Experiment set1IT035 for Pseudomonas fluorescens FW300-N1B4

Compare to:

Sodium pyruvate carbon source

200 most detrimental genes:

  gene name fitness t score description  
Pf1N1B4_695 +2.0 3.4 Aldehyde dehydrogenase (EC 1.2.1.3) compare
Pf1N1B4_507 +1.5 3.1 FIG00956448: hypothetical protein compare
Pf1N1B4_5331 +1.4 3.9 hypothetical protein compare
Pf1N1B4_2060 +1.3 3.7 hypothetical protein compare
Pf1N1B4_188 +1.2 2.5 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf1N1B4_4509 +1.2 2.5 Aldose 1-epimerase compare
Pf1N1B4_5242 +1.2 2.5 hypothetical protein compare
Pf1N1B4_2269 +1.2 3.0 Purine nucleoside phosphorylase (EC 2.4.2.1) compare
Pf1N1B4_2642 +1.1 3.4 Methionine ABC transporter ATP-binding protein compare
Pf1N1B4_267 +1.0 2.7 Enoyl-CoA hydratase (EC 4.2.1.17) compare
Pf1N1B4_3582 +1.0 1.5 C-methyltransferase compare
Pf1N1B4_4107 +1.0 2.2 Probable glutathione S-transferase (EC 2.5.1.18), YfcF homolog compare
Pf1N1B4_4404 +0.9 3.2 Transcriptional regulator, LysR family compare
Pf1N1B4_5560 +0.9 1.9 hypothetical protein compare
Pf1N1B4_2851 +0.9 1.3 hypothetical protein compare
Pf1N1B4_3485 +0.9 2.2 hypothetical protein compare
Pf1N1B4_1105 +0.8 2.0 4-carboxymuconolactone decarboxylase (EC 4.1.1.44) compare
Pf1N1B4_4587 +0.8 1.4 probable dioxygenase compare
Pf1N1B4_3408 +0.8 1.6 Transcriptional regulator, AraC family compare
Pf1N1B4_1511 +0.8 1.6 FIG027190: Putative transmembrane protein compare
Pf1N1B4_218 +0.8 4.9 Periplasmic binding protein compare
Pf1N1B4_5886 +0.8 3.0 Undecaprenyl-phosphate galactosephosphotransferase (EC 2.7.8.6) compare
Pf1N1B4_1679 +0.8 1.5 Membrane-fusion protein compare
Pf1N1B4_4422 +0.8 1.7 ABC transporter amino acid-binding protein compare
Pf1N1B4_4445 +0.8 3.1 acetyltransferase, GNAT family compare
Pf1N1B4_4481 +0.8 2.0 Transcriptional regulator BkdR of isoleucine and valine catabolism operon compare
Pf1N1B4_5224 +0.7 2.3 tRNA-Arg-CCT compare
Pf1N1B4_5243 +0.7 2.6 hypothetical protein compare
Pf1N1B4_3547 +0.7 1.5 DNA-binding response regulator compare
Pf1N1B4_619 +0.7 1.2 Sigma-54 dependent transcriptional regulator/sensory box protein compare
Pf1N1B4_1243 +0.7 2.8 ABC transporter ATP-binding protein compare
Pf1N1B4_5357 +0.7 1.3 hypothetical protein compare
Pf1N1B4_3982 +0.7 3.2 FIG00953347: hypothetical protein compare
Pf1N1B4_260 +0.7 2.3 Peptide methionine sulfoxide reductase MsrB (EC 1.8.4.12) compare
Pf1N1B4_3794 +0.7 2.3 hypothetical protein compare
Pf1N1B4_3991 +0.7 0.9 Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family compare
Pf1N1B4_3141 +0.7 1.0 FIG00959768: hypothetical protein compare
Pf1N1B4_5408 +0.7 2.5 hypothetical protein compare
Pf1N1B4_3936 +0.7 1.9 Transcriptional regulator, LysR family compare
Pf1N1B4_5877 +0.7 2.3 FIG00967533: hypothetical protein compare
