Experiment set1IT034 for Sinorhizobium meliloti 1021

Compare to:

Beta-Lactose carbon source

200 most important genes:

  gene name fitness t score description  
SMc01726 -8.8 -6.1 acetylglutamate kinase compare
SMc01843 -8.8 -6.1 5,10-methylenetetrahydrofolate reductase compare
SMc02766 -8.7 -10.4 tryptophan synthase subunit beta compare
SMc00235 -8.2 -5.7 anthranilate phosphoribosyltransferase compare
SMc02899 -8.2 -9.8 prephenate dehydratase compare
SMc00236 -8.1 -5.6 Indole-3-glycerol phosphate synthase compare
SMc02572 -8.1 -4.0 imidazole glycerol phosphate synthase subunit HisH compare
SMc00917 -8.0 -5.6 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
SMc02569 -8.0 -5.5 imidazole glycerol phosphate synthase subunit HisF compare
SMc01801 -7.8 -5.1 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) compare
SMc02767 -7.7 -10.6 N-(5'-phosphoribosyl)anthranilate isomerase compare
SMc04045 -7.7 -5.3 dihydroxy-acid dehydratase compare
SMc02717 -7.7 -7.5 2-isopropylmalate synthase compare
SMc01431 -7.6 -5.3 acetolactate synthase 3 catalytic subunit compare
SMc02725 -7.6 -10.4 anthranilate synthase compare
SMc00640 -7.6 -7.4 phosphoserine aminotransferase compare
SMc04405 -7.3 -10.0 3-isopropylmalate dehydrogenase compare
SMc01494 -7.2 -13.0 phosphoserine phosphatase compare
SMc02245 -7.2 -7.0 dihydroorotate dehydrogenase 2 compare
SMc03797 -7.1 -11.8 homoserine O-succinyltransferase compare
SMc00918 -6.9 -9.5 ATP phosphoribosyltransferase regulatory subunit compare
SMc01361 -6.9 -4.8 dihydroorotase compare
SMc04028 -6.9 -16.8 glutamate synthase compare
SMc00488 -6.9 -19.4 phosphoribosylformylglycinamidine synthase II compare
SMc00711 -6.9 -6.5 cyclohexadienyl dehydrogenase compare
SMc00614 -6.8 -8.1 phosphoribosylglycinamide formyltransferase compare
SMc00494 -6.8 -2.6 phosphoribosylformylglycinamidine synthase subunit PurS compare
SMc04002 -6.8 -7.6 phosphoribosylaminoimidazole carboxylase ATPase subunit compare
SMc02425 -6.8 -4.7 transcriptional regulator compare
SMc02765 -6.7 -12.0 tryptophan synthase subunit alpha compare
SMc00412 -6.7 -4.6 orotidine 5'-phosphate decarboxylase compare
SMa1635 -6.6 -2.5 hypothetical protein compare
SM_b21174 -6.6 -6.5 phosphate uptake ABC transporter permease compare
SMc02217 -6.6 -7.9 O-succinylhomoserine sulfhydrylase compare
SMc01881 -6.6 -4.5 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
SMc00554 -6.6 -7.8 amidophosphoribosyltransferase compare
SMc04026 -6.5 -11.4 glutamate synthase compare
SMc00293 -6.5 -14.6 homoserine dehydrogenase compare
SMc00495 -6.5 -5.4 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
SMc01004 -6.4 -9.3 phosphoribosyl-AMP cyclohydrolase compare
SMc03112 -6.4 -19.1 B12-dependent methionine synthase compare
SMc03895 -6.4 -19.7 pyruvate carboxylase compare
SM_b21655 -6.3 -18.3 Beta-galactosidase (EC 3.2.1.23) (from data) compare
SMc00993 -6.3 -10.6 phosphoribosylamine--glycine ligase compare
SMc03777 -6.3 -8.6 gamma-glutamyl phosphate reductase compare
SMc01360 -6.3 -4.3 aspartate carbamoyltransferase catalytic subunit compare
SMc03826 -6.2 -4.3 argininosuccinate synthase compare
