Experiment set1IT022 for Pseudomonas fluorescens FW300-N2E2

Compare to:

L-Histidine carbon source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_4597 -7.1 -8.5 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_4596 -7.1 -8.4 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_77 -6.8 -4.7 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_4071 -6.6 -6.4 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_71 -6.5 -6.4 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_3630 -6.4 -7.7 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_4825 -6.1 -10.2 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_1401 -6.1 -9.3 FIG00955631: hypothetical protein compare
Pf6N2E2_64 -6.0 -5.4 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_4826 -6.0 -9.2 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_5175 -5.9 -17.1 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_3799 -5.7 -6.7 Histidine ammonia-lyase (EC 4.3.1.3) (from data) conserved
Pf6N2E2_3617 -5.7 -6.7 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) compare
Pf6N2E2_4047 -5.6 -5.5 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_1381 -5.6 -10.7 Aldehyde dehydrogenase (EC 1.2.1.3) compare
Pf6N2E2_2753 -5.5 -3.8 HtrA protease/chaperone protein compare
Pf6N2E2_3941 -5.5 -3.8 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf6N2E2_5176 -5.2 -13.8 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_4759 -5.1 -19.0 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_4048 -4.9 -9.5 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_5156 -4.6 -3.2 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_3804 -4.6 -15.3 Cytosine/purine/uracil/thiamine/allantoin permease family protein conserved
Pf6N2E2_3808 -4.5 -9.8 Formiminoglutamic iminohydrolase (EC 3.5.3.13) (from data) conserved
Pf6N2E2_2073 -4.5 -10.3 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_3805 -4.4 -11.8 Urocanate hydratase (EC 4.2.1.49) (from data) conserved
Pf6N2E2_4564 -4.4 -9.1 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_5160 -4.3 -2.7 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_2258 -4.2 -14.2 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_4803 -4.2 -2.8 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_3062 -4.1 -6.6 Membrane-associated zinc metalloprotease compare
Pf6N2E2_66 -4.0 -8.7 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_1400 -4.0 -10.1 Sensory box histidine kinase/response regulator compare
Pf6N2E2_5177 -4.0 -10.2 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_1932 -4.0 -8.4 Transcriptional regulator, IclR family compare
Pf6N2E2_5723 -4.0 -13.1 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
Pf6N2E2_3797 -3.8 -7.9 N-formylglutamate deformylase (EC 3.5.1.68) (from data) conserved
Pf6N2E2_4418 -3.8 -1.7 Diaminopimelate epimerase (EC 5.1.1.7) compare
Pf6N2E2_1402 -3.8 -6.2 hypothetical protein compare
Pf6N2E2_302 -3.7 -6.2 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_50 -3.7 -8.9 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_4638 -3.7 -6.1 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_5006 -3.6 -9.6 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_2074 -3.6 -2.8 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_2574 -3.6 -4.7 Flagellar synthesis regulator FleN compare
Pf6N2E2_5430 -3.6 -11.9 Transglycosylase, Slt family compare
Pf6N2E2_3661 -3.5 -7.7 hypothetical protein compare
Pf6N2E2_3798 -3.5 -7.7 Imidazolonepropionase (EC 3.5.2.7) (from data) conserved
Pf6N2E2_5780 -3.4 -14.6 Periplasmic protease compare
Pf6N2E2_2752 -3.4 -12.8 Exported zinc metalloprotease YfgC precursor compare
Pf6N2E2_4372 -3.4 -8.1 FIG00460773: hypothetical protein compare
Pf6N2E2_2507 -3.3 -9.6 Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-) compare
