Experiment set1IT026 for Sinorhizobium meliloti 1021

Compare to:

L-Glutamine carbon source

200 most important genes:

  gene name fitness t score description  
SMc02766 -8.9 -10.6 tryptophan synthase subunit beta compare
SMc04405 -8.6 -6.0 3-isopropylmalate dehydrogenase compare
SMc02899 -8.6 -8.3 prephenate dehydratase compare
SMc02245 -8.5 -5.9 dihydroorotate dehydrogenase 2 compare
SMc00917 -8.2 -5.6 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
SMc00236 -8.2 -5.6 Indole-3-glycerol phosphate synthase compare
SMc02767 -8.1 -9.7 N-(5'-phosphoribosyl)anthranilate isomerase compare
SMc02569 -8.1 -5.6 imidazole glycerol phosphate synthase subunit HisF compare
SMc01726 -8.1 -7.9 acetylglutamate kinase compare
SMc03797 -8.0 -9.5 homoserine O-succinyltransferase compare
SMc00495 -8.0 -5.0 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
SMc01801 -7.9 -5.1 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) compare
SMc01028 -7.9 -7.7 phosphopyruvate hydratase compare
SMc02717 -7.8 -7.6 2-isopropylmalate synthase compare
SMc04002 -7.8 -9.2 phosphoribosylaminoimidazole carboxylase ATPase subunit compare
SMc00235 -7.7 -7.5 anthranilate phosphoribosyltransferase compare
SMc00918 -7.6 -7.4 ATP phosphoribosyltransferase regulatory subunit compare
SMc02562 -7.6 -5.3 phosphoenolpyruvate carboxykinase compare
SMc02725 -7.6 -11.6 anthranilate synthase compare
SMc03069 -7.6 -4.8 6-phosphogluconolactonase compare
SMc01431 -7.6 -7.4 acetolactate synthase 3 catalytic subunit compare
SMc02217 -7.5 -5.2 O-succinylhomoserine sulfhydrylase compare
SMc02137 -7.5 -5.2 ornithine carbamoyltransferase compare
SMc00493 -7.4 -5.1 phosphoribosylformylglycinamidine synthase I compare
SMc00640 -7.3 -10.0 phosphoserine aminotransferase compare
SMc01494 -7.3 -11.4 phosphoserine phosphatase compare
SMc00614 -7.3 -7.1 phosphoribosylglycinamide formyltransferase compare
SMc02838 -7.3 -8.7 phosphoglyceromutase compare
SMc00293 -7.2 -12.9 homoserine dehydrogenase compare
SMc00711 -7.1 -6.9 cyclohexadienyl dehydrogenase compare
SMc00615 -7.0 -11.6 phosphoribosylaminoimidazole synthetase compare
SMc01843 -7.0 -14.9 5,10-methylenetetrahydrofolate reductase compare
SMc02765 -6.9 -14.1 tryptophan synthase subunit alpha compare
SMc00494 -6.8 -2.5 phosphoribosylformylglycinamidine synthase subunit PurS compare
SMc00412 -6.8 -4.7 orotidine 5'-phosphate decarboxylase compare
SMc03776 -6.7 -4.7 gamma-glutamyl kinase compare
SMc03823 -6.7 -10.8 isopropylmalate isomerase large subunit compare
SMc00488 -6.7 -18.5 phosphoribosylformylglycinamidine synthase II compare
SMc04045 -6.7 -9.2 dihydroxy-acid dehydratase compare
SMc00993 -6.7 -11.8 phosphoribosylamine--glycine ligase compare
SMc03112 -6.6 -19.1 B12-dependent methionine synthase compare
SMc00554 -6.5 -7.8 amidophosphoribosyltransferase compare
SMc03777 -6.5 -8.9 gamma-glutamyl phosphate reductase compare
SMc03826 -6.4 -4.4 argininosuccinate synthase compare
SMc04088 -6.3 -9.5 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase compare
SMc01360 -6.3 -4.4 aspartate carbamoyltransferase catalytic subunit compare
SMc02707 -6.3 -6.6 hypothetical protein compare
SMc02124 -6.2 -16.1 nitrite reductase compare
SMc02755 -6.2 -6.0 S-adenosyl-L-homocysteine hydrolase compare
