Experiment set1IT027 for Pseudomonas fluorescens FW300-N2E2

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L-Phenylalanine carbon source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_4826 -6.6 -7.8 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_3842 -6.4 -6.2 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_4596 -6.3 -12.0 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_4597 -6.2 -11.9 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_3782 -6.1 -6.0 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_4825 -5.8 -11.7 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_3253 -5.7 -8.8 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_71 -5.6 -8.5 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_5176 -5.4 -13.8 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_5175 -5.3 -18.1 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_3783 -5.3 -8.0 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_3839 -5.2 -7.1 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_4047 -5.0 -8.3 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_4564 -4.9 -12.3 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_2217 -4.8 -8.6 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_2629 -4.8 -13.4 Phenylalanine hydroxylase transcriptional activator PhhR conserved
Pf6N2E2_5156 -4.7 -3.3 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_2258 -4.5 -14.9 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_5177 -4.5 -11.0 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_3248 -4.5 -5.9 Probable transmembrane protein compare
Pf6N2E2_77 -4.4 -7.1 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_4071 -4.3 -7.4 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_4048 -4.3 -7.8 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_3841 -4.2 -9.0 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_64 -4.2 -3.8 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_3630 -4.2 -7.9 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_456 -4.0 -12.1 4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) (from data) conserved
Pf6N2E2_4372 -4.0 -8.0 FIG00460773: hypothetical protein compare
Pf6N2E2_4752 -4.0 -14.4 Malate synthase G (EC 2.3.3.9) compare
Pf6N2E2_3251 -3.9 -11.1 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_2753 -3.9 -5.7 HtrA protease/chaperone protein compare
Pf6N2E2_66 -3.8 -9.2 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_3252 -3.8 -6.9 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_5291 -3.8 -19.6 Fumarylacetoacetase (EC 3.7.1.2) compare
Pf6N2E2_5006 -3.8 -10.8 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_5014 -3.8 -2.4 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_2630 -3.7 -7.2 Phenylalanine 4-monooxygenase (EC 1.14.16.1) (from data) conserved
Pf6N2E2_5290 -3.6 -12.2 Homogentisate 1,2-dioxygenase (EC 1.13.11.5) (from data) conserved
Pf6N2E2_4279 -3.6 -13.8 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_4278 -3.6 -11.2 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_3610 -3.6 -3.4 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_3932 -3.5 -6.6 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_5292 -3.5 -5.6 Maleylacetoacetate isomerase (EC 5.2.1.2) (from data) conserved
Pf6N2E2_5723 -3.3 -13.3 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
Pf6N2E2_5178 -3.3 -3.1 CDP-diacylglycerol--serine O-phosphatidyltransferase (EC 2.7.8.8) compare
Pf6N2E2_2074 -3.3 -3.0 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_2218 -3.1 -7.1 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_4803 -3.1 -2.9 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_2073 -3.1 -9.9 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_3940 -3.0 -9.5 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_5527 -3.0 -4.1 Cold shock protein CspC compare
