Experiment set1IT019 for Pseudomonas fluorescens FW300-N2E2

Compare to:

D-Sorbitol carbon source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_4597 -7.5 -5.2 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_3842 -7.0 -4.8 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_4826 -6.9 -6.7 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_77 -6.8 -4.7 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_3630 -6.3 -7.5 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_3839 -6.2 -4.3 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_5176 -6.2 -8.5 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_4596 -6.2 -11.9 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_4206 -6.1 -4.1 Chromosome (plasmid) partitioning protein ParB compare
Pf6N2E2_5006 -6.0 -10.8 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_64 -5.9 -4.9 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_3783 -5.9 -7.0 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_71 -5.8 -7.9 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_3253 -5.5 -8.4 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_4047 -5.5 -5.4 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_5175 -5.4 -17.9 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_3751 -5.3 -15.7 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_2885 -5.2 -7.1 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) compare
Pf6N2E2_5177 -5.2 -12.3 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_3752 -5.1 -23.7 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_4825 -5.1 -9.9 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_1961 -5.0 -10.2 ABC transporter for D-sorbitol, permease component 2 (from data) conserved
Pf6N2E2_4279 -5.0 -14.6 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_3841 -4.9 -7.5 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_3782 -4.7 -5.4 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_4564 -4.6 -9.8 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_302 -4.6 -9.1 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_2074 -4.5 -2.5 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_3940 -4.5 -11.3 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_1960 -4.4 -8.1 ABC transporter for D-sorbitol, ATPase component (from data) conserved
Pf6N2E2_3252 -4.4 -9.4 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_4048 -4.4 -7.3 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_4762 -4.4 -3.7 Biotin synthesis protein BioH compare
Pf6N2E2_2753 -4.4 -5.2 HtrA protease/chaperone protein compare
Pf6N2E2_1963 -4.4 -13.0 ABC transporter for D-sorbitol, periplasmic substrate-binding component (from data) conserved
Pf6N2E2_66 -4.3 -9.6 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_5150 -4.3 -8.2 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf6N2E2_2073 -4.2 -10.0 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_3932 -4.1 -5.1 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_4803 -4.1 -2.8 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_3248 -4.0 -4.4 Probable transmembrane protein compare
Pf6N2E2_4759 -3.9 -16.0 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_4638 -3.9 -5.3 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_1965 -3.8 -10.0 Fructokinase (EC 2.7.1.4) (from data) conserved
Pf6N2E2_4278 -3.7 -11.2 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_4077 -3.6 -2.9 cytosolic long-chain acyl-CoA thioester hydrolase family protein compare
Pf6N2E2_1959 -3.3 -5.0 D-sorbitol dehydrogenase (EC 1.1.1.14) (from data) compare
Pf6N2E2_5001 -3.2 -2.9 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) compare
