Experiment set1IT028 for Pseudomonas fluorescens FW300-N2E2

Compare to:

D-Alanine carbon source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_5006 -7.2 -8.5 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_4596 -7.0 -9.6 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_4826 -6.5 -8.9 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_77 -6.4 -6.3 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_5175 -6.4 -15.5 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_71 -6.4 -7.6 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_4597 -6.2 -12.0 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_64 -6.2 -5.0 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_4390 -5.9 -13.3 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system conserved
Pf6N2E2_2753 -5.7 -3.9 HtrA protease/chaperone protein compare
Pf6N2E2_2277 -5.6 -3.8 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_2073 -5.6 -6.6 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_5176 -5.6 -13.4 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_5527 -5.6 -3.8 Cold shock protein CspC compare
Pf6N2E2_3782 -5.5 -6.6 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_3751 -5.5 -16.5 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_3783 -5.5 -7.5 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_3630 -5.4 -8.0 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_2218 -5.4 -3.7 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_3839 -5.3 -7.2 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_4047 -5.1 -7.8 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_2217 -5.1 -7.8 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_4825 -4.9 -11.0 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_4351 -4.9 -13.9 Predicted signal transduction protein compare
Pf6N2E2_3752 -4.8 -21.1 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_3940 -4.8 -12.4 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_2320 -4.7 -5.6 Heavy-metal-associated domain (N-terminus) and membrane-bounded cytochrome biogenesis cycZ-like domain, possible membrane copper tolerance protein compare
Pf6N2E2_3842 -4.5 -6.1 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_5177 -4.4 -9.9 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_4564 -4.3 -8.2 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_4391 -4.2 -9.8 D-amino acid dehydrogenase small subunit (EC 1.4.99.1) compare
Pf6N2E2_4048 -4.2 -9.0 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_3841 -4.2 -7.9 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_4759 -4.2 -15.3 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_4159 -4.2 -7.5 Cytochrome c4 compare
Pf6N2E2_2574 -4.1 -4.6 Flagellar synthesis regulator FleN compare
Pf6N2E2_2189 -4.0 -6.7 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
Pf6N2E2_3251 -4.0 -12.4 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_3300 -3.9 -5.9 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf6N2E2_66 -3.9 -8.6 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_302 -3.8 -6.7 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_2186 -3.8 -6.9 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
Pf6N2E2_2074 -3.8 -3.0 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_4279 -3.7 -14.1 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_3253 -3.7 -9.6 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_2318 -3.7 -9.0 Type cbb3 cytochrome oxidase biogenesis protein CcoI; Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_4453 -3.6 -17.6 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_5544 -3.6 -10.4 TPR repeat containing exported protein; Putative periplasmic protein contains a protein prenylyltransferase domain compare
