Experiment set1IT028 for Pseudomonas fluorescens FW300-N2E2

Compare to:

D-Alanine carbon source

200 most detrimental genes:

  gene name fitness t score description  
Pf6N2E2_4394 +2.5 18.0 Putrescine utilization regulator compare
Pf6N2E2_482 +2.3 4.4 Transcriptional regulator BkdR of isoleucine and valine catabolism operon compare
Pf6N2E2_3037 +1.5 11.7 RNA polymerase sigma factor RpoS compare
Pf6N2E2_4414 +1.4 5.9 FIG00953808: hypothetical protein compare
Pf6N2E2_4148 +1.4 10.5 Glutamate-aspartate carrier protein compare
Pf6N2E2_923 +1.3 4.6 Haloacid dehalogenase, type II (EC 3.8.1.2) compare
Pf6N2E2_3981 +1.3 11.6 T1SS secreted agglutinin RTX compare
Pf6N2E2_3978 +1.2 10.4 Type I secretion system, membrane fusion protein LapC compare
Pf6N2E2_3979 +1.1 9.0 Type I secretion system ATPase, LssB family LapB compare
Pf6N2E2_4084 +1.1 6.9 Transcriptional regulator compare
Pf6N2E2_5084 +1.1 8.2 Glutathione-regulated potassium-efflux system ATP-binding protein compare
Pf6N2E2_4077 +1.0 2.6 cytosolic long-chain acyl-CoA thioester hydrolase family protein compare
Pf6N2E2_4369 +1.0 2.3 Exodeoxyribonuclease III (EC 3.1.11.2) compare
Pf6N2E2_919 +1.0 2.7 FIG00954373: hypothetical protein compare
Pf6N2E2_4743 +1.0 1.6 hypothetical protein compare
Pf6N2E2_5133 +0.9 3.5 FIG00953980: hypothetical protein compare
Pf6N2E2_3737 +0.8 1.6 General secretion pathway protein M compare
Pf6N2E2_3033 +0.8 1.9 hypothetical protein compare
Pf6N2E2_3539 +0.8 2.6 FIG00955840: hypothetical protein compare
Pf6N2E2_2296 +0.8 1.9 FIG00954767: hypothetical protein compare
Pf6N2E2_1896 +0.8 1.7 hypothetical protein compare
Pf6N2E2_4773 +0.8 1.3 Coenzyme PQQ synthesis protein D compare
Pf6N2E2_5757 +0.8 2.9 hypothetical protein compare
Pf6N2E2_2578 +0.8 1.9 Flagellar biosynthesis protein FliR compare
Pf6N2E2_924 +0.8 2.2 Transcriptional regulator XdhR, TetR family compare
Pf6N2E2_649 +0.8 2.9 General secretion pathway protein L compare
Pf6N2E2_5646 +0.8 1.8 PROBABLE MEMBRANE PROTEIN compare
Pf6N2E2_2708 +0.8 4.6 Lactam utilization protein LamB compare
Pf6N2E2_4813 +0.7 6.2 Probable two-component sensor, near polyamine transporter compare
Pf6N2E2_2284 +0.7 1.9 Cell division inhibitor-related protein compare
Pf6N2E2_4098 +0.7 5.8 Cytochrome c oxidase polypeptide II (EC 1.9.3.1) compare
Pf6N2E2_2273 +0.7 4.1 Glycerophosphoryl diester phosphodiesterase (EC 3.1.4.46) compare
Pf6N2E2_1032 +0.7 1.2 Alkanesulfonates ABC transporter ATP-binding protein / Sulfonate ABC transporter, ATP-binding subunit SsuB compare
Pf6N2E2_2282 +0.7 3.2 Predicted transcriptional regulator for fatty acid degradation FadQ, TetR family compare
Pf6N2E2_2597 +0.7 5.3 Flagellar regulatory protein FleQ compare
Pf6N2E2_2481 +0.7 4.2 Membrane protein, distant similarity to thiosulphate:quinone oxidoreductase DoxD compare
Pf6N2E2_2788 +0.7 1.5 Transcriptional regulator, AsnC family compare
Pf6N2E2_6087 +0.7 2.6 Short-chain dehydrogenase/reductase SDR compare
