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Experiment set1IT035 for
Methanococcus maripaludis JJ
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Formate McCas, 2.5g/L bicarb, 200 mM MOPs, 20 psi N2CO2, SO4 FREE
200 most important genes:
gene
name
fitness
t score
description
MMJJ
_RS08855
-6.3
-3.8
cyclic pyranopterin monophosphate synthase MoaC
compare
MMJJ
_RS07665
-5.6
-29.9
formate dehydrogenase subunit alpha
compare
MMJJ
_RS06260
-5.5
-6.5
6-carboxyhexanoate--CoA ligase
compare
MMJJ
_RS07670
-5.4
-19.7
Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain
compare
MMJJ
_RS05155
-5.4
-3.7
5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH
compare
MMJJ
_RS08005
-5.3
-18.5
formate dehydrogenase accessory sulfurtransferase FdhD
compare
MMJJ
_RS03115
-5.1
-6.9
sulfopyruvate decarboxylase subunit alpha
compare
MMJJ
_RS03065
-5.1
-15.3
CBS domain-containing protein
compare
MMJJ
_RS07655
-5.1
-14.4
hypothetical protein
compare
MMJJ
_RS04595
-5.0
-6.0
hypothetical protein
compare
MMJJ
_RS02055
-5.0
-13.5
GTP 3',8-cyclase MoaA
compare
MMJJ
_RS06860
-4.9
-3.3
hypothetical protein
compare
MMJJ
_RS04485
-4.7
-10.0
riboflavin synthase
compare
MMJJ
_RS05535
-4.7
-11.7
hypothetical protein
compare
MMJJ
_RS00580
-4.6
-2.2
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG
compare
MMJJ
_RS08080
-4.6
-6.2
TIGR00300 family protein
compare
MMJJ
_RS07660
-4.5
-9.8
carbonic anhydrase
compare
MMJJ
_RS06725
-4.5
-9.5
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMJJ
_RS06915
-4.4
-17.9
helix-turn-helix domain-containing protein
compare
MMJJ
_RS00075
-4.3
-12.9
AAA family ATPase
compare
MMJJ
_RS00040
-4.3
-10.4
CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon
compare
MMJJ
_RS06510
-4.3
-3.0
LL-diaminopimelate aminotransferase
compare
MMJJ
_RS00450
-4.3
-2.4
DUF126 domain-containing protein
compare
MMJJ
_RS03055
-4.3
-2.7
hypothetical protein
compare
MMJJ
_RS07650
-4.2
-22.2
formate/nitrite transporter family protein
compare
MMJJ
_RS03920
-4.2
-18.3
nickel pincer cofactor biosynthesis protein LarC
compare
MMJJ
_RS07245
-4.2
-4.0
amidohydrolase family protein
compare
MMJJ
_RS00035
-4.2
-19.5
CO dehydrogenase/acetyl-CoA synthase complex subunit alpha
compare
MMJJ
_RS04200
-4.2
-5.7
triphosphoribosyl-dephospho-CoA synthase
compare
MMJJ
_RS08020
-4.1
-9.4
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS00645
-4.1
-11.7
adenosylmethionine--8-amino-7-oxononanoate transaminase
compare
MMJJ
_RS04800
-4.1
-2.8
2-phospho-L-lactate guanylyltransferase
compare
MMJJ
_RS05575
-4.1
-3.9
2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase
compare
MMJJ
_RS07640
-4.1
-24.4
cache domain-containing protein
compare
MMJJ
_RS06600
-4.1
-4.0
DUF555 domain-containing protein
compare
MMJJ
_RS00055
-4.0
-12.6
CO dehydrogenase/acetyl-CoA synthase subunit delta
