Experiment set1IT034 for Pseudomonas fluorescens FW300-N1B4

Compare to:

Sodium D,L-Lactate carbon source

200 most important genes:

  gene name fitness t score description  
Pf1N1B4_6 -4.0 -5.4 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf1N1B4_1307 -3.8 -2.6 3-dehydroquinate dehydratase II (EC 4.2.1.10) compare
Pf1N1B4_2880 -3.7 -12.8 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf1N1B4_1831 -3.5 -12.3 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf1N1B4_1533 -3.5 -7.7 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf1N1B4_1627 -3.4 -5.1 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf1N1B4_2549 -3.4 -10.7 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf1N1B4_5666 -3.3 -4.3 Oxidoreductase probably involved in sulfite reduction compare
Pf1N1B4_1189 -3.2 -5.7 Predicted L-lactate dehydrogenase, hypothetical protein subunit YkgG compare
Pf1N1B4_2545 -3.2 -14.6 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
Pf1N1B4_2009 -3.2 -5.6 LysR family transcriptional regulator PA5437 compare
Pf1N1B4_1534 -3.2 -18.5 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf1N1B4_1624 -3.0 -9.3 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf1N1B4_1067 -3.0 -5.6 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf1N1B4_742 -3.0 -9.4 Argininosuccinate synthase (EC 6.3.4.5) compare
Pf1N1B4_2303 -3.0 -15.1 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf1N1B4_2338 -3.0 -9.2 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf1N1B4_2858 -3.0 -11.9 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf1N1B4_5665 -3.0 -6.2 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf1N1B4_1434 -2.9 -8.6 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf1N1B4_3812 -2.8 -8.9 Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) compare
Pf1N1B4_2547 -2.8 -3.8 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
Pf1N1B4_1565 -2.8 -5.0 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf1N1B4_3506 -2.8 -8.6 Cysteine synthase B (EC 2.5.1.47) compare
Pf1N1B4_1188 -2.8 -11.0 Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF conserved
Pf1N1B4_15 -2.8 -4.5 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf1N1B4_1315 -2.7 -8.5 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) compare
Pf1N1B4_2384 -2.7 -10.4 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf1N1B4_2548 -2.7 -7.1 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf1N1B4_2010 -2.7 -6.6 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf1N1B4_1830 -2.7 -9.2 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf1N1B4_2879 -2.6 -7.8 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf1N1B4_1408 -2.6 -5.2 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf1N1B4_1187 -2.6 -7.2 Predicted L-lactate dehydrogenase, Fe-S oxidoreductase subunit YkgE conserved
Pf1N1B4_2272 -2.6 -4.9 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf1N1B4_350 -2.6 -7.9 Chorismate mutase I (EC 5.4.99.5) / Prephenate dehydratase (EC 4.2.1.51) compare
Pf1N1B4_5371 -2.6 -3.0 hypothetical protein compare
Pf1N1B4_12 -2.6 -7.8 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf1N1B4_2011 -2.6 -9.0 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf1N1B4_2282 -2.4 -9.1 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf1N1B4_3697 -2.4 -9.1 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf1N1B4_1186 -2.4 -10.1 L-lactate permease conserved
Pf1N1B4_1626 -2.3 -7.7 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf1N1B4_4065 -2.3 -8.1 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf1N1B4_2337 -2.3 -5.8 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf1N1B4_847 -2.2 -7.9 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf1N1B4_3917 -2.2 -5.1 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf1N1B4_1625 -2.1 -4.6 FIG00956267: hypothetical protein compare
