Experiment set1IT018 for Pseudomonas fluorescens FW300-N1B4

Compare to:

Sodium D,L-Lactate carbon source

200 most important genes:

  gene name fitness t score description  
Pf1N1B4_5370 -3.7 -2.5 hypothetical protein compare
Pf1N1B4_1307 -3.7 -2.5 3-dehydroquinate dehydratase II (EC 4.2.1.10) compare
Pf1N1B4_3506 -3.5 -7.8 Cysteine synthase B (EC 2.5.1.47) compare
Pf1N1B4_1624 -3.5 -9.5 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf1N1B4_15 -3.4 -4.6 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf1N1B4_2549 -3.3 -9.8 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf1N1B4_1408 -3.3 -5.4 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf1N1B4_3518 -3.2 -4.6 Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) compare
Pf1N1B4_2880 -3.1 -12.3 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf1N1B4_1534 -3.1 -18.0 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf1N1B4_742 -3.1 -8.4 Argininosuccinate synthase (EC 6.3.4.5) compare
Pf1N1B4_5666 -3.1 -3.6 Oxidoreductase probably involved in sulfite reduction compare
Pf1N1B4_1831 -3.1 -11.6 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf1N1B4_1434 -3.0 -8.0 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf1N1B4_1188 -3.0 -11.0 Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF conserved
Pf1N1B4_1315 -3.0 -8.6 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) compare
Pf1N1B4_1533 -2.9 -8.8 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf1N1B4_6 -2.9 -5.8 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf1N1B4_2858 -2.9 -11.2 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf1N1B4_1830 -2.9 -9.0 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf1N1B4_2548 -2.9 -7.5 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf1N1B4_1189 -2.9 -5.7 Predicted L-lactate dehydrogenase, hypothetical protein subunit YkgG compare
Pf1N1B4_2010 -2.8 -6.3 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf1N1B4_2303 -2.8 -14.1 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf1N1B4_2545 -2.8 -13.9 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
Pf1N1B4_2009 -2.8 -6.1 LysR family transcriptional regulator PA5437 compare
Pf1N1B4_12 -2.8 -7.6 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf1N1B4_1565 -2.8 -4.9 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf1N1B4_2879 -2.7 -7.3 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf1N1B4_2282 -2.7 -9.5 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf1N1B4_2547 -2.7 -3.6 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
Pf1N1B4_5665 -2.7 -6.2 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf1N1B4_1626 -2.7 -7.4 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf1N1B4_2878 -2.6 -8.6 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf1N1B4_2338 -2.6 -8.5 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf1N1B4_3697 -2.6 -8.9 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf1N1B4_847 -2.6 -9.4 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf1N1B4_762 -2.6 -6.7 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf1N1B4_2272 -2.6 -4.8 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf1N1B4_1186 -2.5 -9.8 L-lactate permease conserved
Pf1N1B4_1617 -2.5 -7.8 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (EC 5.4.2.1) compare
Pf1N1B4_1067 -2.5 -6.4 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf1N1B4_1627 -2.5 -5.2 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf1N1B4_2384 -2.5 -10.1 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf1N1B4_3812 -2.4 -8.5 Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) compare