Pf1N1B4_3814 +0.7 2.8 Para-aminobenzoate synthase, aminase component (EC 2.6.1.85) compare
Pf1N1B4_5296 +0.7 2.5 hypothetical protein compare
Pf1N1B4_5365 +0.7 1.7 hypothetical protein compare
Pf1N1B4_1185 +0.7 3.5 Lactate-responsive regulator LldR in Enterobacteria, GntR family compare
Pf1N1B4_3775 +0.7 1.7 FIG00956876: hypothetical protein compare
Pf1N1B4_606 +0.7 1.7 Iron siderophore sensor protein compare
Pf1N1B4_2359 +0.7 2.0 Chemotaxis signal transduction protein compare
Pf1N1B4_4531 +0.7 1.2 FIG01221261: hypothetical protein compare
Pf1N1B4_4533 +0.7 1.2 Uncharacterized protein ImpH/VasB compare
Pf1N1B4_5371 +0.7 1.6 hypothetical protein compare
Pf1N1B4_4281 +0.6 3.1 Glyceraldehyde-3-phosphate ketol-isomerase (EC 5.3.1.1) compare
Pf1N1B4_919 +0.6 1.9 hypothetical protein compare
Pf1N1B4_4438 +0.6 1.6 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) compare
Pf1N1B4_4744 +0.6 2.0 Transcriptional regulator, LysR family compare
Pf1N1B4_5411 +0.6 2.3 hypothetical protein compare
Pf1N1B4_5292 +0.6 1.2 hypothetical protein compare
Pf1N1B4_4204 +0.6 2.4 FldA protein compare
Pf1N1B4_855 +0.6 1.6 FIG021952: putative membrane protein compare
Pf1N1B4_2476 +0.6 3.9 Predicted signal-transduction protein containing cAMP-binding and CBS domains compare
Pf1N1B4_5979 +0.6 2.0 Ureidoglycolate/malate/sulfolactate dehydrogenase family (EC 1.1.1.-) compare
Pf1N1B4_2048 +0.6 1.5 hypothetical protein compare
Pf1N1B4_409 +0.6 2.8 ABC transporter for D-galactose/L-arabinose, permease component (from data) compare
Pf1N1B4_516 +0.6 1.9 Sensor histidine kinase compare
Pf1N1B4_5650 +0.6 2.1 Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipi n synthases and related enzymes compare
Pf1N1B4_399 +0.6 1.5 2-dehydro-3-deoxyphosphogalactonate aldolase (EC 4.1.2.21) compare
Pf1N1B4_2401 +0.6 1.4 Lipoprotein, putative compare
Pf1N1B4_4166 +0.6 1.7 Transcriptional regulator, LysR family compare
Pf1N1B4_5074 +0.6 1.6 Gluconate permease compare
Pf1N1B4_2173 +0.6 1.7 Diaminopimelate epimerase (EC 5.1.1.7) compare
Pf1N1B4_2350 +0.6 2.0 UPF0301 protein YqgE compare
Pf1N1B4_5790 +0.6 3.1 hypothetical protein compare
Pf1N1B4_4027 +0.6 1.6 hypothetical protein compare
Pf1N1B4_4699 +0.6 1.7 Multidrug translocase MdfA compare
Pf1N1B4_1670 +0.6 2.4 FIG001957: putative hydrolase compare
Pf1N1B4_4839 +0.6 1.7 lipoprotein compare
Pf1N1B4_4758 +0.6 2.0 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf1N1B4_5415 +0.6 2.2 hypothetical protein compare
Pf1N1B4_823 +0.6 1.1 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf1N1B4_4256 +0.6 1.4 Probable transmembrane protein compare
Pf1N1B4_4668 +0.6 2.0 Heavy metal RND efflux outer membrane protein, CzcC family compare
Pf1N1B4_5385 +0.6 2.0 hypothetical protein compare