Pf6N2E2_3980 +0.7 5.5 Type I secretion system, outer membrane component LapE compare
Pf6N2E2_479 +0.7 3.1 Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase (EC 2.3.1.168) (from data) compare
Pf6N2E2_5712 +0.7 3.2 DNA-3-methyladenine glycosylase (EC 3.2.2.20) compare
Pf6N2E2_827 +0.7 1.8 probable dioxygenase compare
Pf6N2E2_4555 +0.7 4.6 Lysophospholipase (EC 3.1.1.5) compare
Pf6N2E2_1305 +0.7 2.1 Homoprotocatechuate degradative operon repressor compare
Pf6N2E2_2124 +0.7 1.6 Mg(2+) transport ATPase protein C compare
Pf6N2E2_2593 +0.7 3.8 Flagellar M-ring protein FliF compare
Pf6N2E2_1774 +0.7 1.3 DNA-binding response regulator, LuxR family, near polyamine transporter compare
Pf6N2E2_3151 +0.7 2.9 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_3875 +0.7 1.5 FIG00953324: hypothetical protein compare
Pf6N2E2_2594 +0.7 4.5 Flagellar hook-basal body complex protein FliE compare
Pf6N2E2_476 +0.7 2.3 Permease of the drug/metabolite transporter (DMT) superfamily compare
Pf6N2E2_1089 +0.7 1.1 Delta 1-piperideine-2-carboxylate reductase (EC 1.5.1.21) / Delta 1-pyrroline-2-carboxylate reductase (EC 1.5.1.1) compare
Pf6N2E2_1424 +0.6 1.2 transcriptional regulator, TetR family compare
Pf6N2E2_3713 +0.6 1.6 Acyl carrier protein compare
Pf6N2E2_1441 +0.6 2.3 Uncharacterized oxidoreductase ydgJ (EC 1.-.-.-) compare
Pf6N2E2_4415 +0.6 1.3 Putative FMN hydrolase (EC 3.1.3.-); 5-Amino-6-(5'-phosphoribitylamino)uracil phosphatase compare
Pf6N2E2_2706 +0.6 2.8 Allophanate hydrolase 2 subunit 2 (EC 3.5.1.54) compare
Pf6N2E2_3607 +0.6 4.2 3'-to-5' exoribonuclease RNase R compare
Pf6N2E2_2835 +0.6 1.1 Beta-ketoadipyl CoA thiolase (EC 2.3.1.-) compare
Pf6N2E2_2292 +0.6 2.5 Universal stress protein family COG0589 compare
Pf6N2E2_2447 +0.6 3.5 Probable protease htpX homolog (EC 3.4.24.-) compare
Pf6N2E2_5312 +0.6 1.6 FIG00964214: hypothetical protein compare
Pf6N2E2_2402 +0.6 1.6 hypothetical protein compare
Pf6N2E2_449 +0.6 2.1 Lactoylglutathione lyase (EC 4.4.1.5) compare
Pf6N2E2_3004 +0.6 1.3 Prophage baseplate assembly protein V compare
Pf6N2E2_4624 +0.6 1.0 Phosphoribosyl-dephospho-CoA transferase (EC 2.7.7.-) compare
Pf6N2E2_4534 +0.6 1.6 hypothetical protein compare
Pf6N2E2_4104 +0.6 4.3 Probable transmembrane protein compare
Pf6N2E2_2590 +0.6 4.8 Flagellum-specific ATP synthase FliI compare
Pf6N2E2_4367 +0.6 1.4 hypothetical protein compare
Pf6N2E2_4099 +0.6 5.4 Cytochrome c oxidase polypeptide I (EC 1.9.3.1) compare
Pf6N2E2_1975 +0.6 2.1 Integrase regulator R compare
Pf6N2E2_3685 +0.6 4.7 Transcriptional repressor of PutA and PutP / Proline dehydrogenase (EC 1.5.99.8) (Proline oxidase) / Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) compare
Pf6N2E2_2827 +0.6 1.2 hypothetical protein compare
Pf6N2E2_500 +0.6 1.3 Beta-ureidopropionase (EC 3.5.1.6) compare
Pf6N2E2_5178 +0.6 0.9 CDP-diacylglycerol--serine O-phosphatidyltransferase (EC 2.7.8.8) compare
