Experiment set1IT024 for Sinorhizobium meliloti 1021

Compare to:

L-Histidine carbon source

200 most detrimental genes:

  gene name fitness t score description  
SMc03140 +2.1 13.8 transcriptional regulator compare
SMc01419 +1.7 5.4 RNA polymerase sigma factor protein compare
SMc01418 +1.4 9.4 signal peptide protein compare
SMc00794 +1.1 7.5 two-component response regulator compare
SMc02544 +1.1 1.6 hypothetical protein compare
SMc02261 +1.1 4.1 transcriptional regulator compare
SMc01099 +1.0 3.6 tRNA pseudouridine synthase A compare
SMc02365 +1.0 4.4 protease precursor protein compare
SMc00674 +1.0 5.5 histidine utilization repressor transcription regulator protein compare
SMc01504 +1.0 7.3 two-component response regulator compare
SMc01506 +1.0 5.9 RNA polymerase sigma factor compare
SMc02366 +0.9 6.9 transcriptional regulator compare
SMc02693 +0.9 1.1 peptidyl-tRNA hydrolase compare
SMa0113 +0.9 8.2 Sensor histidine kinase compare
SMc02367 +0.9 5.8 sensor histidine kinase transmembrane protein compare
SMa1639 +0.9 2.1 hypothetical protein compare
SMc04391 +0.9 1.6 3-ketoacyl-ACP reductase compare
SMc01428 +0.9 2.1 cold shock transcription regulator protein compare
SM_b21487 +0.8 6.1 cytochrome o ubiquinol oxidase subunit II compare
SMc02095 +0.8 6.3 hypothetical protein compare
SM_b20806 +0.8 3.9 hypothetical protein compare
SMc00976 +0.8 2.5 enoyl-CoA hydratase compare
SMc01364 +0.8 1.2 DNA topoisomerase I compare
SMc02497 +0.8 1.5 hypothetical protein compare
SMa0114 +0.7 5.7 two-component response regulator compare
SMa0398 +0.7 2.6 histidinol dehydrogenase compare
SMc02655 +0.7 3.0 hypothetical protein compare
SMc03127 +0.7 1.7 ABC transporter permease compare
SMc04081 +0.7 5.1 glycosyl transferase (sulfolipid biosynthesis) protein compare
SMc00565 +0.7 1.0 50S ribosomal protein L9 compare
SMc00955 +0.7 5.3 hypothetical protein compare
SMa0575 +0.7 1.3 hypothetical protein compare
SMc04385 +0.7 2.8 L-2-aminoadipate semialdehyde dehydrogenase (EC 1.2.1.31) (from data) compare
SMc02691 +0.7 2.5 membrane transporter compare
SMc02647 +0.7 1.8 transcriptional regulator compare
SM_b20962 +0.7 3.1 phoshomethylpyrimidine kinase compare
SMc04439 +0.7 3.1 glycine betaine transport ATP-binding ABC transporter protein compare
SMc01144 +0.7 2.5 ribonuclease PH compare
SMc00351 +0.7 1.0 hypothetical protein compare
SMc02052 +0.6 0.9 hypothetical protein compare
SM_b20296 +0.6 2.4 permease compare
SMc01826 +0.6 2.2 ABC transporter permease compare
SMa0833 +0.6 1.1 hypothetical protein compare
SMc00458 +0.6 5.0 transcriptional regulator compare
SMc03128 +0.6 1.4 ABC transporter permease compare
SM_b21551 +0.6 1.1 hypothetical protein compare
SMc03228 +0.6 2.7 YciI-like protein compare
SMc03899 +0.6 0.8 hypothetical protein compare
SM_b20273 +0.6 1.9 hypothetical protein compare
SM_b20803 +0.6 2.3 3-deoxy-manno-octulosonate cytidylyltransferase compare
SM_b21347 +0.6 1.5 pectin degradation protein compare
SMc03930 +0.6 1.0 sarcosine oxidase subunit gamma compare
SMc00026 +0.6 3.4 hypothetical protein compare
SMa0400 +0.6 4.3 Dehydrogenase, Zn-dependent compare
SM_b21120 +0.6 2.7 hypothetical protein compare
SMc01223 +0.6 1.5 transcriptional regulator compare
SM_b20026 +0.6 1.4 hypothetical protein compare
SMc04383 +0.6 3.0 putative hydrolase, required for lysine catabolism (from data) compare
SMc01091 +0.6 2.0 hypothetical protein compare
SM_b21679 +0.6 0.8 hypothetical protein compare
SM_b21271 +0.6 3.8 nucleotide-binding protein compare
SMc01041 +0.6 1.9 NIFR3-like protein compare
SM_b20082 +0.5 2.5 hypothetical protein compare
SMc00280 +0.5 1.0 hypothetical protein compare
SMc00225 +0.5 3.0 trans-aconitate 2-methyltransferase compare
SMa0326 +0.5 1.7 short chain alcohol dehydrogenase-related dehydrogenase compare
