Experiment set1IT021 for Sinorhizobium meliloti 1021

Compare to:

D-Sorbitol carbon source

200 most important genes:

  gene name fitness t score description  
SMc02245 -8.4 -5.8 dihydroorotate dehydrogenase 2 compare
SMc02572 -8.2 -6.0 imidazole glycerol phosphate synthase subunit HisH compare
SMc00917 -8.1 -5.6 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
SMc01726 -8.0 -7.8 acetylglutamate kinase compare
SMc01801 -8.0 -5.2 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) compare
SMc02899 -7.8 -10.8 prephenate dehydratase compare
SMc00235 -7.7 -7.5 anthranilate phosphoribosyltransferase compare
SMc02137 -7.4 -5.1 ornithine carbamoyltransferase compare
SMc00993 -7.4 -8.8 phosphoribosylamine--glycine ligase compare
SMc02766 -7.4 -17.8 tryptophan synthase subunit beta compare
SMc00640 -7.3 -10.0 phosphoserine aminotransferase compare
SMc02725 -7.1 -13.6 anthranilate synthase compare
SMc01843 -7.1 -14.4 5,10-methylenetetrahydrofolate reductase compare
SMc03797 -6.9 -11.6 homoserine O-succinyltransferase compare
SMc01431 -6.9 -14.1 acetolactate synthase 3 catalytic subunit compare
SMc00494 -6.9 -2.6 phosphoribosylformylglycinamidine synthase subunit PurS compare
SMc02767 -6.8 -7.8 N-(5'-phosphoribosyl)anthranilate isomerase compare
SMc00918 -6.8 -11.4 ATP phosphoribosyltransferase regulatory subunit compare
SMc03895 -6.7 -19.7 pyruvate carboxylase compare
SMc04028 -6.6 -20.1 glutamate synthase compare
SMa1635 -6.6 -2.5 hypothetical protein compare
SMc00495 -6.6 -5.5 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
SMc02569 -6.6 -5.9 imidazole glycerol phosphate synthase subunit HisF compare
SMc00236 -6.5 -5.8 Indole-3-glycerol phosphate synthase compare
SMc00614 -6.5 -9.0 phosphoribosylglycinamide formyltransferase compare
SMc02765 -6.4 -10.9 tryptophan synthase subunit alpha compare
SMc01494 -6.4 -11.4 phosphoserine phosphatase compare
SMc04045 -6.4 -10.6 dihydroxy-acid dehydratase compare
SMc04002 -6.3 -6.0 phosphoribosylaminoimidazole carboxylase ATPase subunit compare
SMc03112 -6.3 -17.5 B12-dependent methionine synthase compare
SMc00615 -6.2 -9.1 phosphoribosylaminoimidazole synthetase compare
SMc00293 -6.2 -15.3 homoserine dehydrogenase compare
SMc00493 -6.2 -8.5 phosphoribosylformylglycinamidine synthase I compare
SMc02717 -6.2 -16.5 2-isopropylmalate synthase compare
SMc04405 -6.2 -10.4 3-isopropylmalate dehydrogenase compare
SMc03823 -6.1 -11.6 isopropylmalate isomerase large subunit compare
SMc02217 -6.1 -9.3 O-succinylhomoserine sulfhydrylase compare
SMc00488 -6.1 -19.7 phosphoribosylformylglycinamidine synthase II compare
SMc03070 -6.0 -10.0 glucose-6-phosphate 1-dehydrogenase compare
SMc01361 -6.0 -6.8 dihydroorotase compare
SMc02570 -5.9 -6.4 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
SMc02164 -5.9 -4.9 fructokinase compare
SMc01360 -5.8 -5.7 aspartate carbamoyltransferase catalytic subunit compare
SMc04026 -5.8 -9.5 glutamate synthase compare
SMc01004 -5.7 -8.7 phosphoribosyl-AMP cyclohydrolase compare
SMc03826 -5.7 -5.5 argininosuccinate synthase compare