SMc00131 -6.1 -15.4 transcriptional regulator compare
SMc02123 -6.1 -4.6 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
SMc02425 -6.1 -5.9 transcriptional regulator compare
SMc01004 -5.9 -8.2 phosphoribosyl-AMP cyclohydrolase compare
SMc01361 -5.9 -6.7 dihydroorotase compare
SMc02975 -5.9 -9.5 phosphoenolpyruvate carboxykinase regulator transcription regulator protein compare
SMc02570 -5.9 -7.0 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
SMc00815 -5.8 -3.7 inosine 5'-monophosphate dehydrogenase compare
SMc03229 -5.8 -3.7 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase compare
SMc01054 -5.7 -5.4 required for sulfate utilization, putative electron source for sulfite reductase CysI (from data) compare
SMc04085 -5.7 -3.9 hypothetical protein compare
SMc00090 -5.6 -11.5 sulfate adenylyltransferase compare
SMc03979 -5.5 -3.8 glyceraldehyde-3-phosphate dehydrogenase compare
SMc00486 -5.5 -14.4 Glutaminase (EC 3.5.1.2) (from data) conserved
SMc01880 -5.3 -3.7 pantoate--beta-alanine ligase compare
SMc03763 -5.3 -3.6 cytosine-specific methyltransferase compare
SMa1635 -5.2 -2.8 hypothetical protein compare
SMc02138 -5.2 -9.4 acetylornithine transaminase compare
SMc01206 -5.1 -2.7 queuine tRNA-ribosyltransferase compare
SMc02166 -5.1 -11.4 dihydroorotase compare
SMc01881 -5.0 -5.2 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
SMc02165 -5.0 -8.7 orotate phosphoribosyltransferase compare
SMc01215 -4.9 -3.4 carbamoyl phosphate synthase large subunit compare
SMc01569 -4.9 -2.5 carbamoyl phosphate synthase small subunit compare
SMc02572 -4.9 -3.4 imidazole glycerol phosphate synthase subunit HisH compare
SMc02172 -4.8 -14.3 transcriptional regulator compare
SMc03981 -4.8 -3.4 phosphoglycerate kinase compare
SMc04001 -4.7 -1.7 phosphoribosylaminoimidazole carboxylase catalytic subunit protein compare
SMc00876 -4.6 -8.8 ATP-binding MRP protein compare
SMc00294 -4.6 -10.9 aminotransferase compare
SMc01770 -4.5 -2.0 serine hydroxymethyltransferase compare
SMc00092 -4.5 -12.2 phosphoadenosine phosphosulfate reductase compare
SMc00017 -4.5 -2.3 homoserine kinase compare
SMc03795 -4.4 -2.3 isopropylmalate isomerase small subunit compare
SMc01053 -4.4 -4.6 siroheme synthase compare
SMc00641 -4.4 -6.4 D-3-phosphoglycerate dehydrogenase compare
SM_b21177 -4.4 -10.6 phosphate uptake ABC transporter ATP-binding protein compare
SMc02307 -4.3 -9.8 histidinol dehydrogenase compare
SMc00091 -4.3 -13.6 sulfate adenylyltransferase compare
SM_b21176 -4.1 -7.0 phosphate uptake ABC transporter substrate-binding protein precursor compare
SM_b21174 -3.8 -5.4 phosphate uptake ABC transporter permease compare
SMc01430 -3.6 -10.1 acetolactate synthase 3 regulatory subunit compare
SMc04346 -3.6 -4.6 ketol-acid reductoisomerase compare
SMc03978 -3.5 -5.4 transketolase compare
SM_b21175 -3.5 -4.4 phosphate uptake ABC transporter permease compare
SMc03974 -3.3 -4.5 hypothetical protein compare
SMc01592 -3.3 -10.2 transcriptional regulator compare
SMc02308 -3.2 -2.2 hypothetical protein compare
SMc02058 -3.2 -4.4 YAJC protein compare
SMc00414 -3.0 -14.6 hypothetical protein compare
SMc01951 -3.0 -9.9 high-affinity branched-chain amino acid ABC transporter permease compare
