Experiment set1IT033 for Pseudomonas fluorescens FW300-N1B4

Compare to:

Sodium L-Lactate carbon source

200 most important genes:

  gene name fitness t score description  
Pf1N1B4_6 -3.9 -4.7 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf1N1B4_2549 -3.6 -9.0 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf1N1B4_5666 -3.6 -3.4 Oxidoreductase probably involved in sulfite reduction compare
Pf1N1B4_1408 -3.4 -4.7 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf1N1B4_2880 -3.4 -11.2 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf1N1B4_2547 -3.4 -3.2 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
Pf1N1B4_1067 -3.3 -6.4 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf1N1B4_15 -3.2 -4.4 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf1N1B4_1534 -3.2 -16.8 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf1N1B4_3506 -3.2 -7.8 Cysteine synthase B (EC 2.5.1.47) compare
Pf1N1B4_1434 -3.1 -7.8 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf1N1B4_1624 -3.1 -8.7 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf1N1B4_12 -3.1 -7.2 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf1N1B4_5665 -3.1 -5.8 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf1N1B4_742 -3.1 -7.9 Argininosuccinate synthase (EC 6.3.4.5) compare
Pf1N1B4_2545 -3.1 -13.1 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
Pf1N1B4_1831 -3.0 -11.3 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf1N1B4_2338 -3.0 -7.7 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf1N1B4_2303 -3.0 -13.5 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf1N1B4_1830 -3.0 -8.5 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf1N1B4_2548 -3.0 -6.8 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf1N1B4_2010 -3.0 -5.3 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf1N1B4_350 -2.9 -6.7 Chorismate mutase I (EC 5.4.99.5) / Prephenate dehydratase (EC 4.2.1.51) compare
Pf1N1B4_1565 -2.9 -4.4 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf1N1B4_1533 -2.9 -8.3 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf1N1B4_2486 -2.9 -3.4 hypothetical protein compare
Pf1N1B4_1189 -2.9 -5.1 Predicted L-lactate dehydrogenase, hypothetical protein subunit YkgG compare
Pf1N1B4_2009 -2.9 -4.7 LysR family transcriptional regulator PA5437 compare
Pf1N1B4_2858 -2.8 -10.4 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf1N1B4_4065 -2.8 -7.9 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf1N1B4_1188 -2.8 -9.8 Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF conserved
Pf1N1B4_3812 -2.7 -8.1 Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) compare
Pf1N1B4_2384 -2.7 -9.7 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf1N1B4_3697 -2.7 -8.1 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf1N1B4_2272 -2.7 -4.7 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf1N1B4_2878 -2.6 -7.7 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf1N1B4_2879 -2.6 -7.5 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf1N1B4_1626 -2.6 -7.3 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf1N1B4_847 -2.6 -8.9 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf1N1B4_2337 -2.5 -5.1 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf1N1B4_1315 -2.5 -8.1 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) compare
Pf1N1B4_3917 -2.5 -4.9 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf1N1B4_2282 -2.5 -9.1 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf1N1B4_1186 -2.5 -9.0 L-lactate permease conserved
Pf1N1B4_2682 -2.4 -2.8 Antiholin-like protein LrgA compare
Pf1N1B4_2112 -2.4 -13.1 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
