Experiment set1IT033 for Pseudomonas fluorescens FW300-N1B4

Compare to:

Sodium L-Lactate carbon source

200 most detrimental genes:

  gene name fitness t score description  
Pf1N1B4_4509 +1.2 2.8 Aldose 1-epimerase compare
Pf1N1B4_3501 +1.2 7.5 BarA sensory histidine kinase (= VarS = GacS) compare
Pf1N1B4_2060 +1.1 2.9 hypothetical protein compare
Pf1N1B4_507 +1.1 1.9 FIG00956448: hypothetical protein compare
Pf1N1B4_2210 +1.1 3.2 Glutamate transport ATP-binding protein compare
Pf1N1B4_218 +1.0 6.5 Periplasmic binding protein compare
Pf1N1B4_4358 +1.0 2.4 Acetyltransferase, GNAT family compare
Pf1N1B4_5340 +1.0 2.5 hypothetical protein compare
Pf1N1B4_4001 +1.0 2.3 Membrane fusion component of tripartite multidrug resistance system compare
Pf1N1B4_3582 +0.9 1.6 C-methyltransferase compare
Pf1N1B4_3141 +0.9 1.5 FIG00959768: hypothetical protein compare
Pf1N1B4_1782 +0.9 2.4 hypothetical protein compare
Pf1N1B4_188 +0.9 1.8 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf1N1B4_2851 +0.9 1.9 hypothetical protein compare
Pf1N1B4_688 +0.9 1.8 FIG00955483: hypothetical protein compare
Pf1N1B4_3991 +0.9 1.5 Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family compare
Pf1N1B4_5266 +0.8 2.1 hypothetical protein compare
Pf1N1B4_4818 +0.8 2.2 RNA polymerase sigma-70 factor, ECF subfamily compare
Pf1N1B4_5507 +0.8 2.0 hypothetical protein compare
Pf1N1B4_53 +0.8 2.6 hypothetical protein compare
Pf1N1B4_2145 +0.8 1.7 Translation initiation inhibitor compare
Pf1N1B4_1105 +0.8 1.8 4-carboxymuconolactone decarboxylase (EC 4.1.1.44) compare
Pf1N1B4_5073 +0.8 2.7 Hydroxypyruvate isomerase (EC 5.3.1.22) compare
Pf1N1B4_1967 +0.8 2.7 hypothetical protein compare
Pf1N1B4_1511 +0.8 1.3 FIG027190: Putative transmembrane protein compare
Pf1N1B4_1675 +0.8 1.9 Transcriptional regulator compare
Pf1N1B4_263 +0.8 2.2 Thiopurine S-methyltransferase (EC 2.1.1.67) compare
Pf1N1B4_761 +0.8 2.3 FIG00954879: hypothetical protein compare
Pf1N1B4_1461 +0.8 3.1 Protein fixF compare
Pf1N1B4_4331 +0.8 2.1 Transporter, LysE family compare
Pf1N1B4_899 +0.8 1.7 DNA polymerase III chi subunit (EC 2.7.7.7) compare
Pf1N1B4_5406 +0.7 2.6 hypothetical protein compare
Pf1N1B4_2178 +0.7 1.4 Regulator of nucleoside diphosphate kinase compare
Pf1N1B4_4951 +0.7 2.3 Tryptophan synthase beta chain like (EC 4.2.1.20) compare
Pf1N1B4_2227 +0.7 1.5 FIG019278: hypothetical protein compare
Pf1N1B4_5833 +0.7 2.0 Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A (EC 2.8.3.5) compare
Pf1N1B4_3892 +0.7 2.9 Multi antimicrobial extrusion protein (Na(+)/drug antiporter), MATE family of MDR efflux pumps compare
Pf1N1B4_1485 +0.7 2.7 FIG00963848: hypothetical protein compare
Pf1N1B4_1870 +0.7 1.6 Zinc ABC transporter, ATP-binding protein ZnuC compare
Pf1N1B4_4111 +0.7 2.1 Panthothenate synthetase compare
Pf1N1B4_5718 +0.7 1.9 Transcriptional regulator, Cro/CI family compare