SMc02137 -6.2 -4.8 ornithine carbamoyltransferase compare
SMc00493 -6.2 -8.4 phosphoribosylformylglycinamidine synthase I compare
SMc04088 -6.0 -9.1 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase compare
SMc00882 -5.9 -5.8 2-dehydro-3-deoxy-6-phosphogalactonate aldolase compare
SMc02755 -5.8 -5.6 S-adenosyl-L-homocysteine hydrolase compare
SMc02165 -5.5 -10.6 orotate phosphoribosyltransferase compare
SMc03823 -5.5 -12.4 isopropylmalate isomerase large subunit compare
SMc03979 -5.4 -3.7 glyceraldehyde-3-phosphate dehydrogenase compare
SMc00615 -5.3 -8.6 phosphoribosylaminoimidazole synthetase compare
SMc02166 -5.3 -11.4 dihydroorotase compare
SMc03763 -5.1 -3.5 cytosine-specific methyltransferase compare
SMc02570 -5.1 -5.0 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
SMc03776 -5.1 -4.9 gamma-glutamyl kinase compare
SMc02123 -5.0 -5.3 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
SMc01215 -4.9 -3.4 carbamoyl phosphate synthase large subunit compare
SMc01054 -4.9 -3.9 required for sulfate utilization, putative electron source for sulfite reductase CysI (from data) compare
SMc01569 -4.9 -2.5 carbamoyl phosphate synthase small subunit compare
SMc00092 -4.8 -13.2 phosphoadenosine phosphosulfate reductase compare
SM_b21175 -4.7 -6.7 phosphate uptake ABC transporter permease compare
SMc00131 -4.6 -16.7 transcriptional regulator compare
SMc04001 -4.6 -1.7 phosphoribosylaminoimidazole carboxylase catalytic subunit protein compare
SMc02138 -4.6 -6.5 acetylornithine transaminase compare
SMc03978 -4.5 -4.4 transketolase compare
SMc01770 -4.5 -2.0 serine hydroxymethyltransferase compare
SMc00815 -4.5 -3.7 inosine 5'-monophosphate dehydrogenase compare
SMc00017 -4.4 -2.3 homoserine kinase compare
SMc03795 -4.3 -2.3 isopropylmalate isomerase small subunit compare
SMc01880 -4.3 -5.1 pantoate--beta-alanine ligase compare
SMc02707 -4.2 -3.1 hypothetical protein compare
SMc00090 -4.2 -13.2 sulfate adenylyltransferase compare
SMc02124 -4.2 -13.2 nitrite reductase compare
SM_b21177 -4.1 -10.6 phosphate uptake ABC transporter ATP-binding protein compare
SMc00294 -4.0 -11.6 aminotransferase compare
SMc02307 -3.9 -10.8 histidinol dehydrogenase compare
SMc00876 -3.9 -9.4 ATP-binding MRP protein compare
SMc00091 -3.8 -13.6 sulfate adenylyltransferase compare
SMc00641 -3.7 -5.1 D-3-phosphoglycerate dehydrogenase compare
SMc01053 -3.6 -5.6 siroheme synthase compare
SM_b21652 -3.5 -7.4 ABC transporter for Lactose, periplasmic substrate-binding component (from data) conserved
SMc00295 -3.5 -1.6 hypothetical protein compare
SMc03229 -3.4 -2.5 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase compare
SMc04346 -3.3 -4.6 ketol-acid reductoisomerase compare
SM_b21653 -3.3 -9.1 ABC transporter for Lactose, permease component 1 (from data) conserved
SM_b21176 -3.3 -5.1 phosphate uptake ABC transporter substrate-binding protein precursor compare
SM_b21654 -3.2 -8.6 ABC transporter for Lactose, permease component 2 (from data) compare
SM_b20002 -3.2 -12.1 ABC transporter for Lactose, ATPase component (from data) conserved
SMc00982 -3.2 -9.6 dioxygenase compare
SMc03981 -2.9 -5.9 phosphoglycerate kinase compare