Pf1N1B4_2011 -2.4 -8.6 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf1N1B4_762 -2.4 -6.0 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf1N1B4_1627 -2.4 -4.9 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf1N1B4_1617 -2.3 -7.2 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (EC 5.4.2.1) compare
Pf1N1B4_1307 -2.3 -2.6 3-dehydroquinate dehydratase II (EC 4.2.1.10) compare
Pf1N1B4_1 -2.2 -2.0 Colicin V production protein compare
Pf1N1B4_1187 -2.1 -6.0 Predicted L-lactate dehydrogenase, Fe-S oxidoreductase subunit YkgE conserved
Pf1N1B4_3445 -2.0 -3.4 Succinylarginine dihydrolase (EC 3.5.3.23) compare
Pf1N1B4_1610 -1.9 -4.4 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
Pf1N1B4_1328 -1.9 -2.8 Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) compare
Pf1N1B4_2280 -1.8 -7.5 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf1N1B4_5448 -1.8 -2.3 hypothetical protein compare
Pf1N1B4_2377 -1.7 -6.0 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf1N1B4_3981 -1.7 -2.7 Predicted carboxypeptidase compare
Pf1N1B4_1906 -1.7 -3.4 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) compare
Pf1N1B4_1057 -1.6 -3.0 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf1N1B4_2859 -1.6 -10.8 Two-component sensor CbrA: intrcellular carbon:nitrogen balance compare
Pf1N1B4_2487 -1.6 -7.1 Biotin synthase (EC 2.8.1.6) compare
Pf1N1B4_365 -1.6 -4.7 Cell division protein BolA compare
Pf1N1B4_2856 -1.6 -3.9 Poly(A) polymerase (EC 2.7.7.19) compare
Pf1N1B4_3081 -1.6 -12.8 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
Pf1N1B4_2488 -1.6 -6.4 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf1N1B4_2105 -1.5 -2.3 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf1N1B4_652 -1.5 -7.1 Sensory box histidine kinase compare
Pf1N1B4_1625 -1.5 -3.1 FIG00956267: hypothetical protein compare
Pf1N1B4_2674 -1.5 -2.2 hypothetical protein compare
Pf1N1B4_2807 -1.5 -2.5 FKBP-type peptidyl-prolyl cis-trans isomerase SlpA (EC 5.2.1.8) compare
Pf1N1B4_2853 -1.5 -1.9 Pantoate--beta-alanine ligase (EC 6.3.2.1) compare
Pf1N1B4_2683 -1.4 -4.3 LrgA-associated membrane protein LrgB compare
Pf1N1B4_4393 -1.4 -2.1 Ferredoxin reductase compare
Pf1N1B4_3713 -1.4 -1.9 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) compare
Pf1N1B4_1566 -1.3 -5.3 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf1N1B4_5659 -1.3 -7.6 NfuA Fe-S protein maturation compare
Pf1N1B4_1614 -1.3 -2.5 Protein export cytoplasm chaperone protein (SecB, maintains protein to be exported in unfolded state) compare
Pf1N1B4_257 -1.3 -4.8 sensor histidine kinase/response regulator compare
Pf1N1B4_2189 -1.3 -2.2 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf1N1B4_3153 -1.3 -1.9 hypothetical protein compare
Pf1N1B4_2283 -1.3 -2.0 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf1N1B4_3356 -1.3 -1.9 Cyclic nucleotide-binding protein compare
Pf1N1B4_3751 -1.3 -1.2 FIG00953060: hypothetical protein compare
Pf1N1B4_4627 -1.3 -3.2 FIG00957600: hypothetical protein compare
Pf1N1B4_27 -1.3 -2.7 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf1N1B4_3768 -1.2 -2.2 Homoserine/homoserine lactone efflux protein compare
Pf1N1B4_4949 -1.2 -3.0 Formate dehydrogenase N gamma subunit (EC 1.2.1.2) compare
Pf1N1B4_1475 -1.2 -4.4 FIG00962376: hypothetical protein compare
Pf1N1B4_4103 -1.2 -2.3 Flagellar synthesis regulator FleN compare
Pf1N1B4_2209 -1.2 -6.1 Exopolyphosphatase (EC 3.6.1.11) compare
Pf1N1B4_578 -1.2 -2.1 enoyl-CoA hydratase, R-specific compare
Pf1N1B4_230 -1.2 -2.1 FIG00953472: hypothetical protein compare
Pf1N1B4_4717 -1.2 -1.7 Agmatinase (EC 3.5.3.11) compare
Pf1N1B4_4035 -1.2 -1.8 NADH-ubiquinone oxidoreductase chain G (EC 1.6.5.3) compare
Pf1N1B4_76 -1.2 -2.4 ATP binding protein compare
Pf1N1B4_32 -1.2 -2.9 Transcriptional regulator, TetR family compare