Pf1N1B4_4842 +0.7 2.8 VgrG protein compare
Pf1N1B4_3115 +0.7 4.3 RNA polymerase sigma factor RpoS compare
Pf1N1B4_825 +0.7 1.5 tRNA (uridine-5-oxyacetic acid methyl ester) 34 synthase compare
Pf1N1B4_4869 +0.7 2.7 Isoquinoline 1-oxidoreductase beta subunit (EC 1.3.99.16) compare
Pf1N1B4_967 +0.7 1.5 hypothetical protein compare
Pf1N1B4_1754 +0.7 2.4 Putative stomatin/prohibitin-family membrane protease subunit aq_911 compare
Pf1N1B4_5870 +0.7 2.0 VgrG protein compare
Pf1N1B4_483 +0.7 1.5 Metal-dependent hydrolase related to alanyl-tRNA synthetase compare
Pf1N1B4_3975 +0.7 1.4 Transcriptional regulator, IclR family compare
Pf1N1B4_4118 +0.7 1.5 Cyn operon transcriptional activator compare
Pf1N1B4_2177 +0.7 1.1 FIG00953342: hypothetical protein compare
Pf1N1B4_823 +0.6 1.4 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf1N1B4_5055 +0.6 1.8 (R)-3-hydroxydecanoyl-ACP:CoA transacylase PhaG (3-hydroxyacyl-CoA-acyl carrier protein transferase) (EC 2.4.1.-) compare
Pf1N1B4_535 +0.6 2.4 FIG00953341: hypothetical protein compare
Pf1N1B4_2888 +0.6 2.0 FIG00961017: hypothetical protein compare
Pf1N1B4_3959 +0.6 2.0 2-aminoethylphosphonate:pyruvate aminotransferase (EC 2.6.1.37) compare
Pf1N1B4_1153 +0.6 1.9 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf1N1B4_4621 +0.6 2.3 L-arabonate dehydratase (EC 4.2.1.25) compare
Pf1N1B4_5274 +0.6 2.1 hypothetical protein compare
Pf1N1B4_3498 +0.6 1.7 FIG00953240: hypothetical protein compare
Pf1N1B4_2195 +0.6 2.0 Small-conductance mechanosensitive channel compare
Pf1N1B4_4108 +0.6 1.5 Hydrolase, alpha/beta fold family compare
Pf1N1B4_4558 +0.6 2.0 Outer membrane lipoprotein-sorting protein compare
Pf1N1B4_34 +0.6 1.3 Xanthine permease compare
Pf1N1B4_5860 +0.6 1.5 Two-component response regulator compare
Pf1N1B4_16 +0.6 2.0 Cys regulon transcriptional activator CysB compare
Pf1N1B4_5425 +0.6 1.3 DNA-binding protein HU-beta compare
Pf1N1B4_2390 +0.6 1.9 probable membrane protein NMA1176 compare
Pf1N1B4_2413 +0.6 2.0 Permeases of the major facilitator superfamily compare
Pf1N1B4_3483 +0.6 2.4 Transcriptional regulatory protein PhoP compare
Pf1N1B4_4246 +0.6 2.3 L-lactate permease compare
Pf1N1B4_1118 +0.6 1.7 Tryptophan synthase beta chain like (EC 4.2.1.20) compare
Pf1N1B4_3291 +0.6 1.8 Putative subunit of Alternative cytochrome c oxidase compare
Pf1N1B4_4636 +0.6 1.4 TPR domain protein in aerotolerance operon compare
Pf1N1B4_5907 +0.6 2.1 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases compare
Pf1N1B4_3613 +0.6 1.4 hypothetical protein compare
Pf1N1B4_676 +0.6 1.9 FIG00953991: hypothetical protein compare
Pf1N1B4_4250 +0.6 1.4 Methyltransferase (EC 2.1.1.-) compare
Pf1N1B4_182 +0.6 1.9 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases compare
Pf1N1B4_3538 +0.6 1.2 Transcriptional regulator, AraC family compare
Pf1N1B4_5284 +0.6 1.4 hypothetical protein compare
