Experiment set1IT022 for Pseudomonas fluorescens FW300-N1B4

Compare to:

D-Fructose carbon source

200 most important genes:

  gene name fitness t score description  
Pf1N1B4_15 -4.2 -2.9 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf1N1B4_6 -4.0 -3.9 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf1N1B4_1408 -3.6 -4.3 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf1N1B4_2880 -3.6 -10.6 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf1N1B4_1307 -3.5 -2.4 3-dehydroquinate dehydratase II (EC 4.2.1.10) compare
Pf1N1B4_1534 -3.3 -16.7 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf1N1B4_2303 -3.3 -13.6 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf1N1B4_1831 -3.3 -11.1 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf1N1B4_2879 -3.2 -6.7 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf1N1B4_2545 -3.1 -12.5 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
Pf1N1B4_1067 -3.1 -4.8 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf1N1B4_602 -3.1 -4.2 NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) compare
Pf1N1B4_1533 -3.1 -7.9 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf1N1B4_1434 -3.1 -7.9 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf1N1B4_2548 -3.0 -6.7 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf1N1B4_2549 -3.0 -9.3 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf1N1B4_2338 -3.0 -7.2 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf1N1B4_1830 -3.0 -8.0 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf1N1B4_2486 -2.9 -3.4 hypothetical protein compare
Pf1N1B4_742 -2.9 -7.8 Argininosuccinate synthase (EC 6.3.4.5) compare
Pf1N1B4_1624 -2.9 -8.6 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf1N1B4_2384 -2.9 -9.1 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf1N1B4_2009 -2.9 -4.8 LysR family transcriptional regulator PA5437 compare
Pf1N1B4_5666 -2.9 -3.8 Oxidoreductase probably involved in sulfite reduction compare
Pf1N1B4_1146 -2.8 -7.9 fructose-specific PTS system (fructose 1-phosphate forming), EI, Hpr, and EII-A components (from data) conserved
Pf1N1B4_1627 -2.8 -5.0 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf1N1B4_350 -2.8 -6.7 Chorismate mutase I (EC 5.4.99.5) / Prephenate dehydratase (EC 4.2.1.51) compare
Pf1N1B4_2547 -2.7 -3.2 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
Pf1N1B4_769 -2.7 -5.4 Aerobic glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) compare
Pf1N1B4_1565 -2.7 -4.4 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf1N1B4_5665 -2.7 -5.8 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf1N1B4_2282 -2.6 -8.7 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf1N1B4_1144 -2.6 -8.9 PTS system, fructose-specific IIB component (EC 2.7.1.69) / PTS system, fructose-specific IIC component (EC 2.7.1.69) conserved
Pf1N1B4_847 -2.6 -9.1 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf1N1B4_1315 -2.6 -7.9 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) compare
Pf1N1B4_3506 -2.6 -7.6 Cysteine synthase B (EC 2.5.1.47) compare
Pf1N1B4_1626 -2.5 -7.6 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf1N1B4_2011 -2.5 -8.2 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf1N1B4_2878 -2.5 -7.9 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf1N1B4_2010 -2.5 -6.0 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf1N1B4_716 -2.4 -4.3 Probable thiol oxidoreductase with 2 cytochrome c heme-binding sites compare
Pf1N1B4_275 -2.4 -2.8 Organic hydroperoxide resistance transcriptional regulator compare
Pf1N1B4_1617 -2.4 -7.3 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (EC 5.4.2.1) compare