Pf6N2E2_5579 -3.2 -7.0 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_3762 -3.1 -10.0 NADP-dependent malic enzyme (EC 1.1.1.40) compare
Pf6N2E2_3663 -2.9 -9.7 Glycosyl transferase compare
Pf6N2E2_63 -2.9 -5.2 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_4279 -2.8 -10.5 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_5316 -2.8 -4.1 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_3834 -2.8 -10.5 Lipoprotein NlpD compare
Pf6N2E2_3460 -2.8 -2.7 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_2320 -2.7 -5.9 Heavy-metal-associated domain (N-terminus) and membrane-bounded cytochrome biogenesis cycZ-like domain, possible membrane copper tolerance protein compare
Pf6N2E2_2217 -2.7 -7.8 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_4611 -2.7 -3.6 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_3461 -2.7 -3.2 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_3060 -2.6 -5.4 Outer membrane protein H precursor compare
Pf6N2E2_4077 -2.6 -3.3 cytosolic long-chain acyl-CoA thioester hydrolase family protein compare
Pf6N2E2_5553 -2.5 -9.3 Quinolinate synthetase (EC 2.5.1.72) compare
Pf6N2E2_3801 -2.5 -3.3 Histidine ABC transporter, ATP-binding protein (TC 3.A.1) compare
Pf6N2E2_4752 -2.5 -16.1 Malate synthase G (EC 2.3.3.9) compare
Pf6N2E2_4584 -2.5 -4.3 Cell division transporter, ATP-binding protein FtsE (TC 3.A.5.1.1) compare
Pf6N2E2_3932 -2.5 -2.7 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_3803 -2.4 -6.1 Histidine ABC transporter, histidine-binding protein (TC 3.A.1) conserved
Pf6N2E2_4764 -2.4 -6.0 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_3835 -2.4 -5.2 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf6N2E2_3349 -2.4 -3.9 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_1056 -2.4 -1.4 Quinone oxidoreductase (EC 1.6.5.5) compare
Pf6N2E2_4631 -2.3 -8.1 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf6N2E2_2277 -2.3 -2.1 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_624 -2.2 -8.4 hypothetical protein PA3071 compare
Pf6N2E2_5219 -2.2 -8.8 FIG140336: TPR domain protein compare
Pf6N2E2_3802 -2.2 -2.8 Histidine ABC transporter, permease protein (TC 3.A.1) compare
Pf6N2E2_4362 -2.2 -4.2 DNA-directed RNA polymerase omega subunit (EC 2.7.7.6) compare
Pf6N2E2_4453 -2.2 -15.0 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_5014 -2.2 -2.1 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_2218 -2.2 -5.9 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_4278 -2.2 -9.9 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_3655 -2.1 -12.8 Hypothetical protein FIG015671 in large core OS assembly cluster compare
Pf6N2E2_3170 -2.1 -5.1 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_2313 -2.1 -5.6 Cytochrome c oxidase subunit CcoP (EC 1.9.3.1) compare
Pf6N2E2_2186 -2.1 -6.8 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
Pf6N2E2_3833 -2.0 -4.4 hypothetical protein compare
Pf6N2E2_4187 -2.0 -4.8 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_3656 -2.0 -6.2 Probable transcription regulator Mig-14 compare
Pf6N2E2_622 -2.0 -4.7 BatA (Bacteroides aerotolerance operon) compare
Pf6N2E2_4352 -2.0 -3.8 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf6N2E2_4761 -1.9 -11.1 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf6N2E2_4810 -1.9 -8.3 Glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) compare
Pf6N2E2_3659 -1.9 -5.3 Protein fixF compare
Pf6N2E2_5403 -1.9 -11.1 ABC transporter for D-Alanine, permease component 2 (from data) conserved
Pf6N2E2_620 -1.9 -7.6 BatD compare
Pf6N2E2_625 -1.9 -6.5 MoxR-like ATPase in aerotolerance operon compare
