Experiment set1IT034 for Pseudomonas fluorescens FW300-N2E2

Compare to:

Sodium octanoate carbon source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_3060 -7.6 -3.5 Outer membrane protein H precursor compare
Pf6N2E2_4414 -7.0 -4.1 FIG00953808: hypothetical protein compare
Pf6N2E2_3610 -6.8 -6.6 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_4764 -6.5 -7.7 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_3666 -6.2 -5.7 InaA protein compare
Pf6N2E2_64 -6.0 -3.8 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_4597 -6.0 -12.8 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_3630 -6.0 -8.2 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_4071 -5.9 -6.4 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_71 -5.8 -7.9 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_4762 -5.7 -3.8 Biotin synthesis protein BioH compare
Pf6N2E2_2872 -5.7 -13.3 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) compare
Pf6N2E2_3842 -5.6 -6.0 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_3770 -5.5 -3.6 ATP-dependent hsl protease ATP-binding subunit HslU compare
Pf6N2E2_3941 -5.5 -3.8 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf6N2E2_5527 -5.5 -3.2 Cold shock protein CspC compare
Pf6N2E2_3751 -5.5 -17.3 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_4826 -5.5 -8.7 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_4596 -5.5 -11.2 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_4761 -5.4 -14.8 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf6N2E2_4075 -5.3 -5.2 Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1) compare
Pf6N2E2_4047 -5.3 -7.3 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_5176 -5.3 -13.6 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_5014 -5.3 -1.4 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_279 -5.2 -11.6 Isocitrate lyase (EC 4.1.3.1) compare
Pf6N2E2_4759 -5.2 -19.6 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_5153 -5.2 -9.3 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) compare
Pf6N2E2_3783 -5.1 -7.6 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_4074 -5.1 -19.4 Phosphate transport system permease protein PstC (TC 3.A.1.7.1) compare
Pf6N2E2_4763 -5.0 -12.9 Biotin synthesis protein BioC compare
Pf6N2E2_3782 -5.0 -6.8 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_5175 -5.0 -17.9 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_4279 -5.0 -16.8 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_3899 -5.0 -12.6 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) compare
Pf6N2E2_3264 -4.9 -3.2 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_2073 -4.9 -8.2 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_2261 -4.9 -5.8 VacJ-like lipoprotein precursor compare
Pf6N2E2_6140 -4.8 -1.3 Large Subunit Ribosomal RNA; lsuRNA; LSU rRNA compare
Pf6N2E2_66 -4.8 -12.4 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_4825 -4.8 -12.6 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_2217 -4.8 -8.0 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_3932 -4.8 -9.0 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_3248 -4.8 -4.8 Probable transmembrane protein compare
Pf6N2E2_2474 -4.7 -12.0 ErfK/YbiS/YcfS/YnhG family protein compare
Pf6N2E2_37 -4.7 -5.6 6-carboxytetrahydropterin synthase (EC 4.1.2.50) @ Queuosine biosynthesis QueD, PTPS-I compare
Pf6N2E2_3253 -4.7 -7.8 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_3885 -4.7 -4.6 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
Pf6N2E2_5177 -4.6 -11.6 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_88 -4.6 -1.7 hypothetical protein compare
Pf6N2E2_2514 -4.5 -7.1 regulator of length of O-antigen component of lipopolysaccharide chains compare