Pf6N2E2_4464 -3.0 -4.2 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases / CDP-6-deoxy-delta-3,4-glucoseen reductase-like compare
Pf6N2E2_4638 -2.8 -5.8 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_5579 -2.8 -6.4 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_2632 -2.8 -5.3 tyrosine aminotransferase (EC 2.6.1.57) (from data) conserved
Pf6N2E2_302 -2.6 -9.2 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_3170 -2.6 -6.6 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_2277 -2.5 -3.7 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_63 -2.5 -4.9 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_5155 -2.4 -4.8 Poly(A) polymerase (EC 2.7.7.19) compare
Pf6N2E2_4453 -2.4 -14.4 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_3461 -2.3 -2.2 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_2588 -2.3 -5.1 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV compare
Pf6N2E2_5242 -2.2 -3.2 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_4277 -2.2 -9.2 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_1381 -2.1 -7.4 Aldehyde dehydrogenase (EC 1.2.1.3) compare
Pf6N2E2_5243 -2.1 -2.9 hypothetical protein compare
Pf6N2E2_3984 -2.1 -10.4 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_4759 -2.0 -12.8 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_4353 -2.0 -7.7 Hydrogen peroxide-inducible genes activator compare
Pf6N2E2_5160 -1.9 -3.0 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_3885 -1.9 -3.8 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
Pf6N2E2_5536 -1.9 -2.7 Holliday junction DNA helicase RuvA compare
Pf6N2E2_4824 -1.9 -5.5 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
Pf6N2E2_2166 -1.8 -10.3 protein of unknown function DUF6, transmembrane compare
Pf6N2E2_3349 -1.8 -2.4 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_2274 -1.8 -6.0 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) compare
Pf6N2E2_3770 -1.7 -3.3 ATP-dependent hsl protease ATP-binding subunit HslU compare
Pf6N2E2_4351 -1.7 -10.5 Predicted signal transduction protein compare
Pf6N2E2_5001 -1.7 -2.6 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) compare
Pf6N2E2_4416 -1.6 -3.5 Tyrosine recombinase XerC compare
Pf6N2E2_4009 -1.6 -7.7 GGDEF domain protein compare
Pf6N2E2_5659 -1.6 -13.3 Acetyl-coenzyme A synthetase (EC 6.2.1.1) compare
Pf6N2E2_1394 -1.5 -5.3 FIG00953323: hypothetical protein compare
Pf6N2E2_2465 -1.5 -4.4 Cys regulon transcriptional activator CysB compare
Pf6N2E2_3346 -1.5 -5.0 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf6N2E2_1387 -1.5 -5.6 Cytochrome C550 (Soluble cytochrome C) compare
Pf6N2E2_5722 -1.5 -3.4 23S rRNA (Uracil-5-) -methyltransferase RumA (EC 2.1.1.-) ## LSU rRNA m(5)U1939 compare
Pf6N2E2_5714 -1.5 -3.5 Flavoprotein WrbA compare
Pf6N2E2_2111 -1.4 -4.2 Dehydrocarnitine CoA-transferase and acetoacetate CoA-transferase, subunit A (from data) compare
Pf6N2E2_2646 -1.4 -1.9 FIG00953416: hypothetical protein compare
Pf6N2E2_5103 -1.3 -1.9 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
Pf6N2E2_3460 -1.3 -2.0 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_3933 -1.3 -5.5 D-2-hydroxyglutarate dehydrogenase compare
Pf6N2E2_4743 -1.3 -1.4 hypothetical protein compare
Pf6N2E2_1395 -1.3 -6.1 Uncharacterized conserved protein compare
Pf6N2E2_6140 -1.3 -1.4 Large Subunit Ribosomal RNA; lsuRNA; LSU rRNA compare
Pf6N2E2_178 -1.2 -1.4 Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) compare
Pf6N2E2_4360 -1.2 -8.2 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
Pf6N2E2_613 -1.2 -2.1 lipoprotein, putative compare
Pf6N2E2_1056 -1.2 -1.1 Quinone oxidoreductase (EC 1.6.5.5) compare