Pf6N2E2_2526 -1.8 -7.2 Similar to phosphoglycolate phosphatase, clustered with ubiquinone biosynthesis SAM-dependent O-methyltransferase compare
Pf6N2E2_621 -1.8 -9.3 TPR domain protein in aerotolerance operon compare
Pf6N2E2_4075 -1.8 -6.5 Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1) compare
Pf6N2E2_4585 -1.8 -10.5 Cell division protein FtsX compare
Pf6N2E2_3984 -1.8 -9.6 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_4277 -1.8 -7.9 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_2508 -1.8 -2.9 hypothetical protein compare
Pf6N2E2_4009 -1.7 -10.3 GGDEF domain protein compare
Pf6N2E2_3800 -1.7 -3.4 Histidine ammonia-lyase (EC 4.3.1.3) compare
Pf6N2E2_5555 -1.7 -2.2 Cold shock protein CspA compare
Pf6N2E2_2756 -1.7 -7.7 RNA polymerase sigma-H factor AlgT compare
Pf6N2E2_3611 -1.7 -1.8 HflC protein compare
Pf6N2E2_5001 -1.7 -2.1 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) compare
Pf6N2E2_5255 -1.7 -10.8 Outer membrane stress sensor protease DegS compare
Pf6N2E2_5242 -1.6 -2.5 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_2586 -1.6 -2.5 Hpt domain protein compare
Pf6N2E2_3271 -1.6 -3.4 Phosphocarrier protein, nitrogen regulation associated compare
Pf6N2E2_2465 -1.6 -3.6 Cys regulon transcriptional activator CysB compare
Pf6N2E2_5405 -1.6 -5.8 ABC transporter for D-Alanine, ATPase component (from data) compare
Pf6N2E2_2318 -1.6 -9.2 Type cbb3 cytochrome oxidase biogenesis protein CcoI; Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_5337 -1.6 -5.6 Ubiquinol-cytochrome C reductase iron-sulfur subunit (EC 1.10.2.2) compare
Pf6N2E2_5727 -1.6 -5.6 FIG00955360: hypothetical protein compare
Pf6N2E2_3346 -1.6 -6.5 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf6N2E2_2588 -1.5 -3.0 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV compare
Pf6N2E2_5404 -1.5 -6.6 ABC transporter for D-Alanine, permease component 1 (from data) conserved
Pf6N2E2_2509 -1.5 -2.4 UDP-glucose 4-epimerase (EC 5.1.3.2) compare
Pf6N2E2_6057 -1.5 -3.1 FIG002781: Alpha-L-glutamate ligase family protein compare
Pf6N2E2_5157 -1.5 -8.5 Two-component sensor CbrA: intrcellular carbon:nitrogen balance compare
Pf6N2E2_4763 -1.5 -8.6 Biotin synthesis protein BioC compare
Pf6N2E2_6059 -1.5 -5.2 FIG008443: hypothetical protein compare
Pf6N2E2_4072 -1.5 -5.6 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
Pf6N2E2_2510 -1.5 -4.2 Lipid carrier : UDP-N-acetylgalactosaminyltransferase (EC 2.4.1.-) / Alpha-1,3-N-acetylgalactosamine transferase PglA (EC 2.4.1.-); Putative glycosyltransferase compare
Pf6N2E2_3942 -1.5 -8.8 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
Pf6N2E2_4762 -1.4 -3.3 Biotin synthesis protein BioH compare
Pf6N2E2_5865 -1.4 -9.8 Chaperone protein HtpG compare
Pf6N2E2_5339 -1.4 -7.1 ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit compare
Pf6N2E2_4351 -1.4 -9.5 Predicted signal transduction protein compare
Pf6N2E2_3521 -1.4 -7.8 Sensor histidine kinase/response regulator compare
Pf6N2E2_4614 -1.4 -4.3 twitching motility protein PilH compare
Pf6N2E2_623 -1.4 -1.8 FIG00954674: hypothetical protein compare
Pf6N2E2_1759 -1.4 -1.9 uncharacterized domain 1 compare
Pf6N2E2_5402 -1.4 -7.8 ABC transporter for D-Alanine, periplasmic substrate-binding component (from data) conserved
Pf6N2E2_2340 -1.4 -5.6 Transcriptional regulator, GntR family compare
Pf6N2E2_3260 -1.4 -6.1 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
Pf6N2E2_5158 -1.4 -3.5 FIG00954153: hypothetical protein compare
Pf6N2E2_51 -1.4 -5.2 hypothetical protein compare
Pf6N2E2_5338 -1.3 -7.1 Ubiquinol--cytochrome c reductase, cytochrome B subunit (EC 1.10.2.2) compare
Pf6N2E2_4059 -1.3 -1.5 DNA-binding protein HU-alpha compare
Pf6N2E2_4416 -1.3 -3.0 Tyrosine recombinase XerC compare
Pf6N2E2_4353 -1.3 -5.7 Hydrogen peroxide-inducible genes activator compare
