Experiment set1IT019 for Pseudomonas fluorescens FW300-N1B4

Compare to:

Sodium pyruvate carbon source

200 most important genes:

  gene name fitness t score description  
Pf1N1B4_2272 -3.0 -4.0 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf1N1B4_5665 -3.0 -6.4 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf1N1B4_6 -2.9 -5.7 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf1N1B4_1067 -2.9 -6.8 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf1N1B4_1831 -2.7 -11.4 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf1N1B4_2880 -2.5 -11.6 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf1N1B4_1624 -2.5 -9.4 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf1N1B4_1837 -2.5 -1.7 Osmotically inducible protein C compare
Pf1N1B4_1534 -2.3 -15.6 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf1N1B4_2545 -2.3 -13.1 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
Pf1N1B4_15 -2.3 -4.7 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf1N1B4_3518 -2.3 -3.6 Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) compare
Pf1N1B4_1626 -2.3 -7.2 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf1N1B4_2858 -2.2 -10.3 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf1N1B4_742 -2.2 -8.4 Argininosuccinate synthase (EC 6.3.4.5) compare
Pf1N1B4_1533 -2.2 -8.2 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf1N1B4_4835 -2.2 -3.1 Carbon starvation protein A compare
Pf1N1B4_12 -2.1 -6.9 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf1N1B4_1830 -2.1 -7.9 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf1N1B4_2338 -2.1 -8.4 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf1N1B4_2879 -2.1 -6.9 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf1N1B4_1408 -2.1 -4.2 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf1N1B4_2303 -2.1 -11.9 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf1N1B4_1315 -2.0 -7.4 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) compare
Pf1N1B4_1434 -2.0 -7.5 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf1N1B4_3917 -2.0 -4.5 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf1N1B4_762 -1.9 -6.3 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf1N1B4_847 -1.9 -7.7 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf1N1B4_2878 -1.9 -7.4 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf1N1B4_412 -1.8 -3.2 L-arabinose 1-dehydrogenase / D-galactose 1-dehydrogenase (EC 1.1.1.46; EC 1.1.1.48) (from data) compare
Pf1N1B4_2337 -1.8 -4.8 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf1N1B4_2011 -1.8 -8.1 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf1N1B4_2549 -1.8 -7.8 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf1N1B4_2384 -1.8 -8.1 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf1N1B4_2547 -1.7 -3.4 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
Pf1N1B4_1307 -1.7 -2.2 3-dehydroquinate dehydratase II (EC 4.2.1.10) compare
Pf1N1B4_866 -1.7 -1.9 Iron-sulfur cluster regulator IscR compare
Pf1N1B4_5402 -1.7 -2.5 hypothetical protein compare
Pf1N1B4_1627 -1.7 -4.1 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf1N1B4_2282 -1.7 -7.6 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf1N1B4_350 -1.7 -5.8 Chorismate mutase I (EC 5.4.99.5) / Prephenate dehydratase (EC 4.2.1.51) compare
Pf1N1B4_3812 -1.6 -6.6 Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) compare
Pf1N1B4_1827 -1.6 -4.2 FIG00953482: hypothetical protein compare
Pf1N1B4_2859 -1.6 -11.1 Two-component sensor CbrA: intrcellular carbon:nitrogen balance compare
Pf1N1B4_1057 -1.6 -3.1 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf1N1B4_3673 -1.6 -8.5 large component of pyruvate transporter (actP-like) (from data) conserved
