Experiment set1IT019 for Sinorhizobium meliloti 1021

Compare to:

m-Inositol carbon source

200 most important genes:

  gene name fitness t score description  
SMc02899 -8.5 -10.2 prephenate dehydratase compare
SMc01843 -7.8 -11.9 5,10-methylenetetrahydrofolate reductase compare
SMc04405 -7.5 -11.5 3-isopropylmalate dehydrogenase compare
SMc02137 -7.4 -5.1 ornithine carbamoyltransferase compare
SMc02767 -7.4 -9.5 N-(5'-phosphoribosyl)anthranilate isomerase compare
SMc02766 -7.3 -18.4 tryptophan synthase subunit beta compare
SMc00235 -7.3 -8.7 anthranilate phosphoribosyltransferase compare
SMc03797 -7.1 -11.8 homoserine O-succinyltransferase compare
SMc04045 -7.1 -8.4 dihydroxy-acid dehydratase compare
SMc00917 -7.0 -6.8 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
SMc03777 -6.9 -8.2 gamma-glutamyl phosphate reductase compare
SMc02569 -6.8 -5.4 imidazole glycerol phosphate synthase subunit HisF compare
SMc02725 -6.8 -14.3 anthranilate synthase compare
SMc03776 -6.7 -4.6 gamma-glutamyl kinase compare
SMc02765 -6.7 -12.6 tryptophan synthase subunit alpha compare
SMa1635 -6.6 -2.5 hypothetical protein compare
SMc02717 -6.6 -16.6 2-isopropylmalate synthase compare
SMc03823 -6.5 -12.4 isopropylmalate isomerase large subunit compare
SMc00614 -6.4 -8.8 phosphoribosylglycinamide formyltransferase compare
SMc01726 -6.4 -5.6 acetylglutamate kinase compare
SMc00640 -6.3 -12.2 phosphoserine aminotransferase compare
SMc01801 -6.2 -4.0 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) compare
SMc00918 -6.1 -13.1 ATP phosphoribosyltransferase regulatory subunit compare
SMc03112 -5.9 -17.6 B12-dependent methionine synthase compare
SMc01431 -5.9 -19.4 acetolactate synthase 3 catalytic subunit compare
SMc00236 -5.9 -6.6 Indole-3-glycerol phosphate synthase compare
SMc04028 -5.7 -25.0 glutamate synthase compare
SMc01494 -5.6 -6.9 phosphoserine phosphatase compare
SMc01361 -5.6 -9.3 dihydroorotase compare
SMc00495 -5.5 -7.6 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
SMc04026 -5.5 -7.7 glutamate synthase compare
SMc00493 -5.5 -8.5 phosphoribosylformylglycinamidine synthase I compare
SMc01360 -5.4 -5.1 aspartate carbamoyltransferase catalytic subunit compare
SMc00494 -5.4 -2.8 phosphoribosylformylglycinamidine synthase subunit PurS compare
SMc00554 -5.3 -13.4 amidophosphoribosyltransferase compare
SMc02245 -5.3 -7.2 dihydroorotate dehydrogenase 2 compare
SMc01004 -5.3 -10.6 phosphoribosyl-AMP cyclohydrolase compare
SMc02755 -5.2 -7.2 S-adenosyl-L-homocysteine hydrolase compare
SMc00293 -5.1 -14.4 homoserine dehydrogenase compare
SMc02123 -5.1 -5.4 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
SMc01215 -5.1 -3.5 carbamoyl phosphate synthase large subunit compare
SMc02165 -5.0 -13.4 orotate phosphoribosyltransferase compare
SMc00993 -5.0 -12.3 phosphoribosylamine--glycine ligase compare
SMc01881 -5.0 -5.1 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
SMc03826 -5.0 -5.3 argininosuccinate synthase compare
SMc01569 -4.9 -2.5 carbamoyl phosphate synthase small subunit compare
SMc02707 -4.9 -6.2 hypothetical protein compare
