Experiment set1IT022 for Sinorhizobium meliloti 1021

Compare to:

L-Malic acid disodium salt monohydrate carbon source

200 most important genes:

  gene name fitness t score description  
SMc02838 -9.0 -6.2 phosphoglyceromutase compare
SMc04405 -8.4 -5.8 3-isopropylmalate dehydrogenase compare
SMc02245 -8.3 -5.7 dihydroorotate dehydrogenase 2 compare
SMc02766 -8.2 -13.8 tryptophan synthase subunit beta compare
SMc00236 -8.2 -5.6 Indole-3-glycerol phosphate synthase compare
SMc00917 -8.1 -5.6 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
SMc00640 -8.0 -5.5 phosphoserine aminotransferase compare
SMc01028 -7.9 -7.7 phosphopyruvate hydratase compare
SMc02569 -7.9 -5.5 imidazole glycerol phosphate synthase subunit HisF compare
SMc01801 -7.9 -5.2 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) compare
SMc00235 -7.8 -7.6 anthranilate phosphoribosyltransferase compare
SMc02899 -7.7 -11.8 prephenate dehydratase compare
SMc03797 -7.6 -10.5 homoserine O-succinyltransferase compare
SMc02767 -7.6 -10.4 N-(5'-phosphoribosyl)anthranilate isomerase compare
SMc01843 -7.4 -13.4 5,10-methylenetetrahydrofolate reductase compare
SMc00614 -7.3 -7.1 phosphoribosylglycinamide formyltransferase compare
SMc02137 -7.3 -5.0 ornithine carbamoyltransferase compare
SMc04045 -7.3 -7.1 dihydroxy-acid dehydratase compare
SMc04026 -7.3 -10.0 glutamate synthase compare
SMc02572 -7.2 -5.3 imidazole glycerol phosphate synthase subunit HisH compare
SMc02725 -7.2 -12.0 anthranilate synthase compare
SMc00711 -7.0 -6.8 cyclohexadienyl dehydrogenase compare
SMc00993 -7.0 -9.6 phosphoribosylamine--glycine ligase compare
SMc02717 -6.9 -12.5 2-isopropylmalate synthase compare
SMc03823 -6.9 -12.8 isopropylmalate isomerase large subunit compare
SMc04028 -6.9 -16.0 glutamate synthase compare
SMc01431 -6.9 -13.2 acetolactate synthase 3 catalytic subunit compare
SMc01726 -6.8 -8.1 acetylglutamate kinase compare
SMc01494 -6.8 -10.3 phosphoserine phosphatase compare
SMa1635 -6.7 -2.6 hypothetical protein compare
SMc00918 -6.6 -11.0 ATP phosphoribosyltransferase regulatory subunit compare
SMc00412 -6.6 -4.5 orotidine 5'-phosphate decarboxylase compare
SMc02765 -6.6 -12.4 tryptophan synthase subunit alpha compare
SMc00554 -6.5 -9.0 amidophosphoribosyltransferase compare
SM_b21175 -6.5 -6.0 phosphate uptake ABC transporter permease compare
SMc00615 -6.5 -11.3 phosphoribosylaminoimidazole synthetase compare
SMc02165 -6.4 -7.6 orotate phosphoribosyltransferase compare
SMc01360 -6.3 -4.4 aspartate carbamoyltransferase catalytic subunit compare
SMc01361 -6.3 -6.1 dihydroorotase compare
SMc03112 -6.3 -19.2 B12-dependent methionine synthase compare
SMc02574 -6.3 -7.4 imidazoleglycerol-phosphate dehydratase compare
SMc02217 -6.2 -8.5 O-succinylhomoserine sulfhydrylase compare
SMc03826 -6.2 -4.3 argininosuccinate synthase compare
SMc02562 -5.9 -10.4 phosphoenolpyruvate carboxykinase compare
SMc03069 -5.9 -4.7 6-phosphogluconolactonase compare
SMc00495 -5.9 -5.7 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
