Experiment set1IT035 for Pseudomonas fluorescens FW300-N1B4

Compare to:

Sodium pyruvate carbon source

200 most important genes:

  gene name fitness t score description  
Pf1N1B4_1565 -2.9 -4.8 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf1N1B4_2880 -2.9 -13.0 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf1N1B4_2272 -2.8 -4.6 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf1N1B4_1831 -2.8 -12.3 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf1N1B4_1624 -2.6 -9.4 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf1N1B4_847 -2.6 -9.4 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf1N1B4_6 -2.5 -5.8 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf1N1B4_15 -2.5 -5.3 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf1N1B4_2549 -2.5 -9.5 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf1N1B4_2303 -2.4 -13.4 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf1N1B4_12 -2.4 -7.7 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf1N1B4_2545 -2.3 -13.7 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
Pf1N1B4_1534 -2.3 -16.2 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf1N1B4_2858 -2.3 -11.1 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf1N1B4_1533 -2.3 -8.5 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf1N1B4_2009 -2.2 -5.7 LysR family transcriptional regulator PA5437 compare
Pf1N1B4_1434 -2.2 -6.8 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf1N1B4_742 -2.2 -8.8 Argininosuccinate synthase (EC 6.3.4.5) compare
Pf1N1B4_2879 -2.1 -7.4 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf1N1B4_1830 -2.1 -8.2 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf1N1B4_2338 -2.1 -8.5 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf1N1B4_4065 -2.1 -7.9 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf1N1B4_5665 -2.0 -5.6 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf1N1B4_2548 -2.0 -6.7 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf1N1B4_1535 -2.0 -3.9 hypothetical protein compare
Pf1N1B4_1906 -1.9 -3.8 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) compare
Pf1N1B4_1315 -1.9 -8.0 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) compare
Pf1N1B4_2337 -1.9 -5.5 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf1N1B4_350 -1.9 -6.5 Chorismate mutase I (EC 5.4.99.5) / Prephenate dehydratase (EC 4.2.1.51) compare
Pf1N1B4_1617 -1.9 -7.1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (EC 5.4.2.1) compare
Pf1N1B4_1627 -1.9 -4.6 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf1N1B4_2878 -1.8 -8.0 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf1N1B4_1626 -1.8 -6.9 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf1N1B4_762 -1.8 -6.1 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf1N1B4_3725 -1.8 -5.7 Sensory box histidine kinase/response regulator compare
Pf1N1B4_1307 -1.8 -2.6 3-dehydroquinate dehydratase II (EC 4.2.1.10) compare
Pf1N1B4_3917 -1.7 -4.4 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf1N1B4_327 -1.7 -2.5 hypothetical protein compare
Pf1N1B4_2547 -1.7 -3.1 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
Pf1N1B4_3812 -1.7 -7.3 Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) compare
Pf1N1B4_3506 -1.7 -6.9 Cysteine synthase B (EC 2.5.1.47) compare
Pf1N1B4_2859 -1.7 -11.3 Two-component sensor CbrA: intrcellular carbon:nitrogen balance compare
Pf1N1B4_1328 -1.7 -2.2 Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) compare
Pf1N1B4_2282 -1.6 -7.9 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf1N1B4_2010 -1.6 -5.5 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf1N1B4_4028 -1.6 -3.8 NADH-ubiquinone oxidoreductase chain N (EC 1.6.5.3) compare