SMc00554 -5.6 -12.0 amidophosphoribosyltransferase compare
SMc03777 -5.3 -9.4 gamma-glutamyl phosphate reductase compare
SMc00963 -5.3 -7.5 hypothetical protein compare
SMc01054 -5.3 -4.9 required for sulfate utilization, putative electron source for sulfite reductase CysI (from data) compare
SMc02755 -5.3 -7.3 S-adenosyl-L-homocysteine hydrolase compare
SMc02123 -5.3 -5.3 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
SMc02165 -5.3 -10.2 orotate phosphoribosyltransferase compare
SMc02307 -5.2 -10.5 histidinol dehydrogenase compare
SMc04088 -5.1 -7.4 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase compare
SMc01215 -5.1 -3.5 carbamoyl phosphate synthase large subunit compare
SMc01569 -4.9 -2.6 carbamoyl phosphate synthase small subunit compare
SMc03981 -4.9 -6.7 phosphoglycerate kinase compare
SMc00131 -4.9 -15.4 transcriptional regulator compare
SMc01880 -4.9 -4.7 pantoate--beta-alanine ligase compare
SMc02124 -4.8 -16.0 nitrite reductase compare
SMc02166 -4.8 -14.2 dihydroorotase compare
SMc02574 -4.7 -6.8 imidazoleglycerol-phosphate dehydratase compare
SMc00090 -4.7 -10.7 sulfate adenylyltransferase compare
SMc00412 -4.7 -6.2 orotidine 5'-phosphate decarboxylase compare
SMc01770 -4.6 -2.1 serine hydroxymethyltransferase compare
SMc03978 -4.5 -4.4 transketolase compare
SMc00017 -4.5 -2.3 homoserine kinase compare
SMc01881 -4.5 -4.3 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
SM_b21176 -4.5 -6.8 phosphate uptake ABC transporter substrate-binding protein precursor compare
SMc02246 -4.5 -1.7 hypothetical protein compare
SMc03795 -4.4 -2.3 isopropylmalate isomerase small subunit compare
SMc00711 -4.3 -5.9 cyclohexadienyl dehydrogenase compare
SMc00641 -4.3 -7.1 D-3-phosphoglycerate dehydrogenase compare
SMc02707 -4.2 -7.7 hypothetical protein compare
SMc02138 -4.1 -8.8 acetylornithine transaminase compare
SMc00092 -4.1 -16.3 phosphoadenosine phosphosulfate reductase compare
SMc03763 -4.1 -5.6 cytosine-specific methyltransferase compare
SMc00876 -4.0 -8.5 ATP-binding MRP protein compare
SMc02983 -4.0 -10.3 ornithine, DAP, or arginine decarboxylase compare
SMc01850 -3.9 -4.3 hypothetical protein compare
SMc00302 -3.9 -4.8 hypothetical protein compare
SMc00815 -3.9 -3.2 inosine 5'-monophosphate dehydrogenase compare
SMc03979 -3.8 -2.6 glyceraldehyde-3-phosphate dehydrogenase compare
SMc00091 -3.7 -15.3 sulfate adenylyltransferase compare
SMc01206 -3.7 -3.3 queuine tRNA-ribosyltransferase compare
SMc03776 -3.6 -3.7 gamma-glutamyl kinase compare
SMc01124 -3.6 -9.9 PII uridylyl-transferase compare
SMc00294 -3.6 -14.4 aminotransferase compare
SM_b21175 -3.5 -4.9 phosphate uptake ABC transporter permease compare
SMc04346 -3.5 -4.0 ketol-acid reductoisomerase compare
SM_b21177 -3.4 -8.2 phosphate uptake ABC transporter ATP-binding protein compare
SMc01622 -3.4 -7.6 oxidoreductase compare
SMc01053 -3.4 -5.4 siroheme synthase compare
SMc02140 -3.3 -2.6 phosphate regulon transcriptional regulatory protein compare
SMc01500 -3.1 -4.0 sorbitol dehydrogenase compare
SMc01430 -3.0 -7.9 acetolactate synthase 3 regulatory subunit compare