SM_b21174 -5.9 -7.2 phosphate uptake ABC transporter permease compare
SMc01004 -5.8 -7.5 phosphoribosyl-AMP cyclohydrolase compare
SMc04002 -5.7 -8.5 phosphoribosylaminoimidazole carboxylase ATPase subunit compare
SMc00488 -5.7 -15.7 phosphoribosylformylglycinamidine synthase II compare
SMc03229 -5.6 -3.7 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase compare
SMc02570 -5.6 -6.5 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
SMc03777 -5.5 -10.4 gamma-glutamyl phosphate reductase compare
SMc00493 -5.5 -8.4 phosphoribosylformylglycinamidine synthase I compare
SMc00641 -5.5 -8.4 D-3-phosphoglycerate dehydrogenase compare
SM_b21176 -5.5 -6.5 phosphate uptake ABC transporter substrate-binding protein precursor compare
SMc04088 -5.4 -8.0 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase compare
SMc03979 -5.4 -3.7 glyceraldehyde-3-phosphate dehydrogenase compare
SMc01880 -5.3 -3.7 pantoate--beta-alanine ligase compare
SMc00494 -5.2 -2.8 phosphoribosylformylglycinamidine synthase subunit PurS compare
SMc03763 -5.0 -3.5 cytosine-specific methyltransferase compare
SMc02307 -5.0 -10.7 histidinol dehydrogenase compare
SMc03776 -5.0 -4.8 gamma-glutamyl kinase compare
SMc01215 -5.0 -3.4 carbamoyl phosphate synthase large subunit compare
SMc01569 -4.9 -2.6 carbamoyl phosphate synthase small subunit compare
SMc04001 -4.6 -1.8 phosphoribosylaminoimidazole carboxylase catalytic subunit protein compare
SMc01770 -4.5 -2.1 serine hydroxymethyltransferase compare
SMc00293 -4.5 -6.2 homoserine dehydrogenase compare
SMc03981 -4.5 -3.6 phosphoglycerate kinase compare
SMc00017 -4.4 -2.3 homoserine kinase compare
SMc03978 -4.4 -4.3 transketolase compare
SMc02246 -4.4 -1.7 hypothetical protein compare
SM_b21177 -4.3 -10.3 phosphate uptake ABC transporter ATP-binding protein compare
SM_b20612 -4.2 -13.0 C4-dicarboxylate transport sensor protein conserved
SMc00131 -4.2 -16.0 transcriptional regulator compare
SMc02166 -4.2 -9.7 dihydroorotase compare
SM_b20613 -4.1 -9.2 C4-dicarboxylate transport transcriptional regulator compare
SMc02138 -3.9 -4.9 acetylornithine transaminase compare
SMc00294 -3.9 -10.0 aminotransferase compare
SMc02707 -3.8 -5.3 hypothetical protein compare
SM_b20611 -3.8 -13.5 C4-dicarboxylate transporter DctA conserved
SMc01139 -3.6 -6.6 RNA polymerase factor sigma-54 compare
SMc02755 -3.6 -10.1 S-adenosyl-L-homocysteine hydrolase compare
SMc01054 -3.6 -6.9 required for sulfate utilization, putative electron source for sulfite reductase CysI (from data) compare
SMc04346 -3.4 -4.6 ketol-acid reductoisomerase compare
SMc03795 -3.4 -2.5 isopropylmalate isomerase small subunit compare
SMc01441 -3.2 -6.9 membrane bound protease compare
SMc02124 -3.2 -15.5 nitrite reductase compare
SMc01881 -3.2 -3.6 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
SMc01053 -3.1 -6.3 siroheme synthase compare
SMc02123 -3.0 -6.2 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
SMc01440 -2.9 -8.9 hydrolase serine protease transmembrane protein compare
SMc00876 -2.7 -7.1 ATP-binding MRP protein compare