Pf1N1B4_1067 -1.6 -4.1 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf1N1B4_2384 -1.6 -8.0 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf1N1B4_3672 -1.5 -4.7 small component of pyruvate transporter (yjcH-like) (from data) compare
Pf1N1B4_2011 -1.5 -7.0 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf1N1B4_4835 -1.5 -2.1 Carbon starvation protein A compare
Pf1N1B4_899 -1.4 -2.1 DNA polymerase III chi subunit (EC 2.7.7.7) compare
Pf1N1B4_3518 -1.4 -2.9 Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) compare
Pf1N1B4_2823 -1.4 -2.3 COG1496: Uncharacterized conserved protein compare
Pf1N1B4_4833 -1.4 -3.7 DNA-binding response regulator, LuxR family compare
Pf1N1B4_2280 -1.4 -7.0 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf1N1B4_1408 -1.4 -3.0 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf1N1B4_3985 -1.3 -2.5 Methylglutaconyl-CoA hydratase (EC 4.2.1.18) compare
Pf1N1B4_5330 -1.3 -1.9 hypothetical protein compare
Pf1N1B4_1625 -1.3 -3.3 FIG00956267: hypothetical protein compare
Pf1N1B4_1234 -1.3 -3.6 Exodeoxyribonuclease V alpha chain (EC 3.1.11.5) compare
Pf1N1B4_4343 -1.3 -3.1 hypothetical protein compare
Pf1N1B4_4729 -1.3 -2.3 Hemolysin-type calcium-binding region compare
Pf1N1B4_3726 -1.3 -4.5 Sensory box histidine kinase/response regulator compare
Pf1N1B4_3697 -1.3 -5.9 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf1N1B4_1472 -1.3 -1.5 Lipopolysaccharide heptosyltransferase I (EC 2.4.1.-) compare
Pf1N1B4_1 -1.3 -1.7 Colicin V production protein compare
Pf1N1B4_4030 -1.3 -3.1 NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3) compare
Pf1N1B4_1317 -1.2 -2.6 Sensor histidine kinase/response regulator compare
Pf1N1B4_2491 -1.2 -3.1 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf1N1B4_2486 -1.2 -2.2 hypothetical protein compare
Pf1N1B4_5720 -1.2 -2.1 hypothetical protein compare
Pf1N1B4_3935 -1.1 -2.9 Major facilitator family transporter compare
Pf1N1B4_101 -1.1 -2.1 hypothetical protein compare
Pf1N1B4_2400 -1.1 -2.3 FIG00955006: hypothetical protein compare
Pf1N1B4_275 -1.1 -1.8 Organic hydroperoxide resistance transcriptional regulator compare
Pf1N1B4_4953 -1.1 -2.6 Selenocysteine-specific translation elongation factor compare
Pf1N1B4_3673 -1.1 -6.8 large component of pyruvate transporter (actP-like) (from data) conserved
Pf1N1B4_2935 -1.1 -2.2 Hypoxanthine-guanine phosphoribosyltransferase (EC 2.4.2.8) compare
Pf1N1B4_5666 -1.1 -2.3 Oxidoreductase probably involved in sulfite reduction compare
Pf1N1B4_2021 -1.1 -1.6 hypothetical protein compare
Pf1N1B4_2870 -1.1 -1.6 Regulator of competence-specific genes compare
Pf1N1B4_4029 -1.1 -2.6 NADH-ubiquinone oxidoreductase chain M (EC 1.6.5.3) compare
Pf1N1B4_3081 -1.0 -9.1 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
Pf1N1B4_2178 -1.0 -1.4 Regulator of nucleoside diphosphate kinase compare
Pf1N1B4_1611 -1.0 -3.7 Nitrogen regulation protein NR(I) compare
Pf1N1B4_4857 -1.0 -4.3 Chemotaxis protein methyltransferase CheR (EC 2.1.1.80) compare
Pf1N1B4_3325 -1.0 -1.9 Sigma factor RpoE negative regulatory protein RseB precursor compare
Pf1N1B4_578 -1.0 -1.9 enoyl-CoA hydratase, R-specific compare
Pf1N1B4_5437 -1.0 -3.2 hypothetical protein compare
Pf1N1B4_2706 -1.0 -2.3 FIG00954871: hypothetical protein compare
Pf1N1B4_932 -1.0 -1.5 FIG00963370: hypothetical protein compare
Pf1N1B4_2736 -1.0 -1.7 ATP-dependent RNA helicase PA3950 compare
Pf1N1B4_1247 -1.0 -2.2 transcriptional regulator, MerR family compare
Pf1N1B4_108 -1.0 -2.3 FIG00954456: hypothetical protein compare
Pf1N1B4_2112 -0.9 -6.8 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
Pf1N1B4_1566 -0.9 -4.1 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf1N1B4_4040 -0.9 -2.1 NADH-ubiquinone oxidoreductase chain B (EC 1.6.5.3) compare
Pf1N1B4_32 -0.9 -2.6 Transcriptional regulator, TetR family compare
Pf1N1B4_4004 -0.9 -2.2 Peptidyl-prolyl cis-trans isomerase PpiB (EC 5.2.1.8) compare