compare
MMJJ
_RS01935
-4.0
-2.8
O-phosphoseryl-tRNA(Sec) selenium transferase
compare
MMJJ
_RS07975
-4.0
-12.5
ATP-dependent sacrificial sulfur transferase LarE
compare
MMJJ
_RS03895
-4.0
-3.8
hydrogenase expression/formation protein HypE
compare
MMJJ
_RS02045
-4.0
-2.7
molybdenum cofactor guanylyltransferase
compare
MMJJ
_RS06855
-4.0
-1.9
DUF2104 domain-containing protein
compare
MMJJ
_RS00050
-4.0
-9.9
AAA family ATPase
compare
MMJJ
_RS05445
-4.0
-2.7
2-oxoacid:acceptor oxidoreductase subunit alpha
compare
MMJJ
_RS08535
-4.0
-2.7
NOL1/NOP2/sun family putative RNA methylase
compare
MMJJ
_RS06155
-4.0
-5.3
phosphatidylglycerophosphatase A
compare
MMJJ
_RS00060
-4.0
-17.7
acetyl-CoA decarbonylase/synthase complex subunit gamma
compare
MMJJ
_RS00065
-4.0
-9.9
4Fe-4S dicluster domain-containing protein
compare
MMJJ
_RS00370
-3.9
-2.2
asparagine synthase (glutamine-hydrolyzing)
compare
MMJJ
_RS07720
-3.9
-2.1
UPF0058 family protein
compare
MMJJ
_RS08065
-3.9
-3.5
precorrin-6Y C5,15-methyltransferase (decarboxylating) subunit CbiT
compare
MMJJ
_RS04145
-3.9
-11.0
glutamate-1-semialdehyde 2,1-aminomutase
compare
MMJJ
_RS07980
-3.9
-13.9
biotin synthase BioB
compare
MMJJ
_RS08000
-3.9
-10.9
HesA/MoeB/ThiF family protein
compare
MMJJ
_RS08625
-3.9
-2.7
magnesium/cobalt transporter CorA
compare
MMJJ
_RS01750
-3.9
-2.6
ferrous iron transport protein A
compare
MMJJ
_RS00045
-3.9
-17.9
CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta
compare
MMJJ
_RS06375
-3.8
-3.7
UbiX family flavin prenyltransferase
compare
MMJJ
_RS03500
-3.8
-11.8
F420-dependent methylenetetrahydromethanopterin dehydrogenase
compare
MMJJ
_RS03620
-3.8
-4.4
DUF2097 domain-containing protein
compare
MMJJ
_RS00935
-3.8
-13.5
nickel pincer cofactor biosynthesis protein LarB
compare
MMJJ
_RS07160
-3.8
-20.8
M20 family metallo-hydrolase
compare
MMJJ
_RS06490
-3.7
-2.5
methanogenesis marker 2 protein
compare
MMJJ
_RS04155
-3.7
-3.6
hypothetical protein
compare
MMJJ
_RS07995
-3.7
-6.9
molybdenum cofactor biosynthesis protein MoaE
compare
MMJJ
_RS02200
-3.7
-7.4
chorismate pyruvate-lyase family protein
compare
MMJJ
_RS04685
-3.7
-7.3
carbamoyltransferase HypF
compare
MMJJ
_RS06240
-3.7
-3.4
dihydropteroate synthase-like protein
compare
MMJJ
_RS06270
-3.7
-9.0
dethiobiotin synthase
compare
MMJJ
_RS02090
-3.6
-2.5
tyramine--L-glutamate ligase
compare
MMJJ
_RS06265
-3.6
-14.9
8-amino-7-oxononanoate synthase
compare
MMJJ
_RS03150
-3.6
-4.3
2-phospho-L-lactate transferase
compare
MMJJ
_RS07635
-3.6
-13.5
response regulator transcription factor
compare
MMJJ
_RS00125
-3.6
-2.5
KEOPS complex subunit Cgi121
compare
MMJJ
_RS03865
-3.6
-1.6
phosphoribosyl-AMP cyclohydrolase
compare
MMJJ
_RS08095
-3.6
-3.4
cobyric acid synthase CobQ
compare
MMJJ
_RS09375
-3.6
-1.7
hypothetical protein
compare
MMJJ
_RS06875