Pf1N1B4_583 +0.6 0.7 FIG00957748: hypothetical protein compare
Pf1N1B4_3637 +0.6 2.1 FlhB domain protein compare
Pf1N1B4_4951 +0.6 1.8 Tryptophan synthase beta chain like (EC 4.2.1.20) compare
Pf1N1B4_4007 +0.6 1.6 sigma-54 dependent transcriptional regulator compare
Pf1N1B4_1523 +0.6 3.4 hypothetical protein compare
Pf1N1B4_4023 +0.6 2.1 hypothetical protein compare
Pf1N1B4_4555 +0.5 2.0 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) compare
Pf1N1B4_3074 +0.5 1.1 HesA/MoeB/ThiF family protein related to EC-YgdL compare
Pf1N1B4_1629 +0.5 2.1 FIG00958480: hypothetical protein compare
Pf1N1B4_2451 +0.5 2.2 Low-specificity L-threonine aldolase (EC 4.1.2.48) compare
Pf1N1B4_4819 +0.5 2.7 Multidrug resistance protein B compare
Pf1N1B4_1750 +0.5 1.0 Death on curing protein, Doc toxin compare
Pf1N1B4_846 +0.5 1.2 hypothetical protein compare
Pf1N1B4_255 +0.5 2.2 Free methionine-(R)-sulfoxide reductase, contains GAF domain compare
Pf1N1B4_3492 +0.5 1.6 DNA-3-methyladenine glycosylase (EC 3.2.2.20) compare
Pf1N1B4_4771 +0.5 0.9 Probable transmembrane protein compare
Pf1N1B4_5571 +0.5 1.9 hypothetical protein compare
Pf1N1B4_883 +0.5 1.1 Hypothetical nudix hydrolase YeaB compare
Pf1N1B4_5346 +0.5 1.4 hypothetical protein compare
Pf1N1B4_1741 +0.5 2.6 Ferredoxin reductase compare
Pf1N1B4_4008 +0.5 2.1 Various polyols ABC transporter, ATP-binding component compare
Pf1N1B4_5949 +0.5 0.9 Phosphomannomutase (EC 5.4.2.8) compare
Pf1N1B4_5321 +0.5 1.6 hypothetical protein compare
Pf1N1B4_2275 +0.5 2.6 Fumarylacetoacetate hydrolase family protein compare
Pf1N1B4_4271 +0.5 1.2 Hydrogen cyanide synthase HcnC / Opine oxidase subunit B compare
Pf1N1B4_16 +0.5 1.7 Cys regulon transcriptional activator CysB compare
Pf1N1B4_5463 +0.5 1.5 hypothetical protein compare
Pf1N1B4_4054 +0.5 2.7 ATP-dependent Clp protease adaptor protein ClpS compare
Pf1N1B4_2783 +0.5 1.3 Transcription elongation factor GreB-related protein compare
Pf1N1B4_741 +0.5 1.9 DNA-binding response regulator, LuxR family compare
Pf1N1B4_5262 +0.5 2.3 hypothetical protein compare
Pf1N1B4_3331 +0.5 1.5 Glycine cleavage system transcriptional antiactivator GcvR compare
Pf1N1B4_5634 +0.5 2.2 Acetoacetyl-CoA synthetase (EC 6.2.1.16) compare
Pf1N1B4_825 +0.5 1.2 tRNA (uridine-5-oxyacetic acid methyl ester) 34 synthase compare
Pf1N1B4_5380 +0.5 2.1 hypothetical protein compare
Pf1N1B4_2047 +0.5 1.9 Chorismate--pyruvate lyase (EC 4.1.3.40) compare
Pf1N1B4_681 +0.5 1.9 FOG: GGDEF domain compare
Pf1N1B4_4590 +0.5 1.4 Oligopeptide transport system permease protein OppB (TC 3.A.1.5.1) compare
Pf1N1B4_4644 +0.5 1.4 hypothetical protein compare
Pf1N1B4_3047 +0.5 2.0 Putative lipoprotein in cluster with COG2110 compare
Pf1N1B4_4918 +0.5 0.8 Predicted enzyme of the cupin superfamily compare