SMc00488 -4.9 -15.4 phosphoribosylformylglycinamidine synthase II compare
SMc00711 -4.9 -4.2 cyclohexadienyl dehydrogenase compare
SMc02572 -4.9 -5.5 imidazole glycerol phosphate synthase subunit HisH compare
SMc04088 -4.8 -10.5 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase compare
SMc02124 -4.8 -16.3 nitrite reductase compare
SMc04002 -4.7 -5.9 phosphoribosylaminoimidazole carboxylase ATPase subunit compare
SMc00092 -4.7 -16.6 phosphoadenosine phosphosulfate reductase compare
SMc04001 -4.7 -1.8 phosphoribosylaminoimidazole carboxylase catalytic subunit protein compare
SMc00412 -4.7 -7.8 orotidine 5'-phosphate decarboxylase compare
SMc03763 -4.7 -4.6 cytosine-specific methyltransferase compare
SMc02217 -4.7 -7.3 O-succinylhomoserine sulfhydrylase compare
SMc01770 -4.6 -2.1 serine hydroxymethyltransferase compare
SMc03895 -4.6 -22.3 pyruvate carboxylase compare
SMc00131 -4.6 -15.4 transcriptional regulator compare
SMc00781 -4.6 -6.9 malonate-semialdehyde dehydrogenase (acetylating) (EC 1.2.1.18) (from data) conserved
SMc00017 -4.6 -2.4 homoserine kinase compare
SMc03978 -4.5 -4.4 transketolase compare
SMc02246 -4.5 -1.7 hypothetical protein compare
SMc03795 -4.4 -2.3 isopropylmalate isomerase small subunit compare
SMc00615 -4.4 -10.1 phosphoribosylaminoimidazole synthetase compare
SMc02138 -4.3 -7.7 acetylornithine transaminase compare
SMc00090 -4.3 -12.5 sulfate adenylyltransferase compare
SMc00432 -4.3 -12.7 5-deoxy-D-glucuronate isomerase (EC 5.3.1.30) (from data) conserved
SMc00876 -4.2 -8.6 ATP-binding MRP protein compare
SMc02574 -4.2 -7.4 imidazoleglycerol-phosphate dehydratase compare
SMc02570 -4.2 -5.5 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
SMc02307 -4.1 -8.8 histidinol dehydrogenase compare
SMc00294 -4.0 -14.4 aminotransferase compare
SMc00091 -4.0 -13.9 sulfate adenylyltransferase compare
SM_b20899 -4.0 -11.7 Inositol 2-dehydrogenase (EC 1.1.1.18) (from data) conserved
SMc02166 -3.9 -12.3 dihydroorotase compare
SMc00433 -3.7 -13.8 Myo-inosose-2 dehydratase (EC 4.2.1.44) (from data) conserved
SMc01880 -3.7 -5.5 pantoate--beta-alanine ligase compare
SM_b21174 -3.7 -6.5 phosphate uptake ABC transporter permease compare
SMc01165 -3.6 -20.5 5-dehydro-2-deoxygluconokinase (EC 2.7.1.92); possible 5-dehydro-2-deoxyphosphogluconate aldolase DUF2090 (EC 4.1.2.29) (from data) conserved
SMc00780 -3.5 -12.2 transcriptional regulator conserved
SMc00815 -3.5 -3.3 inosine 5'-monophosphate dehydrogenase compare
SMc03070 -3.5 -10.3 glucose-6-phosphate 1-dehydrogenase compare
SM_b21175 -3.5 -7.1 phosphate uptake ABC transporter permease compare
SMc01054 -3.4 -3.6 required for sulfate utilization, putative electron source for sulfite reductase CysI (from data) compare
SMc01053 -3.4 -5.3 siroheme synthase compare
SM_b21176 -3.4 -4.8 phosphate uptake ABC transporter substrate-binding protein precursor compare
SM_b21177 -3.4 -10.7 phosphate uptake ABC transporter ATP-binding protein compare
SM_b20713 -3.3 -10.6 sugar uptake ABC transporter ATP-binding protein conserved
SMc01166 -3.3 -8.3 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase IolD (EC 3.7.1.22) (from data) conserved