SMc02246 -2.8 -1.5 hypothetical protein compare
SMc00963 -2.7 -8.5 hypothetical protein compare
SMc00981 -2.6 -8.7 ferredoxin protein compare
SMc00881 -2.6 -12.1 2-dehydro-3-deoxygalactonokinase compare
SMc00414 -2.5 -11.6 hypothetical protein compare
SMc02172 -2.4 -12.8 transcriptional regulator compare
SMc02983 -2.4 -8.7 ornithine, DAP, or arginine decarboxylase compare
SMc04005 -2.4 -8.8 pyruvate kinase compare
SMc01430 -2.1 -8.7 acetolactate synthase 3 regulatory subunit compare
SMc00451 -1.9 -7.5 processing protease compare
SMc02141 -1.9 -4.4 phosphate transporter PhoU compare
SMc00321 -1.9 -9.0 tRNA pseudouridine synthase B compare
SMa0955 -1.8 -2.4 GntR family transcriptional regulator compare
SMc03070 -1.8 -9.3 glucose-6-phosphate 1-dehydrogenase compare
SMc04296 -1.8 -1.4 cell division protein FtsZ compare
SMc00334 -1.8 -3.0 cytidylate kinase compare
SMc01206 -1.7 -2.8 queuine tRNA-ribosyltransferase compare
SMc04224 -1.6 -1.4 hypothetical protein compare
SMc00427 -1.6 -4.3 peptide chain release factor RF-3 protein compare
SMc02050 -1.6 -4.6 trigger factor compare
SMc02407 -1.6 -6.4 hypothetical protein compare
SMc01124 -1.6 -5.0 PII uridylyl-transferase compare
SMc02850 -1.5 -3.9 DNA polymerase I compare
SM_b20387 -1.5 -2.1 transcriptional regulator compare
SMc02640 -1.4 -4.0 UDP-glucuronic acid epimerase compare
SMc02435 -1.4 -2.3 methyltransferase compare
SMc02227 -1.4 -5.4 fatty oxidation complex enoyl-COA hydratase/3-hydroxyacyl-COA dehydrogenase/3-hydroxybutyryl-COA epimerase compare
SMc00296 -1.3 -6.4 POLY3-hydroxybutyrate polymerase compare
SMa1095 -1.3 -1.2 hypothetical protein compare
SMc01147 -1.3 -3.4 coproporphyrinogen III oxidase compare
SMc00880 -1.3 -1.3 oxidoreductase compare
SMc01207 -1.3 -2.7 S-adenosylmethionine--tRNA ribosyltransferase-isomerase compare
SMc02724 -1.3 -3.0 hypothetical protein compare
SMc02753 -1.3 -1.8 PTS system transporter subunit IIA compare
SMc00838 -1.3 -3.9 hypothetical protein compare
SMc01187 -1.3 -3.0 rare lipoprotein A compare
SM_b20307 -1.2 -1.1 dihydroxyacetone kinase compare
SMc02434 -1.2 -3.3 hypothetical protein compare
SMc00349 -1.2 -5.8 GTP-binding protein LepA compare
SMc01578 -1.2 -7.2 aspartate aminotransferase compare
SMc03100 -1.2 -1.0 hypothetical protein compare
SMc04000 -1.1 -0.8 hypothetical protein compare
SMc02308 -1.1 -3.5 hypothetical protein compare
SMc02833 -1.1 -2.0 penicillin-insensitive murein endopeptidase compare
SMc02901 -1.1 -1.1 hypothetical protein compare
SMc01183 -1.1 -1.7 LexA repressor compare
SMc00709 -1.1 -3.4 hypothetical protein compare
SMa0789 -1.1 -3.0 GntR family transcriptional regulator compare
SMc00619 -1.1 -2.1 hypothetical protein compare
SMc03974 -1.1 -4.2 hypothetical protein compare
SMc02778 -1.1 -1.0 hydroxyacid aldolase compare
SMc01260 -1.0 -4.5 transcriptional regulator compare
SMa2020 -1.0 -4.7 Transcriptional regulator compare
SMc02574 -1.0 -2.0 imidazoleglycerol-phosphate dehydratase compare
SMa5031 -1.0 -2.3 hypothetical protein compare
SMc02363 -1.0 -2.5 cytochrome C-type biogenesis transmembrane protein compare
SMc01028 -1.0 -7.4 phosphopyruvate hydratase compare