SMc01275 +0.5 3.1 ribosomal large subunit pseudouridine synthase C protein compare
SMc03880 +0.5 4.0 hypothetical protein compare
SMc02117 +0.5 3.2 cystathionine beta-lyase compare
SMc04220 +0.5 1.0 transcriptional regulator compare
SMc01858 +0.5 1.2 S-adenosyl-methyltransferase MraW compare
SMc01907 +0.5 4.3 hypothetical protein compare
SMa5033 +0.5 0.9 hypothetical protein compare
SMc02145 +0.5 0.9 signal peptide protein compare
SMa1644 +0.5 2.1 ABC transporter permease compare
SMc00470 +0.5 1.6 hypothetical protein compare
SMc03836 +0.5 1.2 acyl-CoA thioesterase i protein compare
SMc03900 +0.5 4.3 cyclic beta-1,2-glucan ABc transporter compare
SMc01417 +0.5 2.3 hypothetical protein compare
SMa0964 +0.5 1.5 hypothetical protein compare
SMc01278 +0.5 2.4 chaperone-like protein compare
SMc00347 +0.5 1.5 nucleoside diphosphate kinase regulator compare
SMc02490 +0.5 2.9 hypothetical protein compare
SMc03124 +0.5 2.3 periplasmic binding ABC transporter protein compare
SMc01089 +0.5 0.9 hypothetical protein compare
SMa0359 +0.5 2.5 hypothetical protein compare
SMa2034 +0.5 0.8 hypothetical protein compare
SMc03111 +0.5 3.1 mannose 6-phosphate isomerase (EC 5.3.1.8) (from data) compare
SMa0846 +0.5 0.9 transposase, fragment compare
SMc00482 +0.5 2.1 hypothetical protein compare
SMa0748 +0.5 1.3 MucR family transcriptional regulator compare
SM_b20041 +0.5 2.1 hypothetical protein compare
SMa0754 +0.5 1.2 hypothetical protein compare
SMa0391 +0.5 2.6 ABC transporter ATP-binding protein compare
SMa1169 +0.5 2.1 hypothetical protein compare
SMa0312 +0.5 1.2 hypothetical protein compare
SMc00916 +0.5 2.5 glutathione S-transferase compare
SMc00150 +0.5 4.0 hypothetical protein compare
SMc04382 +0.4 4.3 beta-(1,2)-glucan production associated transmembrane protein compare
SM_b20294 +0.4 0.9 transcriptional regulator NanR compare
SM_b21489 +0.4 2.4 cytochrome O ubiquinol oxidase subunit III compare
SMa1170 +0.4 1.5 hypothetical protein compare
SMc02051 +0.4 1.3 hypothetical protein compare
SM_b20343 +0.4 1.3 isoquinoline 1-oxidoreductase compare
SM_b20320 +0.4 0.7 TRAP-type large permease component compare
SMc00787 +0.4 2.9 peptide ABC transporter permease compare
SM_b21511 +0.4 1.0 plasmid stability protein compare
SMc02574 +0.4 1.9 imidazoleglycerol-phosphate dehydratase compare
SMc02615 +0.4 1.4 signal peptide protein compare
SMa1297 +0.4 2.1 hypothetical protein compare
SMc01433 +0.4 2.4 hypothetical protein compare
SMa1136 +0.4 1.2 hypothetical protein compare
SMa0211 +0.4 0.8 hypothetical protein compare
SMa1704 +0.4 2.1 hypothetical protein compare
SMa1056 +0.4 0.8 transcriptional regulator compare
SMc00882 +0.4 2.0 2-dehydro-3-deoxy-6-phosphogalactonate aldolase compare
SMc02604 +0.4 1.9 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase compare
SMc00166 +0.4 0.7 oxidoreductase NAD protein compare
SMc02107 +0.4 0.8 hypothetical protein compare
SMa2059 +0.4 2.3 hypothetical protein compare
SM_b20427 +0.4 1.0 amino acid ABC transporter ATP-binding protein compare
SMc03793 +0.4 2.1 citrate lyase subunit beta compare
SM_b20563 +0.4 1.1 hypothetical protein compare
SMc02520 +0.4 3.0 glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) (from data) compare
SMa1124 +0.4 1.6 hypothetical protein compare
SMa0645 +0.4 0.9 hypothetical protein compare
SMc00786 +0.4 3.3 periplasmic dipeptide-binding protein compare
SM_b21642 +0.4 1.6 hypothetical protein compare
SM_b21124 +0.4 2.4 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) (from data) compare
SMa0831 +0.4 2.0 NifX iron-molybdenum cluster-binding protein compare
SMc00820 +0.4 2.1 transcriptional regulator compare
SMa0728 +0.4 2.1 hypothetical protein compare
SMa0599 +0.4 3.1 hypothetical protein compare
SMc01349 +0.4 2.3 hypothetical protein compare