Pf1N1B4_3518 -1.2 -2.2 Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) compare
Pf1N1B4_2491 -1.2 -2.8 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf1N1B4_4563 -1.2 -1.8 Sulfate transporter compare
Pf1N1B4_2526 -1.1 -8.6 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf1N1B4_1837 -1.1 -1.4 Osmotically inducible protein C compare
Pf1N1B4_3241 -1.1 -2.0 hypothetical protein compare
Pf1N1B4_5552 -1.1 -2.3 hypothetical protein compare
Pf1N1B4_5880 -1.1 -1.6 AttH component of AttEFGH ABC transport system compare
Pf1N1B4_2004 -1.1 -1.6 putative membrane protein compare
Pf1N1B4_1819 -1.1 -2.3 NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2) compare
Pf1N1B4_5512 -1.1 -1.7 hypothetical protein compare
Pf1N1B4_716 -1.1 -2.8 Probable thiol oxidoreductase with 2 cytochrome c heme-binding sites compare
Pf1N1B4_197 -1.1 -1.6 FIG139991: Putative thiamine pyrophosphate-requiring enzyme compare
Pf1N1B4_3264 -1.1 -2.7 Methyltransferase (EC 2.1.1.-) compare
Pf1N1B4_3833 -1.1 -4.9 Major porin and structural outer membrane porin OprF compare
Pf1N1B4_2005 -1.1 -1.2 ATP-dependent DNA helicase UvrD/PcrA compare
Pf1N1B4_2489 -1.0 -3.5 Biotin synthesis protein BioH compare
Pf1N1B4_1069 -1.0 -3.9 YrbA protein compare
Pf1N1B4_2490 -1.0 -4.0 Biotin synthesis protein BioC compare
Pf1N1B4_2273 -1.0 -3.3 hypothetical protein compare
Pf1N1B4_3328 -1.0 -1.7 Rhodanese-like domain protein compare
Pf1N1B4_1653 -1.0 -4.1 Branched-chain amino acid transport protein AzlC compare
Pf1N1B4_5904 -1.0 -1.7 FIG00955320: hypothetical protein compare
Pf1N1B4_5342 -1.0 -1.5 hypothetical protein compare
Pf1N1B4_3836 -1.0 -2.0 Nitrite reductase [NAD(P)H] small subunit (EC 1.7.1.4) compare
Pf1N1B4_1180 -1.0 -1.8 Outer membrane lipoprotein SmpA, a component of the essential YaeT outer-membrane protein assembly complex compare
Pf1N1B4_1115 -1.0 -5.7 Dna binding response regulator PrrA (RegA) compare
Pf1N1B4_5747 -1.0 -2.2 Molybdopterin biosynthesis protein MoeA compare
Pf1N1B4_835 -1.0 -2.2 Trehalose-6-phosphate hydrolase (EC 3.2.1.93) compare
Pf1N1B4_3795 -1.0 -1.7 3-ketoacyl-CoA thiolase (EC 2.3.1.16) @ Acetyl-CoA acetyltransferase (EC 2.3.1.9) compare
Pf1N1B4_901 -1.0 -2.3 hypothetical protein compare
Pf1N1B4_1568 -1.0 -2.2 Twin-arginine translocation protein TatB compare
Pf1N1B4_718 -1.0 -3.8 outer membrane component of uptake system, probably for ferrous iron (from data) compare
Pf1N1B4_3152 -1.0 -3.7 LysR family transcriptional regulator PA3398 compare
Pf1N1B4_2684 -1.0 -1.4 Uncharacterized protein, similar to the N-terminal domain of Lon protease compare
Pf1N1B4_4602 -1.0 -1.8 Transcriptional regulators, LysR family compare
Pf1N1B4_1936 -1.0 -3.7 Chromosome (plasmid) partitioning protein ParA compare
Pf1N1B4_366 -1.0 -5.2 FIG00954136: hypothetical protein compare
Pf1N1B4_5618 -1.0 -2.5 Excinuclease ABC subunit C compare
Pf1N1B4_1558 -1.0 -2.1 Transcriptional regulator PhaD compare
Pf1N1B4_3990 -0.9 -2.7 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
Pf1N1B4_4317 -0.9 -1.7 DNA/RNA non-specific endonuclease compare
Pf1N1B4_2225 -0.9 -5.9 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) compare
Pf1N1B4_381 -0.9 -1.6 hypothetical protein compare
Pf1N1B4_5769 -0.9 -1.3 Heme d1 biosynthesis protein NirL compare
Pf1N1B4_1492 -0.9 -1.3 FIG00959437: hypothetical protein compare
Pf1N1B4_3420 -0.9 -2.7 Transcriptional regulator, AraC family compare
Pf1N1B4_3849 -0.9 -2.7 Transcriptional regulator, GntR family compare
Pf1N1B4_4857 -0.9 -3.2 Chemotaxis protein methyltransferase CheR (EC 2.1.1.80) compare
Pf1N1B4_5107 -0.9 -2.4 Putative collagenase compare
Pf1N1B4_629 -0.9 -1.6 Queuosine Biosynthesis QueE Radical SAM compare
Pf1N1B4_4166 -0.9 -1.8 Transcriptional regulator, LysR family compare