Pf6N2E2_2074 -4.4 -1.7 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_5340 -4.4 -4.3 Stringent starvation protein A compare
Pf6N2E2_2752 -4.4 -12.4 Exported zinc metalloprotease YfgC precursor compare
Pf6N2E2_4769 -4.4 -23.5 Acyl-CoA dehydrogenase (EC 1.3.8.7) conserved
Pf6N2E2_77 -4.4 -5.3 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_302 -4.3 -8.8 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_2753 -4.3 -4.0 HtrA protease/chaperone protein compare
Pf6N2E2_2022 -4.3 -7.0 BarA-associated response regulator UvrY (= GacA = SirA) compare
Pf6N2E2_4599 -4.3 -5.2 Integral membrane protein YggT, involved in response to extracytoplasmic stress (osmotic shock) compare
Pf6N2E2_4048 -4.3 -8.2 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_5720 -4.3 -14.2 BarA sensory histidine kinase (= VarS = GacS) compare
Pf6N2E2_4278 -4.2 -11.4 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_4752 -4.2 -12.4 Malate synthase G (EC 2.3.3.9) compare
Pf6N2E2_3752 -4.2 -20.6 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_5219 -4.2 -9.6 FIG140336: TPR domain protein compare
Pf6N2E2_5553 -4.2 -9.2 Quinolinate synthetase (EC 2.5.1.72) compare
Pf6N2E2_3260 -4.2 -7.9 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
Pf6N2E2_50 -4.2 -7.8 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_2274 -4.1 -8.4 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) compare
Pf6N2E2_5723 -4.1 -13.6 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
Pf6N2E2_4638 -4.1 -5.6 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_2825 -4.1 -6.2 RND efflux system, outer membrane lipoprotein CmeC compare
Pf6N2E2_5671 -4.1 -5.4 Succinylglutamate desuccinylase (EC 3.5.1.96) compare
Pf6N2E2_5328 -4.0 -5.7 FIG00958649: hypothetical protein compare
Pf6N2E2_3349 -4.0 -3.6 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_4418 -4.0 -1.1 Diaminopimelate epimerase (EC 5.1.1.7) compare
Pf6N2E2_2574 -4.0 -3.3 Flagellar synthesis regulator FleN compare
Pf6N2E2_5536 -4.0 -2.1 Holliday junction DNA helicase RuvA compare
Pf6N2E2_4072 -3.9 -7.0 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
Pf6N2E2_3839 -3.9 -6.2 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_4453 -3.9 -15.0 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_634 -3.8 -12.3 NAD-specific glutamate dehydrogenase (EC 1.4.1.2), large form conserved
Pf6N2E2_4631 -3.8 -9.4 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf6N2E2_2219 -3.8 -3.0 Cell division trigger factor (EC 5.2.1.8) compare
Pf6N2E2_3258 -3.7 -7.6 Uncharacterized ABC transporter, periplasmic component YrbD compare
Pf6N2E2_5406 -3.7 -3.7 FIG00958224: hypothetical protein compare
Pf6N2E2_3841 -3.7 -5.9 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_5006 -3.7 -9.0 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_4564 -3.6 -8.8 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_3940 -3.6 -10.4 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_3252 -3.6 -7.8 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_1545 -3.5 -5.3 N-carbamoylputrescine amidase (EC 3.5.1.53) compare
Pf6N2E2_3346 -3.5 -5.5 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf6N2E2_4277 -3.5 -10.5 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_4187 -3.5 -5.7 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_3835 -3.4 -3.7 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf6N2E2_5242 -3.4 -3.0 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_2471 -3.3 -9.0 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_4073 -3.3 -6.6 Phosphate transport system permease protein PstA (TC 3.A.1.7.1) compare
Pf6N2E2_3611 -3.3 -2.0 HflC protein compare