SMc00090 -2.7 -13.1 sulfate adenylyltransferase compare
SMc00092 -2.6 -12.4 phosphoadenosine phosphosulfate reductase compare
SMc02058 -2.6 -5.7 YAJC protein compare
SMc00963 -2.5 -7.1 hypothetical protein compare
SMc00091 -2.4 -11.8 sulfate adenylyltransferase compare
SMc00815 -2.3 -3.3 inosine 5'-monophosphate dehydrogenase compare
SMc00169 -1.9 -13.6 malic enzyme compare
SMc02909 -1.9 -2.9 transglycosylase transmembrane protein compare
SMc02778 -1.8 -1.6 hydroxyacid aldolase compare
SMc02753 -1.8 -2.1 PTS system transporter subunit IIA compare
SM_b20293 -1.8 -2.1 hypothetical protein compare
SMc02505 -1.7 -2.4 hypothetical protein compare
SMc02683 -1.7 -2.6 hypothetical protein compare
SMc00914 -1.7 -5.5 oxidoreductase compare
SMc02983 -1.6 -6.3 ornithine, DAP, or arginine decarboxylase compare
SMc01147 -1.6 -4.1 coproporphyrinogen III oxidase compare
SMa0144 -1.6 -1.4 hypothetical protein compare
SMc03850 -1.6 -1.1 heme exporter D (cytochrome C-type biogenesis protein) transmembrane compare
SMc02363 -1.5 -3.3 cytochrome C-type biogenesis transmembrane protein compare
SMc01183 -1.5 -1.9 LexA repressor compare
SMc04242 -1.5 -2.4 zinc uptake regulation protein compare
SMc00709 -1.4 -5.0 hypothetical protein compare
SMc00361 -1.4 -4.4 hypothetical protein compare
SMc02856 -1.4 -10.1 penicillin-binding protein compare
SMc01206 -1.4 -2.0 queuine tRNA-ribosyltransferase compare
SMc01438 -1.3 -3.8 protease precursor signal peptide protein compare
SM_b21173 -1.3 -1.8 hypothetical protein compare
SMc02833 -1.3 -2.8 penicillin-insensitive murein endopeptidase compare
SMc00067 -1.2 -7.0 outer-membranne lipoprotein compare
SMc02786 -1.2 -6.0 translocase transmembrane protein compare
SMc00619 -1.2 -1.5 hypothetical protein compare
SMc00352 -1.2 -1.9 acetyltransferase compare
SMc02172 -1.2 -6.1 transcriptional regulator compare
SMc01097 -1.2 -3.1 hypothetical protein compare
SMc03980 -1.2 -3.4 hypothetical protein compare
SMc00414 -1.2 -8.3 hypothetical protein compare
SMc00288 -1.1 -5.5 signal peptide protein compare
SMc01501 -1.1 -1.9 mannitol 2-dehydrogenase compare
SMc02495 -1.1 -1.4 translaldolase compare
SMc00450 -1.1 -1.8 protoheme IX farnesyltransferase compare
SMc02102 -1.1 -4.0 hypothetical protein compare
SMc01430 -1.1 -2.6 acetolactate synthase 3 regulatory subunit compare
SMc02543 -1.1 -4.6 hypothetical protein compare
SMc00492 -1.0 -1.1 hypothetical protein compare
SMa1625 -1.0 -3.0 LysR family transcriptional regulator compare
SMc04348 -1.0 -1.7 transcriptional regulator compare
SMc02434 -1.0 -3.4 hypothetical protein compare
SMc00166 -1.0 -1.5 oxidoreductase NAD protein compare
SMc00838 -1.0 -5.1 hypothetical protein compare
SMc03100 -1.0 -0.8 hypothetical protein compare
SMc01260 -1.0 -3.4 transcriptional regulator compare
SM_b21035 -0.9 -4.9 hypothetical protein compare
SMc04454 -0.9 -4.2 ABC transporter ATP-binding protein compare
SMc01368 -0.9 -4.5 transport transmembrane protein compare
SMa0789 -0.9 -2.5 GntR family transcriptional regulator compare