Pf6N2E2_4105 +0.6 3.1 Heme A synthase, cytochrome oxidase biogenesis protein Cox15-CtaA compare
Pf6N2E2_2503 +0.6 0.7 Glycosyl transferase, group 1 family protein compare
Pf6N2E2_3908 +0.6 3.8 Glutamate--cysteine ligase (EC 6.3.2.2) compare
Pf6N2E2_2278 +0.6 4.8 Transcription-repair coupling factor compare
Pf6N2E2_1886 +0.6 1.1 hypothetical protein compare
Pf6N2E2_4101 +0.6 4.7 Cytochrome c oxidase polypeptide III (EC 1.9.3.1) compare
Pf6N2E2_2300 +0.6 2.7 LSU rRNA 2'-O-methyl-C2498 methyltransferase RlmM compare
Pf6N2E2_5460 +0.6 2.2 Phage protein compare
Pf6N2E2_2018 +0.6 1.2 hypothetical protein compare
Pf6N2E2_414 +0.6 2.1 Chemotaxis protein CheD compare
Pf6N2E2_1431 +0.6 2.2 Branched-chain amino acid transport system permease protein LivM (TC 3.A.1.4.1) compare
Pf6N2E2_1596 +0.6 1.3 Periplasmic nitrate reductase component NapD compare
Pf6N2E2_4984 +0.6 1.6 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_1248 +0.6 1.7 MutT/nudix family protein compare
Pf6N2E2_3740 +0.5 2.3 General secretion pathway protein J compare
Pf6N2E2_58 +0.5 1.2 tRNA-dihydrouridine synthase C (EC 1.-.-.-) compare
Pf6N2E2_1983 +0.5 1.2 hypothetical protein compare
Pf6N2E2_1588 +0.5 2.6 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) compare
Pf6N2E2_2477 +0.5 1.3 ABC transporter ATP-binding protein YvcR compare
Pf6N2E2_4721 +0.5 1.6 Sarcosine oxidase gamma subunit (EC 1.5.3.1) compare
Pf6N2E2_84 +0.5 1.2 hypothetical protein compare
Pf6N2E2_2267 +0.5 2.0 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) compare
Pf6N2E2_5240 +0.5 3.8 FIG00953775: hypothetical protein compare
Pf6N2E2_4612 +0.5 3.1 Glutathione synthetase (EC 6.3.2.3) compare
Pf6N2E2_5842 +0.5 1.9 Transcriptional regulator, TetR family compare
Pf6N2E2_5865 +0.5 4.0 Chaperone protein HtpG compare
Pf6N2E2_2576 +0.5 4.5 Flagellar biosynthesis protein FlhA compare
Pf6N2E2_3975 +0.5 2.4 Taurine transport ATP-binding protein TauB compare
Pf6N2E2_114 +0.5 1.2 Polysaccharide biosynthesis protein compare
Pf6N2E2_6075 +0.5 2.3 Chromosome segregation ATPases compare
Pf6N2E2_2563 +0.5 4.0 FIG00953562: hypothetical protein compare
Pf6N2E2_605 +0.5 2.1 FIG002465: BNR repeat protein compare
Pf6N2E2_5694 +0.5 3.1 Flagellar basal-body rod protein FlgB compare
Pf6N2E2_2591 +0.5 3.2 Flagellar assembly protein FliH compare
Pf6N2E2_737 +0.5 1.1 Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4) compare
Pf6N2E2_2583 +0.5 3.2 Flagellar motor switch protein FliM compare
Pf6N2E2_1701 +0.5 2.0 ABC transporter ATP-binding protein compare
Pf6N2E2_5391 +0.5 3.8 Predicted ATPase related to phosphate starvation-inducible protein PhoH compare
Pf6N2E2_4014 +0.5 3.8 Succinate-semialdehyde dehydrogenase [NAD(P)+] (EC 1.2.1.16) compare
Pf6N2E2_4979 +0.5 3.3 Aldehyde dehydrogenase (EC 1.2.1.3) compare
Pf6N2E2_5556 +0.5 2.6 Aminomethyltransferase (EC 2.1.2.10) (from data) compare
Pf6N2E2_2103 +0.5 1.8 hypothetical protein compare
Pf6N2E2_2580 +0.5 2.4 Flagellar biosynthesis protein FliP compare