Pf1N1B4_4202 +0.5 2.4 4-oxalmesaconate hydratase (EC 4.2.1.83) compare
Pf1N1B4_1637 +0.5 1.2 FIG00954739: hypothetical protein compare
Pf1N1B4_5476 +0.5 1.2 hypothetical protein compare
Pf1N1B4_799 +0.5 1.0 hypothetical protein compare
Pf1N1B4_5278 +0.5 0.8 hypothetical protein compare
Pf1N1B4_3782 +0.5 1.2 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54) compare
Pf1N1B4_3546 +0.5 1.0 P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein compare
Pf1N1B4_1492 +0.5 1.0 FIG00959437: hypothetical protein compare
Pf1N1B4_560 +0.5 1.7 Transcriptional regulators, LysR family compare
Pf1N1B4_4582 +0.5 1.1 hypothetical protein compare
Pf1N1B4_756 +0.5 1.1 hypothetical protein compare
Pf1N1B4_4175 +0.5 1.9 Universal stress protein family 5 compare
Pf1N1B4_93 +0.5 1.6 Phenazine biosynthesis protein PhzF like compare
Pf1N1B4_5368 +0.5 2.5 hypothetical protein compare
Pf1N1B4_2865 +0.5 2.6 Rieske 2Fe-2S family protein compare
Pf1N1B4_5725 +0.5 1.2 High-affinity iron permease compare
Pf1N1B4_4505 +0.5 1.3 Coenzyme PQQ synthesis protein E compare
Pf1N1B4_72 +0.5 1.0 Transcriptional regulator, LysR family compare
Pf1N1B4_3692 +0.5 1.3 Chaperone protein HtpG compare
Pf1N1B4_3865 +0.5 1.9 Butyryl-CoA dehydrogenase (EC 1.3.99.2) compare
Pf1N1B4_2755 +0.5 2.3 Xanthine/uracil/thiamine/ascorbate permease family protein compare
Pf1N1B4_740 +0.5 1.0 Leucyl-tRNA synthetase compare
Pf1N1B4_5350 +0.5 1.7 hypothetical protein compare
Pf1N1B4_3168 +0.5 1.4 AmpG permease compare
Pf1N1B4_4560 +0.5 1.1 Transcriptional regulator, MerR family compare
Pf1N1B4_1336 +0.5 1.1 Putative multicopper oxidases compare
Pf1N1B4_2080 +0.5 1.6 hypothetical protein compare
Pf1N1B4_4831 +0.5 0.8 Outer membrane protein assembly factor YaeT precursor compare
Pf1N1B4_4540 +0.5 1.4 Uncharacterized protein ImpJ/VasE compare
Pf1N1B4_3519 +0.5 1.6 Lipase (EC 3.1.1.3) compare
Pf1N1B4_5433 +0.5 1.4 hypothetical protein compare
Pf1N1B4_37 +0.5 1.9 N-hydroxyarylamine O-acetyltransferase (EC 2.3.1.118) compare
Pf1N1B4_730 +0.5 2.0 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) compare
Pf1N1B4_5002 +0.5 1.8 Protein rarD compare
Pf1N1B4_2023 +0.5 2.7 L-asparaginase (EC 3.5.1.1) (from data) compare
Pf1N1B4_5106 +0.5 2.0 Dipeptide-binding ABC transporter, periplasmic substrate-binding component (TC 3.A.1.5.2); Putative hemin-binding lipoprotein compare
Pf1N1B4_4669 +0.5 0.9 Heavy metal RND efflux outer membrane protein, CzcC family compare
Pf1N1B4_2479 +0.5 1.3 Glycine cleavage system transcriptional antiactivator GcvR compare
Pf1N1B4_2492 +0.5 1.9 FIG00954771: hypothetical protein compare
Pf1N1B4_5779 +0.5 1.2 Nitrous oxide reductase maturation protein NosF (ATPase) compare
Pf1N1B4_153 +0.4 2.0 Glucoamylase (EC 3.2.1.3) compare
Pf1N1B4_1422 +0.4 1.6 hypothetical protein compare