-3.6
-2.2
hypothetical protein
compare
MMJJ
_RS03200
-3.5
-2.2
uroporphyrinogen-III synthase
compare
MMJJ
_RS05190
-3.5
-8.4
gamma carbonic anhydrase family protein
compare
MMJJ
_RS08035
-3.5
-9.1
cobalt-precorrin-7 (C(5))-methyltransferase
compare
MMJJ
_RS03270
-3.5
-1.9
ribosome biogenesis/translation initiation ATPase RLI
compare
MMJJ
_RS09135
-3.5
-11.3
archaeosine biosynthesis radical SAM protein RaSEA
compare
MMJJ
_RS06040
-3.5
-2.4
NADH-quinone oxidoreductase subunit H
compare
MMJJ
_RS04700
-3.4
-5.6
deoxyhypusine synthase
compare
MMJJ
_RS06930
-3.4
-3.1
type II methionyl aminopeptidase
compare
MMJJ
_RS02040
-3.4
-2.3
Asp-tRNA(Asn) amidotransferase subunit GatC
compare
MMJJ
_RS06175
-3.4
-2.1
DUF1743 domain-containing protein
compare
MMJJ
_RS03005
-3.4
-2.3
Ni-sirohydrochlorin a,c-diamide reductive cyclase catalytic subunit
compare
MMJJ
_RS00275
-3.4
-2.8
coenzyme F420-0:L-glutamate ligase
compare
MMJJ
_RS07950
-3.4
-2.3
4Fe-4S binding protein
compare
MMJJ
_RS05950
-3.4
-2.3
bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase
compare
MMJJ
_RS03125
-3.4
-5.0
GMC oxidoreductase
compare
MMJJ
_RS03060
-3.3
-3.8
methanogenesis marker 7 protein
compare
MMJJ
_RS03670
-3.3
-3.2
precorrin-2 C(20)-methyltransferase
compare
MMJJ
_RS00570
-3.3
-1.6
ribonuclease P
compare
MMJJ
_RS00205
-3.3
-4.9
adenosylcobinamide-phosphate synthase CbiB
compare
MMJJ
_RS04050
-3.3
-2.1
dihydroneopterin aldolase family protein
compare
MMJJ
_RS07725
-3.3
-7.3
DNA primase DnaG
compare
MMJJ
_RS04475
-3.3
-5.2
3,4-dihydroxy-2-butanone-4-phosphate synthase
compare
MMJJ
_RS06180
-3.2
-2.2
tryptophan--tRNA ligase
compare
MMJJ
_RS04650
-3.2
-5.2
nitrogenase iron protein
compare
MMJJ
_RS03170
-3.2
-7.7
DUF5612 domain-containing protein
compare
MMJJ
_RS03295
-3.2
-14.8
PHP domain-containing protein
compare
MMJJ
_RS05070
-3.2
-1.9
DNA primase catalytic subunit PriS
compare
MMJJ
_RS08795
-3.2
-2.1
phosphoglucosamine mutase
compare
MMJJ
_RS06010
-3.1
-6.0
hypothetical protein
compare
MMJJ
_RS06715
-3.1
-12.6
lactaldehyde dehydrogenase
compare
MMJJ
_RS07350
-3.1
-3.6
4Fe-4S binding protein
compare
MMJJ
_RS04995
-3.1
-5.1
Tfx family DNA-binding protein
compare
MMJJ
_RS00070
-3.1
-2.9
CooT family nickel-binding protein
compare
MMJJ
_RS08340
-3.1
-5.0
archaeoflavoprotein AfpA
compare
MMJJ
_RS06700
-3.1
-5.8
L-seryl-tRNA(Sec) kinase
compare
MMJJ
_RS06695
-3.1
-2.1
amidohydrolase
compare
MMJJ
_RS05065
-3.1
-4.7
(4-{4-[2-(gamma-L- glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase
compare
MMJJ
_RS01600
-3.1
-2.1
radical SAM protein
compare
MMJJ
_RS06485
-3.1
-2.9
phosphoglycerate kinase
compare
MMJJ
_RS03110
-3.1
-3.5
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase
compare
MMJJ
_RS05995
-3.0
-2.5
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS06215
-3.0
-4.1
agmatinase