Pf1N1B4_12 -2.4 -7.1 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf1N1B4_5330 -2.4 -2.8 hypothetical protein compare
Pf1N1B4_2337 -2.4 -5.0 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf1N1B4_327 -2.4 -2.7 hypothetical protein compare
Pf1N1B4_2272 -2.3 -4.3 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf1N1B4_2858 -2.2 -9.5 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf1N1B4_4065 -2.2 -7.4 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf1N1B4_2850 -2.2 -6.9 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf1N1B4_257 -2.2 -5.9 sensor histidine kinase/response regulator compare
Pf1N1B4_3518 -2.1 -3.4 Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) compare
Pf1N1B4_2487 -2.1 -8.0 Biotin synthase (EC 2.8.1.6) compare
Pf1N1B4_3812 -2.1 -7.5 Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) compare
Pf1N1B4_58 -2.0 -6.3 Transaldolase (EC 2.2.1.2) compare
Pf1N1B4_3849 -1.9 -4.3 Transcriptional regulator, GntR family compare
Pf1N1B4_3081 -1.8 -14.7 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
Pf1N1B4_652 -1.8 -7.9 Sensory box histidine kinase compare
Pf1N1B4_2280 -1.8 -7.5 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf1N1B4_1906 -1.8 -3.4 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) compare
Pf1N1B4_2684 -1.8 -2.8 Uncharacterized protein, similar to the N-terminal domain of Lon protease compare
Pf1N1B4_1668 -1.8 -4.8 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
Pf1N1B4_3697 -1.7 -6.5 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf1N1B4_1535 -1.7 -3.4 hypothetical protein compare
Pf1N1B4_4957 -1.7 -2.1 Transcriptional regulator, TetR family compare
Pf1N1B4_688 -1.7 -2.1 FIG00955483: hypothetical protein compare
Pf1N1B4_762 -1.6 -5.5 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf1N1B4_4648 -1.6 -2.8 transcriptional regulator, MerR family compare
Pf1N1B4_846 -1.6 -1.9 hypothetical protein compare
Pf1N1B4_5512 -1.6 -1.9 hypothetical protein compare
Pf1N1B4_2021 -1.6 -2.3 hypothetical protein compare
Pf1N1B4_1113 -1.4 -4.9 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf1N1B4_2857 -1.4 -3.2 Poly(A) polymerase (EC 2.7.7.19) compare
Pf1N1B4_4437 -1.4 -2.8 hypothetical protein compare
Pf1N1B4_1590 -1.4 -4.7 Histidine utilization repressor compare
Pf1N1B4_1328 -1.4 -2.5 Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) compare
Pf1N1B4_1008 -1.4 -1.6 FIG006045: Sigma factor, ECF subfamily compare
Pf1N1B4_3241 -1.4 -2.2 hypothetical protein compare
Pf1N1B4_3499 -1.3 -1.6 hypothetical protein compare
Pf1N1B4_3143 -1.3 -2.7 RecA protein compare
Pf1N1B4_611 -1.3 -2.6 CoA transferase, CAIB/BAIF family compare
Pf1N1B4_1625 -1.3 -2.7 FIG00956267: hypothetical protein compare
Pf1N1B4_4335 -1.3 -1.9 Putative translation initiation inhibitor, yjgF family compare
Pf1N1B4_2568 -1.2 -2.5 Translation elongation factor Tu compare
Pf1N1B4_522 -1.2 -2.8 HlyD family secretion protein compare
Pf1N1B4_2102 -1.2 -1.6 hypothetical protein compare
Pf1N1B4_1057 -1.2 -2.5 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf1N1B4_412 -1.2 -2.4 L-arabinose 1-dehydrogenase / D-galactose 1-dehydrogenase (EC 1.1.1.46; EC 1.1.1.48) (from data) compare
Pf1N1B4_4486 -1.2 -2.5 Outer membrane protein (porin) compare
Pf1N1B4_3656 -1.2 -1.6 Eukaryotic-type low-affinity urea transporter compare
Pf1N1B4_717 -1.2 -4.9 Iron-regulated protein A precursor compare
Pf1N1B4_958 -1.2 -2.2 Stringent starvation protein B compare
Pf1N1B4_4038 -1.1 -1.9 NADH-ubiquinone oxidoreductase chain E (EC 1.6.5.3) compare
Pf1N1B4_2706 -1.1 -2.4 FIG00954871: hypothetical protein compare
Pf1N1B4_4929 -1.1 -2.4 Opine oxidase subunit B compare
Pf1N1B4_5302 -1.1 -2.6 hypothetical protein compare
