Experiment set1IT025 for Pseudomonas fluorescens FW300-N2E2

Compare to:

L-Alanine carbon source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_4597 -6.7 -10.3 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_3248 -6.3 -7.2 Probable transmembrane protein compare
Pf6N2E2_77 -6.1 -6.0 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_3782 -6.0 -5.8 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_3253 -5.7 -8.6 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_2277 -5.5 -3.8 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_4390 -5.5 -13.2 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system conserved
Pf6N2E2_4596 -5.5 -13.3 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_4279 -5.5 -16.6 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_3630 -5.2 -8.9 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_4825 -5.0 -12.3 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_71 -5.0 -8.9 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_2753 -4.9 -4.8 HtrA protease/chaperone protein compare
Pf6N2E2_5175 -4.8 -18.5 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_3751 -4.7 -14.7 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_5156 -4.7 -3.2 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_4391 -4.7 -9.4 D-amino acid dehydrogenase small subunit (EC 1.4.99.1) compare
Pf6N2E2_3942 -4.6 -14.4 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
Pf6N2E2_3841 -4.6 -7.9 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_64 -4.6 -4.0 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_3461 -4.6 -2.8 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_3783 -4.5 -7.8 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_5160 -4.3 -2.2 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_4826 -4.3 -9.6 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_3752 -4.3 -20.3 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_4047 -4.3 -9.0 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_4803 -4.2 -2.9 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_4278 -4.2 -15.0 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_5177 -4.2 -12.3 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_2574 -4.2 -3.2 Flagellar synthesis regulator FleN compare
Pf6N2E2_3839 -3.9 -7.0 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_3940 -3.9 -10.8 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_5527 -3.9 -4.1 Cold shock protein CspC compare
Pf6N2E2_4048 -3.9 -7.3 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_4277 -3.8 -12.0 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_3842 -3.8 -4.3 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_5006 -3.8 -9.3 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_5723 -3.8 -13.6 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
Pf6N2E2_4564 -3.7 -12.9 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_4759 -3.6 -17.2 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_3932 -3.5 -5.8 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_3252 -3.4 -8.2 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_3271 -3.4 -3.8 Phosphocarrier protein, nitrogen regulation associated compare
Pf6N2E2_4416 -3.4 -5.1 Tyrosine recombinase XerC compare
Pf6N2E2_4762 -3.3 -4.0 Biotin synthesis protein BioH compare
Pf6N2E2_3661 -3.2 -7.7 hypothetical protein compare
Pf6N2E2_3096 -3.2 -2.0 Periplasmic protein TonB, links inner and outer membranes compare
Pf6N2E2_5666 -3.2 -10.9 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_5459 -3.2 -15.6 D-serine/D-alanine/glycine transporter conserved
Pf6N2E2_1381 -3.2 -7.9 Aldehyde dehydrogenase (EC 1.2.1.3) compare