Pf6N2E2_5524 -1.3 -9.0 Outer membrane porin, OprD family compare
Pf6N2E2_613 -1.3 -2.1 lipoprotein, putative compare
Pf6N2E2_3696 -1.3 -1.5 hypothetical protein compare
Pf6N2E2_5508 -1.3 -1.8 Formyltetrahydrofolate deformylase (EC 3.5.1.10) compare
Pf6N2E2_3258 -1.3 -4.9 Uncharacterized ABC transporter, periplasmic component YrbD compare
Pf6N2E2_5848 -1.3 -3.2 small component of pyruvate transporter (yjcH-like) (from data) compare
Pf6N2E2_4159 -1.2 -4.4 Cytochrome c4 compare
Pf6N2E2_3198 -1.2 -2.5 tRNA-guanine transglycosylase (EC 2.4.2.29) compare
Pf6N2E2_5181 -1.2 -8.6 Paraquat-inducible protein A compare
Pf6N2E2_4206 -1.2 -1.7 Chromosome (plasmid) partitioning protein ParB compare
Pf6N2E2_4478 -1.2 -6.1 FIG019278: hypothetical protein compare
Pf6N2E2_3763 -1.2 -1.5 hypothetical protein compare
Pf6N2E2_5527 -1.2 -2.3 Cold shock protein CspC compare
Pf6N2E2_4074 -1.2 -8.3 Phosphate transport system permease protein PstC (TC 3.A.1.7.1) compare
Pf6N2E2_2506 -1.2 -9.2 nucleotide sugar epimerase/dehydratase WbpM compare
Pf6N2E2_5331 -1.1 -5.2 ATPase, AFG1 family compare
Pf6N2E2_6058 -1.1 -5.1 FIG139976: hypothetical protein compare
Pf6N2E2_2310 -1.1 -7.1 Cytochrome c oxidase subunit CcoN (EC 1.9.3.1) compare
Pf6N2E2_5841 -1.1 -1.5 GlcG protein compare
Pf6N2E2_6065 -1.1 -1.9 ABC transporter in pyoverdin gene cluster, periplasmic component compare
Pf6N2E2_3869 -1.1 -7.8 Branched-chain amino acid transport protein AzlC compare
Pf6N2E2_2442 -1.1 -8.4 sensor histidine kinase/response regulator compare
Pf6N2E2_2010 -1.1 -1.8 hypothetical protein compare
Pf6N2E2_3569 -1.1 -1.9 hypothetical protein compare
Pf6N2E2_2261 -1.1 -6.0 VacJ-like lipoprotein precursor compare
Pf6N2E2_3885 -1.1 -3.5 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
Pf6N2E2_5111 -1.1 -3.4 FKBP-type peptidyl-prolyl cis-trans isomerase SlpA (EC 5.2.1.8) compare
Pf6N2E2_5878 -1.1 -5.5 FIG002571: 4-hydroxybenzoyl-CoA thioesterase domain protein compare
Pf6N2E2_5877 -1.0 -2.5 Phosphohistidine phosphatase SixA compare
Pf6N2E2_5771 -1.0 -5.8 FKBP-type peptidyl-prolyl cis-trans isomerase FklB (EC 5.2.1.8) compare
Pf6N2E2_180 -1.0 -3.9 Transcriptional regulator, MerR family compare
Pf6N2E2_504 -1.0 -3.1 DNA-binding response regulator compare
Pf6N2E2_2575 -1.0 -4.3 Flagellar biosynthesis protein FlhF compare
Pf6N2E2_4084 -1.0 -5.3 Transcriptional regulator compare
Pf6N2E2_2536 -1.0 -1.5 Fumarate hydratase class II (EC 4.2.1.2) compare
Pf6N2E2_510 -1.0 -6.7 Predicted transcriptional regulator of the myo-inositol catabolic operon compare
Pf6N2E2_5183 -1.0 -7.7 Paraquat-inducible protein B compare
Pf6N2E2_3613 -1.0 -5.8 GTP-binding protein HflX compare
Pf6N2E2_3132 -1.0 -3.0 FIG00954548: hypothetical protein compare
Pf6N2E2_6001 -1.0 -5.9 Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
Pf6N2E2_2473 -0.9 -1.4 Major outer membrane lipoprotein I compare
Pf6N2E2_5544 -0.9 -5.2 TPR repeat containing exported protein; Putative periplasmic protein contains a protein prenylyltransferase domain compare
Pf6N2E2_5593 -0.9 -2.6 Leucyl-tRNA synthetase compare
Pf6N2E2_5243 -0.9 -1.8 hypothetical protein compare
Pf6N2E2_5536 -0.9 -1.5 Holliday junction DNA helicase RuvA compare
Pf6N2E2_3692 -0.9 -7.1 Selenoprotein O and cysteine-containing homologs compare
Pf6N2E2_4097 -0.9 -6.3 FIG00953365: hypothetical protein compare
Pf6N2E2_3314 -0.9 -7.1 Dipeptide transport ATP-binding protein DppF (TC 3.A.1.5.2) compare
Pf6N2E2_2071 -0.9 -2.0 hypothetical protein compare
Pf6N2E2_2309 -0.9 -1.5 hypothetical protein compare


Specific Phenotypes

For 18 genes in this experiment

For carbon source L-Histidine in Pseudomonas fluorescens FW300-N2E2

For carbon source L-Histidine across organisms