Pf1N1B4_855 +0.6 1.5 FIG021952: putative membrane protein compare
Pf1N1B4_5255 +0.6 1.4 hypothetical protein compare
Pf1N1B4_4721 +0.6 1.2 Nuclease inhibitor compare
Pf1N1B4_2359 +0.6 1.6 Chemotaxis signal transduction protein compare
Pf1N1B4_4937 +0.6 2.5 Two-component hybrid sensor and regulator compare
Pf1N1B4_4964 +0.6 1.7 Tricarboxylate transport protein TctB compare
Pf1N1B4_2635 +0.6 1.5 hypothetical protein compare
Pf1N1B4_4136 +0.6 1.6 hypothetical protein compare
Pf1N1B4_1695 +0.6 1.2 Cystine ABC transporter, ATP-binding protein compare
Pf1N1B4_1504 +0.6 1.3 Acyl carrier protein compare
Pf1N1B4_770 +0.6 1.6 hypothetical protein compare
Pf1N1B4_2640 +0.6 2.1 FIG003461: hypothetical protein compare
Pf1N1B4_3364 +0.6 1.3 Cyn operon transcriptional activator compare
Pf1N1B4_5463 +0.6 1.5 hypothetical protein compare
Pf1N1B4_4822 +0.6 1.5 Paraquat-inducible protein A compare
Pf1N1B4_5093 +0.6 1.6 Endo-beta-1,3-glucanase compare
Pf1N1B4_2421 +0.6 1.4 L-proline glycine betaine ABC transport system permease protein ProW (TC 3.A.1.12.1) compare
Pf1N1B4_4734 +0.6 1.8 Fap protein with C39 domain compare
Pf1N1B4_5353 +0.6 2.1 hypothetical protein compare
Pf1N1B4_339 +0.6 1.5 UDP-glucose 4-epimerase (EC 5.1.3.2) compare
Pf1N1B4_1958 +0.6 1.4 Tryptophan synthase beta chain like (EC 4.2.1.20) compare
Pf1N1B4_45 +0.6 3.0 Copper resistance protein B compare
Pf1N1B4_4132 +0.6 1.2 Mobile element protein compare
Pf1N1B4_2492 +0.5 2.2 FIG00954771: hypothetical protein compare
Pf1N1B4_5262 +0.5 2.1 hypothetical protein compare
Pf1N1B4_2106 +0.5 1.5 Hydrogen peroxide-inducible genes activator compare
Pf1N1B4_1008 +0.5 1.1 FIG006045: Sigma factor, ECF subfamily compare
Pf1N1B4_4505 +0.5 1.6 Coenzyme PQQ synthesis protein E compare
Pf1N1B4_5817 +0.5 1.6 Decarboxylase family protein compare
Pf1N1B4_2001 +0.5 2.0 cytosolic long-chain acyl-CoA thioester hydrolase family protein compare
Pf1N1B4_18 +0.5 2.4 16 kDa heat shock protein A compare
Pf1N1B4_3056 +0.5 1.9 Probable carboxyvinyl-carboxyphosphonate phosphorylmutase (EC 2.7.8.23) compare
Pf1N1B4_5432 +0.5 2.3 hypothetical protein compare
Pf1N1B4_4855 +0.5 1.6 Response regulator compare
Pf1N1B4_456 +0.5 2.2 FIG146278: Maf/YceF/YhdE family protein compare
Pf1N1B4_3546 +0.5 0.8 P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein compare
Pf1N1B4_3074 +0.5 1.3 HesA/MoeB/ThiF family protein related to EC-YgdL compare
Pf1N1B4_5854 +0.5 2.0 FIG00960144: hypothetical protein compare
Pf1N1B4_3485 +0.5 1.1 hypothetical protein compare
Pf1N1B4_4824 +0.5 1.2 Gamma-glutamyl-putrescine oxidase (EC1.4.3.-) compare
Pf1N1B4_3865 +0.5 1.4 Butyryl-CoA dehydrogenase (EC 1.3.99.2) compare
Pf1N1B4_1886 +0.5 2.2 FIG00956005: hypothetical protein compare
Pf1N1B4_3794 +0.5 1.2 hypothetical protein compare
Pf1N1B4_240 +0.5 1.2 Transcriptional regulators compare
Pf1N1B4_2284 +0.5 2.3 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