Pf6N2E2_50 -3.1 -9.0 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_3610 -3.1 -4.8 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_5176 -2.9 -10.9 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_66 -2.9 -7.0 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_3346 -2.9 -7.7 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf6N2E2_3060 -2.9 -3.6 Outer membrane protein H precursor compare
Pf6N2E2_2320 -2.9 -3.9 Heavy-metal-associated domain (N-terminus) and membrane-bounded cytochrome biogenesis cycZ-like domain, possible membrane copper tolerance protein compare
Pf6N2E2_5780 -2.8 -11.4 Periplasmic protease compare
Pf6N2E2_3460 -2.7 -2.7 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_4453 -2.7 -16.6 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_2513 -2.6 -3.9 UDP-glucose dehydrogenase (EC 1.1.1.22) compare
Pf6N2E2_2074 -2.6 -2.0 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_5579 -2.6 -5.5 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_4057 -2.6 -1.3 lipoprotein, putative compare
Pf6N2E2_4763 -2.5 -11.0 Biotin synthesis protein BioC compare
Pf6N2E2_2073 -2.5 -10.5 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_2507 -2.5 -9.1 Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-) compare
Pf6N2E2_5337 -2.4 -7.3 Ubiquinol-cytochrome C reductase iron-sulfur subunit (EC 1.10.2.2) compare
Pf6N2E2_4764 -2.4 -6.3 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_2218 -2.4 -6.3 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_5316 -2.4 -3.5 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_5720 -2.4 -15.4 BarA sensory histidine kinase (= VarS = GacS) compare
Pf6N2E2_5219 -2.4 -8.6 FIG140336: TPR domain protein compare
Pf6N2E2_3251 -2.4 -9.9 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_4638 -2.4 -3.1 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_3270 -2.4 -6.5 Hypothetical ATP-binding protein UPF0042, contains P-loop compare
Pf6N2E2_2022 -2.4 -7.8 BarA-associated response regulator UvrY (= GacA = SirA) compare
Pf6N2E2_2186 -2.3 -7.2 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
Pf6N2E2_5339 -2.3 -7.2 ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit compare
Pf6N2E2_63 -2.2 -4.1 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_4059 -2.2 -1.6 DNA-binding protein HU-alpha compare
Pf6N2E2_4761 -2.2 -10.3 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf6N2E2_1932 -2.2 -5.8 Transcriptional regulator, IclR family compare
Pf6N2E2_2318 -2.1 -9.4 Type cbb3 cytochrome oxidase biogenesis protein CcoI; Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_2217 -2.1 -6.2 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_4071 -2.1 -4.0 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_4372 -2.1 -6.6 FIG00460773: hypothetical protein compare
Pf6N2E2_4187 -2.1 -4.8 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_3264 -2.1 -2.4 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_4159 -2.1 -6.4 Cytochrome c4 compare
Pf6N2E2_2310 -2.1 -11.8 Cytochrome c oxidase subunit CcoN (EC 1.9.3.1) compare
Pf6N2E2_5338 -2.1 -8.9 Ubiquinol--cytochrome c reductase, cytochrome B subunit (EC 1.10.2.2) compare
Pf6N2E2_3170 -2.0 -5.9 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_5430 -2.0 -8.5 Transglycosylase, Slt family compare
Pf6N2E2_4352 -2.0 -3.2 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf6N2E2_4631 -2.0 -9.3 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf6N2E2_3786 -2.0 -3.3 Twin-arginine translocation protein TatC compare
Pf6N2E2_1400 -2.0 -10.9 Sensory box histidine kinase/response regulator compare
Pf6N2E2_3899 -1.9 -7.3 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) compare
Pf6N2E2_2508 -1.9 -5.4 hypothetical protein compare
Pf6N2E2_4206 -1.9 -2.2 Chromosome (plasmid) partitioning protein ParB compare
Pf6N2E2_3835 -1.8 -2.7 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf6N2E2_3826 -1.8 -6.9 Nitrogen regulation protein NR(I) compare