Pf6N2E2_5156 -3.6 -4.9 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_3869 -3.6 -13.0 Branched-chain amino acid transport protein AzlC compare
Pf6N2E2_4638 -3.5 -5.8 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_3932 -3.5 -4.5 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_3610 -3.5 -3.8 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_5666 -3.5 -10.6 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_5337 -3.5 -6.5 Ubiquinol-cytochrome C reductase iron-sulfur subunit (EC 1.10.2.2) compare
Pf6N2E2_4278 -3.5 -11.7 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_50 -3.4 -8.6 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_3252 -3.4 -7.8 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_5338 -3.4 -12.1 Ubiquinol--cytochrome c reductase, cytochrome B subunit (EC 1.10.2.2) compare
Pf6N2E2_3271 -3.2 -4.0 Phosphocarrier protein, nitrogen regulation associated compare
Pf6N2E2_4277 -3.1 -9.8 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_3941 -3.1 -4.3 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf6N2E2_3942 -3.0 -10.2 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
Pf6N2E2_5459 -2.9 -11.9 D-serine/D-alanine/glycine transporter conserved
Pf6N2E2_5579 -2.9 -7.3 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_3661 -2.9 -6.7 hypothetical protein compare
Pf6N2E2_63 -2.9 -4.4 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_3825 -2.9 -5.6 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
Pf6N2E2_2310 -2.8 -12.3 Cytochrome c oxidase subunit CcoN (EC 1.9.3.1) compare
Pf6N2E2_1381 -2.8 -8.3 Aldehyde dehydrogenase (EC 1.2.1.3) compare
Pf6N2E2_5339 -2.7 -7.9 ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit compare
Pf6N2E2_4206 -2.7 -2.7 Chromosome (plasmid) partitioning protein ParB compare
Pf6N2E2_4372 -2.7 -7.5 FIG00460773: hypothetical protein compare
Pf6N2E2_4071 -2.7 -7.4 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_4187 -2.6 -4.9 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_5728 -2.6 -4.0 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_2311 -2.6 -10.9 Cytochrome c oxidase subunit CcoO (EC 1.9.3.1) compare
Pf6N2E2_2313 -2.6 -3.8 Cytochrome c oxidase subunit CcoP (EC 1.9.3.1) compare
Pf6N2E2_4761 -2.5 -12.0 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf6N2E2_1056 -2.5 -1.4 Quinone oxidoreductase (EC 1.6.5.5) compare
Pf6N2E2_4752 -2.5 -13.6 Malate synthase G (EC 2.3.3.9) compare
Pf6N2E2_4762 -2.5 -4.2 Biotin synthesis protein BioH compare
Pf6N2E2_3248 -2.5 -7.7 Probable transmembrane protein compare
Pf6N2E2_2527 -2.5 -6.0 Oxidoreductase, short chain dehydrogenase/reductase family compare
Pf6N2E2_5667 -2.4 -7.7 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_2317 -2.4 -4.7 Putative analog of CcoH, COG3198 compare
Pf6N2E2_5103 -2.4 -2.7 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
Pf6N2E2_1147 -2.4 -4.4 Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) compare
Pf6N2E2_2510 -2.3 -4.7 Lipid carrier : UDP-N-acetylgalactosaminyltransferase (EC 2.4.1.-) / Alpha-1,3-N-acetylgalactosamine transferase PglA (EC 2.4.1.-); Putative glycosyltransferase compare
Pf6N2E2_4584 -2.3 -2.9 Cell division transporter, ATP-binding protein FtsE (TC 3.A.5.1.1) compare
Pf6N2E2_2513 -2.3 -4.1 UDP-glucose dehydrogenase (EC 1.1.1.22) compare
Pf6N2E2_5157 -2.3 -9.2 Two-component sensor CbrA: intrcellular carbon:nitrogen balance compare
Pf6N2E2_3826 -2.3 -6.7 Nitrogen regulation protein NR(I) compare
Pf6N2E2_5403 -2.3 -11.0 ABC transporter for D-Alanine, permease component 2 (from data) compare
Pf6N2E2_3349 -2.2 -3.2 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_2514 -2.2 -5.9 regulator of length of O-antigen component of lipopolysaccharide chains compare