compare
MMJJ
_RS09190
-3.0
-2.0
tryptophan synthase subunit beta
compare
MMJJ
_RS05260
-3.0
-4.9
ATP-grasp domain-containing protein
compare
MMJJ
_RS07360
-3.0
-1.4
TIGR00269 family protein
compare
MMJJ
_RS08330
-3.0
-3.4
SufD family Fe-S cluster assembly protein
compare
MMJJ
_RS00560
-3.0
-3.5
homoisocitrate dehydrogenase
compare
MMJJ
_RS08155
-3.0
-4.0
cobalt-precorrin-5B (C(1))-methyltransferase CbiD
compare
MMJJ
_RS06625
-3.0
-1.6
pyruvate synthase subunit PorB
compare
MMJJ
_RS00080
-3.0
-12.0
DUF166 domain-containing protein
compare
MMJJ
_RS06255
-3.0
-4.8
tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3
compare
MMJJ
_RS01350
-3.0
-7.1
sodium:proton antiporter
compare
MMJJ
_RS05490
-3.0
-2.0
imidazole glycerol phosphate synthase subunit HisF
compare
MMJJ
_RS03310
-2.9
-2.8
hypothetical protein
compare
MMJJ
_RS06220
-2.9
-5.7
polyamine aminopropyltransferase
compare
MMJJ
_RS08840
-2.9
-4.7
calcium/sodium antiporter
compare
MMJJ
_RS08010
-2.9
-6.9
phosphoadenosine phosphosulfate reductase family protein
compare
MMJJ
_RS06760
-2.9
-2.8
Ni-sirohydrochlorin a,c-diamide synthase
compare
MMJJ
_RS05540
-2.9
-18.7
LysR family transcriptional regulator
compare
MMJJ
_RS03580
-2.9
-3.8
TIGR00303 family protein
compare
MMJJ
_RS07355
-2.9
-5.7
MoaD/ThiS family protein
compare
MMJJ
_RS03190
-2.9
-2.0
phosphopyruvate hydratase
compare
MMJJ
_RS01360
-2.9
-1.9
UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
compare
MMJJ
_RS06390
-2.9
-1.6
NADPH-dependent F420 reductase
compare
MMJJ
_RS02920
-2.9
-2.6
30S ribosomal protein S27ae
compare
MMJJ
_RS05720
-2.9
-1.9
glutamine--fructose-6-phosphate transaminase (isomerizing)
compare
MMJJ
_RS06015
-2.9
-11.9
Na(+)/H(+) antiporter subunit B
compare
MMJJ
_RS03615
-2.9
-1.9
cobalt-precorrin-8 methylmutase
compare
MMJJ
_RS06840
-2.8
-1.9
nickel-dependent hydrogenase large subunit
compare
MMJJ
_RS08320
-2.8
-2.3
CDP-diacylglycerol--serine O-phosphatidyltransferase
compare
MMJJ
_RS07155
-2.8
-10.5
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMJJ
_RS05935
-2.8
-2.2
Era-like GTP-binding protein
compare
MMJJ
_RS03490
-2.8
-2.7
ribonuclease VapC
compare
MMJJ
_RS04150
-2.8
-3.6
DUF5379 domain-containing protein
compare
MMJJ
_RS04790
-2.8
-4.4
biotin--[acetyl-CoA-carboxylase] ligase
compare
MMJJ
_RS05930
-2.8
-1.7
cell division protein SepF
compare
MMJJ
_RS06050
-2.8
-8.0
molybdopterin molybdotransferase MoeA
compare
MMJJ
_RS06020
-2.8
-7.3
hypothetical protein
compare
MMJJ
_RS03230
-2.8
-4.4
NAD(P)/FAD-dependent oxidoreductase
compare
MMJJ
_RS07430
-2.8
-3.8
ribonuclease VapC
compare
MMJJ
_RS06005
-2.7
-10.0
energy conserving hydrogenase EhbF
compare
MMJJ
_RS00475
-2.7
-1.9
bifunctional ornithine acetyltransferase/N-acetylglutamate synthase
compare
MMJJ
_RS03765
-2.7
-9.6
hypothetical protein
compare
MMJJ
_RS08250