Pf1N1B4_2080 +0.5 1.9 hypothetical protein compare
Pf1N1B4_843 +0.5 2.0 Transcriptional regulator, LysR family compare
Pf1N1B4_3448 +0.5 1.5 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.78) compare
Pf1N1B4_4685 +0.5 1.9 4-alpha-glucanotransferase (amylomaltase) (EC 2.4.1.25) compare
Pf1N1B4_2075 +0.5 1.5 ABC-type antimicrobial peptide transport system, permease component compare
Pf1N1B4_1185 +0.5 2.5 Lactate-responsive regulator LldR in Enterobacteria, GntR family compare
Pf1N1B4_3211 +0.5 1.9 Putative signal peptide protein compare
Pf1N1B4_1718 +0.5 2.4 Transcriptional regulator, AraC family compare
Pf1N1B4_345 +0.5 1.1 Integration host factor beta subunit compare
Pf1N1B4_1336 +0.5 0.9 Putative multicopper oxidases compare
Pf1N1B4_5590 +0.5 1.4 Trans-feruloyl-CoA synthase (EC 6.2.1.34) compare
Pf1N1B4_2784 +0.5 1.4 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf1N1B4_6007 +0.5 1.1 Queuosine Biosynthesis QueC ATPase compare
Pf1N1B4_1194 +0.5 1.3 hypothetical protein compare
Pf1N1B4_5146 +0.5 1.3 Chromosome initiation inhibitor compare
Pf1N1B4_1703 +0.5 1.4 Methionine ABC transporter permease protein compare
Pf1N1B4_3020 +0.5 2.1 Single-stranded-DNA-specific exonuclease RecJ (EC 3.1.-.-) compare
Pf1N1B4_46 +0.5 1.8 Copper resistance protein C precursor compare
Pf1N1B4_3686 +0.5 2.9 Branched-chain amino acid transport system carrier protein compare
Pf1N1B4_1683 +0.5 1.1 Alpha-ketoglutarate-dependent taurine dioxygenase (EC 1.14.11.17) compare
Pf1N1B4_1595 +0.5 2.0 FIG027190: Putative transmembrane protein compare
Pf1N1B4_5704 +0.5 2.5 Long-chain fatty acid transport protein compare
Pf1N1B4_4849 +0.5 1.2 Various polyols ABC transporter, permease component 1 compare
Pf1N1B4_4402 +0.5 1.5 SoxH protein, homolog compare
Pf1N1B4_5680 +0.5 1.7 DNA polymerase-like protein PA0670 compare
Pf1N1B4_1135 +0.5 1.2 FIG00960055: hypothetical protein compare
Pf1N1B4_3968 +0.5 1.5 Spermidine/putrescine-binding periplasmic protein compare
Pf1N1B4_5249 +0.5 1.4 Outer membrane protein A precursor compare
Pf1N1B4_4008 +0.5 1.9 Various polyols ABC transporter, ATP-binding component compare
Pf1N1B4_122 +0.5 1.0 Inner membrane component of tripartite multidrug resistance system compare
Pf1N1B4_756 +0.5 1.0 hypothetical protein compare
Pf1N1B4_2711 +0.5 1.4 Phosphate starvation-inducible protein PhoH, predicted ATPase compare
Pf1N1B4_4516 +0.5 1.3 Pyridine nucleotide-disulphide oxidoreductase associated with reductive pyrimidine catabolism compare
Pf1N1B4_124 +0.5 1.1 Mechanosensitive ion channel compare
Pf1N1B4_1506 +0.5 2.2 FIGfam138462: Acyl-CoA synthetase, AMP-(fatty) acid ligase / (3R)-hydroxymyristoyl-[ACP] dehydratase (EC 4.2.1.-) compare
Pf1N1B4_1888 +0.5 2.0 Glutamate-aspartate carrier protein compare
Pf1N1B4_2464 +0.5 1.2 Ribosomal protein S6 glutaminyl transferase compare
Pf1N1B4_877 +0.5 2.4 Permeases of the major facilitator superfamily compare