SMc04337 +0.4 2.1 hypothetical protein compare
SM_b21488 +0.4 3.3 cytochrome o ubiquinol oxidase subunit I compare
SMc04345 +0.4 1.4 hypothetical protein compare
SMc01529 +0.4 1.3 peptide ABC transporter ATP-binding protein compare
SMc03961 +0.4 2.2 sulfolipid (UDP-sulfoquinovose) biosynthesis protein compare
SMa0543 +0.4 1.0 hypothetical protein compare
SMa1264 +0.4 1.8 hypothetical protein compare
SM_b21582 +0.4 1.7 exoD-like membrane protein compare
SMa0448 +0.4 0.9 hypothetical protein compare
SM_b21331 +0.4 1.8 hypothetical protein compare
SMc01039 +0.4 1.5 hypothetical protein compare
SMa1078 +0.4 1.1 hypothetical protein compare
SMa2255 +0.4 2.0 hypothetical protein compare
SM_b20215 +0.4 2.1 transcriptional regulator compare
SMc00045 +0.4 1.1 cytochrome C signal peptide protein compare
SM_b20701 +0.4 0.6 hypothetical protein compare
SMa1188 +0.4 1.9 NosX accesory protein compare
SMa1067 +0.4 2.8 transcriptional regulator compare
SM_b20933 +0.4 3.2 two-component sensor histidine kinase compare
SMa1063 +0.4 1.5 hypothetical protein compare
SMc03006 +0.4 0.7 chemotaxis regulator protein compare
SMc01635 +0.4 2.0 oxidoreductase compare
SMa2215 +0.4 1.6 GntR family transcriptional regulator compare
SMc00129 +0.4 2.6 sensor histidine kinase compare
SMc02478 +0.4 2.7 hypothetical protein compare
SMc05011 +0.4 0.8 bacteriophage DNA-binding transcription regulator compare
SMc03781 +0.4 2.2 rRNA large subunit methyltransferase compare
SMa0450 +0.4 0.8 hypothetical protein compare
SM_b20873 +0.4 1.8 ureidoglycolate hydrolase compare
SM_b20909 +0.4 1.3 hypothetical protein compare
SM_b20186 +0.4 1.6 glutathione-dependent formaldehyde-activating protein compare
SMa1223 +0.4 1.1 hypothetical protein compare
SM_b20122 +0.4 1.6 hypothetical protein compare
SMa1184 +0.4 2.1 NosF ATPase compare
SMc00600 +0.4 1.2 molybdopterin MPT converting factor subunit 1 compare
SM_b20616 +0.4 0.8 thiamine biosynthesis oxidoreductase compare
SMa0886 +0.4 0.6 hypothetical protein compare
SMa1093 +0.4 2.1 hypothetical protein compare
SMc00382 +0.4 2.3 aminopeptidase compare
SMa0077 +0.4 2.4 hypothetical protein compare
SMc01244 +0.4 1.3 tRNA-Ala compare
SMc03827 +0.4 1.2 amino acid efflux transmembrane protein compare
SMc03154 +0.4 1.7 hypothetical protein compare
SMc03185 +0.4 2.1 NADPH dehydrogenase quinone reductase transmembrane protein compare
SM_b20074 +0.4 1.5 hypothetical protein compare
SM_b21509 +0.4 1.0 plasmid stability protein compare
SMa2029 +0.4 1.7 amidohydrolase compare
SMc02980 +0.4 0.8 hypothetical protein compare
SM_b22002 +0.4 1.6 epoxide hydrolase compare
SMc00094 +0.4 2.9 betaine aldehyde dehydrogenase compare
SMc00790 +0.4 2.6 peptide ABC transporter ATP-binding protein compare
SMc00959 +0.3 1.1 hypothetical protein compare
SM_b21259 +0.3 2.6 hypothetical protein compare
SM_b20424 +0.3 1.5 succinate-semialdehyde dehydrogenase compare
SMc00109 +0.3 1.8 transcriptional regulator compare
SM_b20692 +0.3 1.3 5-keto-D-gluconate 5-reductase compare
SM_b20603 +0.3 2.6 branched-chain amino acid ABC transporter permease compare
SMc00024 +0.3 1.1 chromosome partition protein compare
SMa0335 +0.3 1.4 3-ketoacyl-ACP reductase compare
SM_b20805 +0.3 2.1 glycosyltransferase compare
SM_b21462 +0.3 1.7 sugar kinase compare
SMc01556 +0.3 0.8 hypothetical protein compare
SMc02389 +0.3 2.5 hypothetical protein compare
SM_b20468 +0.3 2.2 sensory transduction DNA-binding response regulator protein compare
SMc02380 +0.3 1.6 oxidoreductase transmembrane protein compare
SMc03135 +0.3 1.0 amino-acid transport system ATP-binding ABC transporter protein compare


Specific Phenotypes

For 24 genes in this experiment

For carbon source L-Histidine in Sinorhizobium meliloti 1021

For carbon source L-Histidine across organisms