Pf6N2E2_1545 -1.8 -4.8 N-carbamoylputrescine amidase (EC 3.5.1.53) compare
Pf6N2E2_5553 -1.7 -7.0 Quinolinate synthetase (EC 2.5.1.72) compare
Pf6N2E2_2510 -1.7 -3.4 Lipid carrier : UDP-N-acetylgalactosaminyltransferase (EC 2.4.1.-) / Alpha-1,3-N-acetylgalactosamine transferase PglA (EC 2.4.1.-); Putative glycosyltransferase compare
Pf6N2E2_5667 -1.7 -6.6 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_922 -1.7 -3.4 FIG00794167: hypothetical protein compare
Pf6N2E2_1402 -1.7 -6.7 hypothetical protein compare
Pf6N2E2_4541 -1.7 -1.6 hypothetical protein compare
Pf6N2E2_5950 -1.7 -4.6 Phosphate:acyl-ACP acyltransferase PlsX compare
Pf6N2E2_2527 -1.6 -3.8 Oxidoreductase, short chain dehydrogenase/reductase family compare
Pf6N2E2_3062 -1.6 -5.1 Membrane-associated zinc metalloprotease compare
Pf6N2E2_4009 -1.6 -8.5 GGDEF domain protein compare
Pf6N2E2_5342 -1.6 -3.8 21 kDa hemolysin precursor compare
Pf6N2E2_2258 -1.6 -7.4 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_3834 -1.6 -6.7 Lipoprotein NlpD compare
Pf6N2E2_4611 -1.5 -3.5 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_2313 -1.5 -3.7 Cytochrome c oxidase subunit CcoP (EC 1.9.3.1) compare
Pf6N2E2_5027 -1.5 -9.0 AMP nucleosidase (EC 3.2.2.4) compare
Pf6N2E2_3665 -1.5 -1.0 serine/threonine protein kinase compare
Pf6N2E2_2752 -1.5 -8.9 Exported zinc metalloprotease YfgC precursor compare
Pf6N2E2_2264 -1.5 -4.5 NADPH dependent preQ0 reductase (EC 1.7.1.13) compare
Pf6N2E2_3134 -1.5 -1.2 hypothetical protein compare
Pf6N2E2_623 -1.5 -1.5 FIG00954674: hypothetical protein compare
Pf6N2E2_3984 -1.4 -6.8 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_4362 -1.4 -3.2 DNA-directed RNA polymerase omega subunit (EC 2.7.7.6) compare
Pf6N2E2_3384 -1.4 -3.1 Predicted L-lactate dehydrogenase, hypothetical protein subunit YkgG compare
Pf6N2E2_2311 -1.4 -6.4 Cytochrome c oxidase subunit CcoO (EC 1.9.3.1) compare
Pf6N2E2_624 -1.4 -4.5 hypothetical protein PA3071 compare
Pf6N2E2_2317 -1.3 -4.6 Putative analog of CcoH, COG3198 compare
Pf6N2E2_3761 -1.3 -11.8 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) compare
Pf6N2E2_2465 -1.3 -3.7 Cys regulon transcriptional activator CysB compare
Pf6N2E2_2309 -1.3 -1.6 hypothetical protein compare
Pf6N2E2_2852 -1.3 -7.1 GGDEF domain/EAL domain protein compare
Pf6N2E2_5848 -1.3 -4.3 small component of pyruvate transporter (yjcH-like) (from data) compare
Pf6N2E2_3095 -1.3 -1.4 hypothetical protein compare
Pf6N2E2_3349 -1.3 -1.9 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_2178 -1.2 -5.8 FIG00960144: hypothetical protein compare
Pf6N2E2_2526 -1.2 -4.6 Similar to phosphoglycolate phosphatase, clustered with ubiquinone biosynthesis SAM-dependent O-methyltransferase compare
Pf6N2E2_2373 -1.2 -3.1 Type III secretion thermoregulatory protein (LcrF,VirF,transcription regulation of virulence plasmid) compare
Pf6N2E2_5328 -1.2 -4.5 FIG00958649: hypothetical protein compare
Pf6N2E2_1294 -1.2 -2.6 Carbon starvation protein A compare
Pf6N2E2_621 -1.2 -5.7 TPR domain protein in aerotolerance operon compare
Pf6N2E2_5727 -1.2 -5.0 FIG00955360: hypothetical protein compare
Pf6N2E2_5704 -1.2 -5.7 Transcriptional regulatory protein PhoP compare
Pf6N2E2_5403 -1.1 -7.0 ABC transporter for D-Alanine, permease component 2 (from data) compare
Pf6N2E2_4516 -1.1 -6.9 Putrescine transport system permease protein PotH (TC 3.A.1.11.2) compare
Pf6N2E2_3260 -1.1 -3.7 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
Pf6N2E2_955 -1.1 -4.1 FIG00953508: hypothetical protein compare
Pf6N2E2_3383 -1.1 -4.2 Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF compare
Pf6N2E2_3825 -1.1 -3.2 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