Pf6N2E2_1215 +0.5 1.9 probable membrane protein YPO2362 compare
Pf6N2E2_2584 +0.5 3.2 Flagellar biosynthesis protein FliL compare
Pf6N2E2_1195 +0.5 1.8 hypothetical protein compare
Pf6N2E2_3560 +0.5 2.9 membrane protein, putative compare
Pf6N2E2_5843 +0.5 1.0 hypothetical protein compare
Pf6N2E2_1722 +0.5 2.7 3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157) compare
Pf6N2E2_5806 +0.5 2.1 hypothetical protein compare
Pf6N2E2_2213 +0.5 2.5 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_4139 +0.5 4.2 Integral membrane protein TerC compare
Pf6N2E2_959 +0.5 1.7 putative membrane protein compare
Pf6N2E2_1471 +0.5 1.9 Dienelactone hydrolase and related enzymes compare
Pf6N2E2_5375 +0.5 2.0 Oxidoreductase, short chain dehydrogenase/reductase family compare
Pf6N2E2_351 +0.5 3.2 Aldehyde dehydrogenase (EC 1.2.1.3) compare
Pf6N2E2_5394 +0.5 0.9 Molybdenum cofactor biosynthesis protein MoaE compare
Pf6N2E2_4943 +0.5 1.9 PspA/IM30 family protein compare
Pf6N2E2_2675 +0.5 0.7 ATP-dependent RNA helicase SrmB compare
Pf6N2E2_2577 +0.5 3.3 Flagellar biosynthesis protein FlhB compare
Pf6N2E2_5710 +0.5 3.6 probable membrane protein YPO2362 compare
Pf6N2E2_424 +0.5 2.6 Decarboxylase family protein compare
Pf6N2E2_1423 +0.5 2.7 Gamma-aminobutyrate permease compare
Pf6N2E2_1391 +0.5 1.3 DNA-binding response regulator, LuxR family compare
Pf6N2E2_3667 +0.5 0.9 Heptose kinase WapQ, eukaryotic type compare
Pf6N2E2_2344 +0.5 3.6 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) compare
Pf6N2E2_3983 +0.5 2.8 Membrane bound c-di-GMP receptor LapD compare
Pf6N2E2_5170 +0.4 3.8 FIG00955330: hypothetical protein compare
Pf6N2E2_5169 +0.4 1.7 FIG00954216: hypothetical protein compare
Pf6N2E2_6074 +0.4 1.8 Redox-sensitive transcriptional activator SoxR compare
Pf6N2E2_5739 +0.4 0.5 Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family compare
Pf6N2E2_579 +0.4 1.1 FIG00962753: hypothetical protein compare
Pf6N2E2_4359 +0.4 1.3 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_168 +0.4 2.0 hypothetical protein compare
Pf6N2E2_5860 +0.4 2.9 Branched-chain amino acid transport system carrier protein compare
Pf6N2E2_603 +0.4 1.6 FIG00953934: hypothetical protein compare
Pf6N2E2_3573 +0.4 1.4 HupE-UreJ family metal transporter compare
Pf6N2E2_1591 +0.4 2.3 hypothetical protein compare
Pf6N2E2_5333 +0.4 2.7 Butyryl-CoA dehydrogenase (EC 1.3.99.2) compare
Pf6N2E2_2880 +0.4 1.5 FIG00959696: hypothetical protein compare
Pf6N2E2_2279 +0.4 1.7 FIG00954981: hypothetical protein compare
Pf6N2E2_529 +0.4 2.6 FIG00954439: hypothetical protein compare
Pf6N2E2_2127 +0.4 2.1 Transcriptional regulator, GntR family domain / Aspartate aminotransferase (EC 2.6.1.1) compare
Pf6N2E2_1974 +0.4 2.0 FIG141694: hypothetical protein in PFGI-1-like cluster compare
Pf6N2E2_6060 +0.4 2.0 Propionate catabolism operon transcriptional regulator of GntR family [predicted] compare
Pf6N2E2_1587 +0.4 2.1 Dihydroflavonol-4-reductase (EC 1.1.1.219) compare