Pf6N2E2_5156 -3.1 -4.7 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_4277 -3.1 -9.8 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_2218 -3.0 -6.0 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_3610 -3.0 -3.1 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_63 -3.0 -4.7 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_1381 -3.0 -8.6 Aldehyde dehydrogenase (EC 1.2.1.3) compare
Pf6N2E2_2217 -3.0 -8.0 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_4763 -2.9 -10.4 Biotin synthesis protein BioC compare
Pf6N2E2_3251 -2.8 -9.4 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_4416 -2.7 -3.8 Tyrosine recombinase XerC compare
Pf6N2E2_2258 -2.6 -9.4 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_5252 -2.6 -2.1 FIG00956396: hypothetical protein compare
Pf6N2E2_4761 -2.6 -9.5 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf6N2E2_3170 -2.6 -6.3 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_50 -2.5 -5.8 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_3460 -2.5 -2.9 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_4071 -2.4 -4.3 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_2465 -2.4 -4.9 Cys regulon transcriptional activator CysB compare
Pf6N2E2_5316 -2.4 -2.1 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_5780 -2.3 -9.8 Periplasmic protease compare
Pf6N2E2_5579 -2.3 -5.3 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_4631 -2.3 -7.9 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf6N2E2_4733 -2.3 -2.3 hypothetical protein compare
Pf6N2E2_4372 -2.2 -5.4 FIG00460773: hypothetical protein compare
Pf6N2E2_1400 -2.1 -12.3 Sensory box histidine kinase/response regulator compare
Pf6N2E2_5728 -2.1 -4.9 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_4764 -1.9 -4.7 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_2010 -1.9 -2.5 hypothetical protein compare
Pf6N2E2_3984 -1.9 -8.8 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_5160 -1.9 -1.9 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_5536 -1.8 -2.3 Holliday junction DNA helicase RuvA compare
Pf6N2E2_2274 -1.8 -4.4 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) compare
Pf6N2E2_1932 -1.7 -5.9 Transcriptional regulator, IclR family compare
Pf6N2E2_5676 -1.7 -3.3 Aspartokinase (EC 2.7.2.4) compare
Pf6N2E2_5553 -1.7 -5.8 Quinolinate synthetase (EC 2.5.1.72) compare
Pf6N2E2_2693 -1.7 -2.0 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.180) compare
Pf6N2E2_4187 -1.7 -4.2 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_2514 -1.7 -4.8 regulator of length of O-antigen component of lipopolysaccharide chains compare
Pf6N2E2_2012 -1.7 -2.3 hypothetical protein compare
Pf6N2E2_5666 -1.7 -7.7 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_5527 -1.6 -2.4 Cold shock protein CspC compare
Pf6N2E2_2473 -1.6 -1.7 Major outer membrane lipoprotein I compare
Pf6N2E2_2899 -1.6 -3.7 NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) compare
Pf6N2E2_4009 -1.6 -8.6 GGDEF domain protein compare
Pf6N2E2_3835 -1.5 -5.8 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf6N2E2_5014 -1.5 -1.5 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_3346 -1.4 -3.5 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf6N2E2_5739 -1.4 -1.7 Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family compare
Pf6N2E2_4417 -1.4 -3.4 Protein of unknown function DUF484 compare
Pf6N2E2_3938 -1.4 -8.3 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf6N2E2_3271 -1.4 -2.6 Phosphocarrier protein, nitrogen regulation associated compare
Pf6N2E2_5243 -1.3 -1.9 hypothetical protein compare
