf6N2E2_43 -3.4 -8.7 Histidine permease YuiF compare
Pf6N2E2_5014 -3.2 -2.2 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_3574 -3.0 -12.8 Mannose-6-phosphate isomerase (EC 5.3.1.8) conserved
Pf6N2E2_2574 -2.9 -4.7 Flagellar synthesis regulator FleN compare
Pf6N2E2_5527 -2.7 -4.3 Cold shock protein CspC compare
Pf6N2E2_4352 -2.6 -4.6 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf6N2E2_5679 -2.6 -5.8 hypothetical protein compare
Pf6N2E2_3351 -2.6 -6.6 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
Pf6N2E2_3461 -2.5 -2.8 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_3908 -2.3 -9.8 Glutamate--cysteine ligase (EC 6.3.2.2) compare
Pf6N2E2_5739 -2.2 -2.5 Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family compare
Pf6N2E2_4162 -2.0 -4.2 DNA polymerase I (EC 2.7.7.7) compare
Pf6N2E2_2753 -2.0 -5.5 HtrA protease/chaperone protein compare
Pf6N2E2_4072 -1.7 -5.0 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
Pf6N2E2_2518 -1.7 -2.8 Cyclohexadienyl dehydrogenase (EC 1.3.1.12)(EC 1.3.1.43) / 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19) compare
Pf6N2E2_1625 -1.7 -4.1 Ferric reductase (1.6.99.14) compare
Pf6N2E2_4453 -1.6 -12.6 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_2218 -1.6 -5.3 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_2080 -1.5 -1.8 hypothetical protein compare
Pf6N2E2_2251 -1.5 -5.5 NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3) conserved
Pf6N2E2_2217 -1.4 -4.6 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_4987 -1.4 -1.6 MaoC-like domain protein compare
Pf6N2E2_4075 -1.4 -5.6 Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1) compare
Pf6N2E2_3835 -1.4 -3.4 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf6N2E2_3134 -1.4 -1.4 hypothetical protein compare
Pf6N2E2_4204 -1.3 -1.8 rRNA small subunit 7-methylguanosine (m7G) methyltransferase GidB compare
Pf6N2E2_4601 -1.3 -1.9 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC compare
Pf6N2E2_5430 -1.3 -7.3 Transglycosylase, Slt family compare
Pf6N2E2_4797 -1.3 -2.2 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_3261 -1.3 -3.3 hypothetical protein compare
Pf6N2E2_2252 -1.2 -4.0 NreA-like protein compare
Pf6N2E2_2646 -1.2 -1.6 FIG00953416: hypothetical protein compare
Pf6N2E2_3460 -1.2 -2.1 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_3876 -1.2 -5.2 Agmatine deiminase (EC 3.5.3.12) compare
Pf6N2E2_142 -1.2 -5.2 Exodeoxyribonuclease III (EC 3.1.11.2) compare
Pf6N2E2_5723 -1.2 -7.2 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
Pf6N2E2_3611 -1.1 -1.2 HflC protein compare
Pf6N2E2_6065 -1.1 -2.0 ABC transporter in pyoverdin gene cluster, periplasmic component compare
Pf6N2E2_4146 -1.1 -3.1 Membrane lipoprotein lipid attachment site containing protein USSDB6D compare
Pf6N2E2_4074 -1.1 -8.3 Phosphate transport system permease protein PstC (TC 3.A.1.7.1) compare
Pf6N2E2_2755 -1.1 -1.8 Sigma factor RpoE negative regulatory protein RseA compare
Pf6N2E2_2447 -1.1 -4.7 Probable protease htpX homolog (EC 3.4.24.-) compare
Pf6N2E2_2282 -1.1 -3.5 Predicted transcriptional regulator for fatty acid degradation FadQ, TetR family compare
Pf6N2E2_1632 -1.1 -4.5 Iron(III) dicitrate transport system, periplasmic iron-binding protein FecB (TC 3.A.1.14.1) compare
Pf6N2E2_4743 -1.1 -1.2 hypothetical protein compare
Pf6N2E2_3533 -1.0 -4.4 Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) compare
Pf6N2E2_4541 -1.0 -1.4 hypothetical protein compare
Pf6N2E2_1633 -1.0 -2.2 Iron(III) dicitrate transport system permease protein FecD (TC 3.A.1.14.1) compare
Pf6N2E2_3060 -1.0 -2.4 Outer membrane protein H precursor compare