Pf1N1B4_3038 -0.9 -4.3 Chemotaxis response regulator protein-glutamate methylesterase CheB (EC 3.1.1.61) compare
Pf1N1B4_5439 -0.9 -1.8 hypothetical protein compare
Pf1N1B4_27 -0.9 -2.4 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf1N1B4_3990 -0.9 -3.1 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
Pf1N1B4_5443 -0.9 -3.1 hypothetical protein compare
Pf1N1B4_5425 -0.9 -1.4 DNA-binding protein HU-beta compare
Pf1N1B4_2037 -0.9 -2.2 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
Pf1N1B4_1837 -0.9 -1.3 Osmotically inducible protein C compare
Pf1N1B4_3413 -0.9 -1.3 Transcriptional regulator, LysR family compare
Pf1N1B4_5018 -0.9 -1.9 FIG00962345: hypothetical protein compare
Pf1N1B4_886 -0.8 -1.6 FIG137478: Hypothetical protein compare
Pf1N1B4_6041 -0.8 -1.6 Carbon storage regulator compare
Pf1N1B4_1590 -0.8 -3.5 Histidine utilization repressor compare
Pf1N1B4_4612 -0.8 -1.7 FIG00954117: hypothetical protein compare
Pf1N1B4_4446 -0.8 -1.8 DNA topoisomerase III (EC 5.99.1.2) compare
Pf1N1B4_3200 -0.8 -2.2 Outer membrane lipoprotein compare
Pf1N1B4_2860 -0.8 -3.8 FIG00954153: hypothetical protein compare
Pf1N1B4_4139 -0.8 -1.7 Transcriptional regulator, MerR family compare
Pf1N1B4_4108 -0.8 -1.6 Hydrolase, alpha/beta fold family compare
Pf1N1B4_3214 -0.8 -2.5 Branched-chain amino acid transport ATP-binding protein LivF (TC 3.A.1.4.1) compare
Pf1N1B4_672 -0.8 -2.1 FIG00955538: hypothetical protein compare
Pf1N1B4_2734 -0.8 -1.2 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system compare
Pf1N1B4_2210 -0.8 -1.6 Glutamate transport ATP-binding protein compare
Pf1N1B4_4745 -0.8 -1.7 Transcriptional regulator, LysR family compare
Pf1N1B4_1568 -0.8 -2.0 Twin-arginine translocation protein TatB compare
Pf1N1B4_4532 -0.8 -2.0 ClpB protein compare
Pf1N1B4_867 -0.8 -2.4 Serine acetyltransferase (EC 2.3.1.30) compare
Pf1N1B4_5452 -0.8 -2.7 hypothetical protein compare
Pf1N1B4_13 -0.8 -1.9 SAM-dependent methyltransferase YafE (UbiE paralog) compare
Pf1N1B4_929 -0.8 -2.0 FIG00964214: hypothetical protein compare
Pf1N1B4_669 -0.8 -2.3 INTEGRAL MEMBRANE PROTEIN (Rhomboid family) compare
Pf1N1B4_4486 -0.8 -1.9 Outer membrane protein (porin) compare
Pf1N1B4_3799 -0.8 -1.7 1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51) compare
Pf1N1B4_5645 -0.8 -1.9 Glutamine ABC transporter, periplasmic glutamine-binding protein (TC 3.A.1.3.2) compare
Pf1N1B4_2169 -0.8 -1.9 FIG00953808: hypothetical protein compare
Pf1N1B4_1975 -0.8 -1.7 Transcriptional regulator, AsnC family compare
Pf1N1B4_257 -0.8 -3.3 sensor histidine kinase/response regulator compare
Pf1N1B4_4393 -0.8 -1.6 Ferredoxin reductase compare
Pf1N1B4_617 -0.8 -1.3 Carbamate kinase (EC 2.7.2.2) compare
Pf1N1B4_3541 -0.8 -2.0 FIG027190: Putative transmembrane protein compare
Pf1N1B4_3494 -0.8 -2.0 Flavoprotein WrbA compare
Pf1N1B4_224 -0.8 -1.6 Isohexenylglutaconyl-CoA hydratase compare
Pf1N1B4_3918 -0.7 -2.1 Thiamin biosynthesis lipoprotein ApbE compare
Pf1N1B4_1358 -0.7 -2.2 DnaJ-class molecular chaperone CbpA compare
Pf1N1B4_2768 -0.7 -1.8 DNA repair protein RadA compare
Pf1N1B4_6004 -0.7 -2.6 tgtA5 cluster protein 1 compare
Pf1N1B4_5305 -0.7 -2.9 hypothetical protein compare
Pf1N1B4_4960 -0.7 -1.6 Protein containing transglutaminase-like domain, putative cysteine protease compare
Pf1N1B4_348 -0.7 -2.5 Cyclohexadienyl dehydrogenase (EC 1.3.1.12)(EC 1.3.1.43) / 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19) compare
Pf1N1B4_2005 -0.7 -1.0 ATP-dependent DNA helicase UvrD/PcrA compare
Pf1N1B4_2105 -0.7 -1.3 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf1N1B4_5619 -0.7 -3.1 BarA-associated response regulator UvrY (= GacA = SirA) compare
Pf1N1B4_1811 -0.7 -3.0 RNA polymerase sigma-70 factor, ECF subfamily compare