Pf6N2E2_1402 -1.3 -5.7 hypothetical protein compare
Pf6N2E2_5943 -1.3 -1.6 hypothetical protein compare
Pf6N2E2_3349 -1.3 -1.5 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_2479 -1.3 -2.0 Transcription elongation factor GreB compare
Pf6N2E2_2574 -1.3 -1.9 Flagellar synthesis regulator FleN compare
Pf6N2E2_1718 -1.2 -2.5 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) compare
Pf6N2E2_2106 -1.2 -1.8 hypothetical protein compare
Pf6N2E2_1136 -1.2 -2.7 Transcriptional regulator, TetR family compare
Pf6N2E2_248 -1.2 -4.4 hypothetical protein compare
Pf6N2E2_178 -1.2 -1.1 Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) compare
Pf6N2E2_3039 -1.2 -4.8 Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) compare
Pf6N2E2_5219 -1.2 -6.3 FIG140336: TPR domain protein compare
Pf6N2E2_2065 -1.1 -3.9 Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) compare
Pf6N2E2_4205 -1.1 -2.9 Chromosome (plasmid) partitioning protein ParA compare
Pf6N2E2_288 -1.1 -2.4 Isocitrate dehydrogenase [NADP] (EC 1.1.1.42); Monomeric isocitrate dehydrogenase [NADP] (EC 1.1.1.42) compare
Pf6N2E2_4969 -1.1 -1.2 hypothetical protein compare
Pf6N2E2_4678 -1.1 -1.0 hypothetical protein compare
Pf6N2E2_2320 -1.1 -2.7 Heavy-metal-associated domain (N-terminus) and membrane-bounded cytochrome biogenesis cycZ-like domain, possible membrane copper tolerance protein compare
Pf6N2E2_5841 -1.1 -1.3 GlcG protein compare
Pf6N2E2_4352 -1.1 -2.2 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf6N2E2_3778 -1.1 -3.2 FIG00954300: hypothetical protein compare
Pf6N2E2_3825 -1.1 -4.3 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
Pf6N2E2_2480 -1.1 -1.7 FIG00957636: hypothetical protein compare
Pf6N2E2_4640 -1.1 -1.6 hypothetical protein compare
Pf6N2E2_75 -1.1 -2.5 Colicin V production protein compare
Pf6N2E2_4049 -1.1 -5.3 Glycine cleavage system transcriptional activator compare
Pf6N2E2_5155 -1.1 -2.4 Poly(A) polymerase (EC 2.7.7.19) compare
Pf6N2E2_2121 -1.1 -2.1 hypothetical protein compare
Pf6N2E2_3095 -1.1 -1.2 hypothetical protein compare
Pf6N2E2_3338 -1.1 -1.4 1-phosphofructokinase (EC 2.7.1.56) compare
Pf6N2E2_1352 -1.0 -2.2 Cation transport ATPase compare
Pf6N2E2_2758 -1.0 -7.2 L-aspartate oxidase (EC 1.4.3.16) compare
Pf6N2E2_2752 -1.0 -5.0 Exported zinc metalloprotease YfgC precursor compare
Pf6N2E2_3461 -1.0 -1.5 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_127 -1.0 -1.1 AttE component of AttEFGH ABC transport system compare
Pf6N2E2_3786 -1.0 -2.1 Twin-arginine translocation protein TatC compare
Pf6N2E2_5667 -1.0 -4.4 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_3351 -1.0 -3.3 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
Pf6N2E2_809 -1.0 -2.7 Various polyols ABC transporter, permease component 1 compare
Pf6N2E2_5714 -1.0 -2.1 Flavoprotein WrbA compare
Pf6N2E2_2072 -1.0 -1.9 hypothetical protein compare
Pf6N2E2_3072 -0.9 -5.6 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
Pf6N2E2_4797 -0.9 -0.8 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_2707 -0.9 -3.7 Allophanate hydrolase 2 subunit 1 (EC 3.5.1.54) compare
Pf6N2E2_5258 -0.9 -4.4 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_3249 -0.9 -4.7 Zn-dependent protease with chaperone function compare
Pf6N2E2_3062 -0.9 -2.6 Membrane-associated zinc metalloprotease compare
Pf6N2E2_5237 -0.9 -0.8 Hypoxanthine-guanine phosphoribosyltransferase (EC 2.4.2.8) compare
Pf6N2E2_377 -0.9 -2.7 hypothetical protein compare
Pf6N2E2_2313 -0.9 -1.7 Cytochrome c oxidase subunit CcoP (EC 1.9.3.1) compare
Pf6N2E2_3325 -0.9 -2.2 ABC transporter, ATP-binding protein compare
