Experiment set1IT019 for Pseudomonas fluorescens FW300-N2E2

Compare to:

D-Sorbitol carbon source

200 most detrimental genes:

  gene name fitness t score description  
Pf6N2E2_5720 +2.3 18.6 BarA sensory histidine kinase (= VarS = GacS) compare
Pf6N2E2_2755 +2.0 3.3 Sigma factor RpoE negative regulatory protein RseA compare
Pf6N2E2_2057 +2.0 14.3 Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipi n synthases and related enzymes compare
Pf6N2E2_2022 +1.9 11.9 BarA-associated response regulator UvrY (= GacA = SirA) compare
Pf6N2E2_1981 +1.9 4.9 FIG051360: Periplasmic protein TonB, links inner and outer membranes compare
Pf6N2E2_4153 +1.8 3.8 Sensory box histidine kinase compare
Pf6N2E2_6057 +1.7 7.2 FIG002781: Alpha-L-glutamate ligase family protein compare
Pf6N2E2_1056 +1.3 1.4 Quinone oxidoreductase (EC 1.6.5.5) compare
Pf6N2E2_1391 +1.2 3.4 DNA-binding response regulator, LuxR family compare
Pf6N2E2_2675 +1.2 1.8 ATP-dependent RNA helicase SrmB compare
Pf6N2E2_6058 +1.2 5.9 FIG139976: hypothetical protein compare
Pf6N2E2_5178 +1.1 2.6 CDP-diacylglycerol--serine O-phosphatidyltransferase (EC 2.7.8.8) compare
Pf6N2E2_2594 +1.1 6.1 Flagellar hook-basal body complex protein FliE compare
Pf6N2E2_4773 +1.1 1.7 Coenzyme PQQ synthesis protein D compare
Pf6N2E2_3792 +1.1 6.8 Glucans biosynthesis protein G precursor compare
Pf6N2E2_2582 +1.1 2.5 Flagellar motor switch protein FliN compare
Pf6N2E2_2825 +1.0 4.5 RND efflux system, outer membrane lipoprotein CmeC compare
Pf6N2E2_2628 +1.0 5.0 Flagellar basal-body rod protein FlgF compare
Pf6N2E2_2124 +1.0 1.8 Mg(2+) transport ATPase protein C compare
Pf6N2E2_4340 +1.0 4.2 Outer membrane protein ImpK/VasF, OmpA/MotB domain compare
Pf6N2E2_3981 +1.0 8.8 T1SS secreted agglutinin RTX compare
Pf6N2E2_3791 +1.0 6.9 Glucans biosynthesis glucosyltransferase H (EC 2.4.1.-) compare
Pf6N2E2_3033 +1.0 1.6 hypothetical protein compare
Pf6N2E2_2152 +1.0 2.3 hypothetical protein compare
Pf6N2E2_3978 +1.0 6.9 Type I secretion system, membrane fusion protein LapC compare
Pf6N2E2_1625 +1.0 2.4 Ferric reductase (1.6.99.14) compare
Pf6N2E2_2440 +0.9 1.5 Free methionine-(R)-sulfoxide reductase, contains GAF domain compare
Pf6N2E2_4334 +0.9 6.4 Uncharacterized protein ImpC compare
Pf6N2E2_3206 +0.9 2.1 hypothetical protein compare
Pf6N2E2_3979 +0.9 7.4 Type I secretion system ATPase, LssB family LapB compare
Pf6N2E2_2284 +0.9 1.1 Cell division inhibitor-related protein compare
Pf6N2E2_3663 +0.9 4.7 Glycosyl transferase compare
Pf6N2E2_629 +0.9 2.6 2-ketogluconate kinase (EC 2.7.1.13) compare
Pf6N2E2_2577 +0.9 5.8 Flagellar biosynthesis protein FlhB compare
Pf6N2E2_2592 +0.9 4.6 Flagellar motor switch protein FliG compare
Pf6N2E2_5677 +0.9 1.4 Carbon storage regulator compare