Pf1N1B4_6037 -0.7 -1.9 L-asparaginase (EC 3.5.1.1) compare
Pf1N1B4_5663 -0.7 -1.5 Periplasmic sugar-binding domain protein compare
Pf1N1B4_4385 -0.7 -1.6 Gfa-like protein compare
Pf1N1B4_4603 -0.7 -1.6 hypothetical protein compare
Pf1N1B4_2682 -0.7 -1.2 Antiholin-like protein LrgA compare
Pf1N1B4_2969 -0.7 -5.0 ATPase, AFG1 family compare
Pf1N1B4_2856 -0.7 -2.3 Poly(A) polymerase (EC 2.7.7.19) compare
Pf1N1B4_4563 -0.7 -1.5 Sulfate transporter compare
Pf1N1B4_241 -0.7 -1.6 Thiol-disulfide isomerase and thioredoxins compare
Pf1N1B4_3833 -0.7 -3.5 Major porin and structural outer membrane porin OprF compare
Pf1N1B4_3169 -0.7 -2.4 methylated-DNA--protein-cysteine methyltransferase-related protein compare
Pf1N1B4_1610 -0.7 -2.4 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
Pf1N1B4_198 -0.7 -1.6 FIG137877: Hypothetical protein in pyoverdin gene cluster compare
Pf1N1B4_977 -0.7 -2.1 Molybdenum cofactor biosynthesis protein MoaC compare
Pf1N1B4_4462 -0.7 -1.2 LysR family transcriptional regulator YbhD compare
Pf1N1B4_4103 -0.7 -1.0 Flagellar synthesis regulator FleN compare
Pf1N1B4_2218 -0.7 -3.4 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases / CDP-6-deoxy-delta-3,4-glucoseen reductase-like compare
Pf1N1B4_1870 -0.7 -1.6 Zinc ABC transporter, ATP-binding protein ZnuC compare
Pf1N1B4_3527 -0.7 -2.5 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit compare
Pf1N1B4_5549 -0.7 -1.4 hypothetical protein compare
Pf1N1B4_3439 -0.7 -1.9 hypothetical protein compare
Pf1N1B4_5631 -0.7 -1.6 Sigma-54 dependent transcriptional regulator compare
Pf1N1B4_133 -0.7 -2.0 Sigma-70 factor FpvI (ECF subfamily), controling pyoverdin biosynthesis compare
Pf1N1B4_2485 -0.7 -1.3 Competence protein F homolog, phosphoribosyltransferase domain; protein YhgH required for utilization of DNA as sole source of carbon and energy compare
Pf1N1B4_429 -0.7 -1.8 FIG00964214: hypothetical protein compare
Pf1N1B4_2464 -0.7 -1.5 Ribosomal protein S6 glutaminyl transferase compare
Pf1N1B4_4836 -0.6 -1.8 COG2879, Hypothetical small protein yjiX compare
Pf1N1B4_2377 -0.6 -3.1 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf1N1B4_4039 -0.6 -3.0 NADH-ubiquinone oxidoreductase chain C (EC 1.6.5.3) / NADH-ubiquinone oxidoreductase chain D (EC 1.6.5.3) compare
Pf1N1B4_2541 -0.6 -3.3 Spermidine Putrescine ABC transporter permease component potC (TC_3.A.1.11.1) compare
Pf1N1B4_693 -0.6 -2.2 ABC spermidine/putrescine transporter, inner membrane subunit compare
Pf1N1B4_4301 -0.6 -2.0 hypothetical protein compare
Pf1N1B4_4974 -0.6 -1.8 Protease subunit of ATP-dependent Clp proteases compare
Pf1N1B4_3785 -0.6 -1.3 FOG: Ankyrin repeat compare
Pf1N1B4_1332 -0.6 -1.5 Cobalt-precorrin-6 synthase, anaerobic compare
Pf1N1B4_3911 -0.6 -2.1 Predicted transcriptional regulator for fatty acid degradation FadQ, TetR family compare
Pf1N1B4_4473 -0.6 -1.1 Homoserine/homoserine lactone efflux protein compare
Pf1N1B4_4200 -0.6 -2.3 PhaK-like protein compare
Pf1N1B4_4041 -0.6 -1.8 NADH ubiquinone oxidoreductase chain A (EC 1.6.5.3) compare
Pf1N1B4_5015 -0.6 -2.1 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) compare
Pf1N1B4_110 -0.6 -2.4 Queuosine biosynthesis QueD, PTPS-I compare
Pf1N1B4_5299 -0.6 -1.8 hypothetical protein compare
Pf1N1B4_6036 -0.6 -1.2 FIG00953132: hypothetical protein compare
Pf1N1B4_5813 -0.6 -1.3 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) compare
Pf1N1B4_1096 -0.6 -2.2 Septum formation protein Maf compare
Pf1N1B4_2769 -0.6 -1.9 FIG00954896: hypothetical protein compare
Pf1N1B4_1239 -0.6 -3.4 Omega-amino acid--pyruvate aminotransferase (EC 2.6.1.18) compare


Specific Phenotypes

For 2 genes in this experiment

For carbon source Sodium pyruvate in Pseudomonas fluorescens FW300-N1B4

For carbon source Sodium pyruvate across organisms