Pf6N2E2_4980 +0.4 2.3 hypothetical protein compare
Pf6N2E2_3969 +0.4 0.7 Membrane-fusion protein compare
Pf6N2E2_3595 +0.4 1.8 Large protein containing transglutaminase-like domain compare
Pf6N2E2_2181 +0.4 0.9 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_5499 +0.4 0.7 hypothetical protein compare
Pf6N2E2_2502 +0.4 1.9 O-antigen acetylase compare
Pf6N2E2_3386 +0.4 2.0 hypothetical protein compare
Pf6N2E2_2519 +0.4 0.7 Biosynthetic Aromatic amino acid aminotransferase beta (EC 2.6.1.57) compare
Pf6N2E2_4917 +0.4 1.5 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_4691 +0.4 1.2 hypothetical protein compare
Pf6N2E2_315 +0.4 1.9 probable transmembrane protein compare
Pf6N2E2_2688 +0.4 1.0 YD repeat protein compare
Pf6N2E2_5237 +0.4 0.7 Hypoxanthine-guanine phosphoribosyltransferase (EC 2.4.2.8) compare
Pf6N2E2_494 +0.4 1.4 Transcriptional regulator RutR of pyrimidine catabolism (TetR family) compare
Pf6N2E2_464 +0.4 1.3 Sensory histidine kinase QseC compare
Pf6N2E2_2933 +0.4 1.6 hypothetical protein compare
Pf6N2E2_1271 +0.4 3.3 Acriflavin resistance plasma membrane protein compare
Pf6N2E2_2440 +0.4 0.6 Free methionine-(R)-sulfoxide reductase, contains GAF domain compare
Pf6N2E2_2825 +0.4 1.6 RND efflux system, outer membrane lipoprotein CmeC compare
Pf6N2E2_4087 +0.4 2.7 L-asparaginase (EC 3.5.1.1) (from data) compare
Pf6N2E2_3955 +0.4 2.9 FIG00953394: hypothetical protein compare
Pf6N2E2_2585 +0.4 2.8 Flagellar hook-length control protein FliK compare
Pf6N2E2_3571 +0.4 2.1 Urease accessory protein UreF compare
Pf6N2E2_1833 +0.4 2.2 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) / Enoyl CoA hydratase (EC 4.2.1.17) compare
Pf6N2E2_2 +0.4 1.6 FIG057993:Thioesterase involved in non-ribosomal peptide biosynthesis compare
Pf6N2E2_3982 +0.4 1.1 Tryptophan synthase beta chain like (EC 4.2.1.20) compare
Pf6N2E2_5555 +0.4 0.7 Cold shock protein CspA compare
Pf6N2E2_3957 +0.4 2.3 Putative membrane-bound ClpP-class protease associated with aq_911 compare
Pf6N2E2_813 +0.4 1.7 Response regulator compare
Pf6N2E2_1960 +0.4 2.0 ABC transporter for D-sorbitol, ATPase component (from data) compare
Pf6N2E2_6100 +0.4 1.0 tRNA-Val-TAC compare
Pf6N2E2_5632 +0.4 1.9 Aromatic amino acid transport protein AroP compare
Pf6N2E2_5672 +0.4 1.5 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.78) compare
Pf6N2E2_3226 +0.4 1.3 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf6N2E2_3027 +0.4 0.8 Baseplate assembly protein V compare
Pf6N2E2_2919 +0.4 0.8 FIG00955830: hypothetical protein compare
Pf6N2E2_1560 +0.4 1.1 Glycine cleavage system transcriptional activator GcvA compare
Pf6N2E2_1744 +0.4 2.0 ABC transporter, periplasmic spermidine putrescine-binding protein PotD (TC 3.A.1.11.1) compare


Specific Phenotypes

For 8 genes in this experiment

For carbon source D-Alanine in Pseudomonas fluorescens FW300-N2E2

For carbon source D-Alanine across organisms