Pf1N1B4_2878 -2.1 -8.7 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf1N1B4_3518 -2.1 -3.6 Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) compare
Pf1N1B4_1535 -2.1 -3.9 hypothetical protein compare
Pf1N1B4_1617 -2.1 -7.8 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (EC 5.4.2.1) compare
Pf1N1B4_762 -2.0 -6.6 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf1N1B4_2859 -2.0 -12.6 Two-component sensor CbrA: intrcellular carbon:nitrogen balance compare
Pf1N1B4_2112 -1.9 -12.4 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
Pf1N1B4_1906 -1.9 -4.0 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) compare
Pf1N1B4_5512 -1.8 -2.3 hypothetical protein compare
Pf1N1B4_2280 -1.7 -7.8 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf1N1B4_716 -1.7 -4.1 Probable thiol oxidoreductase with 2 cytochrome c heme-binding sites compare
Pf1N1B4_2682 -1.6 -2.5 Antiholin-like protein LrgA compare
Pf1N1B4_257 -1.6 -5.9 sensor histidine kinase/response regulator compare
Pf1N1B4_1057 -1.6 -3.2 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf1N1B4_1 -1.6 -2.1 Colicin V production protein compare
Pf1N1B4_3081 -1.5 -12.9 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
Pf1N1B4_2874 -1.5 -2.2 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) compare
Pf1N1B4_652 -1.5 -7.8 Sensory box histidine kinase compare
Pf1N1B4_3451 -1.5 -3.5 Aspartokinase (EC 2.7.2.4) compare
Pf1N1B4_1190 -1.5 -7.9 Predicted D-lactate dehydrogenase, Fe-S protein, FAD/FMN-containing conserved
Pf1N1B4_5359 -1.4 -3.0 hypothetical protein compare
Pf1N1B4_365 -1.3 -4.5 Cell division protein BolA compare
Pf1N1B4_3396 -1.3 -2.6 Protein export cytoplasm protein SecA ATPase RNA helicase (TC 3.A.5.1.1) compare
Pf1N1B4_2975 -1.3 -1.9 Peptide methionine sulfoxide reductase MsrB (EC 1.8.4.12) compare
Pf1N1B4_2176 -1.3 -2.6 Frataxin homolog CyaY, facilitates iron supply for heme A synthesis or Fe-S cluster assembly compare
Pf1N1B4_3795 -1.3 -1.8 3-ketoacyl-CoA thiolase (EC 2.3.1.16) @ Acetyl-CoA acetyltransferase (EC 2.3.1.9) compare
Pf1N1B4_1317 -1.3 -2.6 Sensor histidine kinase/response regulator compare
Pf1N1B4_1113 -1.3 -5.0 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf1N1B4_5834 -1.3 -2.8 Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B (EC 2.8.3.5) compare
Pf1N1B4_1975 -1.3 -2.7 Transcriptional regulator, AsnC family compare
Pf1N1B4_578 -1.3 -2.2 enoyl-CoA hydratase, R-specific compare
Pf1N1B4_5330 -1.2 -1.8 hypothetical protein compare
Pf1N1B4_5329 -1.2 -2.9 hypothetical protein compare
Pf1N1B4_3538 -1.2 -2.0 Transcriptional regulator, AraC family compare
Pf1N1B4_5357 -1.2 -1.3 hypothetical protein compare
Pf1N1B4_715 -1.2 -4.0 Iron-regulated protein A precursor compare
Pf1N1B4_5289 -1.2 -1.8 hypothetical protein compare
Pf1N1B4_3751 -1.2 -2.1 FIG00953060: hypothetical protein compare
Pf1N1B4_1837 -1.2 -1.7 Osmotically inducible protein C compare
Pf1N1B4_1566 -1.2 -4.4 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf1N1B4_348 -1.2 -3.1 Cyclohexadienyl dehydrogenase (EC 1.3.1.12)(EC 1.3.1.43) / 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19) compare
Pf1N1B4_2487 -1.2 -6.2 Biotin synthase (EC 2.8.1.6) compare
Pf1N1B4_2568 -1.2 -2.8 Translation elongation factor Tu compare
Pf1N1B4_5219 -1.2 -2.7 tRNA-Gly-CCC compare
Pf1N1B4_2684 -1.1 -2.3 Uncharacterized protein, similar to the N-terminal domain of Lon protease compare
Pf1N1B4_4857 -1.1 -4.2 Chemotaxis protein methyltransferase CheR (EC 2.1.1.80) compare
Pf1N1B4_1653 -1.1 -5.2 Branched-chain amino acid transport protein AzlC compare