Pf1N1B4_2548 -1.6 -5.6 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf1N1B4_1535 -1.6 -3.2 hypothetical protein compare
Pf1N1B4_4833 -1.6 -3.8 DNA-binding response regulator, LuxR family compare
Pf1N1B4_2010 -1.6 -5.0 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf1N1B4_3697 -1.5 -6.8 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf1N1B4_1617 -1.5 -6.1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (EC 5.4.2.1) compare
Pf1N1B4_2009 -1.5 -4.6 LysR family transcriptional regulator PA5437 compare
Pf1N1B4_1317 -1.5 -2.7 Sensor histidine kinase/response regulator compare
Pf1N1B4_4065 -1.5 -6.0 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf1N1B4_1565 -1.4 -3.7 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf1N1B4_1519 -1.4 -3.4 3-oxoacyl-[ACP] reductase (EC 1.1.1.100) compare
Pf1N1B4_1625 -1.4 -4.2 FIG00956267: hypothetical protein compare
Pf1N1B4_3111 -1.3 -2.1 tRNA pseudouridine 13 synthase (EC 4.2.1.-) compare
Pf1N1B4_2674 -1.3 -1.9 hypothetical protein compare
Pf1N1B4_5699 -1.3 -2.2 ABC-type uncharacterized transport system, ATPase component compare
Pf1N1B4_2552 -1.3 -3.0 OsmC/Ohr family protein compare
Pf1N1B4_3325 -1.3 -1.4 Sigma factor RpoE negative regulatory protein RseB precursor compare
Pf1N1B4_348 -1.3 -3.6 Cyclohexadienyl dehydrogenase (EC 1.3.1.12)(EC 1.3.1.43) / 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19) compare
Pf1N1B4_4834 -1.3 -4.3 Sensor histidine kinase compare
Pf1N1B4_1906 -1.3 -3.0 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) compare
Pf1N1B4_5266 -1.3 -1.9 hypothetical protein compare
Pf1N1B4_2280 -1.3 -6.2 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf1N1B4_5407 -1.3 -2.0 hypothetical protein compare
Pf1N1B4_2283 -1.2 -2.0 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf1N1B4_4257 -1.2 -1.6 L-serine dehydratase, (PLP)-dependent (EC 4.3.1.17) @ Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf1N1B4_749 -1.2 -2.2 hypothetical protein compare
Pf1N1B4_2621 -1.2 -1.5 PspA/IM30 family protein compare
Pf1N1B4_2377 -1.2 -5.1 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf1N1B4_4030 -1.2 -2.8 NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3) compare
Pf1N1B4_69 -1.2 -2.2 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf1N1B4_2792 -1.2 -3.0 FIG00953454: hypothetical protein compare
Pf1N1B4_1695 -1.2 -1.5 Cystine ABC transporter, ATP-binding protein compare
Pf1N1B4_3672 -1.1 -3.7 small component of pyruvate transporter (yjcH-like) (from data) compare
Pf1N1B4_5834 -1.1 -2.4 Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B (EC 2.8.3.5) compare
Pf1N1B4_4029 -1.1 -2.5 NADH-ubiquinone oxidoreductase chain M (EC 1.6.5.3) compare
Pf1N1B4_4004 -1.1 -1.3 Peptidyl-prolyl cis-trans isomerase PpiB (EC 5.2.1.8) compare
Pf1N1B4_3726 -1.1 -3.8 Sensory box histidine kinase/response regulator compare
Pf1N1B4_5666 -1.1 -2.2 Oxidoreductase probably involved in sulfite reduction compare
Pf1N1B4_2493 -1.1 -2.3 Acyl-CoA dehydrogenase (EC 1.3.8.7) compare
Pf1N1B4_5433 -1.1 -2.1 hypothetical protein compare
Pf1N1B4_3098 -1.1 -2.3 Ribonuclease HII (EC 3.1.26.4) compare
Pf1N1B4_5311 -1.1 -1.3 hypothetical protein compare
Pf1N1B4_1370 -1.0 -1.5 Unsaturated fatty acid biosythesis repressor FabR, TetR family compare
Pf1N1B4_4103 -1.0 -1.9 Flagellar synthesis regulator FleN compare
Pf1N1B4_617 -1.0 -1.2 Carbamate kinase (EC 2.7.2.2) compare
Pf1N1B4_652 -1.0 -5.7 Sensory box histidine kinase compare
Pf1N1B4_5278 -1.0 -1.1 hypothetical protein compare
Pf1N1B4_2401 -1.0 -1.7 Lipoprotein, putative compare
Pf1N1B4_1590 -1.0 -3.7 Histidine utilization repressor compare
Pf1N1B4_3081 -1.0 -8.8 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
Pf1N1B4_3849 -1.0 -3.0 Transcriptional regulator, GntR family compare