Pf6N2E2_4205 -1.1 -2.8 Chromosome (plasmid) partitioning protein ParA compare
Pf6N2E2_3258 -1.1 -4.8 Uncharacterized ABC transporter, periplasmic component YrbD compare
Pf6N2E2_2473 -1.1 -1.3 Major outer membrane lipoprotein I compare
Pf6N2E2_3199 -1.1 -4.2 S-adenosylmethionine:tRNA ribosyltransferase-isomerase (EC 5.-.-.-) compare
Pf6N2E2_2586 -1.1 -1.0 Hpt domain protein compare
Pf6N2E2_4584 -1.1 -3.3 Cell division transporter, ATP-binding protein FtsE (TC 3.A.5.1.1) compare
Pf6N2E2_2072 -1.1 -2.3 hypothetical protein compare
Pf6N2E2_893 -1.1 -2.8 hypothetical protein compare
Pf6N2E2_5536 -1.1 -1.2 Holliday junction DNA helicase RuvA compare
Pf6N2E2_5665 -1.1 -4.9 Succinylornithine transaminase (EC 2.6.1.81) compare
Pf6N2E2_3663 -1.0 -4.3 Glycosyl transferase compare
Pf6N2E2_3659 -1.0 -3.8 Protein fixF compare
Pf6N2E2_248 -1.0 -5.0 hypothetical protein compare
Pf6N2E2_4515 -1.0 -6.8 Putrescine transport ATP-binding protein PotG (TC 3.A.1.11.2) compare
Pf6N2E2_1718 -1.0 -2.5 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) compare
Pf6N2E2_5014 -1.0 -1.2 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_3656 -1.0 -3.9 Probable transcription regulator Mig-14 compare
Pf6N2E2_5405 -1.0 -2.9 ABC transporter for D-Alanine, ATPase component (from data) compare
Pf6N2E2_3885 -1.0 -2.4 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
Pf6N2E2_4360 -1.0 -7.1 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
Pf6N2E2_1821 -1.0 -1.9 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system compare
Pf6N2E2_510 -1.0 -6.7 Predicted transcriptional regulator of the myo-inositol catabolic operon compare
Pf6N2E2_5544 -1.0 -5.3 TPR repeat containing exported protein; Putative periplasmic protein contains a protein prenylyltransferase domain compare
Pf6N2E2_4585 -1.0 -6.1 Cell division protein FtsX compare
Pf6N2E2_309 -1.0 -1.0 FIG00957702: hypothetical protein compare
Pf6N2E2_819 -1.0 -2.7 Response regulator compare
Pf6N2E2_3344 -1.0 -3.1 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) AmpD compare
Pf6N2E2_2435 -0.9 -6.2 Deoxyguanosinetriphosphate triphosphohydrolase (EC 3.1.5.1) compare
Pf6N2E2_5190 -0.9 -5.8 Carbonic anhydrase (EC 4.2.1.1) compare
Pf6N2E2_3382 -0.9 -4.1 Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF compare
Pf6N2E2_156 -0.9 -1.9 Carbon storage regulator compare
Pf6N2E2_622 -0.9 -3.0 BatA (Bacteroides aerotolerance operon) compare
Pf6N2E2_2746 -0.9 -4.2 Outer membrane protein NlpB, lipoprotein component of the protein assembly complex (forms a complex with YaeT, YfiO, and YfgL); Lipoprotein-34 precursor compare
Pf6N2E2_5157 -0.9 -5.5 Two-component sensor CbrA: intrcellular carbon:nitrogen balance compare
Pf6N2E2_1717 -0.9 -5.6 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
Pf6N2E2_2121 -0.9 -2.8 hypothetical protein compare
Pf6N2E2_818 -0.9 -4.5 Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY compare
Pf6N2E2_620 -0.9 -4.7 BatD compare
Pf6N2E2_3198 -0.9 -0.9 tRNA-guanine transglycosylase (EC 2.4.2.29) compare
Pf6N2E2_5093 -0.9 -6.5 ATP-dependent protease La (EC 3.4.21.53) Type II compare
Pf6N2E2_423 -0.9 -1.5 Putative phosphatase YfbT compare
Pf6N2E2_2274 -0.9 -3.3 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) compare
Pf6N2E2_2640 -0.9 -0.8 Permease of the drug/metabolite transporter (DMT) superfamily compare
Pf6N2E2_1776 -0.9 -1.6 Chemotaxis protein CheD compare
Pf6N2E2_4216 -0.9 -2.9 Transcriptional regulator of glmS gene, DeoR family compare
Pf6N2E2_3638 -0.9 -1.8 hypothetical protein compare
Pf6N2E2_4399 -0.9 -4.4 GGDEF domain/EAL domain protein compare
Pf6N2E2_3820 -0.9 -1.3 hypothetical protein compare


Specific Phenotypes

For 5 genes in this experiment

For carbon source L-Alanine in Pseudomonas fluorescens FW300-N2E2

For carbon source L-Alanine across organisms