SMc02119 -2.9 -13.3 ABC transporter for L-Glutamine, L-Histidine, and other L-amino acids, permease component 1 (from data) compare
SMc02246 -2.9 -1.5 hypothetical protein compare
SMc02115 -2.9 -1.5 hypothetical protein compare
SMc02118 -2.9 -11.0 ABC transporter for L-Glutamine, L-Histidine, and other L-amino acids, periplasmic substrate-binding component (from data) compare
SMc00982 -2.8 -8.7 dioxygenase compare
SMc01950 -2.8 -13.8 high-affinity branched-chain amino acid ABC transporter permease compare
SMc01441 -2.8 -8.0 membrane bound protease compare
SMc02120 -2.8 -10.0 ABC transporter for L-Glutamine, L-Histidine, and other L-amino acids, permease component 2 (from data) compare
SMc03070 -2.7 -11.1 glucose-6-phosphate 1-dehydrogenase compare
SMc01495 -2.7 -6.9 transcriptional regulator compare
SMc01207 -2.7 -3.2 S-adenosylmethionine--tRNA ribosyltransferase-isomerase compare
SMc01948 -2.6 -5.8 high-affinity branched-chain amino acid ABC transporter ATP-binding protein compare
SMc02833 -2.5 -2.3 penicillin-insensitive murein endopeptidase compare
SMc01440 -2.5 -6.2 hydrolase serine protease transmembrane protein compare
SMc00450 -2.4 -3.8 protoheme IX farnesyltransferase compare
SMc01949 -2.4 -7.6 high-affinity branched-chain amino acid ABC transporter ATP-binding protein conserved
SMc03100 -2.3 -2.1 hypothetical protein compare
SMc00709 -2.2 -5.3 hypothetical protein compare
SMc00191 -2.2 -2.0 hypothetical protein compare
SMc02812 -2.2 -2.1 hypothetical protein compare
SMc04093 -2.1 -14.6 acetyl-CoA synthetase compare
SMc02460 -2.0 -10.3 hypothetical protein compare
SMc00321 -2.0 -6.5 tRNA pseudouridine synthase B compare
SMc01126 -2.0 -12.9 malic enzyme conserved
SMc02227 -2.0 -7.1 fatty oxidation complex enoyl-COA hydratase/3-hydroxyacyl-COA dehydrogenase/3-hydroxybutyryl-COA epimerase compare
SMc02435 -2.0 -4.2 methyltransferase compare
SMc01800 -2.0 -1.8 cytochrome C oxidase assembly transmembrane protein compare
SMc01947 -2.0 -4.4 hypothetical protein compare
SMc00025 -2.0 -3.2 pyruvate phosphate dikinase compare
SMc00838 -2.0 -7.2 hypothetical protein compare
SMc04260 -1.9 -10.9 transcriptional regulator compare
SMa0789 -1.9 -3.8 GntR family transcriptional regulator compare
SM_b21035 -1.9 -7.9 hypothetical protein compare
SM_b21598 -1.9 -8.7 transcriptional regulator compare
SMc00189 -1.9 -7.3 cytochrome C1 protein compare
SMc02363 -1.9 -3.9 cytochrome C-type biogenesis transmembrane protein compare
SMc02121 -1.9 -2.4 ABC transporter for L-Glutamine, L-Histidine, and other L-amino acids, ATPase component (from data) compare
SMc00981 -1.9 -6.9 ferredoxin protein compare
SMc04263 -1.8 -12.5 amino acid carrier transmembrane protein conserved
SMc00963 -1.8 -3.9 hypothetical protein compare
SMc02724 -1.8 -4.7 hypothetical protein compare
SMa1442 -1.8 -6.4 GntR family transcriptional regulator compare
SMc01845 -1.8 -3.1 transglycosylase transmembrane protein compare
SMc02753 -1.7 -2.2 PTS system transporter subunit IIA compare
SMc01852 -1.7 -9.7 pyrophosphate--fructose-6-phosphate 1-phosphotransferase compare
SM_b20773 -1.7 -3.7 GntR family transcriptional regulator compare
SMc01164 -1.6 -8.8 hypothetical protein compare