Pf1N1B4_4086 +0.4 1.9 transcriptional regulator, LuxR family compare
Pf1N1B4_5270 +0.4 2.6 hypothetical protein compare
Pf1N1B4_71 +0.4 1.3 Glucarate dehydratase (EC 4.2.1.40) compare
Pf1N1B4_1189 +0.4 2.2 Predicted L-lactate dehydrogenase, hypothetical protein subunit YkgG compare
Pf1N1B4_1782 +0.4 1.1 hypothetical protein compare
Pf1N1B4_3126 +0.4 1.5 Phage tail length tape-measure protein compare
Pf1N1B4_34 +0.4 0.9 Xanthine permease compare
Pf1N1B4_4725 +0.4 1.6 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) compare
Pf1N1B4_5753 +0.4 1.4 putative membrane protein compare
Pf1N1B4_2793 +0.4 1.6 FKBP-type peptidyl-prolyl cis-trans isomerase FklB (EC 5.2.1.8) compare
Pf1N1B4_4478 +0.4 1.4 Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.168) compare
Pf1N1B4_2421 +0.4 1.2 L-proline glycine betaine ABC transport system permease protein ProW (TC 3.A.1.12.1) compare
Pf1N1B4_2318 +0.4 2.0 FIG229276: Transcriptional regulator, AraC family compare
Pf1N1B4_1481 +0.4 1.5 Protein involved in catabolism of external DNA compare
Pf1N1B4_1899 +0.4 1.8 Gfa-like protein compare
Pf1N1B4_1012 +0.4 2.3 Glycine cleavage system transcriptional activator compare
Pf1N1B4_2428 +0.4 2.4 FIG143042: Thioesterase-like protein compare
Pf1N1B4_3920 +0.4 1.3 Glycerophosphoryl diester phosphodiesterase (EC 3.1.4.46) compare
Pf1N1B4_2182 +0.4 2.2 Glutathione S-transferase N-terminal domain protein (EC 2.5.1.18) compare
Pf1N1B4_5266 +0.4 1.0 hypothetical protein compare
Pf1N1B4_5283 +0.4 1.1 hypothetical protein compare
Pf1N1B4_4778 +0.4 1.5 NADH pyrophosphatase (EC 3.6.1.22) compare
Pf1N1B4_798 +0.4 2.2 Polymyxin resistance protein ArnC, glycosyl transferase (EC 2.4.-.-) compare
Pf1N1B4_3561 +0.4 2.0 Xanthine transporter,putative compare
Pf1N1B4_1347 +0.4 1.7 Urea ABC transporter, ATPase protein UrtE compare
Pf1N1B4_2947 +0.4 2.0 Restriction endonuclease compare
Pf1N1B4_320 +0.4 1.9 3-oxoacyl-[acyl-carrier-protein] synthase, KASII (EC 2.3.1.179) compare
Pf1N1B4_614 +0.4 1.4 Arginine/ornithine antiporter ArcD compare
Pf1N1B4_1615 +0.4 1.7 Glutaredoxin 3 (Grx3) compare
Pf1N1B4_2679 +0.4 1.6 Nucleoside-diphosphate-sugar epimerases compare
Pf1N1B4_3804 +0.4 1.0 Glycine-rich cell wall structural protein precursor compare
Pf1N1B4_3253 +0.4 1.5 Acyl carrier protein phosphodiesterase (EC 3.1.4.14) compare
Pf1N1B4_1707 +0.4 1.5 Efflux membrane fusion protein, RND family compare
Pf1N1B4_3978 +0.4 1.7 Catalase (EC 1.11.1.6) compare
Pf1N1B4_3604 +0.4 2.0 Flagellar M-ring protein FliF compare
Pf1N1B4_567 +0.4 1.1 Histone acetyltransferase HPA2 and related acetyltransferases compare


Specific Phenotypes

For 2 genes in this experiment

For carbon source Sodium pyruvate in Pseudomonas fluorescens FW300-N1B4

For carbon source Sodium pyruvate across organisms