Pf1N1B4_4065 -2.4 -8.4 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf1N1B4_2011 -2.3 -9.0 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf1N1B4_1187 -2.3 -7.0 Predicted L-lactate dehydrogenase, Fe-S oxidoreductase subunit YkgE conserved
Pf1N1B4_350 -2.2 -6.8 Chorismate mutase I (EC 5.4.99.5) / Prephenate dehydratase (EC 4.2.1.51) compare
Pf1N1B4_2486 -2.0 -2.9 hypothetical protein compare
Pf1N1B4_2337 -2.0 -5.5 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf1N1B4_2112 -1.9 -12.1 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
Pf1N1B4_1906 -1.9 -3.8 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) compare
Pf1N1B4_644 -1.9 -2.2 Cold shock protein CspC compare
Pf1N1B4_2859 -1.9 -12.6 Two-component sensor CbrA: intrcellular carbon:nitrogen balance compare
Pf1N1B4_5371 -1.9 -1.9 hypothetical protein compare
Pf1N1B4_2280 -1.9 -8.1 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf1N1B4_1 -1.7 -2.7 Colicin V production protein compare
Pf1N1B4_3549 -1.7 -2.8 YciL protein compare
Pf1N1B4_5476 -1.7 -1.7 hypothetical protein compare
Pf1N1B4_3081 -1.7 -13.7 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
Pf1N1B4_652 -1.6 -8.1 Sensory box histidine kinase compare
Pf1N1B4_3935 -1.5 -3.3 Major facilitator family transporter compare
Pf1N1B4_2377 -1.5 -6.0 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf1N1B4_716 -1.5 -3.3 Probable thiol oxidoreductase with 2 cytochrome c heme-binding sites compare
Pf1N1B4_751 -1.5 -1.7 hypothetical protein compare
Pf1N1B4_365 -1.5 -4.9 Cell division protein BolA compare
Pf1N1B4_578 -1.5 -2.4 enoyl-CoA hydratase, R-specific compare
Pf1N1B4_2807 -1.5 -2.6 FKBP-type peptidyl-prolyl cis-trans isomerase SlpA (EC 5.2.1.8) compare
Pf1N1B4_4336 -1.5 -2.4 FMN-dependent NADH-azoreductase compare
Pf1N1B4_2487 -1.4 -7.1 Biotin synthase (EC 2.8.1.6) compare
Pf1N1B4_1566 -1.4 -5.5 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf1N1B4_2949 -1.4 -2.1 FIG00956396: hypothetical protein compare
Pf1N1B4_3917 -1.4 -3.7 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf1N1B4_1653 -1.3 -5.6 Branched-chain amino acid transport protein AzlC compare
Pf1N1B4_1610 -1.3 -3.8 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
Pf1N1B4_1916 -1.3 -2.0 Chaperone protein YscY (Yop proteins translocation protein Y) compare
Pf1N1B4_769 -1.3 -5.1 Aerobic glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) compare
Pf1N1B4_2791 -1.3 -2.4 Putative inner membrane protein (Fragment) compare
Pf1N1B4_3222 -1.3 -2.0 Ferredoxin compare
Pf1N1B4_1819 -1.3 -3.3 NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2) compare
Pf1N1B4_1317 -1.3 -2.6 Sensor histidine kinase/response regulator compare
Pf1N1B4_1190 -1.3 -6.8 Predicted D-lactate dehydrogenase, Fe-S protein, FAD/FMN-containing conserved
Pf1N1B4_35 -1.2 -2.9 hypothetical protein compare
Pf1N1B4_372 -1.2 -2.7 UDP-galactose-lipid carrier transferase (EC 2.-.-.-) compare
Pf1N1B4_27 -1.2 -3.5 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf1N1B4_412 -1.2 -2.5 L-arabinose 1-dehydrogenase / D-galactose 1-dehydrogenase (EC 1.1.1.46; EC 1.1.1.48) (from data) compare
Pf1N1B4_3685 -1.2 -3.6 Succinyl-CoA ligase [ADP-forming] alpha chain (EC 6.2.1.5) compare
Pf1N1B4_3795 -1.2 -2.2 3-ketoacyl-CoA thiolase (EC 2.3.1.16) @ Acetyl-CoA acetyltransferase (EC 2.3.1.9) compare
Pf1N1B4_3241 -1.2 -2.1 hypothetical protein compare
Pf1N1B4_1057 -1.2 -2.2 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf1N1B4_3751 -1.2 -1.9 FIG00953060: hypothetical protein compare
Pf1N1B4_5302 -1.2 -2.4 hypothetical protein compare
Pf1N1B4_5447 -1.1 -1.8 hypothetical protein compare
Pf1N1B4_2706 -1.1 -2.5 FIG00954871: hypothetical protein compare
Pf1N1B4_717 -1.1 -4.4 Iron-regulated protein A precursor compare
Pf1N1B4_230 -1.1 -1.8 FIG00953472: hypothetical protein compare