SMc01208 -0.9 -2.2 peptidyl-prolyl cis-trans isomerase B protein compare
SMc00856 -0.9 -1.2 hypothetical protein compare
SMc00987 -0.9 -2.6 hypothetical protein compare
SMc00982 -0.9 -4.4 dioxygenase compare
SMc02573 -0.9 -1.0 hypothetical protein compare
SMc00579 -0.9 -3.5 dimethyladenosine transferase compare
SMc02435 -0.9 -1.8 methyltransferase compare
SMc02451 -0.9 -1.7 hypothetical protein compare
SMc03993 -0.8 -2.3 hypothetical protein compare
SMc02901 -0.8 -0.9 hypothetical protein compare
SMc01929 -0.8 -2.2 hypothetical protein compare
SMc01768 -0.8 -2.6 transcriptional regulator compare
SMc02582 -0.8 -2.2 hypothetical protein compare
SMc01578 -0.8 -4.9 aspartate aminotransferase compare
SMc02894 -0.8 -1.0 hypothetical protein compare
SMc03258 -0.8 -4.0 transcriptional regulator compare
SM_b20509 -0.8 -2.5 transcriptional regulator compare
SMc01007 -0.8 -1.6 hypothetical protein compare
SMc02850 -0.8 -2.5 DNA polymerase I compare
SM_b20450 -0.8 -5.7 regulatory protein compare
SMa2168 -0.8 -1.4 tRNA-Met compare
SM_b21551 -0.8 -1.0 hypothetical protein compare
SMc01187 -0.8 -1.1 rare lipoprotein A compare
SMc00823 -0.8 -1.6 hypothetical protein compare
SM_b20823 -0.8 -4.3 cell surface saccharide synthesis protein compare
SMc03949 -0.7 -2.6 nitrogen regulatory protein compare
SM_b21509 -0.7 -2.2 plasmid stability protein compare
SMc04432 -0.7 -2.9 hypothetical protein compare
SMc01471 -0.7 -2.0 cytochrome C oxidase assembly factor transmembrane protein compare
SMc01495 -0.7 -3.1 transcriptional regulator compare
SMc00150 -0.7 -6.1 hypothetical protein compare
SMc01342 -0.7 -2.9 hypothetical protein compare
SMc02659 -0.7 -2.3 GTP pyrophosphokinase (ATP:GTP 3'-pyrophosphotransferase) protein compare
SMc02107 -0.7 -1.0 hypothetical protein compare
SMc02253 -0.7 -3.2 salicylate biosynthesis protein compare
SMc01842 -0.7 -0.7 methyltransferase transcription regulator protein compare
SMc00580 -0.7 -1.9 4-hydroxythreonine-4-phosphate dehydrogenase compare
SMc00513 -0.7 -3.1 amino acid-binding periplasmic protein compare
SM_b20055 -0.7 -1.5 transcriptional regulator compare
SMa1442 -0.7 -2.4 GntR family transcriptional regulator compare
SMa0905 -0.7 -1.1 hypothetical protein compare
SMc04000 -0.7 -0.4 hypothetical protein compare
SMc02713 -0.7 -1.1 RNA polymerase sigma-E factor (sigma-24) protein compare
SM_b20909 -0.7 -1.6 hypothetical protein compare
SMa2065 -0.7 -2.4 hypothetical protein compare
SMc01454 -0.7 -4.7 hypothetical protein compare
SMc02338 -0.7 -1.5 periplasmic binding ABC transporter protein compare
SMc04296 -0.7 -0.6 cell division protein FtsZ compare
SM_b20392 -0.7 -3.0 transcriptional regulator NanR compare
SMc00073 -0.7 -1.7 hypothetical protein compare
SM_b20701 -0.7 -0.8 hypothetical protein compare
SMc01207 -0.6 -1.0 S-adenosylmethionine--tRNA ribosyltransferase-isomerase compare


Specific Phenotypes

For 2 genes in this experiment

For carbon source L-Malic acid disodium salt monohydrate in Sinorhizobium meliloti 1021

For carbon source L-Malic acid disodium salt monohydrate across organisms