Experiment set1IT020 for Pseudomonas fluorescens FW300-N2E2

Compare to:

Tween 20 carbon source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_64 -7.4 -5.1 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_4825 -6.5 -8.9 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_4077 -6.5 -4.5 cytosolic long-chain acyl-CoA thioester hydrolase family protein compare
Pf6N2E2_71 -6.4 -7.6 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_5006 -6.4 -10.6 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_4597 -6.2 -11.9 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_4596 -6.1 -11.8 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_4826 -6.1 -8.4 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_3060 -6.0 -3.9 Outer membrane protein H precursor compare
Pf6N2E2_3839 -6.0 -5.8 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_77 -5.7 -6.8 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_1381 -5.6 -10.7 Aldehyde dehydrogenase (EC 1.2.1.3) compare
Pf6N2E2_5175 -5.6 -18.5 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_4048 -5.5 -10.5 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_3253 -5.3 -8.0 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_3783 -5.2 -7.9 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_3751 -5.2 -18.0 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_4047 -5.1 -7.8 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_5177 -5.0 -13.8 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_2258 -5.0 -15.0 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_5156 -4.7 -3.2 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_5176 -4.6 -12.3 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_3630 -4.6 -7.5 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_4752 -4.4 -14.8 Malate synthase G (EC 2.3.3.9) compare
Pf6N2E2_279 -4.4 -11.9 Isocitrate lyase (EC 4.1.3.1) compare
Pf6N2E2_3752 -4.3 -19.3 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_4564 -4.3 -8.9 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_2073 -4.3 -10.9 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_2753 -4.2 -5.7 HtrA protease/chaperone protein compare
Pf6N2E2_3782 -4.1 -6.1 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_3258 -3.8 -8.4 Uncharacterized ABC transporter, periplasmic component YrbD compare
Pf6N2E2_2277 -3.8 -4.3 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_3842 -3.7 -4.7 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_1400 -3.7 -12.9 Sensory box histidine kinase/response regulator compare
Pf6N2E2_3932 -3.7 -5.9 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_302 -3.7 -8.0 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_2872 -3.6 -14.9 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) compare
Pf6N2E2_5780 -3.5 -12.4 Periplasmic protease compare
Pf6N2E2_3252 -3.5 -8.2 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_3841 -3.4 -7.0 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_5242 -3.4 -3.3 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_63 -3.4 -6.9 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_3940 -3.4 -11.2 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_1402 -3.4 -8.4 hypothetical protein compare
Pf6N2E2_3661 -3.3 -7.4 hypothetical protein compare
Pf6N2E2_66 -3.3 -7.5 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_2074 -3.2 -3.5 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_3610 -3.2 -3.3 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_5723 -3.2 -11.7 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
Pf6N2E2_605 -3.1 -4.7 FIG002465: BNR repeat protein compare