Pf1N1B4_2859 -1.1 -8.0 Two-component sensor CbrA: intrcellular carbon:nitrogen balance compare
Pf1N1B4_1566 -1.1 -4.8 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf1N1B4_4030 -1.1 -2.6 NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3) compare
Pf1N1B4_718 -1.1 -4.6 outer membrane component of uptake system, probably for ferrous iron (from data) compare
Pf1N1B4_419 -1.1 -1.5 Transcriptional regulator, TetR family compare
Pf1N1B4_4531 -1.1 -1.6 FIG01221261: hypothetical protein compare
Pf1N1B4_372 -1.1 -2.3 UDP-galactose-lipid carrier transferase (EC 2.-.-.-) compare
Pf1N1B4_4993 -1.1 -2.9 Arabinose efflux permease compare
Pf1N1B4_5393 -1.1 -1.9 hypothetical protein compare
Pf1N1B4_2739 -1.1 -1.2 acetyltransferase, GNAT family compare
Pf1N1B4_669 -1.1 -2.7 INTEGRAL MEMBRANE PROTEIN (Rhomboid family) compare
Pf1N1B4_4317 -1.1 -1.9 DNA/RNA non-specific endonuclease compare
Pf1N1B4_715 -1.1 -3.6 Iron-regulated protein A precursor compare
Pf1N1B4_1317 -1.1 -2.2 Sensor histidine kinase/response regulator compare
Pf1N1B4_4715 -1.0 -2.0 Transcriptional regulator compare
Pf1N1B4_724 -1.0 -2.0 DNA-binding response regulator ColR compare
Pf1N1B4_102 -1.0 -1.9 Methyl-accepting chemotaxis protein I (serine chemoreceptor protein) compare
Pf1N1B4_414 -1.0 -2.7 transcriptional regulator compare
Pf1N1B4_2005 -1.0 -1.1 ATP-dependent DNA helicase UvrD/PcrA compare
Pf1N1B4_115 -1.0 -1.8 Membrane protein mosC compare
Pf1N1B4_4563 -1.0 -1.9 Sulfate transporter compare
Pf1N1B4_2734 -1.0 -1.1 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system compare
Pf1N1B4_5255 -1.0 -1.5 hypothetical protein compare
Pf1N1B4_5814 -1.0 -2.5 putative membrane protein compare
Pf1N1B4_2491 -1.0 -2.6 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf1N1B4_501 -1.0 -1.8 Flp pilus assembly protein RcpC/CpaB compare
Pf1N1B4_4585 -1.0 -2.2 Putative Isoquinoline 1-oxidoreductase subunit, Mll3835 protein compare
Pf1N1B4_644 -1.0 -1.4 Cold shock protein CspC compare
Pf1N1B4_3273 -1.0 -1.6 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
Pf1N1B4_2377 -1.0 -4.2 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf1N1B4_5059 -1.0 -1.9 Transcriptional regulator, LysR family compare
Pf1N1B4_5460 -0.9 -2.0 TolA protein compare
Pf1N1B4_5724 -0.9 -1.7 High-affinity iron permease compare
Pf1N1B4_2225 -0.9 -6.1 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) compare
Pf1N1B4_2488 -0.9 -4.6 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf1N1B4_5265 -0.9 -1.8 hypothetical protein compare
Pf1N1B4_3130 -0.9 -1.9 Bacteriophage protein GP46 compare
Pf1N1B4_2479 -0.9 -1.8 Glycine cleavage system transcriptional antiactivator GcvR compare
Pf1N1B4_1403 -0.9 -4.3 3'-to-5' exoribonuclease RNase R compare
Pf1N1B4_2948 -0.9 -1.6 FIG00954698: hypothetical protein compare
Pf1N1B4_2252 -0.9 -2.0 Organosulfonate utilization protein SsuF compare
Pf1N1B4_3799 -0.9 -2.3 1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51) compare
Pf1N1B4_164 -0.9 -1.8 ADP-ribosylglycohydrolase family protein compare
Pf1N1B4_2105 -0.9 -1.7 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf1N1B4_3889 -0.9 -1.5 hypothetical protein compare
Pf1N1B4_1653 -0.9 -4.2 Branched-chain amino acid transport protein AzlC compare
Pf1N1B4_7 -0.9 -3.0 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
Pf1N1B4_4473 -0.9 -1.7 Homoserine/homoserine lactone efflux protein compare
Pf1N1B4_5611 -0.9 -1.8 L-carnitine dehydratase/bile acid-inducible protein F (EC 2.8.3.16) compare
Pf1N1B4_2612 -0.9 -2.4 Putative transport protein compare
Pf1N1B4_438 -0.9 -2.9 hypothetical protein compare
Pf1N1B4_403 -0.9 -1.2 FIG00965925: hypothetical protein compare