Pf1N1B4_2377 -1.1 -5.1 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf1N1B4_35 -1.1 -2.7 hypothetical protein compare
Pf1N1B4_2857 -1.1 -2.9 Poly(A) polymerase (EC 2.7.7.19) compare
Pf1N1B4_219 -1.1 -3.2 Acyclic terpenes utilization regulator AtuR, TetR family compare
Pf1N1B4_4544 -1.1 -1.8 Uncharacterized protein ImpA compare
Pf1N1B4_2488 -1.1 -5.4 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf1N1B4_3613 -1.1 -1.7 hypothetical protein compare
Pf1N1B4_644 -1.1 -1.8 Cold shock protein CspC compare
Pf1N1B4_4476 -1.0 -3.0 Branched-chain amino acid aminotransferase (EC 2.6.1.42) compare
Pf1N1B4_1613 -1.0 -1.9 tRNA (cytidine(34)-2'-O)-methyltransferase (EC 2.1.1.207) compare
Pf1N1B4_1590 -1.0 -4.1 Histidine utilization repressor compare
Pf1N1B4_3290 -1.0 -1.9 Alternative cytochrome c oxidase polypeptide CoxP (EC 1.9.3.1) compare
Pf1N1B4_4494 -1.0 -3.0 hypothetical protein compare
Pf1N1B4_1570 -1.0 -2.6 Ribosomal RNA small subunit methyltransferase E (EC 2.1.1.-) compare
Pf1N1B4_2711 -1.0 -2.3 Phosphate starvation-inducible protein PhoH, predicted ATPase compare
Pf1N1B4_5997 -1.0 -2.4 Taurine dioxygenase (EC 1.14.11.17) compare
Pf1N1B4_2490 -1.0 -3.8 Biotin synthesis protein BioC compare
Pf1N1B4_795 -1.0 -2.6 hypothetical protein compare
Pf1N1B4_5311 -0.9 -1.6 hypothetical protein compare
Pf1N1B4_5383 -0.9 -4.6 hypothetical protein compare
Pf1N1B4_3328 -0.9 -1.8 Rhodanese-like domain protein compare
Pf1N1B4_4028 -0.9 -2.6 NADH-ubiquinone oxidoreductase chain N (EC 1.6.5.3) compare
Pf1N1B4_364 -0.9 -3.1 Rhodanese domain protein UPF0176 compare
Pf1N1B4_2163 -0.9 -1.5 hypothetical protein compare
Pf1N1B4_2739 -0.9 -1.5 acetyltransferase, GNAT family compare
Pf1N1B4_2225 -0.9 -6.2 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) compare
Pf1N1B4_275 -0.9 -1.6 Organic hydroperoxide resistance transcriptional regulator compare
Pf1N1B4_4518 -0.9 -1.4 Possible pyrimidine permease in reductive pathway compare
Pf1N1B4_2683 -0.9 -3.5 LrgA-associated membrane protein LrgB compare
Pf1N1B4_2860 -0.9 -3.9 FIG00954153: hypothetical protein compare
Pf1N1B4_3439 -0.8 -2.4 hypothetical protein compare
Pf1N1B4_5472 -0.8 -2.6 hypothetical protein compare
Pf1N1B4_2856 -0.8 -2.8 Poly(A) polymerase (EC 2.7.7.19) compare
Pf1N1B4_327 -0.8 -1.6 hypothetical protein compare
Pf1N1B4_3152 -0.8 -3.7 LysR family transcriptional regulator PA3398 compare
Pf1N1B4_749 -0.8 -1.7 hypothetical protein compare
Pf1N1B4_3849 -0.8 -2.7 Transcriptional regulator, GntR family compare
Pf1N1B4_1611 -0.8 -3.2 Nitrogen regulation protein NR(I) compare
Pf1N1B4_1870 -0.8 -1.9 Zinc ABC transporter, ATP-binding protein ZnuC compare
Pf1N1B4_3685 -0.8 -2.7 Succinyl-CoA ligase [ADP-forming] alpha chain (EC 6.2.1.5) compare
Pf1N1B4_6036 -0.8 -2.2 FIG00953132: hypothetical protein compare
Pf1N1B4_4969 -0.8 -1.5 FIG00956189: hypothetical protein compare
Pf1N1B4_2924 -0.8 -2.2 FIG00955589: hypothetical protein compare
Pf1N1B4_3002 -0.8 -1.5 hypothetical protein compare
Pf1N1B4_611 -0.8 -2.1 CoA transferase, CAIB/BAIF family compare
Pf1N1B4_718 -0.8 -3.7 outer membrane component of uptake system, probably for ferrous iron (from data) compare
Pf1N1B4_5382 -0.8 -2.2 hypothetical protein compare
Pf1N1B4_6035 -0.8 -2.4 D-ribose ABC transporter, substrate-binding component RbsB (from data) compare
Pf1N1B4_5899 -0.8 -1.8 FIG00954746: hypothetical protein compare
Pf1N1B4_2526 -0.8 -6.6 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf1N1B4_4477 -0.8 -2.1 Dihydrolipoamide dehydrogenase of branched-chain alpha-keto acid dehydrogenase (EC 1.8.1.4) compare
Pf1N1B4_2252 -0.8 -2.3 Organosulfonate utilization protein SsuF compare
Pf1N1B4_5699 -0.8 -1.6 ABC-type uncharacterized transport system, ATPase component compare
Pf1N1B4_5659 -0.8 -5.5 NfuA Fe-S protein maturation compare