SMc00641 -3.2 -5.1 D-3-phosphoglycerate dehydrogenase compare
SMc04346 -3.2 -4.5 ketol-acid reductoisomerase compare
SMc01852 -2.9 -11.3 pyrophosphate--fructose-6-phosphate 1-phosphotransferase compare
SMc03981 -2.8 -4.7 phosphoglycerate kinase compare
SMc03100 -2.8 -2.3 hypothetical protein compare
SM_b20712 -2.8 -9.0 rhizopine uptake ABC transporter substrate-binding protein precursor conserved
SM_b20714 -2.7 -9.9 sugar uptake ABC transporter permease conserved
SMc02425 -2.7 -4.5 transcriptional regulator compare
SMc03974 -2.6 -5.4 hypothetical protein compare
SMc00296 -2.6 -11.1 POLY3-hydroxybutyrate polymerase compare
SMc01578 -2.3 -11.0 aspartate aminotransferase compare
SMc02983 -2.3 -6.4 ornithine, DAP, or arginine decarboxylase compare
SMc03153 -2.2 -4.1 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase compare
SMc00963 -2.2 -4.6 hypothetical protein compare
SMc03229 -2.1 -2.4 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase compare
SMc00619 -2.1 -1.5 hypothetical protein compare
SMc01441 -2.1 -8.2 membrane bound protease compare
SMc01430 -2.1 -5.0 acetolactate synthase 3 regulatory subunit compare
SMc01206 -2.0 -2.9 queuine tRNA-ribosyltransferase compare
SMc03979 -1.9 -2.3 glyceraldehyde-3-phosphate dehydrogenase compare
SMc01440 -1.9 -5.3 hydrolase serine protease transmembrane protein compare
SM_b20701 -1.8 -1.4 hypothetical protein compare
SMc01124 -1.7 -8.8 PII uridylyl-transferase compare
SMc02058 -1.7 -4.5 YAJC protein compare
SMc00987 -1.6 -3.6 hypothetical protein compare
SMc00982 -1.6 -7.7 dioxygenase compare
SMc02833 -1.6 -2.6 penicillin-insensitive murein endopeptidase compare
SMa1056 -1.6 -1.9 transcriptional regulator compare
SMc03069 -1.5 -3.8 6-phosphogluconolactonase compare
SMc00414 -1.5 -8.9 hypothetical protein compare
SMc00451 -1.3 -7.1 processing protease compare
SMc00334 -1.3 -2.6 cytidylate kinase compare
SMa0144 -1.3 -1.2 hypothetical protein compare
SM_b20021 -1.2 -1.2 transcriptional regulator compare
SMc02640 -1.2 -3.2 UDP-glucuronic acid epimerase compare
SMc01023 -1.2 -3.5 triosephosphate isomerase compare
SMc02385 -1.1 -2.9 hypothetical protein compare
SM_b21192 -1.1 -7.1 fructose-1,6-bisphosphate aldolase compare
SMc01842 -1.1 -1.1 methyltransferase transcription regulator protein compare
SMc00726 -1.1 -0.9 thiol:disulfide interchange redox-active center transmembrane protein compare
SMc03993 -1.1 -3.7 hypothetical protein compare
SMc04330 -1.1 -2.6 trimethylamine methyltransferase compare
SMc04174 -1.1 -1.4 signal peptide protein compare
SMc02659 -1.0 -4.9 GTP pyrophosphokinase (ATP:GTP 3'-pyrophosphotransferase) protein compare
SMc00709 -1.0 -4.3 hypothetical protein compare
SMc01850 -1.0 -3.5 hypothetical protein compare
SMc00981 -1.0 -5.2 ferredoxin protein compare
SM_b22001 -1.0 -1.4 hypothetical protein compare
SMc00405 -1.0 -4.0 hypothetical protein compare
SM_b21480 -1.0 -1.3 hypothetical protein compare
SMc02581 -1.0 -7.1 malate synthase G compare
SMc04000 -0.9 -0.6 hypothetical protein compare
SMc01147 -0.9 -2.0 coproporphyrinogen III oxidase compare
SMc02753 -0.9 -1.5 PTS system transporter subunit IIA compare