Pf6N2E2_1860 +0.9 2.8 Ferredoxin, 2Fe-2S compare
Pf6N2E2_5694 +0.9 4.6 Flagellar basal-body rod protein FlgB compare
Pf6N2E2_5695 +0.9 6.1 Flagellar basal-body rod protein FlgC compare
Pf6N2E2_1596 +0.9 1.9 Periplasmic nitrate reductase component NapD compare
Pf6N2E2_2590 +0.9 6.6 Flagellum-specific ATP synthase FliI compare
Pf6N2E2_3969 +0.8 1.1 Membrane-fusion protein compare
Pf6N2E2_4339 +0.8 6.4 Uncharacterized protein ImpJ/VasE compare
Pf6N2E2_2178 +0.8 4.2 FIG00960144: hypothetical protein compare
Pf6N2E2_572 +0.8 3.1 hypothetical protein compare
Pf6N2E2_2597 +0.8 6.1 Flagellar regulatory protein FleQ compare
Pf6N2E2_5906 +0.8 2.7 Flp pilus assembly protein, pilin Flp compare
Pf6N2E2_2583 +0.8 4.7 Flagellar motor switch protein FliM compare
Pf6N2E2_2627 +0.8 3.6 Flagellar basal-body rod protein FlgG compare
Pf6N2E2_987 +0.8 1.8 hypothetical protein compare
Pf6N2E2_4418 +0.8 1.0 Diaminopimelate epimerase (EC 5.1.1.7) compare
Pf6N2E2_4335 +0.8 5.4 Uncharacterized protein ImpB compare
Pf6N2E2_4612 +0.8 4.1 Glutathione synthetase (EC 6.3.2.3) compare
Pf6N2E2_114 +0.8 2.2 Polysaccharide biosynthesis protein compare
Pf6N2E2_2438 +0.8 1.5 hypothetical protein compare
Pf6N2E2_2175 +0.8 3.4 Transcriptional regulator, RpiR family compare
Pf6N2E2_2589 +0.8 3.1 Flagellar protein FliJ compare
Pf6N2E2_445 +0.8 4.6 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) compare
Pf6N2E2_3612 +0.8 2.5 HflK protein compare
Pf6N2E2_828 +0.8 2.6 Transcriptional regulator, TetR family compare
Pf6N2E2_5785 +0.8 1.3 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_2324 +0.8 3.1 Adenine phosphoribosyltransferase (EC 2.4.2.7) compare
Pf6N2E2_2181 +0.7 2.0 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_5134 +0.7 2.2 FIG060329: MOSC domain protein compare
Pf6N2E2_3037 +0.7 5.3 RNA polymerase sigma factor RpoS compare
Pf6N2E2_1896 +0.7 2.3 hypothetical protein compare
Pf6N2E2_4341 +0.7 6.5 IcmF-related protein compare
Pf6N2E2_2576 +0.7 5.8 Flagellar biosynthesis protein FlhA compare
Pf6N2E2_2428 +0.7 1.5 Thiol-disulfide isomerase and thioredoxins compare
Pf6N2E2_2579 +0.7 4.7 Flagellar biosynthesis protein FliQ compare
Pf6N2E2_5697 +0.7 6.1 Flagellar hook protein FlgE compare
Pf6N2E2_2563 +0.7 5.6 FIG00953562: hypothetical protein compare
Pf6N2E2_3664 +0.7 4.8 Carbamoyltransferase in large core OS assembly cluster compare
Pf6N2E2_5609 +0.7 3.5 DNA-binding response regulator ColR compare
Pf6N2E2_2455 +0.7 3.5 FIG00953957: hypothetical protein compare
Pf6N2E2_2585 +0.7 5.3 Flagellar hook-length control protein FliK compare
Pf6N2E2_1379 +0.7 3.5 Sensory box histidine kinase/response regulator compare
Pf6N2E2_1534 +0.7 1.1 Probable transmembrane protein compare
Pf6N2E2_1248 +0.7 2.3 MutT/nudix family protein compare