Pf1N1B4_2026 +0.5 1.4 Transcriptional regulator compare
Pf1N1B4_2980 +0.5 1.4 Acetylornithine aminotransferase (EC 2.6.1.11) compare
Pf1N1B4_3767 +0.5 1.7 5-Hydroxyisourate Hydrolase (HIUase) (EC 3.5.2.17) compare
Pf1N1B4_3065 +0.5 1.6 FIG00954412: hypothetical protein compare
Pf1N1B4_1682 +0.5 2.3 Acetyltransferase, GNAT family (EC 2.3.1.-) compare
Pf1N1B4_5283 +0.5 1.1 hypothetical protein compare
Pf1N1B4_5346 +0.5 1.2 hypothetical protein compare
Pf1N1B4_5408 +0.5 1.5 hypothetical protein compare
Pf1N1B4_5777 +0.4 0.9 Nitrous oxide reductase maturation protein, outer-membrane lipoprotein NosL compare
Pf1N1B4_3853 +0.4 1.2 Xanthine dehydrogenase iron-sulfur subunit (EC 1.17.1.4) / Xanthine dehydrogenase, FAD binding subunit (EC 1.17.1.4) compare
Pf1N1B4_2417 +0.4 1.3 Betaine aldehyde dehydrogenase (EC 1.2.1.8) compare
Pf1N1B4_126 +0.4 1.0 Pirin compare
Pf1N1B4_4275 +0.4 1.4 Inosose dehydratase (EC 4.2.1.44) compare
Pf1N1B4_260 +0.4 1.4 Peptide methionine sulfoxide reductase MsrB (EC 1.8.4.12) compare
Pf1N1B4_1334 +0.4 1.0 FIG00955840: hypothetical protein compare
Pf1N1B4_5000 +0.4 1.5 D-glycerate transporter (predicted) compare
Pf1N1B4_5619 +0.4 2.0 BarA-associated response regulator UvrY (= GacA = SirA) compare
Pf1N1B4_5682 +0.4 1.1 SOS-response repressor and protease LexA (EC 3.4.21.88) compare
Pf1N1B4_68 +0.4 1.1 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) compare
Pf1N1B4_4777 +0.4 1.2 Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) compare
Pf1N1B4_3516 +0.4 3.4 TonB-dependent receptor; Outer membrane receptor for ferrienterochelin and colicins compare
Pf1N1B4_515 +0.4 1.4 DNA-binding response regulator GltR, controls specific porins for the entry of glucose compare
Pf1N1B4_708 +0.4 1.8 Chromosome initiation inhibitor compare
Pf1N1B4_1244 +0.4 1.9 Nucleoside ABC transporter, permease protein 1 compare
Pf1N1B4_5604 +0.4 1.4 Permeases of the major facilitator superfamily compare
Pf1N1B4_3814 +0.4 1.6 Para-aminobenzoate synthase, aminase component (EC 2.6.1.85) compare
Pf1N1B4_741 +0.4 1.5 DNA-binding response regulator, LuxR family compare
Pf1N1B4_2718 +0.4 2.0 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) compare
Pf1N1B4_4372 +0.4 1.0 Galactitol utilization operon repressor compare
Pf1N1B4_1003 +0.4 1.2 Tryptophan synthase beta chain like (EC 4.2.1.20) compare
Pf1N1B4_2232 +0.4 1.9 Ferric iron ABC transporter, iron-binding protein compare
Pf1N1B4_3036 +0.4 1.0 Chemotaxis signal transduction protein compare
Pf1N1B4_4726 +0.4 1.7 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) compare
Pf1N1B4_4168 +0.4 1.1 putative membrane protein compare
Pf1N1B4_5897 +0.4 1.6 FIG00963512: hypothetical protein compare


Specific Phenotypes

For 3 genes in this experiment

For carbon source Sodium L-Lactate in Pseudomonas fluorescens FW300-N1B4

For carbon source Sodium L-Lactate across organisms