Pf6N2E2_4764 -2.2 -8.4 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_5001 -2.2 -3.8 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) compare
Pf6N2E2_3170 -2.2 -4.8 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_3062 -2.1 -4.6 Membrane-associated zinc metalloprotease compare
Pf6N2E2_2465 -2.0 -6.0 Cys regulon transcriptional activator CysB compare
Pf6N2E2_5405 -2.0 -6.3 ABC transporter for D-Alanine, ATPase component (from data) compare
Pf6N2E2_4987 -2.0 -1.8 MaoC-like domain protein compare
Pf6N2E2_2473 -2.0 -2.1 Major outer membrane lipoprotein I compare
Pf6N2E2_248 -2.0 -8.4 hypothetical protein compare
Pf6N2E2_5158 -2.0 -4.0 FIG00954153: hypothetical protein compare
Pf6N2E2_4631 -2.0 -7.3 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf6N2E2_3039 -1.9 -7.7 Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) compare
Pf6N2E2_5014 -1.9 -1.9 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_3885 -1.9 -3.0 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
Pf6N2E2_4763 -1.9 -9.7 Biotin synthesis protein BioC compare
Pf6N2E2_5242 -1.9 -2.7 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_5402 -1.8 -9.8 ABC transporter for D-Alanine, periplasmic substrate-binding component (from data) compare
Pf6N2E2_4097 -1.8 -10.9 FIG00953365: hypothetical protein compare
Pf6N2E2_5404 -1.8 -7.9 ABC transporter for D-Alanine, permease component 1 (from data) compare
Pf6N2E2_4009 -1.8 -8.9 GGDEF domain protein compare
Pf6N2E2_3786 -1.8 -3.3 Twin-arginine translocation protein TatC compare
Pf6N2E2_5258 -1.8 -7.7 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_3984 -1.8 -9.5 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_3461 -1.8 -2.5 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_510 -1.7 -9.9 Predicted transcriptional regulator of the myo-inositol catabolic operon compare
Pf6N2E2_5573 -1.7 -3.7 Glycerol-3-phosphate regulon repressor, DeoR family compare
Pf6N2E2_1932 -1.7 -5.1 Transcriptional regulator, IclR family compare
Pf6N2E2_4205 -1.7 -4.0 Chromosome (plasmid) partitioning protein ParA compare
Pf6N2E2_2309 -1.7 -2.2 hypothetical protein compare
Pf6N2E2_2340 -1.7 -4.2 Transcriptional regulator, GntR family compare
Pf6N2E2_3655 -1.6 -10.2 Hypothetical protein FIG015671 in large core OS assembly cluster compare
Pf6N2E2_3656 -1.6 -5.1 Probable transcription regulator Mig-14 compare
Pf6N2E2_5430 -1.6 -8.4 Transglycosylase, Slt family compare
Pf6N2E2_2022 -1.6 -7.6 BarA-associated response regulator UvrY (= GacA = SirA) compare
Pf6N2E2_4204 -1.6 -1.4 rRNA small subunit 7-methylguanosine (m7G) methyltransferase GidB compare
Pf6N2E2_3611 -1.6 -1.5 HflC protein compare
Pf6N2E2_5331 -1.6 -6.3 ATPase, AFG1 family compare
Pf6N2E2_2258 -1.5 -8.3 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_4451 -1.5 -5.1 FIG139438: lipoprotein B compare
Pf6N2E2_5257 -1.5 -8.0 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_6140 -1.5 -1.4 Large Subunit Ribosomal RNA; lsuRNA; LSU rRNA compare
Pf6N2E2_4803 -1.4 -2.1 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_2526 -1.4 -5.9 Similar to phosphoglycolate phosphatase, clustered with ubiquinone biosynthesis SAM-dependent O-methyltransferase compare
Pf6N2E2_3868 -1.4 -5.7 Transcriptional regulator, LysR family compare
Pf6N2E2_3834 -1.4 -5.9 Lipoprotein NlpD compare
Pf6N2E2_3060 -1.4 -2.9 Outer membrane protein H precursor compare
Pf6N2E2_51 -1.4 -4.8 hypothetical protein compare
Pf6N2E2_4059 -1.4 -1.4 DNA-binding protein HU-alpha compare
Pf6N2E2_5720 -1.4 -10.0 BarA sensory histidine kinase (= VarS = GacS) compare
Pf6N2E2_3379 -1.3 -8.6 Lactate-responsive regulator LldR in Enterobacteria, GntR family compare
Pf6N2E2_2794 -1.3 -2.3 putative membrane protein compare
Pf6N2E2_2201 -1.3 -4.7 Transmembrane regulator protein PrtR compare
Pf6N2E2_5950 -1.3 -4.3 Phosphate:acyl-ACP acyltransferase PlsX compare