Pf6N2E2_4743 +0.7 1.0 hypothetical protein compare
Pf6N2E2_4345 +0.7 3.4 ABC transporter, ATP-binding protein compare
Pf6N2E2_1006 +0.7 1.5 Ribose ABC transport system, periplasmic ribose-binding protein RbsB (TC 3.A.1.2.1) compare
Pf6N2E2_1984 +0.7 2.0 probable exported protein STY4558 compare
Pf6N2E2_2055 +0.7 2.2 StbE replicon stabilization toxin compare
Pf6N2E2_5771 +0.7 3.8 FKBP-type peptidyl-prolyl cis-trans isomerase FklB (EC 5.2.1.8) compare
Pf6N2E2_367 +0.7 2.1 Acetylornithine deacetylase (EC 3.5.1.16) compare
Pf6N2E2_4054 +0.7 2.1 Osmotically inducible protein C compare
Pf6N2E2_2578 +0.7 2.5 Flagellar biosynthesis protein FliR compare
Pf6N2E2_342 +0.7 1.4 DNA-binding response regulator compare
Pf6N2E2_4337 +0.7 4.7 Uncharacterized protein ImpI/VasC compare
Pf6N2E2_405 +0.7 1.2 hypothetical protein compare
Pf6N2E2_1398 +0.7 2.9 Rhodanese-related sulfurtransferase compare
Pf6N2E2_1673 +0.7 2.4 Transcriptional regulator, TetR family compare
Pf6N2E2_1339 +0.6 1.4 Acetylornithine deacetylase (EC 3.5.1.16) compare
Pf6N2E2_300 +0.6 1.6 CrcB protein compare
Pf6N2E2_3667 +0.6 1.3 Heptose kinase WapQ, eukaryotic type compare
Pf6N2E2_4336 +0.6 4.1 Uncharacterized protein ImpA compare
Pf6N2E2_2278 +0.6 5.2 Transcription-repair coupling factor compare
Pf6N2E2_1755 +0.6 2.4 2-Oxobutyrate oxidase, putative compare
Pf6N2E2_3134 +0.6 0.9 hypothetical protein compare
Pf6N2E2_2312 +0.6 1.6 Cytochrome c oxidase subunit CcoQ (EC 1.9.3.1) compare
Pf6N2E2_4329 +0.6 4.1 Protein ImpG/VasA compare
Pf6N2E2_2823 +0.6 1.8 Multidrug efflux RND membrane fusion protein MexC compare
Pf6N2E2_4263 +0.6 1.8 Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family compare
Pf6N2E2_5874 +0.6 5.3 TonB-dependent receptor; Outer membrane receptor for ferrienterochelin and colicins compare
Pf6N2E2_2222 +0.6 3.1 Murein-DD-endopeptidase (EC 3.4.99.-) compare
Pf6N2E2_2502 +0.6 2.1 O-antigen acetylase compare
Pf6N2E2_3237 +0.6 2.7 hypothetical protein compare
Pf6N2E2_3004 +0.6 2.3 Prophage baseplate assembly protein V compare
Pf6N2E2_945 +0.6 2.1 Transcriptional regulator, TetR family compare
Pf6N2E2_1110 +0.6 1.9 FIG00964414: hypothetical protein compare
Pf6N2E2_4706 +0.6 1.7 Electron transfer flavoprotein, beta subunit compare
Pf6N2E2_923 +0.6 0.9 Haloacid dehalogenase, type II (EC 3.8.1.2) compare
Pf6N2E2_4328 +0.6 4.9 Uncharacterized protein ImpH/VasB compare
Pf6N2E2_4343 +0.6 3.3 Phosphoprotein phosphatase PppA compare
Pf6N2E2_2593 +0.6 3.2 Flagellar M-ring protein FliF compare
Pf6N2E2_5898 +0.6 2.6 Integral membrane protein compare
Pf6N2E2_4148 +0.6 3.4 Glutamate-aspartate carrier protein compare
Pf6N2E2_4658 +0.6 3.4 FIG00955006: hypothetical protein compare
Pf6N2E2_1989 +0.6 2.4 hypothetical protein compare