Pf6N2E2_622 -1.0 -3.0 BatA (Bacteroides aerotolerance operon) compare
Pf6N2E2_2074 -1.0 -2.0 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_5671 -1.0 -3.9 Succinylglutamate desuccinylase (EC 3.5.1.96) compare
Pf6N2E2_595 -1.0 -2.2 Arsenical resistance operon repressor compare
Pf6N2E2_4369 -1.0 -2.5 Exodeoxyribonuclease III (EC 3.1.11.2) compare
Pf6N2E2_5219 -1.0 -6.4 FIG140336: TPR domain protein compare
Pf6N2E2_5841 -1.0 -1.3 GlcG protein compare
Pf6N2E2_621 -1.0 -4.9 TPR domain protein in aerotolerance operon compare
Pf6N2E2_2068 -1.0 -5.4 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) compare
Pf6N2E2_1299 -0.9 -1.6 Transcriptional regulator, TetR family compare
Pf6N2E2_1821 -0.9 -1.8 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system compare
Pf6N2E2_1636 -0.9 -5.3 Ferrichrome-iron receptor compare
Pf6N2E2_4640 -0.9 -1.7 hypothetical protein compare
Pf6N2E2_2065 -0.9 -2.6 Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) compare
Pf6N2E2_2519 -0.9 -1.1 Biosynthetic Aromatic amino acid aminotransferase beta (EC 2.6.1.57) compare
Pf6N2E2_5711 -0.9 -5.1 tRNA(Cytosine32)-2-thiocytidine synthetase compare
Pf6N2E2_3270 -0.9 -2.7 Hypothetical ATP-binding protein UPF0042, contains P-loop compare
Pf6N2E2_1043 -0.9 -3.7 Transcriptional regulator, IclR family compare
Pf6N2E2_3969 -0.9 -1.0 Membrane-fusion protein compare
Pf6N2E2_238 -0.9 -1.5 hypothetical protein compare
Pf6N2E2_5520 -0.9 -4.1 Sensory box histidine kinase compare
Pf6N2E2_5536 -0.9 -1.5 Holliday junction DNA helicase RuvA compare
Pf6N2E2_5761 -0.9 -1.5 Transcriptional regulator, TetR family compare
Pf6N2E2_1667 -0.9 -2.7 Fumarylacetoacetate hydrolase family protein compare
Pf6N2E2_288 -0.9 -2.1 Isocitrate dehydrogenase [NADP] (EC 1.1.1.42); Monomeric isocitrate dehydrogenase [NADP] (EC 1.1.1.42) compare
Pf6N2E2_3624 -0.9 -3.7 Flagellar motor rotation protein MotB compare
Pf6N2E2_2064 -0.9 -3.0 Cobalt-precorrin-3b C17-methyltransferase compare
Pf6N2E2_4612 -0.9 -3.8 Glutathione synthetase (EC 6.3.2.3) compare
Pf6N2E2_3656 -0.9 -4.1 Probable transcription regulator Mig-14 compare
Pf6N2E2_2219 -0.9 -1.4 Cell division trigger factor (EC 5.2.1.8) compare
Pf6N2E2_5242 -0.9 -1.1 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_4351 -0.8 -5.1 Predicted signal transduction protein compare
Pf6N2E2_2317 -0.8 -2.3 Putative analog of CcoH, COG3198 compare
Pf6N2E2_4353 -0.8 -2.9 Hydrogen peroxide-inducible genes activator compare
Pf6N2E2_6047 -0.8 -1.5 hypothetical protein compare
Pf6N2E2_2285 -0.8 -1.4 FIG00954079: hypothetical protein compare
Pf6N2E2_2264 -0.8 -3.1 NADPH dependent preQ0 reductase (EC 1.7.1.13) compare
Pf6N2E2_3338 -0.8 -1.3 1-phosphofructokinase (EC 2.7.1.56) compare
Pf6N2E2_302 -0.8 -3.0 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_4974 -0.8 -4.0 DedA protein compare
Pf6N2E2_1162 -0.8 -1.5 Transmembrane amino acid efflux protein compare
Pf6N2E2_5986 -0.8 -2.3 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_2477 -0.8 -1.9 ABC transporter ATP-binding protein YvcR compare
Pf6N2E2_5316 -0.8 -1.3 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_1635 -0.8 -3.2 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components compare
Pf6N2E2_3947 -0.8 -1.9 Cd(II)/Pb(II)-responsive transcriptional regulator compare
Pf6N2E2_723 -0.8 -1.7 FIG138517: Putative lipid carrier protein compare
Pf6N2E2_4447 -0.8 -6.7 Cytochrome c family protein conserved
Pf6N2E2_5017 -0.8 -4.2 Phosphate starvation-inducible protein PhoH, predicted ATPase compare
Pf6N2E2_2156 -0.8 -2.1 Putative polyketide synthase (Fragment) compare