Pf1N1B4_4118 -0.9 -1.9 Cyn operon transcriptional activator compare
Pf1N1B4_2401 -0.9 -1.1 Lipoprotein, putative compare
Pf1N1B4_1806 -0.9 -2.1 FIG00953743: hypothetical protein compare
Pf1N1B4_31 -0.9 -2.1 Probable Co/Zn/Cd efflux system membrane fusion protein compare
Pf1N1B4_3328 -0.8 -1.5 Rhodanese-like domain protein compare
Pf1N1B4_3711 -0.8 -3.7 Cobyric acid synthase (EC 6.3.5.10) compare
Pf1N1B4_2209 -0.8 -4.4 Exopolyphosphatase (EC 3.6.1.11) compare
Pf1N1B4_2173 -0.8 -1.5 Diaminopimelate epimerase (EC 5.1.1.7) compare
Pf1N1B4_3785 -0.8 -1.5 FOG: Ankyrin repeat compare
Pf1N1B4_324 -0.8 -1.5 Glycosyl transferase, group 2 family protein compare
Pf1N1B4_3742 -0.8 -1.4 Oxidoreductase, zinc-binding compare
Pf1N1B4_722 -0.8 -1.4 SAM-dependent methyltransferases compare
Pf1N1B4_612 -0.8 -2.3 DNA-3-methyladenine glycosylase II (EC 3.2.2.21) compare
Pf1N1B4_5187 -0.8 -1.3 5S RNA compare
Pf1N1B4_5768 -0.8 -1.9 Heme d1 biosynthesis protein NirD compare
Pf1N1B4_32 -0.8 -2.2 Transcriptional regulator, TetR family compare
Pf1N1B4_4412 -0.8 -2.0 Tartrate dehydrogenase (EC 1.1.1.93) @ Tartrate decarboxylase (EC 4.1.1.73) @ D-malic enzyme (EC 1.1.1.83) compare
Pf1N1B4_3713 -0.8 -1.3 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) compare
Pf1N1B4_401 -0.8 -2.3 GCN5-related N-acetyltransferase (EC 2.3.1.57) compare
Pf1N1B4_3234 -0.8 -2.0 Beta-ketoadipyl CoA thiolase (EC 2.3.1.-) compare
Pf1N1B4_5720 -0.8 -1.5 hypothetical protein compare
Pf1N1B4_5624 -0.8 -1.9 Lipase precursor (EC 3.1.1.3) compare
Pf1N1B4_5644 -0.8 -2.6 amino acid ABC transporter, permease protein compare
Pf1N1B4_4550 -0.8 -1.8 beta-ketoacyl synthase, putative compare
Pf1N1B4_2031 -0.8 -3.8 Aldose 1-epimerase compare
Pf1N1B4_3722 -0.8 -2.1 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf1N1B4_733 -0.8 -1.3 Methionyl-tRNA synthetase (EC 6.1.1.10) compare
Pf1N1B4_5058 -0.8 -2.2 D-galactarate permease compare
Pf1N1B4_824 -0.8 -2.4 POSSIBLE MEMBRANE PROTEIN compare
Pf1N1B4_381 -0.8 -1.4 hypothetical protein compare
Pf1N1B4_5072 -0.8 -2.1 Glycerol-3-phosphate regulon repressor compare
Pf1N1B4_904 -0.8 -1.4 DNA-binding protein HU-beta compare
Pf1N1B4_5014 -0.8 -1.3 Glutathione reductase (EC 1.8.1.7) compare
Pf1N1B4_2727 -0.8 -2.2 Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) compare
Pf1N1B4_4931 -0.8 -1.4 Glutarate-semialdehyde dehydrogenase (EC 1.2.1.20); Succinate-semialdehyde dehydrogenase [NADP+] (EC 1.2.1.79) compare
Pf1N1B4_2112 -0.8 -5.7 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
Pf1N1B4_6037 -0.8 -1.8 L-asparaginase (EC 3.5.1.1) compare
Pf1N1B4_5561 -0.8 -1.6 hypothetical protein compare
Pf1N1B4_2712 -0.8 -2.7 tRNA-i(6)A37 methylthiotransferase compare
Pf1N1B4_4596 -0.8 -1.4 Hydroxyacylglutathione hydrolase (EC 3.1.2.6) compare
Pf1N1B4_1 -0.8 -1.8 Colicin V production protein compare
Pf1N1B4_27 -0.8 -2.0 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf1N1B4_152 -0.8 -2.1 ABC transporter, permease protein compare
Pf1N1B4_5898 -0.8 -2.0 hypothetical protein compare
Pf1N1B4_4874 -0.7 -1.2 hypothetical protein compare
Pf1N1B4_4143 -0.7 -1.5 hypothetical protein compare
Pf1N1B4_1683 -0.7 -0.9 Alpha-ketoglutarate-dependent taurine dioxygenase (EC 1.14.11.17) compare
Pf1N1B4_5350 -0.7 -2.2 hypothetical protein compare
Pf1N1B4_5851 -0.7 -1.8 Transcriptional regulator, RpiR family compare
Pf1N1B4_2674 -0.7 -1.2 hypothetical protein compare
Pf1N1B4_4029 -0.7 -1.9 NADH-ubiquinone oxidoreductase chain M (EC 1.6.5.3) compare


Specific Phenotypes

For 2 genes in this experiment

For carbon source D-Fructose in Pseudomonas fluorescens FW300-N1B4

For carbon source D-Fructose across organisms