-2.7
-6.2
hydrogenase maturation peptidase HycI
compare
MMJJ
_RS07470
-2.7
-2.3
50S ribosome-binding GTPase
compare
MMJJ
_RS05415
-2.7
-1.7
hypothetical protein
compare
MMJJ
_RS02190
-2.7
-12.9
molybdopterin biosynthesis protein
compare
MMJJ
_RS00270
-2.7
-2.5
adenosylcobinamide-GDP ribazoletransferase
compare
MMJJ
_RS03875
-2.7
-4.2
CBS domain-containing protein
compare
MMJJ
_RS05375
-2.6
-14.2
radical SAM protein
compare
MMJJ
_RS05370
-2.6
-9.6
LysR family transcriptional regulator
compare
MMJJ
_RS02935
-2.6
-2.9
DNA-directed RNA polymerase subunit E''
compare
MMJJ
_RS07190
-2.6
-3.0
RtcB family protein
compare
MMJJ
_RS01860
-2.6
-14.1
tRNA guanosine(15) transglycosylase TgtA
compare
MMJJ
_RS04505
-2.6
-7.7
CDC48 family AAA ATPase
compare
MMJJ
_RS01865
-2.6
-6.4
peptidyl-tRNA hydrolase Pth2
compare
MMJJ
_RS04520
-2.6
-5.5
coenzyme F430 synthase
compare
MMJJ
_RS09130
-2.6
-1.4
NFYB/HAP3 family transcription factor subunit
compare
MMJJ
_RS05330
-2.6
-1.7
DNA polymerase II large subunit
compare
MMJJ
_RS04975
-2.6
-2.1
glycosyltransferase family 4 protein
compare
MMJJ
_RS06225
-2.5
-1.6
adenosylmethionine decarboxylase
compare
MMJJ
_RS01880
-2.5
-2.8
RlmE family RNA methyltransferase
compare
MMJJ
_RS05810
-2.5
-4.7
precorrin-4 C(11)-methyltransferase
compare
MMJJ
_RS06025
-2.5
-15.3
4Fe-4S binding protein
compare
MMJJ
_RS02275
-2.5
-4.0
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS06000
-2.5
-4.1
cation:proton antiporter subunit C
compare
MMJJ
_RS07705
-2.5
-1.7
GTP-binding protein EngB
compare
MMJJ
_RS06905
-2.5
-2.4
hypothetical protein
compare
MMJJ
_RS04125
-2.5
-10.9
tRNA (guanine(10)-N(2))-dimethyltransferase
compare
MMJJ
_RS09175
-2.5
-1.0
anthranilate synthase component I
compare
MMJJ
_RS01200
-2.5
-1.7
PRC-barrel domain-containing protein
compare
MMJJ
_RS07410
-2.5
-3.3
methanogenesis marker protein Mmp4/MtxX
compare
MMJJ
_RS03225
-2.5
-3.3
4Fe-4S binding protein
compare
MMJJ
_RS04730
-2.5
-1.7
tyrosine decarboxylase MfnA
compare
MMJJ
_RS07785
-2.5
-2.3
fumarate reductase subunit A
compare
MMJJ
_RS03760
-2.5
-3.4
hydrogenase maturation nickel metallochaperone HypA
compare
MMJJ
_RS04675
-2.5
-6.8
thiamine pyrophosphate-binding protein
compare
MMJJ
_RS08870
-2.4
-1.3
2-isopropylmalate synthase
compare
MMJJ
_RS06035
-2.4
-9.6
NADH-quinone oxidoreductase subunit B family protein
compare
MMJJ
_RS06110
-2.4
-2.2
bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC
compare
MMJJ
_RS06910
-2.4
-1.6
energy-converting NiFe hydrogenase A subunit EhaA
compare
MMJJ
_RS05620
-2.4
-2.3
CoB--CoM heterodisulfide reductase iron-sulfur subunit A family protein
compare
MMJJ
_RS03095
-2.4
-2.2
bifunctional N(6)-L-threonylcarbamoyladenine synthase/serine/threonine protein kinase
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis JJ in rich t2 experiments