Pf1N1B4_2684 -1.0 -1.5 Uncharacterized protein, similar to the N-terminal domain of Lon protease compare
Pf1N1B4_5074 -1.0 -1.9 Gluconate permease compare
Pf1N1B4_4028 -1.0 -2.4 NADH-ubiquinone oxidoreductase chain N (EC 1.6.5.3) compare
Pf1N1B4_5509 -1.0 -1.7 hypothetical protein compare
Pf1N1B4_1 -1.0 -1.6 Colicin V production protein compare
Pf1N1B4_1835 -1.0 -2.6 hypothetical protein compare
Pf1N1B4_4571 -1.0 -2.0 ADA regulatory protein / Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) compare
Pf1N1B4_1993 -1.0 -1.4 C4-type zinc finger protein, DksA/TraR family compare
Pf1N1B4_3149 -1.0 -1.8 hypothetical protein compare
Pf1N1B4_3506 -1.0 -4.2 Cysteine synthase B (EC 2.5.1.47) compare
Pf1N1B4_841 -1.0 -2.9 ABC-type sugar transport systems, ATPase components compare
Pf1N1B4_2856 -1.0 -2.7 Poly(A) polymerase (EC 2.7.7.19) compare
Pf1N1B4_5720 -1.0 -1.7 hypothetical protein compare
Pf1N1B4_4624 -1.0 -2.3 Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) compare
Pf1N1B4_5619 -1.0 -3.7 BarA-associated response regulator UvrY (= GacA = SirA) compare
Pf1N1B4_2734 -0.9 -1.5 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system compare
Pf1N1B4_2177 -0.9 -1.0 FIG00953342: hypothetical protein compare
Pf1N1B4_3153 -0.9 -1.6 hypothetical protein compare
Pf1N1B4_2874 -0.9 -1.5 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) compare
Pf1N1B4_3546 -0.9 -1.5 P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein compare
Pf1N1B4_2273 -0.9 -2.9 hypothetical protein compare
Pf1N1B4_669 -0.9 -2.4 INTEGRAL MEMBRANE PROTEIN (Rhomboid family) compare
Pf1N1B4_2682 -0.9 -1.6 Antiholin-like protein LrgA compare
Pf1N1B4_1610 -0.9 -2.3 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
Pf1N1B4_4039 -0.9 -3.8 NADH-ubiquinone oxidoreductase chain C (EC 1.6.5.3) / NADH-ubiquinone oxidoreductase chain D (EC 1.6.5.3) compare
Pf1N1B4_2695 -0.9 -1.7 Rare lipoprotein A precursor compare
Pf1N1B4_2339 -0.9 -1.4 COG1872 compare
Pf1N1B4_4043 -0.9 -1.7 Type II and III secretion system family protein compare
Pf1N1B4_257 -0.9 -3.6 sensor histidine kinase/response regulator compare
Pf1N1B4_3078 -0.9 -1.7 FIG138056: a glutathione-dependent thiol reductase compare
Pf1N1B4_883 -0.9 -1.3 Hypothetical nudix hydrolase YeaB compare
Pf1N1B4_3241 -0.9 -1.6 hypothetical protein compare
Pf1N1B4_2048 -0.9 -1.2 hypothetical protein compare
Pf1N1B4_5059 -0.9 -1.7 Transcriptional regulator, LysR family compare
Pf1N1B4_2860 -0.9 -3.4 FIG00954153: hypothetical protein compare
Pf1N1B4_222 -0.9 -2.3 Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4) compare
Pf1N1B4_5453 -0.9 -1.9 hypothetical protein compare
Pf1N1B4_4295 -0.8 -2.1 FIG00954434: hypothetical protein compare
Pf1N1B4_765 -0.8 -1.9 Cys-tRNA(Pro) deacylase YbaK compare
Pf1N1B4_4253 -0.8 -1.6 RNA polymerase sigma-70 factor, ECF subfamily compare
Pf1N1B4_1403 -0.8 -4.1 3'-to-5' exoribonuclease RNase R compare
Pf1N1B4_2706 -0.8 -1.8 FIG00954871: hypothetical protein compare
Pf1N1B4_3445 -0.8 -1.6 Succinylarginine dihydrolase (EC 3.5.3.23) compare
Pf1N1B4_157 -0.8 -2.0 ThiJ/PfpI family protein compare
Pf1N1B4_2869 -0.8 -3.0 lipoprotein, putative compare
Pf1N1B4_2112 -0.8 -6.0 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
Pf1N1B4_3685 -0.8 -2.4 Succinyl-CoA ligase [ADP-forming] alpha chain (EC 6.2.1.5) compare
Pf1N1B4_5018 -0.8 -1.9 FIG00962345: hypothetical protein compare
Pf1N1B4_4494 -0.8 -1.7 hypothetical protein compare
Pf1N1B4_3779 -0.8 -1.6 Hydrolase, alpha/beta fold family functionally coupled to Phosphoribulokinase compare
Pf1N1B4_4419 -0.8 -1.6 Organosulfonate utilization protein SsuF compare
Pf1N1B4_5519 -0.8 -1.6 hypothetical protein compare
Pf1N1B4_3599 -0.8 -3.1 Flagellar regulatory protein FleQ compare