Pf6N2E2_4638 -3.1 -5.2 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_3248 -3.1 -7.4 Probable transmembrane protein compare
Pf6N2E2_3242 -3.0 -16.2 FIG002188: hypothetical protein conserved
Pf6N2E2_4071 -3.0 -7.4 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_4759 -2.9 -14.2 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_606 -2.8 -11.6 FIG005548: transport protein conserved
Pf6N2E2_5699 -2.8 -9.4 Transcriptional regulatory protein RstA conserved
Pf6N2E2_5579 -2.8 -7.3 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_2261 -2.8 -10.8 VacJ-like lipoprotein precursor compare
Pf6N2E2_5700 -2.8 -12.2 Sensor histidine kinase conserved
Pf6N2E2_3170 -2.7 -6.9 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_2217 -2.7 -8.7 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_2465 -2.7 -6.1 Cys regulon transcriptional activator CysB compare
Pf6N2E2_1932 -2.7 -6.6 Transcriptional regulator, IclR family compare
Pf6N2E2_4766 -2.6 -12.1 Acyl-CoA dehydrogenase (EC 1.3.8.7) conserved
Pf6N2E2_3243 -2.6 -14.1 FIG067310: hypothetical protein conserved
Pf6N2E2_3460 -2.5 -2.7 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_50 -2.5 -8.8 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_3241 -2.5 -9.4 Transcriptional regulator, LuxR family conserved
Pf6N2E2_4372 -2.5 -6.8 FIG00460773: hypothetical protein compare
Pf6N2E2_5553 -2.5 -6.1 Quinolinate synthetase (EC 2.5.1.72) compare
Pf6N2E2_3257 -2.4 -5.9 Uncharacterized ABC transporter, auxiliary component YrbC compare
Pf6N2E2_5527 -2.4 -3.7 Cold shock protein CspC compare
Pf6N2E2_4278 -2.4 -12.5 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_3260 -2.4 -8.7 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
Pf6N2E2_280 -2.3 -3.7 hypothetical protein compare
Pf6N2E2_3346 -2.3 -8.9 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf6N2E2_3659 -2.3 -6.9 Protein fixF compare
Pf6N2E2_5754 -2.3 -10.9 Long-chain fatty acid transport protein conserved
Pf6N2E2_4279 -2.2 -11.6 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_4611 -2.1 -3.6 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_1401 -2.1 -5.5 FIG00955631: hypothetical protein compare
Pf6N2E2_2752 -2.0 -9.5 Exported zinc metalloprotease YfgC precursor compare
Pf6N2E2_4362 -2.0 -4.9 DNA-directed RNA polymerase omega subunit (EC 2.7.7.6) compare
Pf6N2E2_3762 -1.9 -6.4 NADP-dependent malic enzyme (EC 1.1.1.40) compare
Pf6N2E2_3984 -1.9 -10.9 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_4453 -1.9 -13.0 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_2507 -1.9 -4.5 Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-) compare
Pf6N2E2_2335 -1.9 -5.6 Transcriptional regulator, GntR family compare
Pf6N2E2_5728 -1.8 -3.9 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_5727 -1.8 -5.4 FIG00955360: hypothetical protein compare
Pf6N2E2_5160 -1.8 -2.0 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_3251 -1.8 -9.9 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_1056 -1.7 -1.4 Quinone oxidoreductase (EC 1.6.5.5) compare
Pf6N2E2_2574 -1.7 -3.2 Flagellar synthesis regulator FleN compare
Pf6N2E2_2758 -1.7 -10.7 L-aspartate oxidase (EC 1.4.3.16) compare
Pf6N2E2_6140 -1.7 -1.7 Large Subunit Ribosomal RNA; lsuRNA; LSU rRNA compare
Pf6N2E2_3835 -1.7 -6.5 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf6N2E2_3062 -1.6 -5.1 Membrane-associated zinc metalloprotease compare
Pf6N2E2_4769 -1.6 -13.1 Acyl-CoA dehydrogenase (EC 1.3.8.7) conserved
Pf6N2E2_2696 -1.6 -9.7 Isocitrate dehydrogenase phosphatase (EC 2.7.11.5)/kinase (EC 3.1.3.-) conserved
Pf6N2E2_4989 -1.6 -5.3 LrgA-associated membrane protein LrgB conserved