Pf6N2E2_2316 -1.3 -8.0 Type cbb3 cytochrome oxidase biogenesis protein CcoG, involved in Cu oxidation compare
Pf6N2E2_75 -1.3 -4.7 Colicin V production protein compare
Pf6N2E2_5219 -1.3 -7.3 FIG140336: TPR domain protein compare
Pf6N2E2_5679 -1.2 -4.2 hypothetical protein compare
Pf6N2E2_3899 -1.2 -7.2 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) compare
Pf6N2E2_5401 -1.2 -6.9 phospholipase/carboxylesterase family protein compare
Pf6N2E2_5553 -1.2 -6.0 Quinolinate synthetase (EC 2.5.1.72) compare
Pf6N2E2_5190 -1.2 -8.7 Carbonic anhydrase (EC 4.2.1.1) compare
Pf6N2E2_1396 -1.1 -2.7 ABC transporter, ATP-binding protein compare
Pf6N2E2_5676 -1.1 -3.3 Aspartokinase (EC 2.7.2.4) compare
Pf6N2E2_4585 -1.1 -7.2 Cell division protein FtsX compare
Pf6N2E2_5536 -1.1 -1.3 Holliday junction DNA helicase RuvA compare
Pf6N2E2_2286 -1.1 -2.9 FIG00953287: hypothetical protein compare
Pf6N2E2_5160 -1.1 -1.8 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_3072 -1.1 -7.3 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
Pf6N2E2_3516 -1.1 -2.4 Probable transmembrane protein compare
Pf6N2E2_4413 -1.1 -2.6 FIG004064: hypothetical protein compare
Pf6N2E2_4810 -1.1 -5.2 Glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) compare
Pf6N2E2_2926 -1.1 -5.2 ABC transporter for L-leucine/L-isoleucine/L-phenylalanine/D-alanine, ATPase component 2 LivF (from data) conserved
Pf6N2E2_3835 -1.1 -3.6 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf6N2E2_4160 -1.1 -1.4 Cytochrome c5 compare
Pf6N2E2_3659 -1.1 -3.8 Protein fixF compare
Pf6N2E2_652 -1.0 -3.0 General secretion pathway protein E compare
Pf6N2E2_3933 -1.0 -6.0 D-2-hydroxyglutarate dehydrogenase compare
Pf6N2E2_1081 -1.0 -1.6 probable membrane protein YPO3302 compare
Pf6N2E2_4417 -1.0 -3.1 Protein of unknown function DUF484 compare
Pf6N2E2_3134 -1.0 -1.1 hypothetical protein compare
Pf6N2E2_1981 -1.0 -2.7 FIG051360: Periplasmic protein TonB, links inner and outer membranes compare
Pf6N2E2_3569 -1.0 -1.7 hypothetical protein compare
Pf6N2E2_5155 -1.0 -2.6 Poly(A) polymerase (EC 2.7.7.19) compare
Pf6N2E2_2869 -1.0 -1.6 Peptide deformylase (EC 3.5.1.88) compare
Pf6N2E2_3658 -1.0 -5.3 Lipid A core - O-antigen ligase and related enzymes compare
Pf6N2E2_3283 -1.0 -5.2 Cytoplasmic axial filament protein CafA and Ribonuclease G (EC 3.1.4.-) compare
Pf6N2E2_3040 -1.0 -4.5 5-nucleotidase SurE (EC 3.1.3.5) compare
Pf6N2E2_3672 -1.0 -5.7 Glutamate-ammonia-ligase adenylyltransferase (EC 2.7.7.42) compare
Pf6N2E2_3807 -1.0 -3.2 Histidine utilization repressor compare
Pf6N2E2_3346 -1.0 -3.6 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf6N2E2_2886 -1.0 -7.9 Phosphogluconate repressor HexR, RpiR family compare
Pf6N2E2_3833 -1.0 -4.4 hypothetical protein compare
Pf6N2E2_2389 -1.0 -6.8 Phosphoenolpyruvate synthase (EC 2.7.9.2) conserved
Pf6N2E2_4579 -1.0 -1.9 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
Pf6N2E2_5665 -1.0 -3.8 Succinylornithine transaminase (EC 2.6.1.81) compare
Pf6N2E2_4365 -0.9 -4.8 Ribonuclease PH (EC 2.7.7.56) compare
Pf6N2E2_2219 -0.9 -1.9 Cell division trigger factor (EC 5.2.1.8) compare
Pf6N2E2_2552 -0.9 -3.5 Cytochrome c heme lyase subunit CcmH compare
Pf6N2E2_3338 -0.9 -2.0 1-phosphofructokinase (EC 2.7.1.56) compare
Pf6N2E2_2391 -0.9 -6.1 FIG137360: hypothetical protein compare
Pf6N2E2_5793 -0.9 -5.2 Aspartyl aminopeptidase compare
Pf6N2E2_5328 -0.9 -4.1 FIG00958649: hypothetical protein compare
Pf6N2E2_4418 -0.9 -0.8 Diaminopimelate epimerase (EC 5.1.1.7) compare
Pf6N2E2_4317 -0.9 -2.9 FIG00964469: hypothetical protein compare


Specific Phenotypes

For 8 genes in this experiment

For carbon source D-Alanine in Pseudomonas fluorescens FW300-N2E2

For carbon source D-Alanine across organisms