Pf1N1B4_5254 -0.8 -2.1 hypothetical protein compare
Pf1N1B4_1583 -0.8 -2.0 Histidine ABC transporter, ATP-binding protein (TC 3.A.1) compare
Pf1N1B4_2005 -0.8 -1.0 ATP-dependent DNA helicase UvrD/PcrA compare
Pf1N1B4_381 -0.8 -1.5 hypothetical protein compare
Pf1N1B4_1266 -0.8 -1.5 hypothetical protein compare
Pf1N1B4_1113 -0.8 -3.3 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf1N1B4_3990 -0.8 -2.6 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
Pf1N1B4_106 -0.8 -2.3 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf1N1B4_1340 -0.8 -1.5 ABC transporter (iron.B12.siderophore.hemin) , periplasmic substrate-binding component compare
Pf1N1B4_5753 -0.8 -0.7 putative membrane protein compare
Pf1N1B4_1660 -0.8 -2.0 FIG00953324: hypothetical protein compare
Pf1N1B4_2857 -0.8 -2.0 Poly(A) polymerase (EC 2.7.7.19) compare
Pf1N1B4_4939 -0.8 -2.3 sodium/hydrogen exchanger family protein compare
Pf1N1B4_1003 -0.8 -1.6 Tryptophan synthase beta chain like (EC 4.2.1.20) compare
Pf1N1B4_2987 -0.8 -2.2 NAD-dependent formate dehydrogenase delta subunit compare
Pf1N1B4_3918 -0.8 -1.6 Thiamin biosynthesis lipoprotein ApbE compare
Pf1N1B4_3665 -0.8 -1.9 Transcriptional regulator, TetR family compare
Pf1N1B4_4393 -0.8 -1.0 Ferredoxin reductase compare
Pf1N1B4_4140 -0.8 -1.2 hypothetical protein compare
Pf1N1B4_4980 -0.8 -1.3 putative lipoprotein compare
Pf1N1B4_544 -0.8 -1.6 Small-conductance mechanosensitive channel compare
Pf1N1B4_623 -0.8 -1.3 Aminomethyltransferase (glycine cleavage system T protein) (EC 2.1.2.10) compare
Pf1N1B4_1566 -0.8 -3.1 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf1N1B4_4553 -0.8 -2.0 FIG00959354: hypothetical protein compare
Pf1N1B4_1107 -0.8 -2.4 D-galactarate dehydratase (EC 4.2.1.42) compare
Pf1N1B4_1118 -0.8 -1.6 Tryptophan synthase beta chain like (EC 4.2.1.20) compare
Pf1N1B4_2612 -0.8 -2.2 Putative transport protein compare
Pf1N1B4_1967 -0.7 -1.6 hypothetical protein compare
Pf1N1B4_1256 -0.7 -2.0 Transcriptional regulator, LysR family compare
Pf1N1B4_715 -0.7 -2.9 Iron-regulated protein A precursor compare
Pf1N1B4_4671 -0.7 -1.5 Short-chain dehydrogenase/reductase SDR compare
Pf1N1B4_2252 -0.7 -2.0 Organosulfonate utilization protein SsuF compare
Pf1N1B4_1299 -0.7 -3.0 FIG014328: hypothetical protein compare
Pf1N1B4_379 -0.7 -2.4 Protein of unknown function UPF0060 compare
Pf1N1B4_3836 -0.7 -0.9 Nitrite reductase [NAD(P)H] small subunit (EC 1.7.1.4) compare
Pf1N1B4_5005 -0.7 -2.0 LysR family transcriptional regulator STM2281 compare
Pf1N1B4_2489 -0.7 -1.8 Biotin synthesis protein BioH compare
Pf1N1B4_4259 -0.7 -1.2 hypothetical protein compare
Pf1N1B4_4857 -0.7 -3.0 Chemotaxis protein methyltransferase CheR (EC 2.1.1.80) compare
Pf1N1B4_4723 -0.7 -1.9 UPF0141 membrane protein YijP possibly required for phosphoethanolamine modification of lipopolysaccharide compare
Pf1N1B4_4824 -0.7 -1.5 Gamma-glutamyl-putrescine oxidase (EC1.4.3.-) compare
Pf1N1B4_1180 -0.7 -0.8 Outer membrane lipoprotein SmpA, a component of the essential YaeT outer-membrane protein assembly complex compare
Pf1N1B4_3350 -0.7 -1.4 FIG00954807: hypothetical protein compare
Pf1N1B4_4110 -0.7 -2.0 hypothetical protein compare
Pf1N1B4_4041 -0.7 -1.9 NADH ubiquinone oxidoreductase chain A (EC 1.6.5.3) compare
Pf1N1B4_3017 -0.7 -2.4 NAD(FAD)-utilizing enzyme possibly involved in translation compare
Pf1N1B4_5294 -0.7 -0.9 hypothetical protein compare
Pf1N1B4_5317 -0.7 -2.0 hypothetical protein compare
Pf1N1B4_131 -0.7 -1.5 hypothetical protein compare
Pf1N1B4_2209 -0.7 -3.4 Exopolyphosphatase (EC 3.6.1.11) compare


Specific Phenotypes

For 1 genes in this experiment

For carbon source Sodium pyruvate in Pseudomonas fluorescens FW300-N1B4

For carbon source Sodium pyruvate across organisms