SMc01495 -1.0 -4.1 transcriptional regulator compare
SMc00726 -1.0 -0.9 thiol:disulfide interchange redox-active center transmembrane protein compare
SMc01438 -1.0 -4.9 protease precursor signal peptide protein compare
SM_b21347 -1.0 -1.6 pectin degradation protein compare
SMc00302 -1.0 -2.5 hypothetical protein compare
SMc02102 -1.0 -3.2 hypothetical protein compare
SMc00579 -1.0 -2.7 dimethyladenosine transferase compare
SMa1924 -1.0 -0.9 hypothetical protein compare
SMc01364 -0.9 -1.0 DNA topoisomerase I compare
SMc01440 -0.9 -3.5 hydrolase serine protease transmembrane protein compare
SMc02084 -0.9 -1.1 biopolymer transport transmembrane protein compare
SMc02228 -0.9 -5.1 acetyl-CoA acetyltransferase compare
SM_b20148 -0.9 -3.4 transcriptional regulator compare
SMc02451 -0.9 -1.7 hypothetical protein compare
SM_b20005 -0.9 -2.5 glutathione S-transferase compare
SMc00856 -0.9 -1.2 hypothetical protein compare
SMc01164 -0.9 -5.2 hypothetical protein compare
SMc01119 -0.9 -1.7 hypothetical protein compare
SMc00605 -0.9 -2.1 hypothetical protein compare
SMc03063 -0.9 -6.7 ABC transporter for D-maltose/D-trehalose/sucrose, permease component 2 (AglG) (from data) compare
SMc01012 -0.9 -1.2 hypothetical protein compare
SMa0164 -0.9 -2.5 hypothetical protein compare
SMc03949 -0.9 -3.1 nitrogen regulatory protein compare
SMc04244 -0.9 -4.3 high-affinity zinc uptake system ATP-binding ABC transporter protein compare
SMc03184 -0.9 -1.4 PH adaptation potassium efflux system G transmembrane protein compare
SM_b21479 -0.8 -1.4 hypothetical protein compare
SMc03993 -0.8 -3.4 hypothetical protein compare
SMc02144 -0.8 -3.5 phosphate ABC transporter permease compare
SMc02641 -0.8 -3.4 UDP-glucose 6-dehydrogenase compare
SMc00914 -0.8 -2.6 oxidoreductase compare
SMc02838 -0.8 -4.7 phosphoglyceromutase compare
SMc01842 -0.8 -0.8 methyltransferase transcription regulator protein compare
SMc02147 -0.8 -4.4 phosphate regulon sensor histidine kinase transmembrane protein compare
SMc02384 -0.8 -4.4 glycosyltransferase transmembrane protein compare
SMc01441 -0.8 -4.2 membrane bound protease compare
SMc03065 -0.8 -5.0 ABC transporter for D-maltose/D-trehalose/sucrose, ATPase component (AglK) (from data) compare
SM_b22005 -0.8 -1.3 hypothetical protein compare
SMa1174 -0.8 -1.3 hypothetical protein compare
SMa0078 -0.8 -4.4 LacI family transcriptional regulator compare
SMc02121 -0.8 -1.4 ABC transporter for L-Glutamine, L-Histidine, and other L-amino acids, ATPase component (from data) compare
SMc02582 -0.8 -2.1 hypothetical protein compare
SMc03258 -0.8 -3.7 transcriptional regulator compare
SMc01144 -0.8 -2.2 ribonuclease PH compare
SM_b20075 -0.8 -1.6 hypothetical protein compare
SMc02115 -0.8 -0.7 hypothetical protein compare
SMc00466 -0.8 -3.2 hypothetical protein compare
SMc03061 -0.8 -5.1 ABC transporter for D-maltose/D-trehalose/sucrose, substrate-binding component (AglE) (from data) compare
SMc01845 -0.8 -0.7 transglycosylase transmembrane protein compare


Specific Phenotypes

For 8 genes in this experiment

For carbon source Beta-Lactose in Sinorhizobium meliloti 1021

For carbon source Beta-Lactose across organisms