Pf6N2E2_451 -0.7 -2.0 transcriptional regulator MvaT, P16 subunit, putative compare
Pf6N2E2_1741 -0.7 -3.2 Transketolase, N-terminal section (EC 2.2.1.1) compare
Pf6N2E2_3841 -0.7 -3.7 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_4464 -0.7 -1.9 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases / CDP-6-deoxy-delta-3,4-glucoseen reductase-like compare
Pf6N2E2_3252 -0.7 -3.6 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_6140 -0.7 -0.9 Large Subunit Ribosomal RNA; lsuRNA; LSU rRNA compare
Pf6N2E2_3782 -0.7 -2.4 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_4451 -0.7 -3.8 FIG139438: lipoprotein B compare
Pf6N2E2_1085 -0.7 -1.7 Fe2+/Zn2+ uptake regulation proteins compare
Pf6N2E2_384 -0.7 -2.0 Glycine cleavage system transcriptional activator compare
Pf6N2E2_3251 -0.7 -4.8 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_4638 -0.7 -1.5 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_4391 -0.7 -3.8 D-amino acid dehydrogenase small subunit (EC 1.4.99.1) compare
Pf6N2E2_1082 -0.7 -1.2 CopG protein compare
Pf6N2E2_309 -0.7 -1.1 FIG00957702: hypothetical protein compare
Pf6N2E2_1802 -0.7 -3.7 polysaccharide deacetylase compare
Pf6N2E2_156 -0.7 -1.0 Carbon storage regulator compare
Pf6N2E2_2012 -0.7 -1.4 hypothetical protein compare
Pf6N2E2_5742 -0.7 -3.3 Cobyric acid synthase (EC 6.3.5.10) compare
Pf6N2E2_5078 -0.7 -2.2 Carbon starvation protein A compare
Pf6N2E2_563 -0.7 -3.7 Serine transporter compare
Pf6N2E2_88 -0.7 -1.4 hypothetical protein compare
Pf6N2E2_4416 -0.7 -1.8 Tyrosine recombinase XerC compare
Pf6N2E2_3786 -0.7 -2.1 Twin-arginine translocation protein TatC compare
Pf6N2E2_4273 -0.7 -4.3 ATP-dependent DNA helicase UvrD/PcrA compare
Pf6N2E2_5262 -0.7 -2.1 FKBP-type peptidyl-prolyl cis-trans isomerase SlyD (EC 5.2.1.8) compare
Pf6N2E2_4618 -0.7 -2.5 Chemotaxis signal transduction protein compare
Pf6N2E2_3505 -0.7 -1.0 Translation initiation factor SUI1-related protein compare
Pf6N2E2_5616 -0.7 -2.6 outer membrane component of uptake system, probably for ferrous iron (from data) compare
Pf6N2E2_3666 -0.7 -2.4 InaA protein compare
Pf6N2E2_3326 -0.7 -1.2 hypothetical protein compare
Pf6N2E2_3219 -0.7 -2.8 hypothetical protein compare
Pf6N2E2_5111 -0.7 -2.3 FKBP-type peptidyl-prolyl cis-trans isomerase SlpA (EC 5.2.1.8) compare
Pf6N2E2_5340 -0.7 -2.0 Stringent starvation protein A compare
Pf6N2E2_3537 -0.7 -2.4 Cobalt-precorrin-6x reductase (EC 1.3.1.54) compare
Pf6N2E2_2438 -0.7 -1.3 hypothetical protein compare
Pf6N2E2_3062 -0.6 -2.7 Membrane-associated zinc metalloprotease compare
Pf6N2E2_5337 -0.6 -2.7 Ubiquinol-cytochrome C reductase iron-sulfur subunit (EC 1.10.2.2) compare
Pf6N2E2_3229 -0.6 -2.3 Putative glutathione transporter, ATP-binding component compare
Pf6N2E2_2527 -0.6 -3.0 Oxidoreductase, short chain dehydrogenase/reductase family compare
Pf6N2E2_2062 -0.6 -1.7 FIG00955561: hypothetical protein compare
Pf6N2E2_4654 -0.6 -3.2 hypothetical protein compare
Pf6N2E2_5794 -0.6 -1.2 Ribosomal large subunit pseudouridine synthase A (EC 4.2.1.70) compare
Pf6N2E2_1884 -0.6 -3.2 oxidoreductase, short-chain dehydrogenase/reductase family compare
Pf6N2E2_2073 -0.6 -3.9 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_5049 -0.6 -1.3 acetyltransferase, GNAT family compare
Pf6N2E2_799 -0.6 -2.2 hypothetical protein compare
Pf6N2E2_3100 -0.6 -2.4 FIG00953063: hypothetical protein compare
Pf6N2E2_4417 -0.6 -1.8 Protein of unknown function DUF484 compare
Pf6N2E2_5738 -0.6 -3.7 Cobyrinic acid A,C-diamide synthase compare
Pf6N2E2_5001 -0.6 -1.2 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) compare