Pf6N2E2_2508 -1.6 -4.0 hypothetical protein compare
Pf6N2E2_5255 -1.6 -9.6 Outer membrane stress sensor protease DegS compare
Pf6N2E2_4277 -1.5 -8.3 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_4352 -1.5 -3.7 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf6N2E2_3349 -1.5 -2.3 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_4009 -1.5 -8.7 GGDEF domain protein compare
Pf6N2E2_4988 -1.4 -4.0 Antiholin-like protein LrgA compare
Pf6N2E2_2526 -1.4 -4.5 Similar to phosphoglycolate phosphatase, clustered with ubiquinone biosynthesis SAM-dependent O-methyltransferase compare
Pf6N2E2_4803 -1.4 -2.1 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_2218 -1.4 -4.8 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_4764 -1.4 -6.5 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_5219 -1.4 -6.3 FIG140336: TPR domain protein compare
Pf6N2E2_5316 -1.3 -1.6 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_5771 -1.3 -6.2 FKBP-type peptidyl-prolyl cis-trans isomerase FklB (EC 5.2.1.8) compare
Pf6N2E2_2756 -1.3 -5.5 RNA polymerase sigma-H factor AlgT compare
Pf6N2E2_5103 -1.3 -1.8 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
Pf6N2E2_5328 -1.3 -5.1 FIG00958649: hypothetical protein compare
Pf6N2E2_5014 -1.3 -1.6 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_2586 -1.3 -2.0 Hpt domain protein compare
Pf6N2E2_4987 -1.2 -1.5 MaoC-like domain protein compare
Pf6N2E2_3461 -1.2 -1.5 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_1116 -1.2 -2.0 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) compare
Pf6N2E2_5943 -1.2 -2.6 hypothetical protein compare
Pf6N2E2_2640 -1.2 -2.8 Permease of the drug/metabolite transporter (DMT) superfamily compare
Pf6N2E2_2912 -1.1 -1.7 FIG00954094: hypothetical protein compare
Pf6N2E2_4761 -1.1 -7.9 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf6N2E2_623 -1.1 -1.6 FIG00954674: hypothetical protein compare
Pf6N2E2_5430 -1.1 -7.0 Transglycosylase, Slt family compare
Pf6N2E2_75 -1.1 -4.1 Colicin V production protein compare
Pf6N2E2_4414 -1.1 -2.6 FIG00953808: hypothetical protein compare
Pf6N2E2_3663 -1.1 -4.4 Glycosyl transferase compare
Pf6N2E2_5739 -1.0 -1.8 Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family compare
Pf6N2E2_178 -1.0 -1.3 Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) compare
Pf6N2E2_4763 -1.0 -6.1 Biotin synthesis protein BioC compare
Pf6N2E2_5794 -1.0 -2.6 Ribosomal large subunit pseudouridine synthase A (EC 4.2.1.70) compare
Pf6N2E2_4631 -1.0 -6.4 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf6N2E2_2022 -1.0 -5.3 BarA-associated response regulator UvrY (= GacA = SirA) compare
Pf6N2E2_622 -1.0 -3.6 BatA (Bacteroides aerotolerance operon) compare
Pf6N2E2_3833 -1.0 -4.0 hypothetical protein compare
Pf6N2E2_3516 -1.0 -2.8 Probable transmembrane protein compare
Pf6N2E2_4928 -1.0 -2.0 Permeases of the major facilitator superfamily compare
Pf6N2E2_5720 -1.0 -8.1 BarA sensory histidine kinase (= VarS = GacS) compare
Pf6N2E2_4810 -1.0 -4.4 Glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) compare
Pf6N2E2_2693 -1.0 -1.9 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.180) compare
Pf6N2E2_2088 -1.0 -1.4 SOS-response repressor and protease LexA (EC 3.4.21.88) compare
Pf6N2E2_2080 -1.0 -1.4 hypothetical protein compare
Pf6N2E2_3899 -0.9 -5.4 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) compare
Pf6N2E2_4075 -0.9 -2.8 Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1) compare
Pf6N2E2_5919 -0.9 -1.8 Flp pilus assembly protein TadD, contains TPR repeats compare