Pf6N2E2_4352 -1.2 -3.4 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf6N2E2_2261 -1.2 -5.7 VacJ-like lipoprotein precursor compare
Pf6N2E2_1396 -1.2 -2.9 ABC transporter, ATP-binding protein compare
Pf6N2E2_4205 -1.2 -3.8 Chromosome (plasmid) partitioning protein ParA compare
Pf6N2E2_4776 -1.2 -8.0 Coenzyme PQQ synthesis protein F compare
Pf6N2E2_2574 -1.2 -3.0 Flagellar synthesis regulator FleN compare
Pf6N2E2_1386 -1.2 -4.8 amino acid ABC transporter, periplasmic substrate-binding protein compare
Pf6N2E2_4928 -1.2 -2.2 Permeases of the major facilitator superfamily compare
Pf6N2E2_2003 -1.2 -2.8 hypothetical protein compare
Pf6N2E2_477 -1.2 -5.0 Branched-chain amino acid aminotransferase (EC 2.6.1.42) compare
Pf6N2E2_2112 -1.1 -4.6 Dehydrocarnitine CoA-transferase and acetoacetate CoA-transferase, subunit B (from data) conserved
Pf6N2E2_279 -1.1 -6.6 Isocitrate lyase (EC 4.1.3.1) compare
Pf6N2E2_2549 -1.1 -2.3 hypothetical protein compare
Pf6N2E2_510 -1.1 -7.1 Predicted transcriptional regulator of the myo-inositol catabolic operon compare
Pf6N2E2_3762 -1.1 -4.8 NADP-dependent malic enzyme (EC 1.1.1.40) compare
Pf6N2E2_5420 -1.1 -6.1 Cytosol aminopeptidase PepA (EC 3.4.11.1) compare
Pf6N2E2_3938 -1.1 -8.2 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf6N2E2_3899 -1.1 -5.2 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) compare
Pf6N2E2_2281 -1.1 -2.2 Beta N-acetyl-glucosaminidase (EC 3.2.1.52) compare
Pf6N2E2_4414 -1.1 -3.7 FIG00953808: hypothetical protein compare
Pf6N2E2_1400 -1.1 -8.0 Sensory box histidine kinase/response regulator compare
Pf6N2E2_2186 -1.1 -4.9 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
Pf6N2E2_1397 -1.1 -7.3 ABC transporter permease protein compare
Pf6N2E2_1399 -1.1 -4.1 Transcriptional regulator, LuxR family compare
Pf6N2E2_5936 -1.0 -2.3 Low molecular weight protein tyrosine phosphatase (EC 3.1.3.48) compare
Pf6N2E2_4057 -1.0 -1.0 lipoprotein, putative compare
Pf6N2E2_5337 -1.0 -4.6 Ubiquinol-cytochrome C reductase iron-sulfur subunit (EC 1.10.2.2) compare
Pf6N2E2_3667 -1.0 -1.7 Heptose kinase WapQ, eukaryotic type compare
Pf6N2E2_4749 -1.0 -3.5 DNA polymerase III epsilon subunit (EC 2.7.7.7) compare
Pf6N2E2_2693 -1.0 -1.9 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.180) compare
Pf6N2E2_3258 -1.0 -4.3 Uncharacterized ABC transporter, periplasmic component YrbD compare
Pf6N2E2_5520 -1.0 -5.4 Sensory box histidine kinase compare
Pf6N2E2_1917 -1.0 -2.6 hypothetical protein compare
Pf6N2E2_1379 -1.0 -4.2 Sensory box histidine kinase/response regulator compare
Pf6N2E2_2487 -1.0 -1.2 FIG00956090: hypothetical protein compare
Pf6N2E2_5677 -1.0 -1.2 Carbon storage regulator compare
Pf6N2E2_3229 -0.9 -3.5 Putative glutathione transporter, ATP-binding component compare
Pf6N2E2_2756 -0.9 -4.3 RNA polymerase sigma-H factor AlgT compare
Pf6N2E2_1705 -0.9 -1.8 Branched-chain amino acid transport ATP-binding protein LivG (TC 3.A.1.4.1) compare
Pf6N2E2_2794 -0.9 -1.7 putative membrane protein compare
Pf6N2E2_3060 -0.9 -1.3 Outer membrane protein H precursor compare
Pf6N2E2_2167 -0.9 -4.7 hypothetical protein compare
Pf6N2E2_5679 -0.9 -4.2 hypothetical protein compare
Pf6N2E2_2552 -0.9 -4.1 Cytochrome c heme lyase subunit CcmH compare
Pf6N2E2_4795 -0.9 -4.7 Acyl-phosphate:glycerol-3-phosphate O-acyltransferase PlsY compare
Pf6N2E2_424 -0.9 -4.1 Decarboxylase family protein compare
Pf6N2E2_5339 -0.9 -4.6 ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit compare
Pf6N2E2_5316 -0.9 -1.3 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_1281 -0.9 -2.5 ATPase involved in DNA repair compare
Pf6N2E2_237 -0.9 -1.5 hypothetical protein compare
Pf6N2E2_3475 -0.9 -1.8 hypothetical protein compare
Pf6N2E2_922 -0.9 -3.0 FIG00794167: hypothetical protein compare