Pf1N1B4_2005 -0.8 -1.1 ATP-dependent DNA helicase UvrD/PcrA compare
Pf1N1B4_7 -0.8 -2.5 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
Pf1N1B4_2958 -0.8 -2.0 Medium-chain-fatty-acid--CoA ligase (EC 6.2.1.-) compare
Pf1N1B4_4866 -0.8 -1.8 hypothetical protein compare
Pf1N1B4_3905 -0.8 -2.5 FIG00953423: hypothetical protein compare
Pf1N1B4_2209 -0.8 -4.8 Exopolyphosphatase (EC 3.6.1.11) compare
Pf1N1B4_5884 -0.8 -1.8 UDP-glucose dehydrogenase (EC 1.1.1.22) compare
Pf1N1B4_4027 -0.8 -1.6 hypothetical protein compare
Pf1N1B4_1159 -0.8 -2.0 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
Pf1N1B4_6038 -0.8 -2.8 FIG00953874: hypothetical protein compare
Pf1N1B4_5067 -0.8 -1.8 PUTATIVE TRANSFERASE PROTEIN( EC:2.- ) compare
Pf1N1B4_197 -0.8 -1.7 FIG139991: Putative thiamine pyrophosphate-requiring enzyme compare
Pf1N1B4_3528 -0.8 -3.5 Putative membrane protein compare
Pf1N1B4_3498 -0.8 -1.4 FIG00953240: hypothetical protein compare
Pf1N1B4_4295 -0.8 -2.0 FIG00954434: hypothetical protein compare
Pf1N1B4_2489 -0.8 -3.0 Biotin synthesis protein BioH compare
Pf1N1B4_5059 -0.8 -1.4 Transcriptional regulator, LysR family compare
Pf1N1B4_4887 -0.8 -2.0 Pirin compare
Pf1N1B4_4446 -0.8 -1.6 DNA topoisomerase III (EC 5.99.1.2) compare
Pf1N1B4_1872 -0.8 -4.0 Zinc ABC transporter, periplasmic-binding protein ZnuA compare
Pf1N1B4_1993 -0.8 -1.2 C4-type zinc finger protein, DksA/TraR family compare
Pf1N1B4_4473 -0.8 -1.9 Homoserine/homoserine lactone efflux protein compare
Pf1N1B4_5146 -0.7 -1.3 Chromosome initiation inhibitor compare
Pf1N1B4_6037 -0.7 -2.1 L-asparaginase (EC 3.5.1.1) compare
Pf1N1B4_133 -0.7 -1.8 Sigma-70 factor FpvI (ECF subfamily), controling pyoverdin biosynthesis compare
Pf1N1B4_717 -0.7 -3.9 Iron-regulated protein A precursor compare
Pf1N1B4_3722 -0.7 -1.9 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf1N1B4_5957 -0.7 -1.9 Arsenical resistance operon repressor compare
Pf1N1B4_366 -0.7 -4.1 FIG00954136: hypothetical protein compare
Pf1N1B4_5137 -0.7 -3.9 Carboxynorspermidine decarboxylase, putative (EC 4.1.1.-) compare
Pf1N1B4_13 -0.7 -2.0 SAM-dependent methyltransferase YafE (UbiE paralog) compare
Pf1N1B4_2983 -0.7 -1.7 hypothetical protein compare
Pf1N1B4_769 -0.7 -3.4 Aerobic glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) compare
Pf1N1B4_3709 -0.7 -2.0 Adenosylcobinamide-phosphate synthase (EC 6.3.1.10) compare
Pf1N1B4_2105 -0.7 -1.3 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf1N1B4_1569 -0.7 -5.3 Twin-arginine translocation protein TatC compare
Pf1N1B4_5284 -0.7 -1.3 hypothetical protein compare
Pf1N1B4_6028 -0.7 -2.7 FIG00954052: hypothetical protein compare
Pf1N1B4_3927 -0.7 -1.2 hypothetical protein compare
Pf1N1B4_2925 -0.7 -2.1 hypothetical protein compare
Pf1N1B4_2695 -0.7 -1.5 Rare lipoprotein A precursor compare
Pf1N1B4_1191 -0.7 -1.3 hypothetical protein compare
Pf1N1B4_3458 -0.7 -1.9 hypothetical protein compare
Pf1N1B4_74 -0.7 -1.5 hypothetical protein compare
Pf1N1B4_1052 -0.7 -1.2 FKBP-type peptidyl-prolyl cis-trans isomerase SlyD (EC 5.2.1.8) compare
Pf1N1B4_4931 -0.7 -1.3 Glutarate-semialdehyde dehydrogenase (EC 1.2.1.20); Succinate-semialdehyde dehydrogenase [NADP+] (EC 1.2.1.79) compare
Pf1N1B4_164 -0.7 -1.6 ADP-ribosylglycohydrolase family protein compare
Pf1N1B4_1348 -0.7 -1.6 Urease accessory protein UreD compare
Pf1N1B4_2706 -0.7 -1.7 FIG00954871: hypothetical protein compare
Pf1N1B4_1819 -0.7 -2.0 NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2) compare
Pf1N1B4_3241 -0.7 -1.4 hypothetical protein compare


Specific Phenotypes

For 4 genes in this experiment

For carbon source Sodium D,L-Lactate in Pseudomonas fluorescens FW300-N1B4

For carbon source Sodium D,L-Lactate across organisms