SMc02983 -1.6 -6.2 ornithine, DAP, or arginine decarboxylase compare
SMc02362 -1.6 -4.2 cytochrome c-type biogenesis protein CcmE compare
SMc02897 -1.6 -3.2 cytochrome C transmembrane protein compare
SMc01595 -1.6 -2.9 sensor histidine kinase transmembrane protein compare
SMc02147 -1.6 -7.7 phosphate regulon sensor histidine kinase transmembrane protein compare
SMc02112 -1.5 -4.9 hypothetical protein compare
SMc02048 -1.5 -4.2 glycine cleavage system protein H compare
SMc02141 -1.5 -3.6 phosphate transporter PhoU compare
SM_b21372 -1.5 -10.7 LacI family transcriptional regulator compare
SMc01505 -1.5 -2.2 hypothetical protein compare
SMc00295 -1.5 -0.7 hypothetical protein compare
SMa2020 -1.5 -5.2 Transcriptional regulator compare
SMc03258 -1.4 -5.6 transcriptional regulator compare
SM_b20148 -1.4 -4.5 transcriptional regulator compare
SM_b20392 -1.4 -5.0 transcriptional regulator NanR compare
SMc02102 -1.4 -3.2 hypothetical protein compare
SMc02228 -1.4 -8.2 acetyl-CoA acetyltransferase compare
SMc01368 -1.4 -5.1 transport transmembrane protein compare
SMc02620 -1.4 -7.4 hypothetical protein compare
SMc02142 -1.3 -5.9 phosphate transporter ATP-binding protein compare
SMc02521 -1.3 -3.0 glycerol-3-phosphate regulon repressor transcription regulator protein compare
SMc02229 -1.3 -8.5 acyl-CoA dehydrogenase compare
SMc04262 -1.3 -5.4 6-phosphogluconate dehydrogenase compare
SMc00247 -1.3 -7.4 phosphatidylcholine synthase compare
SMc02574 -1.3 -2.1 imidazoleglycerol-phosphate dehydratase compare
SMc01007 -1.3 -2.5 hypothetical protein compare
SMc00914 -1.3 -3.8 oxidoreductase compare
SMc03949 -1.2 -3.5 nitrogen regulatory protein compare
SMc01946 -1.2 -6.3 leucine-specific binding protein compare
SMc02641 -1.2 -4.8 UDP-glucose 6-dehydrogenase compare
SMc01438 -1.2 -3.6 protease precursor signal peptide protein compare
SMc00689 -1.2 -4.8 lipoprotein compare
SMc00334 -1.2 -1.4 cytidylate kinase compare
SMc02368 -1.2 -8.3 bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase compare
SMc02049 -1.2 -9.6 glycine dehydrogenase compare
SMc04243 -1.2 -5.6 high-affinity zinc uptake system membrane ABC transporter protein compare
SMc03850 -1.2 -1.4 heme exporter D (cytochrome C-type biogenesis protein) transmembrane compare
SMc02495 -1.2 -2.0 translaldolase compare
SM_b20509 -1.2 -2.6 transcriptional regulator compare
SMc02385 -1.2 -2.8 hypothetical protein compare
SMc00579 -1.2 -2.8 dimethyladenosine transferase compare
SM_b20901 -1.2 -6.0 transcriptional regulator compare
SM_b21633 -1.2 -1.2 enoyl-CoA hydratase compare
SMc01174 -1.2 -7.2 cysteine synthase A compare
SM_b20323 -1.1 -1.2 transcriptional regulator compare
SMc00622 -1.1 -5.9 ribonuclease D protein compare
SM_b21102 -1.1 -7.4 transcriptional regulator compare
SM_b20105 -1.1 -1.4 transcriptional regulator compare
SMc00557 -1.1 -4.2 alanine racemase compare
SMc00012 -1.1 -1.5 cytochrome C oxidase assembly protein compare
SMc00188 -1.0 -6.3 cytochrome B transmembrane protein compare
SMc02505 -1.0 -1.8 hypothetical protein compare
SMc02232 -1.0 -3.3 hypothetical protein compare


Specific Phenotypes

For 16 genes in this experiment

For carbon source L-Glutamine in Sinorhizobium meliloti 1021

For carbon source L-Glutamine across organisms