Pf6N2E2_5338 -0.9 -5.5 Ubiquinol--cytochrome c reductase, cytochrome B subunit (EC 1.10.2.2) compare
Pf6N2E2_88 -0.8 -1.9 hypothetical protein compare
Pf6N2E2_622 -0.8 -4.1 BatA (Bacteroides aerotolerance operon) compare
Pf6N2E2_3589 -0.8 -2.4 Lysine decarboxylase family compare
Pf6N2E2_446 -0.8 -4.9 Glutathione reductase (EC 1.8.1.7) compare
Pf6N2E2_3351 -0.8 -2.7 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
Pf6N2E2_4817 -0.8 -7.1 Spermidine Putrescine ABC transporter permease component PotB (TC 3.A.1.11.1) compare
Pf6N2E2_2189 -0.8 -2.8 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
Pf6N2E2_2292 -0.8 -3.0 Universal stress protein family COG0589 compare
Pf6N2E2_2453 -0.8 -5.0 2-keto-3-deoxy-D-arabino-heptulosonate-7- phosphate synthase II (EC 2.5.1.54) conserved
Pf6N2E2_1932 -0.8 -4.0 Transcriptional regulator, IclR family compare
Pf6N2E2_4059 -0.8 -1.1 DNA-binding protein HU-alpha compare
Pf6N2E2_5676 -0.8 -3.4 Aspartokinase (EC 2.7.2.4) compare
Pf6N2E2_1886 -0.8 -1.7 hypothetical protein compare
Pf6N2E2_2312 -0.8 -1.4 Cytochrome c oxidase subunit CcoQ (EC 1.9.3.1) compare
Pf6N2E2_5522 -0.8 -2.3 FIG001943: hypothetical protein YajQ compare
Pf6N2E2_3257 -0.8 -2.5 Uncharacterized ABC transporter, auxiliary component YrbC compare
Pf6N2E2_5841 -0.8 -1.2 GlcG protein compare
Pf6N2E2_623 -0.8 -1.2 FIG00954674: hypothetical protein compare
Pf6N2E2_5524 -0.8 -5.9 Outer membrane porin, OprD family compare
Pf6N2E2_2681 -0.8 -2.6 3-phosphoglycerate kinase compare
Pf6N2E2_2707 -0.8 -2.5 Allophanate hydrolase 2 subunit 1 (EC 3.5.1.54) compare
Pf6N2E2_3271 -0.8 -2.0 Phosphocarrier protein, nitrogen regulation associated compare
Pf6N2E2_2822 -0.8 -3.8 Transcription repressor of multidrug efflux pump acrAB operon, TetR (AcrR) family compare
Pf6N2E2_2640 -0.7 -1.7 Permease of the drug/metabolite transporter (DMT) superfamily compare
Pf6N2E2_2514 -0.7 -2.6 regulator of length of O-antigen component of lipopolysaccharide chains compare
Pf6N2E2_156 -0.7 -1.4 Carbon storage regulator compare
Pf6N2E2_3807 -0.7 -2.7 Histidine utilization repressor compare
Pf6N2E2_1490 -0.7 -1.8 hypothetical protein compare
Pf6N2E2_1323 -0.7 -2.9 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) compare
Pf6N2E2_621 -0.7 -3.6 TPR domain protein in aerotolerance operon compare
Pf6N2E2_5257 -0.7 -4.4 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_4273 -0.7 -4.1 ATP-dependent DNA helicase UvrD/PcrA compare
Pf6N2E2_4599 -0.7 -1.6 Integral membrane protein YggT, involved in response to extracytoplasmic stress (osmotic shock) compare
Pf6N2E2_4579 -0.7 -1.5 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
Pf6N2E2_1382 -0.7 -4.8 Quino(hemo)protein alcohol dehydrogenase, PQQ-dependent (EC 1.1.99.8) compare
Pf6N2E2_5084 -0.7 -5.1 Glutathione-regulated potassium-efflux system ATP-binding protein compare
Pf6N2E2_5328 -0.7 -3.1 FIG00958649: hypothetical protein compare
Pf6N2E2_4761 -0.7 -4.3 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf6N2E2_2165 -0.7 -5.5 Uncharacterized conserved protein compare
Pf6N2E2_4772 -0.7 -4.2 Coenzyme PQQ synthesis protein E compare
Pf6N2E2_3062 -0.7 -2.9 Membrane-associated zinc metalloprotease compare
Pf6N2E2_2467 -0.7 -3.1 5'-nucleotidase (EC 3.1.3.5) compare
Pf6N2E2_2480 -0.7 -0.8 FIG00957636: hypothetical protein compare
Pf6N2E2_1667 -0.7 -2.2 Fumarylacetoacetate hydrolase family protein compare
Pf6N2E2_5150 -0.7 -3.1 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf6N2E2_2706 -0.7 -2.2 Allophanate hydrolase 2 subunit 2 (EC 3.5.1.54) compare


Specific Phenotypes

For 10 genes in this experiment

For carbon source L-Phenylalanine in Pseudomonas fluorescens FW300-N2E2

For carbon source L-Phenylalanine across organisms