SMc03068 -2.9 -12.2 phosphogluconate dehydratase compare
SMc00414 -2.9 -11.7 hypothetical protein compare
SMc01578 -2.7 -10.0 aspartate aminotransferase compare
SM_b21174 -2.6 -7.1 phosphate uptake ABC transporter permease compare
SMc02172 -2.6 -9.5 transcriptional regulator compare
SMc02169 -2.5 -3.1 ABC transporter ATP-binding protein compare
SMc00334 -2.5 -3.4 cytidylate kinase compare
SMc01833 -2.4 -3.6 hypothetical protein compare
SMc02147 -2.4 -11.1 phosphate regulon sensor histidine kinase transmembrane protein compare
SMc02858 -2.4 -1.2 chaperone protein DnaJ compare
SMc02232 -2.4 -4.3 hypothetical protein compare
SMc04001 -2.4 -1.5 phosphoribosylaminoimidazole carboxylase catalytic subunit protein compare
SMc03229 -2.4 -2.3 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase compare
SMc01028 -2.3 -13.7 phosphopyruvate hydratase compare
SMc00726 -2.2 -1.4 thiol:disulfide interchange redox-active center transmembrane protein compare
SMc04005 -2.2 -10.3 pyruvate kinase compare
SMc00296 -2.2 -11.3 POLY3-hydroxybutyrate polymerase compare
SMc01499 -2.1 -10.2 ATP-binding transport ABC transporter protein conserved
SMc01368 -2.1 -7.0 transport transmembrane protein compare
SMc02141 -2.0 -3.7 phosphate transporter PhoU compare
SMc00450 -2.0 -3.3 protoheme IX farnesyltransferase compare
SMc01496 -2.0 -8.9 sorbitol-binding periplasmic protein conserved
SMc01498 -1.9 -8.7 sorbitol/mannitol transport inner membrane protein conserved
SMc00295 -1.9 -2.1 hypothetical protein compare
SMc01497 -1.9 -6.1 sorbitol/mannitol transport inner membrane transmembrane protein conserved
SMc01147 -1.8 -4.7 coproporphyrinogen III oxidase compare
SMc02234 -1.8 -4.4 hypothetical protein compare
SMc02724 -1.8 -4.3 hypothetical protein compare
SMc02833 -1.6 -2.5 penicillin-insensitive murein endopeptidase compare
SMc00982 -1.6 -8.1 dioxygenase compare
SMc00405 -1.6 -7.1 hypothetical protein compare
SMc02058 -1.5 -4.2 YAJC protein compare
SMc03878 -1.5 -3.9 acetoacetyl-CoA reductase compare
SMc03069 -1.5 -2.5 6-phosphogluconolactonase compare
SMc01621 -1.5 -3.5 L-fuculose phosphate aldolase compare
SMc03974 -1.5 -3.6 hypothetical protein compare
SMc02434 -1.5 -2.6 hypothetical protein compare
SMc01187 -1.4 -2.7 rare lipoprotein A compare
SMc03973 -1.4 -7.6 hypothetical protein compare
SMc02167 -1.4 -3.9 fructose transport system kinase compare
SMc02838 -1.4 -5.6 phosphoglyceromutase compare
SMc02142 -1.4 -6.2 phosphate transporter ATP-binding protein compare
SM_b20323 -1.4 -1.3 transcriptional regulator compare
SMc01043 -1.4 -7.7 nitrogen assimilation regulatory protein compare
SMc02229 -1.4 -8.0 acyl-CoA dehydrogenase compare
SMc00619 -1.4 -2.2 hypothetical protein compare
SMc03100 -1.4 -1.3 hypothetical protein compare
SMc01041 -1.4 -3.9 NIFR3-like protein compare
SMc02985 -1.4 -7.6 hypothetical protein compare
SMc02228 -1.3 -6.2 acetyl-CoA acetyltransferase compare
SMc03046 -1.3 -4.3 transcriptional regulator compare
SMc02144 -1.2 -4.0 phosphate ABC transporter permease compare
SMc01503 -1.2 -8.4 sugar kinase conserved