Pf6N2E2_5508 +0.6 0.9 Formyltetrahydrofolate deformylase (EC 3.5.1.10) compare
Pf6N2E2_3219 +0.6 1.1 hypothetical protein compare
Pf6N2E2_3088 +0.6 1.3 hypothetical protein compare
Pf6N2E2_5696 +0.6 2.9 Flagellar basal-body rod modification protein FlgD compare
Pf6N2E2_2788 +0.6 1.7 Transcriptional regulator, AsnC family compare
Pf6N2E2_69 +0.6 3.7 Probable type IV pilus assembly FimV-related transmembrane protein compare
Pf6N2E2_2835 +0.6 1.8 Beta-ketoadipyl CoA thiolase (EC 2.3.1.-) compare
Pf6N2E2_5845 +0.6 2.7 Nucleoside ABC transporter, periplasmic nucleoside-binding protein compare
Pf6N2E2_2503 +0.6 1.3 Glycosyl transferase, group 1 family protein compare
Pf6N2E2_5078 +0.6 1.8 Carbon starvation protein A compare
Pf6N2E2_1876 +0.6 1.6 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) compare
Pf6N2E2_4988 +0.5 2.0 Antiholin-like protein LrgA compare
Pf6N2E2_4347 +0.5 4.2 FIG00957151: hypothetical protein compare
Pf6N2E2_1032 +0.5 0.8 Alkanesulfonates ABC transporter ATP-binding protein / Sulfonate ABC transporter, ATP-binding subunit SsuB compare
Pf6N2E2_5573 +0.5 2.2 Glycerol-3-phosphate regulon repressor, DeoR family compare
Pf6N2E2_4333 +0.5 3.1 Uncharacterized protein ImpD compare
Pf6N2E2_625 +0.5 2.6 MoxR-like ATPase in aerotolerance operon compare
Pf6N2E2_690 +0.5 1.6 Transcriptional regulator, LysR family compare
Pf6N2E2_5595 +0.5 2.2 Electron transport complex protein RnfE compare
Pf6N2E2_1124 +0.5 1.1 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_4084 +0.5 2.6 Transcriptional regulator compare
Pf6N2E2_4332 +0.5 3.3 hypothetical protein compare
Pf6N2E2_4315 +0.5 4.8 Rhs-family protein compare
Pf6N2E2_3205 +0.5 1.7 Mobile element protein compare
Pf6N2E2_5605 +0.5 1.5 FxsA protein compare
Pf6N2E2_1452 +0.5 1.8 hypothetical protein compare
Pf6N2E2_1443 +0.5 1.6 putative aldo/keto reductase compare
Pf6N2E2_3573 +0.5 1.7 HupE-UreJ family metal transporter compare
Pf6N2E2_5877 +0.5 1.9 Phosphohistidine phosphatase SixA compare
Pf6N2E2_3638 +0.5 1.8 hypothetical protein compare
Pf6N2E2_4729 +0.5 1.6 hypothetical protein compare
Pf6N2E2_5691 +0.5 3.6 Flagellar basal-body P-ring formation protein FlgA compare
Pf6N2E2_4917 +0.5 2.6 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_5283 +0.5 2.5 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) compare
Pf6N2E2_3908 +0.5 3.0 Glutamate--cysteine ligase (EC 6.3.2.2) compare
Pf6N2E2_3634 +0.5 0.9 Transporter compare
Pf6N2E2_4344 +0.5 4.6 Serine/threonine protein kinase (EC 2.7.11.1) PpkA compare
Pf6N2E2_4348 +0.5 3.0 Autotransporter adhesin compare
Pf6N2E2_2625 +0.5 1.7 Flagellar P-ring protein FlgI compare
Pf6N2E2_2176 +0.5 0.8 Amidases related to nicotinamidase compare
Pf6N2E2_1720 +0.5 2.3 hypothetical protein compare