Pf1N1B4_1590 -0.9 -3.4 Histidine utilization repressor compare
Pf1N1B4_1054 -0.9 -1.8 Phosphate acetyltransferase (EC 2.3.1.8) compare
Pf1N1B4_5891 -0.9 -2.3 FIG00961753: hypothetical protein compare
Pf1N1B4_2984 -0.9 -2.9 VacJ-like lipoprotein precursor compare
Pf1N1B4_201 -0.9 -1.6 ABC transporter in pyoverdin gene cluster, ATP-binding component compare
Pf1N1B4_241 -0.9 -1.7 Thiol-disulfide isomerase and thioredoxins compare
Pf1N1B4_2757 -0.9 -2.2 DJ-1/YajL/PfpI superfamily, includes chaperone protein YajL (former ThiJ), parkinsonism-associated protein DJ-1, peptidases PfpI, Hsp31 compare
Pf1N1B4_4560 -0.9 -1.9 Transcriptional regulator, MerR family compare
Pf1N1B4_1234 -0.9 -2.5 Exodeoxyribonuclease V alpha chain (EC 3.1.11.5) compare
Pf1N1B4_150 -0.9 -2.3 SyrP-like protein compare
Pf1N1B4_3709 -0.9 -2.3 Adenosylcobinamide-phosphate synthase (EC 6.3.1.10) compare
Pf1N1B4_412 -0.9 -1.2 L-arabinose 1-dehydrogenase / D-galactose 1-dehydrogenase (EC 1.1.1.46; EC 1.1.1.48) (from data) compare
Pf1N1B4_2493 -0.9 -1.9 Acyl-CoA dehydrogenase (EC 1.3.8.7) compare
Pf1N1B4_349 -0.9 -2.4 Biosynthetic Aromatic amino acid aminotransferase beta (EC 2.6.1.57) compare
Pf1N1B4_4477 -0.8 -2.0 Dihydrolipoamide dehydrogenase of branched-chain alpha-keto acid dehydrogenase (EC 1.8.1.4) compare
Pf1N1B4_2870 -0.8 -1.5 Regulator of competence-specific genes compare
Pf1N1B4_2360 -0.8 -1.4 hypothetical protein compare
Pf1N1B4_4336 -0.8 -1.7 FMN-dependent NADH-azoreductase compare
Pf1N1B4_2688 -0.8 -2.4 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) compare
Pf1N1B4_5513 -0.8 -1.8 hypothetical protein compare
Pf1N1B4_198 -0.8 -1.7 FIG137877: Hypothetical protein in pyoverdin gene cluster compare
Pf1N1B4_3305 -0.8 -1.9 Urea carboxylase-related ABC transporter, permease protein compare
Pf1N1B4_2869 -0.8 -3.0 lipoprotein, putative compare
Pf1N1B4_2568 -0.8 -2.0 Translation elongation factor Tu compare
Pf1N1B4_722 -0.8 -1.2 SAM-dependent methyltransferases compare
Pf1N1B4_3935 -0.8 -2.2 Major facilitator family transporter compare
Pf1N1B4_2943 -0.8 -1.9 Tryptophan synthase beta chain like (EC 4.2.1.20) compare
Pf1N1B4_5383 -0.8 -4.8 hypothetical protein compare
Pf1N1B4_522 -0.8 -1.9 HlyD family secretion protein compare
Pf1N1B4_5261 -0.8 -1.0 hypothetical protein compare
Pf1N1B4_5348 -0.8 -1.8 hypothetical protein compare
Pf1N1B4_4285 -0.8 -2.0 Inositol transport system sugar-binding protein compare
Pf1N1B4_4612 -0.8 -1.6 FIG00954117: hypothetical protein compare
Pf1N1B4_1474 -0.8 -2.7 Glutamate-ammonia-ligase adenylyltransferase (EC 2.7.7.42) compare
Pf1N1B4_4247 -0.8 -2.1 D-aminopeptidase (EC 3.4.11.19) compare
Pf1N1B4_4414 -0.8 -2.1 Bll6261 protein compare
Pf1N1B4_4700 -0.8 -1.4 FIG00956898: hypothetical protein compare
Pf1N1B4_526 -0.8 -1.9 Undecaprenyl pyrophosphate synthase compare
Pf1N1B4_4569 -0.8 -1.5 DNA-3-methyladenine glycosylase II (EC 3.2.2.21) compare
Pf1N1B4_2981 -0.8 -2.4 hypothetical protein compare
Pf1N1B4_372 -0.8 -1.8 UDP-galactose-lipid carrier transferase (EC 2.-.-.-) compare
Pf1N1B4_4418 -0.8 -2.0 hypothetical protein compare
Pf1N1B4_3585 -0.8 -2.0 UDP-N-acetylglucosamine 4,6-dehydratase (EC 4.2.1.-) compare
Pf1N1B4_1668 -0.7 -2.7 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
Pf1N1B4_1116 -0.7 -4.9 Sensor histidine kinase PrrB (RegB) (EC 2.7.3.-) compare
Pf1N1B4_1535 -0.7 -1.7 hypothetical protein compare
Pf1N1B4_2224 -0.7 -1.4 FIG00953390: hypothetical protein compare
Pf1N1B4_5014 -0.7 -1.5 Glutathione reductase (EC 1.8.1.7) compare
Pf1N1B4_3443 -0.7 -1.8 Arginine N-succinyltransferase (EC 2.3.1.109) compare


Specific Phenotypes

For 3 genes in this experiment

For carbon source Sodium L-Lactate in Pseudomonas fluorescens FW300-N1B4

For carbon source Sodium L-Lactate across organisms