Pf1N1B4_5330 -1.1 -1.6 hypothetical protein compare
Pf1N1B4_2488 -1.1 -4.9 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf1N1B4_275 -1.0 -1.7 Organic hydroperoxide resistance transcriptional regulator compare
Pf1N1B4_1870 -1.0 -2.2 Zinc ABC transporter, ATP-binding protein ZnuC compare
Pf1N1B4_3325 -1.0 -1.9 Sigma factor RpoE negative regulatory protein RseB precursor compare
Pf1N1B4_1568 -1.0 -2.4 Twin-arginine translocation protein TatB compare
Pf1N1B4_3985 -1.0 -1.2 Methylglutaconyl-CoA hydratase (EC 4.2.1.18) compare
Pf1N1B4_5804 -1.0 -2.1 Muconolactone isomerase (EC 5.3.3.4) compare
Pf1N1B4_718 -1.0 -4.4 outer membrane component of uptake system, probably for ferrous iron (from data) compare
Pf1N1B4_1636 -1.0 -1.4 FIG00954739: hypothetical protein compare
Pf1N1B4_348 -1.0 -2.8 Cyclohexadienyl dehydrogenase (EC 1.3.1.12)(EC 1.3.1.43) / 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19) compare
Pf1N1B4_364 -1.0 -3.0 Rhodanese domain protein UPF0176 compare
Pf1N1B4_4208 -1.0 -1.7 organophosphate pesticide hydrolase compare
Pf1N1B4_4887 -1.0 -2.2 Pirin compare
Pf1N1B4_2860 -1.0 -4.3 FIG00954153: hypothetical protein compare
Pf1N1B4_2005 -0.9 -1.2 ATP-dependent DNA helicase UvrD/PcrA compare
Pf1N1B4_5917 -0.9 -1.6 Multimeric flavodoxin WrbA compare
Pf1N1B4_5288 -0.9 -2.5 hypothetical protein compare
Pf1N1B4_1625 -0.9 -2.5 FIG00956267: hypothetical protein compare
Pf1N1B4_458 -0.9 -2.9 Similar to phosphoglycolate phosphatase, clustered with ribosomal large subunit pseudouridine synthase C compare
Pf1N1B4_4343 -0.9 -1.8 hypothetical protein compare
Pf1N1B4_3849 -0.9 -2.9 Transcriptional regulator, GntR family compare
Pf1N1B4_715 -0.9 -3.6 Iron-regulated protein A precursor compare
Pf1N1B4_5561 -0.9 -2.1 hypothetical protein compare
Pf1N1B4_2948 -0.9 -1.9 FIG00954698: hypothetical protein compare
Pf1N1B4_4494 -0.9 -2.5 hypothetical protein compare
Pf1N1B4_3305 -0.9 -2.2 Urea carboxylase-related ABC transporter, permease protein compare
Pf1N1B4_4824 -0.9 -1.9 Gamma-glutamyl-putrescine oxidase (EC1.4.3.-) compare
Pf1N1B4_257 -0.9 -3.7 sensor histidine kinase/response regulator compare
Pf1N1B4_5383 -0.9 -4.9 hypothetical protein compare
Pf1N1B4_3729 -0.9 -1.7 Quaternary ammonium compound-resistance protein SugE compare
Pf1N1B4_2490 -0.9 -3.7 Biotin synthesis protein BioC compare
Pf1N1B4_5386 -0.9 -1.6 hypothetical protein compare
Pf1N1B4_22 -0.8 -3.7 Transcriptional regulator, TetR family compare
Pf1N1B4_1584 -0.8 -1.2 Histidine ABC transporter, permease protein (TC 3.A.1) compare
Pf1N1B4_2674 -0.8 -1.4 hypothetical protein compare
Pf1N1B4_366 -0.8 -4.4 FIG00954136: hypothetical protein compare
Pf1N1B4_5490 -0.8 -2.5 hypothetical protein compare
Pf1N1B4_5659 -0.8 -5.4 NfuA Fe-S protein maturation compare
Pf1N1B4_4765 -0.8 -1.7 2-ketogluconate kinase (EC 2.7.1.13) compare
Pf1N1B4_2682 -0.8 -1.5 Antiholin-like protein LrgA compare
Pf1N1B4_5690 -0.8 -1.6 Putative TEGT family carrier/transport protein compare
Pf1N1B4_3445 -0.8 -2.2 Succinylarginine dihydrolase (EC 3.5.3.23) compare
Pf1N1B4_3581 -0.8 -2.4 UDP-glucose 4-epimerase (EC 5.1.3.2) compare
Pf1N1B4_2568 -0.8 -2.0 Translation elongation factor Tu compare
Pf1N1B4_2225 -0.8 -5.5 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) compare
Pf1N1B4_1535 -0.8 -2.0 hypothetical protein compare
Pf1N1B4_2912 -0.8 -1.3 GTP-binding and nucleic acid-binding protein YchF compare
Pf1N1B4_3443 -0.8 -1.8 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf1N1B4_4257 -0.8 -1.3 L-serine dehydratase, (PLP)-dependent (EC 4.3.1.17) @ Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf1N1B4_4568 -0.8 -1.2 FIG00793915: hypothetical protein compare
Pf1N1B4_6037 -0.8 -2.0 L-asparaginase (EC 3.5.1.1) compare