Pf6N2E2_3842 -0.6 -1.8 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_3607 -0.6 -3.5 3'-to-5' exoribonuclease RNase R compare
Pf6N2E2_1128 -0.6 -1.2 Two-component response regulator compare
Pf6N2E2_4795 -0.6 -1.5 Acyl-phosphate:glycerol-3-phosphate O-acyltransferase PlsY compare
Pf6N2E2_5086 -0.6 -0.9 hypothetical protein compare
Pf6N2E2_4422 -0.6 -1.2 Frataxin homolog CyaY, facilitates iron supply for heme A synthesis or Fe-S cluster assembly compare
Pf6N2E2_1545 -0.6 -2.2 N-carbamoylputrescine amidase (EC 3.5.1.53) compare
Pf6N2E2_1975 -0.6 -1.4 Integrase regulator R compare
Pf6N2E2_99 -0.6 -2.4 hypothetical protein compare
Pf6N2E2_4399 -0.6 -2.1 GGDEF domain/EAL domain protein compare
Pf6N2E2_5743 -0.6 -2.6 Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) compare
Pf6N2E2_2253 -0.6 -1.5 hypothetical protein compare
Pf6N2E2_4653 -0.6 -3.4 Transcriptional regulator, ArsR family / Methyltransferase fusion compare
Pf6N2E2_2277 -0.6 -1.0 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_4206 -0.6 -0.9 Chromosome (plasmid) partitioning protein ParB compare
Pf6N2E2_3655 -0.6 -4.2 Hypothetical protein FIG015671 in large core OS assembly cluster compare
Pf6N2E2_2756 -0.6 -3.5 RNA polymerase sigma-H factor AlgT compare
Pf6N2E2_5579 -0.6 -3.5 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_1634 -0.6 -1.8 ABC-type Fe3+-siderophore transport system, permease component compare
Pf6N2E2_3258 -0.6 -2.2 Uncharacterized ABC transporter, periplasmic component YrbD compare
Pf6N2E2_5756 -0.6 -1.5 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_3940 -0.5 -3.5 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_2060 -0.5 -3.9 CobN component of cobalt chelatase involved in B12 biosynthesis compare
Pf6N2E2_1972 -0.5 -1.5 FIG004780: hypothetical protein in PFGI-1-like cluster compare
Pf6N2E2_4197 -0.5 -3.6 DNA recombination and repair protein RecF compare
Pf6N2E2_756 -0.5 -1.7 hypothetical protein compare
Pf6N2E2_4886 -0.5 -3.9 Catalase (EC 1.11.1.6) compare
Pf6N2E2_3534 -0.5 -1.5 Cobalamin biosynthesis protein CobG compare
Pf6N2E2_5411 -0.5 -1.9 FIG00955494: hypothetical protein compare
Pf6N2E2_218 -0.5 -2.4 hypothetical protein compare
Pf6N2E2_3763 -0.5 -1.0 hypothetical protein compare
Pf6N2E2_3014 -0.5 -1.4 P2-like prophage tail protein X compare
Pf6N2E2_291 -0.5 -2.3 ATP-dependent Clp protease adaptor protein ClpS compare
Pf6N2E2_4276 -0.5 -2.8 Phosphogluconate repressor HexR, RpiR family compare
Pf6N2E2_3625 -0.5 -3.7 Flagellar motor rotation protein MotA compare
Pf6N2E2_3839 -0.5 -2.0 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_295 -0.5 -1.5 Leucyl/phenylalanyl-tRNA--protein transferase (EC 2.3.2.6) compare
Pf6N2E2_2792 -0.5 -1.2 Antitoxin 1 compare
Pf6N2E2_5902 -0.5 -1.5 hypothetical protein compare
Pf6N2E2_2274 -0.5 -2.4 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) compare
Pf6N2E2_4678 -0.5 -0.7 hypothetical protein compare
Pf6N2E2_5944 -0.5 -2.6 Ribosomal large subunit pseudouridine synthase C (EC 4.2.1.70) compare
Pf6N2E2_2250 -0.5 -3.2 Transcriptional regulator compare
Pf6N2E2_1176 -0.5 -2.1 Mll2356 protein compare
Pf6N2E2_5428 -0.5 -2.4 DNA recombination and repair protein RecO compare
Pf6N2E2_3486 -0.5 -2.9 FIG00953575: hypothetical protein compare
Pf6N2E2_4159 -0.5 -1.9 Cytochrome c4 compare
Pf6N2E2_3077 -0.5 -1.4 FIG138056: a glutathione-dependent thiol reductase compare


Specific Phenotypes

For 2 genes in this experiment

For stress Nickel (II) chloride hexahydrate in Pseudomonas fluorescens FW300-N2E2

For stress Nickel (II) chloride hexahydrate across organisms