Pf6N2E2_2119 -0.9 -3.3 hypothetical protein compare
Pf6N2E2_2487 -0.9 -1.2 FIG00956090: hypothetical protein compare
Pf6N2E2_4305 -0.9 -1.4 FIG00959590: hypothetical protein compare
Pf6N2E2_1385 -0.9 -2.0 FIG00956261: hypothetical protein compare
Pf6N2E2_5950 -0.9 -3.0 Phosphate:acyl-ACP acyltransferase PlsX compare
Pf6N2E2_624 -0.9 -4.3 hypothetical protein PA3071 compare
Pf6N2E2_2984 -0.9 -1.7 LysR family transcriptional regulator PA3398 compare
Pf6N2E2_3192 -0.9 -3.2 tRNA:Cm32/Um32 methyltransferase compare
Pf6N2E2_621 -0.9 -5.2 TPR domain protein in aerotolerance operon compare
Pf6N2E2_1705 -0.9 -1.7 Branched-chain amino acid transport ATP-binding protein LivG (TC 3.A.1.4.1) compare
Pf6N2E2_4351 -0.9 -6.0 Predicted signal transduction protein compare
Pf6N2E2_1490 -0.8 -1.5 hypothetical protein compare
Pf6N2E2_1870 -0.8 -2.6 hypothetical protein compare
Pf6N2E2_384 -0.8 -2.4 Glycine cleavage system transcriptional activator compare
Pf6N2E2_620 -0.8 -4.5 BatD compare
Pf6N2E2_2156 -0.8 -2.5 Putative polyketide synthase (Fragment) compare
Pf6N2E2_2716 -0.8 -2.8 FIG00954793: hypothetical protein compare
Pf6N2E2_5756 -0.8 -3.2 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_3613 -0.8 -4.6 GTP-binding protein HflX compare
Pf6N2E2_1740 -0.8 -3.1 Transketolase, C-terminal section (EC 2.2.1.1) compare
Pf6N2E2_2274 -0.8 -3.4 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) compare
Pf6N2E2_6058 -0.8 -3.8 FIG139976: hypothetical protein compare
Pf6N2E2_723 -0.8 -3.1 FIG138517: Putative lipid carrier protein compare
Pf6N2E2_3100 -0.8 -1.7 FIG00953063: hypothetical protein compare
Pf6N2E2_613 -0.8 -1.5 lipoprotein, putative compare
Pf6N2E2_4824 -0.8 -1.8 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
Pf6N2E2_4072 -0.8 -2.3 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
Pf6N2E2_4797 -0.7 -1.3 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_2320 -0.7 -2.6 Heavy-metal-associated domain (N-terminus) and membrane-bounded cytochrome biogenesis cycZ-like domain, possible membrane copper tolerance protein compare
Pf6N2E2_5936 -0.7 -1.6 Low molecular weight protein tyrosine phosphatase (EC 3.1.3.48) compare
Pf6N2E2_2010 -0.7 -1.2 hypothetical protein compare
Pf6N2E2_6059 -0.7 -3.1 FIG008443: hypothetical protein compare
Pf6N2E2_319 -0.7 -2.3 DUF1850 domain-containing protein compare
Pf6N2E2_1211 -0.7 -1.0 Lactoylglutathione lyase compare
Pf6N2E2_942 -0.7 -1.5 Mll6465 protein compare
Pf6N2E2_65 -0.7 -3.2 SAM-dependent methyltransferase YafE (UbiE paralog) compare
Pf6N2E2_3901 -0.7 -2.2 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) compare
Pf6N2E2_5252 -0.7 -1.7 FIG00956396: hypothetical protein compare
Pf6N2E2_5584 -0.7 -2.4 Bacterioferritin-associated ferredoxin compare
Pf6N2E2_659 -0.7 -2.0 Transcriptional regulatory protein ompR compare
Pf6N2E2_4478 -0.7 -4.2 FIG019278: hypothetical protein compare
Pf6N2E2_1371 -0.7 -2.1 hypothetical protein compare
Pf6N2E2_282 -0.7 -1.2 GNAT family acetyltransferase YjcF compare
Pf6N2E2_5613 -0.7 -1.2 FIG00953674: hypothetical protein compare
Pf6N2E2_4427 -0.7 -1.1 FIG00954215: hypothetical protein compare
Pf6N2E2_4359 -0.7 -1.9 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_5663 -0.7 -2.7 L-Arginine ABC transporter, ATPase component (from data) compare
Pf6N2E2_5848 -0.7 -2.5 small component of pyruvate transporter (yjcH-like) (from data) compare
Pf6N2E2_754 -0.7 -1.2 Histone acetyltransferase HPA2 and related acetyltransferases compare


Specific Phenotypes

For 12 genes in this experiment

For carbon source Tween 20 in Pseudomonas fluorescens FW300-N2E2

For carbon source Tween 20 across organisms