Pf6N2E2_3672 -3.3 -10.9 Glutamate-ammonia-ligase adenylyltransferase (EC 2.7.7.42) compare
Pf6N2E2_5342 -3.3 -4.0 21 kDa hemolysin precursor compare
Pf6N2E2_4276 -3.3 -6.6 Phosphogluconate repressor HexR, RpiR family compare
Pf6N2E2_3762 -3.2 -6.5 NADP-dependent malic enzyme (EC 1.1.1.40) compare
Pf6N2E2_6057 -3.2 -3.6 FIG002781: Alpha-L-glutamate ligase family protein compare
Pf6N2E2_2218 -3.2 -5.2 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_3251 -3.2 -9.8 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_5178 -3.2 -2.6 CDP-diacylglycerol--serine O-phosphatidyltransferase (EC 2.7.8.8) compare
Pf6N2E2_5183 -3.1 -13.2 Paraquat-inducible protein B compare
Pf6N2E2_4077 -3.1 -2.7 cytosolic long-chain acyl-CoA thioester hydrolase family protein compare
Pf6N2E2_5780 -3.1 -8.6 Periplasmic protease compare
Pf6N2E2_2277 -3.1 -3.3 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_5181 -3.1 -10.7 Paraquat-inducible protein A compare
Pf6N2E2_2510 -3.1 -6.1 Lipid carrier : UDP-N-acetylgalactosaminyltransferase (EC 2.4.1.-) / Alpha-1,3-N-acetylgalactosamine transferase PglA (EC 2.4.1.-); Putative glycosyltransferase compare
Pf6N2E2_5727 -3.0 -6.0 FIG00955360: hypothetical protein compare
Pf6N2E2_2465 -3.0 -6.1 Cys regulon transcriptional activator CysB compare
Pf6N2E2_1876 -3.0 -3.3 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) compare
Pf6N2E2_288 -2.9 -2.7 Isocitrate dehydrogenase [NADP] (EC 1.1.1.42); Monomeric isocitrate dehydrogenase [NADP] (EC 1.1.1.42) compare
Pf6N2E2_2473 -2.9 -1.5 Major outer membrane lipoprotein I compare
Pf6N2E2_4417 -2.9 -3.7 Protein of unknown function DUF484 compare
Pf6N2E2_2722 -2.9 -4.6 FIG00954807: hypothetical protein compare
Pf6N2E2_280 -2.8 -4.1 hypothetical protein compare
Pf6N2E2_4150 -2.8 -3.7 probable exported protein YPO0432 compare
Pf6N2E2_2758 -2.8 -13.5 L-aspartate oxidase (EC 1.4.3.16) compare
Pf6N2E2_5545 -2.8 -5.1 Queuosine Biosynthesis QueE Radical SAM compare
Pf6N2E2_2340 -2.8 -3.8 Transcriptional regulator, GntR family compare
Pf6N2E2_2823 -2.8 -4.4 Multidrug efflux RND membrane fusion protein MexC compare
Pf6N2E2_5728 -2.8 -4.7 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_4766 -2.7 -12.1 Acyl-CoA dehydrogenase (EC 1.3.8.7) conserved
Pf6N2E2_1636 -2.7 -8.5 Ferrichrome-iron receptor compare
Pf6N2E2_4365 -2.6 -5.7 Ribonuclease PH (EC 2.7.7.56) compare
Pf6N2E2_3382 -2.6 -6.1 Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF compare
Pf6N2E2_5733 -2.6 -5.0 NLP/P60 family protein compare
Pf6N2E2_4160 -2.6 -1.5 Cytochrome c5 compare
Pf6N2E2_5150 -2.6 -5.2 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf6N2E2_2756 -2.6 -6.3 RNA polymerase sigma-H factor AlgT compare
Pf6N2E2_2824 -2.5 -8.0 RND efflux system, inner membrane transporter CmeB compare
Pf6N2E2_2258 -2.5 -10.1 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_248 -2.5 -5.9 hypothetical protein compare
Pf6N2E2_5345 -2.5 -6.5 LppC putative lipoprotein compare
Pf6N2E2_5579 -2.5 -6.0 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_3933 -2.5 -7.9 D-2-hydroxyglutarate dehydrogenase compare
Pf6N2E2_2391 -2.5 -8.4 FIG137360: hypothetical protein conserved
Pf6N2E2_4372 -2.4 -7.0 FIG00460773: hypothetical protein compare
Pf6N2E2_2264 -2.4 -4.0 NADPH dependent preQ0 reductase (EC 1.7.1.13) compare
Pf6N2E2_2064 -2.4 -3.5 Cobalt-precorrin-3b C17-methyltransferase compare
Pf6N2E2_5182 -2.4 -4.3 Paraquat-inducible protein A compare
Pf6N2E2_4272 -2.4 -3.5 putative membrane protein compare
Pf6N2E2_3351 -2.4 -4.3 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
Pf6N2E2_3257 -2.4 -4.1 Uncharacterized ABC transporter, auxiliary component YrbC compare
Pf6N2E2_5584 -2.4 -3.0 Bacterioferritin-associated ferredoxin compare