SMc03924 -1.2 -6.7 glycogen synthase compare
SMa1924 -1.2 -1.0 hypothetical protein compare
SMc02170 -1.2 -2.8 ABC transporter permease compare
SMa2020 -1.2 -4.3 Transcriptional regulator compare
SM_b20563 -1.2 -2.8 hypothetical protein compare
SMc02171 -1.2 -3.0 periplasmic binding ABC transporter protein compare
SMa1002 -1.1 -2.0 hypothetical protein compare
SMc02143 -1.1 -3.3 phosphate ABC transporter permease compare
SMc02115 -1.1 -1.0 hypothetical protein compare
SM_b20994 -1.1 -3.3 hypothetical protein compare
SM_b20942 -1.1 -3.5 UDP glucose 4-epimerase compare
SM_b21133 -1.1 -7.9 sulfate ABC transporter substrate-binding protein compare
SMc00981 -1.1 -5.1 ferredoxin protein compare
SM_b20293 -1.1 -1.4 hypothetical protein compare
SMc01119 -1.1 -1.9 hypothetical protein compare
SMc04000 -1.0 -0.7 hypothetical protein compare
SMc01139 -1.0 -4.8 RNA polymerase factor sigma-54 compare
SMc02683 -1.0 -2.4 hypothetical protein compare
SMc03980 -1.0 -3.7 hypothetical protein compare
SMc00647 -1.0 -3.0 ribosomal large subunit pseudouridine synthase compare
SMc02677 -1.0 -6.0 pyrroline-5-carboxylate reductase compare
SM_b20955 -1.0 -3.5 endo-beta-1,3-1,4-glycanase compare
SM_b21131 -1.0 -5.6 sulfate ABC transporter permease compare
SM_b20324 -1.0 -5.5 ThuR, regulatory protein for trehalosemaltose transport system compare
SMc01580 -1.0 -3.7 hypothetical protein compare
SMc01207 -1.0 -2.1 S-adenosylmethionine--tRNA ribosyltransferase-isomerase compare
SM_b21132 -0.9 -3.8 sulfate ABC transporter permease compare
SMc02640 -0.9 -3.6 UDP-glucuronic acid epimerase compare
SMc01208 -0.9 -2.5 peptidyl-prolyl cis-trans isomerase B protein compare
SMc03850 -0.9 -1.2 heme exporter D (cytochrome C-type biogenesis protein) transmembrane compare
SMc02102 -0.9 -2.6 hypothetical protein compare
SM_b21130 -0.9 -4.9 sulfate ABC transporter ATP-binding protein compare
SMc00838 -0.9 -4.5 hypothetical protein compare
SMc00072 -0.9 -1.5 peroxiredoxin protein compare
SMc04042 -0.9 -4.0 monophosphatase compare
SMc02050 -0.9 -2.8 trigger factor compare
SMc03153 -0.9 -3.8 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase compare
SMc02793 -0.9 -4.3 hypothetical protein compare
SMc03060 -0.9 -4.7 transcriptional regulator compare
SMc00321 -0.9 -4.2 tRNA pseudouridine synthase B compare
SMc00492 -0.9 -0.9 hypothetical protein compare
SMc03140 -0.9 -3.5 transcriptional regulator compare
SMc02363 -0.9 -2.3 cytochrome C-type biogenesis transmembrane protein compare
SM_b20105 -0.9 -1.5 transcriptional regulator compare
SMc01842 -0.8 -0.9 methyltransferase transcription regulator protein compare
SMa0789 -0.8 -2.6 GntR family transcriptional regulator compare
SMc02309 -0.8 -4.5 arsenate reductase compare
SM_b20746 -0.8 -1.0 hypothetical protein compare
SMc01845 -0.8 -1.8 transglycosylase transmembrane protein compare
SMc03839 -0.8 -1.2 hypothetical protein compare


Specific Phenotypes

For 5 genes in this experiment

For carbon source D-Sorbitol in Sinorhizobium meliloti 1021

For carbon source D-Sorbitol across organisms