Pf6N2E2_2588 -0.9 -2.3 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV compare
Pf6N2E2_5671 -0.9 -2.6 Succinylglutamate desuccinylase (EC 3.5.1.96) compare
Pf6N2E2_3941 -0.9 -1.4 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf6N2E2_3571 -0.9 -2.1 Urease accessory protein UreF compare
Pf6N2E2_4204 -0.9 -1.3 rRNA small subunit 7-methylguanosine (m7G) methyltransferase GidB compare
Pf6N2E2_1964 -0.9 -3.0 Transcriptional regulator of various polyols utilization, AraC family compare
Pf6N2E2_1189 -0.9 -3.6 Thioredoxin reductase (EC 1.8.1.9) compare
Pf6N2E2_5338 -0.9 -4.5 Ubiquinol--cytochrome c reductase, cytochrome B subunit (EC 1.10.2.2) compare
Pf6N2E2_1081 -0.9 -1.2 probable membrane protein YPO3302 compare
Pf6N2E2_623 -0.9 -1.1 FIG00954674: hypothetical protein compare
Pf6N2E2_3763 -0.9 -1.1 hypothetical protein compare
Pf6N2E2_2261 -0.8 -3.9 VacJ-like lipoprotein precursor compare
Pf6N2E2_2756 -0.8 -3.5 RNA polymerase sigma-H factor AlgT compare
Pf6N2E2_1169 -0.8 -1.9 TnpR protein compare
Pf6N2E2_3021 -0.8 -1.1 hypothetical protein compare
Pf6N2E2_65 -0.8 -4.0 SAM-dependent methyltransferase YafE (UbiE paralog) compare
Pf6N2E2_5768 -0.8 -3.2 DNA recombination-dependent growth factor C compare
Pf6N2E2_5190 -0.8 -4.8 Carbonic anhydrase (EC 4.2.1.1) compare
Pf6N2E2_1040 -0.8 -1.1 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
Pf6N2E2_1717 -0.8 -4.9 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
Pf6N2E2_5339 -0.8 -3.7 ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit compare
Pf6N2E2_1173 -0.8 -1.7 hypothetical protein compare
Pf6N2E2_3533 -0.8 -3.5 Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) compare
Pf6N2E2_4072 -0.8 -3.0 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
Pf6N2E2_2973 -0.8 -2.4 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_453 -0.8 -2.0 LysR family transcriptional regulator STM2281 compare
Pf6N2E2_4601 -0.8 -1.3 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC compare
Pf6N2E2_4984 -0.8 -2.2 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_4159 -0.8 -3.1 Cytochrome c4 compare
Pf6N2E2_2442 -0.8 -5.2 sensor histidine kinase/response regulator compare
Pf6N2E2_2681 -0.8 -2.8 3-phosphoglycerate kinase compare
Pf6N2E2_6065 -0.8 -1.5 ABC transporter in pyoverdin gene cluster, periplasmic component compare
Pf6N2E2_2317 -0.8 -2.7 Putative analog of CcoH, COG3198 compare
Pf6N2E2_5955 -0.8 -2.5 Aminodeoxychorismate lyase (EC 4.1.3.38) compare
Pf6N2E2_2472 -0.8 -1.7 hypothetical protein compare
Pf6N2E2_3661 -0.8 -2.2 hypothetical protein compare
Pf6N2E2_3770 -0.8 -1.7 ATP-dependent hsl protease ATP-binding subunit HslU compare
Pf6N2E2_1095 -0.8 -1.6 Opine oxidase subunit C compare
Pf6N2E2_1128 -0.8 -1.0 Two-component response regulator compare
Pf6N2E2_5820 -0.8 -2.3 FIG00957914: hypothetical protein compare
Pf6N2E2_2852 -0.8 -4.2 GGDEF domain/EAL domain protein compare
Pf6N2E2_2488 -0.7 -1.2 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_3611 -0.7 -1.3 HflC protein compare
Pf6N2E2_3060 -0.7 -1.7 Outer membrane protein H precursor compare
Pf6N2E2_3328 -0.7 -1.7 transcriptional regulator compare
Pf6N2E2_2880 -0.7 -2.2 FIG00959696: hypothetical protein compare
Pf6N2E2_5990 -0.7 -1.1 Translation initiation factor 2 (IF-2; GTPase) compare
Pf6N2E2_807 -0.7 -3.9 Various polyols ABC transporter, ATP-binding component compare
Pf6N2E2_319 -0.7 -2.4 DUF1850 domain-containing protein compare


Specific Phenotypes

For 5 genes in this experiment

For carbon source D-Sorbitol in Pseudomonas fluorescens FW300-N2E2

For carbon source D-Sorbitol across organisms