Pf6N2E2_3170 -2.4 -6.1 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_1169 -2.4 -2.5 TnpR protein compare
Pf6N2E2_1040 -2.3 -1.4 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
Pf6N2E2_2973 -2.3 -3.5 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_5494 -2.3 -4.3 Pyruvate kinase (EC 2.7.1.40) compare
Pf6N2E2_5425 -2.3 -1.6 hypothetical protein compare
Pf6N2E2_4454 -2.3 -5.2 Exopolyphosphatase (EC 3.6.1.11) compare
Pf6N2E2_3942 -2.2 -6.0 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
Pf6N2E2_2879 -2.2 -4.6 membrane protein, putative conserved
Pf6N2E2_3637 -2.2 -7.1 yqiA-like hydrolase, affects the cell envelope (from data) conserved
Pf6N2E2_5950 -2.2 -4.2 Phosphate:acyl-ACP acyltransferase PlsX compare
Pf6N2E2_4987 -2.1 -1.2 MaoC-like domain protein compare
Pf6N2E2_3984 -2.1 -6.6 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_2472 -2.1 -2.8 hypothetical protein compare
Pf6N2E2_2506 -2.1 -7.6 nucleotide sugar epimerase/dehydratase WbpM compare
Pf6N2E2_5738 -2.1 -6.6 Cobyrinic acid A,C-diamide synthase compare
Pf6N2E2_2938 -2.1 -4.5 Outer membrane lipoprotein compare
Pf6N2E2_4206 -2.0 -2.2 Chromosome (plasmid) partitioning protein ParB compare
Pf6N2E2_6059 -2.0 -3.8 FIG008443: hypothetical protein compare
Pf6N2E2_2488 -2.0 -2.0 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_3532 -2.0 -6.2 Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130) compare
Pf6N2E2_5312 -2.0 -1.2 FIG00964214: hypothetical protein compare
Pf6N2E2_477 -2.0 -4.5 Branched-chain amino acid aminotransferase (EC 2.6.1.42) compare
Pf6N2E2_4773 -2.0 -1.0 Coenzyme PQQ synthesis protein D compare
Pf6N2E2_3833 -2.0 -4.5 hypothetical protein compare
Pf6N2E2_3199 -2.0 -5.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase (EC 5.-.-.-) compare
Pf6N2E2_1293 -2.0 -2.2 COG2879, Hypothetical small protein yjiX compare
Pf6N2E2_2878 -2.0 -4.1 required for 4-hydroxybenzoate and octanoate transport, together with MFP and FUSC proteins (Pf6N2E2_2877, Pf6N2E2_2879) (from data) conserved
Pf6N2E2_1482 -1.9 -4.1 Probable periplasmic spermidine/putrescine-binding protein compare
Pf6N2E2_2877 -1.9 -7.0 Membrane fusion component of tripartite multidrug resistance system conserved
Pf6N2E2_2381 -1.9 -3.0 Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_1617 -1.9 -1.1 COG2199: FOG: GGDEF domain compare
Pf6N2E2_5714 -1.9 -2.6 Flavoprotein WrbA compare
Pf6N2E2_1981 -1.9 -4.4 FIG051360: Periplasmic protein TonB, links inner and outer membranes compare
Pf6N2E2_5613 -1.9 -2.3 FIG00953674: hypothetical protein compare
Pf6N2E2_3095 -1.9 -1.3 hypothetical protein compare
Pf6N2E2_3381 -1.9 -5.4 Predicted L-lactate dehydrogenase, Fe-S oxidoreductase subunit YkgE compare
Pf6N2E2_828 -1.9 -4.4 Transcriptional regulator, TetR family compare
Pf6N2E2_4204 -1.9 -1.7 rRNA small subunit 7-methylguanosine (m7G) methyltransferase GidB compare
Pf6N2E2_1249 -1.9 -3.9 Transcriptional regulator, AraC family compare
Pf6N2E2_2675 -1.8 -1.0 ATP-dependent RNA helicase SrmB compare
Pf6N2E2_5669 -1.8 -4.4 Succinylarginine dihydrolase (EC 3.5.3.23) compare
Pf6N2E2_5190 -1.8 -7.8 Carbonic anhydrase (EC 4.2.1.1) compare
Pf6N2E2_204 -1.8 -1.3 hypothetical protein compare
Pf6N2E2_5679 -1.8 -2.9 hypothetical protein compare
Pf6N2E2_5990 -1.8 -2.5 Translation initiation factor 2 (IF-2; GTPase) compare
Pf6N2E2_3642 -1.8 -5.2 lipoprotein, putative conserved
Pf6N2E2_2586 -1.8 -1.7 Hpt domain protein compare
Pf6N2E2_600 -1.8 -1.8 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases compare


Specific Phenotypes

For 14 genes in this experiment

For carbon source Sodium octanoate in Pseudomonas fluorescens FW300-N2E2

For carbon source Sodium octanoate across organisms