Pf1N1B4_1742 -0.8 -2.5 Biofilm PGA synthesis auxiliary protein PgaD compare
Pf1N1B4_2734 -0.8 -1.3 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system compare
Pf1N1B4_3742 -0.8 -1.2 Oxidoreductase, zinc-binding compare
Pf1N1B4_3330 -0.8 -3.0 Thiol peroxidase, Bcp-type (EC 1.11.1.15) compare
Pf1N1B4_866 -0.8 -1.3 Iron-sulfur cluster regulator IscR compare
Pf1N1B4_5219 -0.8 -1.9 tRNA-Gly-CCC compare
Pf1N1B4_1869 -0.8 -3.7 Zinc ABC transporter, inner membrane permease protein ZnuB compare
Pf1N1B4_1611 -0.8 -2.8 Nitrogen regulation protein NR(I) compare
Pf1N1B4_4566 -0.8 -2.2 Universal stress protein family 7 compare
Pf1N1B4_1579 -0.8 -2.2 Imidazolonepropionase (EC 3.5.2.7) (from data) compare
Pf1N1B4_2868 -0.8 -2.6 ABC-type hemin transport system, ATPase component compare
Pf1N1B4_2489 -0.8 -3.1 Biotin synthesis protein BioH compare
Pf1N1B4_1263 -0.8 -1.7 Cu(I)-responsive transcriptional regulator compare
Pf1N1B4_1749 -0.8 -1.1 Prevent host death protein, Phd antitoxin compare
Pf1N1B4_5487 -0.8 -1.8 hypothetical protein compare
Pf1N1B4_5472 -0.8 -2.3 hypothetical protein compare
Pf1N1B4_4857 -0.8 -3.4 Chemotaxis protein methyltransferase CheR (EC 2.1.1.80) compare
Pf1N1B4_5284 -0.7 -1.4 hypothetical protein compare
Pf1N1B4_1695 -0.7 -1.1 Cystine ABC transporter, ATP-binding protein compare
Pf1N1B4_2958 -0.7 -1.8 Medium-chain-fatty-acid--CoA ligase (EC 6.2.1.-) compare
Pf1N1B4_2418 -0.7 -2.9 HTH-type transcriptional regulator BetI compare
Pf1N1B4_1542 -0.7 -1.8 Type IV pilus biogenesis protein PilN compare
Pf1N1B4_1872 -0.7 -3.8 Zinc ABC transporter, periplasmic-binding protein ZnuA compare
Pf1N1B4_5402 -0.7 -1.3 hypothetical protein compare
Pf1N1B4_3709 -0.7 -2.2 Adenosylcobinamide-phosphate synthase (EC 6.3.1.10) compare
Pf1N1B4_5433 -0.7 -1.6 hypothetical protein compare
Pf1N1B4_2163 -0.7 -1.1 hypothetical protein compare
Pf1N1B4_1569 -0.7 -4.9 Twin-arginine translocation protein TatC compare
Pf1N1B4_1300 -0.7 -2.1 hypothetical protein compare
Pf1N1B4_3524 -0.7 -2.1 FIG00955363: hypothetical protein compare
Pf1N1B4_3152 -0.7 -2.6 LysR family transcriptional regulator PA3398 compare
Pf1N1B4_2290 -0.7 -2.0 Cd(II)/Pb(II)-responsive transcriptional regulator compare
Pf1N1B4_2144 -0.7 -3.8 D-amino acid dehydrogenase small subunit (EC 1.4.99.1) compare
Pf1N1B4_564 -0.7 -1.7 ABC-type phosphate/phosphonate transport system, periplasmic component compare
Pf1N1B4_1059 -0.7 -1.5 FIG137478: Hypothetical protein YbgI compare
Pf1N1B4_5552 -0.7 -1.3 hypothetical protein compare
Pf1N1B4_1936 -0.7 -2.8 Chromosome (plasmid) partitioning protein ParA compare
Pf1N1B4_5892 -0.7 -2.1 FIG00961753: hypothetical protein compare
Pf1N1B4_165 -0.7 -1.6 FIG00638667: hypothetical protein compare
Pf1N1B4_1399 -0.7 -2.0 FIG003573: hypothetical protein compare
Pf1N1B4_4352 -0.7 -1.6 Putrescine transport ATP-binding protein PotG (TC 3.A.1.11.2) compare
Pf1N1B4_3802 -0.7 -1.2 PlcB, ORFX, ORFP, ORFB, ORFA, ldh gene compare
Pf1N1B4_3350 -0.7 -1.6 FIG00954807: hypothetical protein compare
Pf1N1B4_197 -0.7 -1.5 FIG139991: Putative thiamine pyrophosphate-requiring enzyme compare
Pf1N1B4_770 -0.7 -1.3 hypothetical protein compare
Pf1N1B4_1251 -0.7 -2.1 2-Oxobutyrate oxidase, putative compare
Pf1N1B4_2209 -0.7 -4.0 Exopolyphosphatase (EC 3.6.1.11) compare
Pf1N1B4_3148 -0.7 -2.4 FIG074102: hypothetical protein compare
Pf1N1B4_1668 -0.7 -2.5 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
Pf1N1B4_4123 -0.7 -1.4 Isochorismate pyruvate-lyase (EC 4.-.-.-) compare
Pf1N1B4_76 -0.7 -1.6 ATP binding protein compare


Specific Phenotypes

For 4 genes in this experiment

For carbon source Sodium D,L-Lactate in Pseudomonas fluorescens FW300-N1B4

For carbon source Sodium D,L-Lactate across organisms