SMc01364 -0.9 -1.0 DNA topoisomerase I compare
SMc01845 -0.9 -2.1 transglycosylase transmembrane protein compare
SM_b20251 -0.9 -4.0 hypothetical protein compare
SMc00295 -0.9 -1.3 hypothetical protein compare
SMa1658 -0.9 -1.3 hypothetical protein compare
SMc02812 -0.9 -2.1 hypothetical protein compare
SMc01368 -0.9 -3.0 transport transmembrane protein compare
SM_b20293 -0.9 -1.2 hypothetical protein compare
SMc02149 -0.9 -1.8 hypothetical protein compare
SMc00838 -0.9 -4.0 hypothetical protein compare
SM_b20114 -0.9 -2.3 hypothetical protein compare
SMc03924 -0.9 -4.9 glycogen synthase compare
SMc02495 -0.9 -1.0 translaldolase compare
SM_b20249 -0.8 -2.8 myo-inositol-1-phosphate synthase compare
SMc02407 -0.8 -3.8 hypothetical protein compare
SMc01097 -0.8 -3.9 hypothetical protein compare
SM_b21400 -0.8 -2.1 hypothetical protein compare
SMc00286 -0.8 -0.8 hemolysin-type calcium-binding protein compare
SMc02521 -0.8 -1.9 glycerol-3-phosphate regulon repressor transcription regulator protein compare
SMc00579 -0.8 -2.4 dimethyladenosine transferase compare
SMc02641 -0.8 -2.9 UDP-glucose 6-dehydrogenase compare
SMc01183 -0.8 -1.0 LexA repressor compare
SMc00821 -0.8 -1.1 hypothetical protein compare
SMc02141 -0.8 -3.6 phosphate transporter PhoU compare
SMc03878 -0.8 -2.7 acetoacetyl-CoA reductase compare
SMc00710 -0.8 -3.6 histidinol-phosphate aminotransferase compare
SMc00928 -0.8 -0.9 signal peptide protein compare
SMc00288 -0.8 -4.7 signal peptide protein compare
SMc04296 -0.8 -1.1 cell division protein FtsZ compare
SMc03279 -0.8 -1.9 transposase number 2 for insertion sequence ISRM28 compare
SMc00191 -0.8 -1.7 hypothetical protein compare
SMa0050 -0.7 -1.2 hypothetical protein compare
SMc01723 -0.7 -0.9 hypothetical protein compare
SMc02861 -0.7 -1.6 phosphate transporter compare
SMc02373 -0.7 -1.1 hypothetical protein compare
SMc03242 -0.7 -1.9 GTP-binding protein compare
SMc02683 -0.7 -1.3 hypothetical protein compare
SMc02677 -0.7 -3.3 pyrroline-5-carboxylate reductase compare
SMc00053 -0.7 -0.7 monovalent cation/H+ antiporter subunit C compare
SMc04024 -0.7 -3.4 membrane-bound lytic murein transglycosylase compare
SM_b20897 -0.7 -1.1 hypothetical protein compare
SM_b21130 -0.7 -2.9 sulfate ABC transporter ATP-binding protein compare
SMc00080 -0.7 -1.2 hypothetical protein compare
SMa0905 -0.7 -1.1 hypothetical protein compare
SMc02451 -0.7 -1.0 hypothetical protein compare
SMc02227 -0.7 -3.2 fatty oxidation complex enoyl-COA hydratase/3-hydroxyacyl-COA dehydrogenase/3-hydroxybutyryl-COA epimerase compare
SMc00353 -0.7 -1.2 transmembrane protein compare
SMc03935 -0.7 -4.4 hypothetical protein compare
SMc01447 -0.7 -1.0 hypothetical protein compare
SM_b20898 -0.7 -3.2 hypothetical protein compare
SMc01260 -0.7 -2.5 transcriptional regulator compare
SMc02308 -0.7 -2.5 hypothetical protein compare
SM_b20823 -0.7 -4.0 cell surface saccharide synthesis protein compare
SM_b21470 -0.7 -3.0 hypothetical protein compare


Specific Phenotypes

For 10 genes in this experiment

For carbon source m-Inositol in Sinorhizobium meliloti 1021

For carbon source m-Inositol across organisms