Pf6N2E2_5225 +0.5 4.2 Lipid A 3-O-deacylase compare
Pf6N2E2_2002 +0.5 2.0 hypothetical protein compare
Pf6N2E2_1140 +0.5 2.5 Polymyxin resistance protein ArnC, glycosyl transferase (EC 2.4.-.-) compare
Pf6N2E2_1034 +0.5 1.1 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_2584 +0.5 2.8 Flagellar biosynthesis protein FliL compare
Pf6N2E2_1568 +0.5 2.3 FIG00960890: hypothetical protein compare
Pf6N2E2_600 +0.5 1.0 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases compare
Pf6N2E2_3665 +0.5 0.6 serine/threonine protein kinase compare
Pf6N2E2_1599 +0.5 1.6 Cytochrome c-type protein NapC compare
Pf6N2E2_2080 +0.5 0.9 hypothetical protein compare
Pf6N2E2_591 +0.5 2.6 Streptothricin acetyltransferase, Streptomyces lavendulae type compare
Pf6N2E2_5183 +0.5 4.3 Paraquat-inducible protein B compare
Pf6N2E2_5873 +0.5 2.9 FIG00953467: hypothetical protein compare
Pf6N2E2_2314 +0.5 2.0 VapB protein (antitoxin to VapC) compare
Pf6N2E2_2967 +0.5 1.1 Cold shock protein CspA compare
Pf6N2E2_3980 +0.5 3.7 Type I secretion system, outer membrane component LapE compare
Pf6N2E2_902 +0.5 1.2 hypothetical protein compare
Pf6N2E2_1747 +0.5 1.8 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) compare
Pf6N2E2_5647 +0.5 1.9 Transcriptional regulator, TetR family compare
Pf6N2E2_952 +0.5 2.2 putative exported protein compare
Pf6N2E2_2112 +0.5 2.1 Dehydrocarnitine CoA-transferase and acetoacetate CoA-transferase, subunit B (from data) compare
Pf6N2E2_5394 +0.5 1.3 Molybdenum cofactor biosynthesis protein MoaE compare
Pf6N2E2_5757 +0.5 1.4 hypothetical protein compare
Pf6N2E2_4057 +0.5 0.6 lipoprotein, putative compare
Pf6N2E2_1762 +0.5 1.4 putative lipase compare
Pf6N2E2_1685 +0.5 2.4 Vitamin B12 ABC transporter, B12-binding component BtuF compare
Pf6N2E2_4776 +0.5 3.8 Coenzyme PQQ synthesis protein F compare
Pf6N2E2_2018 +0.5 1.4 hypothetical protein compare
Pf6N2E2_109 +0.5 2.9 Hydrolases of the alpha/beta superfamily compare
Pf6N2E2_3807 +0.5 1.7 Histidine utilization repressor compare
Pf6N2E2_5168 +0.5 2.5 Regulator of competence-specific genes compare
Pf6N2E2_5825 +0.5 1.9 FIG00958237: hypothetical protein compare
Pf6N2E2_3122 +0.5 1.4 Chemotaxis signal transduction protein compare
Pf6N2E2_2602 +0.5 3.0 Flagellin protein FlaA compare
Pf6N2E2_5884 +0.5 3.6 Sensor histidine kinase compare
Pf6N2E2_5786 +0.5 2.7 ABC transporter, ATP-binding protein compare
Pf6N2E2_1504 +0.5 1.3 putative 2-pyrone-4,6-dicarboxylic acid hydrolase compare
Pf6N2E2_350 +0.5 1.1 Gfa-like protein compare
Pf6N2E2_1809 +0.5 2.0 Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1) compare


Specific Phenotypes

For 5 genes in this experiment

For carbon source D-Sorbitol in Pseudomonas fluorescens FW300-N2E2

For carbon source D-Sorbitol across organisms