Experiment set1IT018 for Pseudomonas fluorescens FW300-N1B4

Compare to:

Sodium D,L-Lactate carbon source

200 most detrimental genes:

  gene name fitness t score description  
Pf1N1B4_3501 +1.5 9.4 BarA sensory histidine kinase (= VarS = GacS) compare
Pf1N1B4_2284 +1.5 7.1 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
Pf1N1B4_2060 +1.5 3.9 hypothetical protein compare
Pf1N1B4_3115 +1.4 10.0 RNA polymerase sigma factor RpoS compare
Pf1N1B4_5242 +1.2 2.0 hypothetical protein compare
Pf1N1B4_4855 +1.1 3.7 Response regulator compare
Pf1N1B4_1504 +1.1 2.7 Acyl carrier protein compare
Pf1N1B4_3582 +1.1 2.4 C-methyltransferase compare
Pf1N1B4_507 +1.0 1.9 FIG00956448: hypothetical protein compare
Pf1N1B4_1511 +1.0 2.2 FIG027190: Putative transmembrane protein compare
Pf1N1B4_4024 +0.9 2.6 Tryptophan synthase beta chain like (EC 4.2.1.20) compare
Pf1N1B4_2980 +0.9 3.3 Acetylornithine aminotransferase (EC 2.6.1.11) compare
Pf1N1B4_5574 +0.9 2.5 hypothetical protein compare
Pf1N1B4_188 +0.9 1.9 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf1N1B4_4422 +0.9 2.0 ABC transporter amino acid-binding protein compare
Pf1N1B4_5331 +0.9 2.2 hypothetical protein compare
Pf1N1B4_4256 +0.9 2.9 Probable transmembrane protein compare
Pf1N1B4_883 +0.8 1.4 Hypothetical nudix hydrolase YeaB compare
Pf1N1B4_904 +0.8 2.2 DNA-binding protein HU-beta compare
Pf1N1B4_124 +0.8 2.1 Mechanosensitive ion channel compare
Pf1N1B4_4509 +0.8 1.5 Aldose 1-epimerase compare
Pf1N1B4_218 +0.8 5.3 Periplasmic binding protein compare
Pf1N1B4_823 +0.8 2.1 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf1N1B4_3775 +0.8 2.1 FIG00956876: hypothetical protein compare
Pf1N1B4_387 +0.8 2.1 hypothetical protein compare
Pf1N1B4_5746 +0.8 2.3 FIG139552: Putative protease compare
Pf1N1B4_5601 +0.8 3.3 FIG00966546: hypothetical protein compare
Pf1N1B4_3291 +0.8 2.3 Putative subunit of Alternative cytochrome c oxidase compare
Pf1N1B4_5619 +0.8 3.2 BarA-associated response regulator UvrY (= GacA = SirA) compare
Pf1N1B4_5283 +0.8 2.0 hypothetical protein compare
Pf1N1B4_2713 +0.8 2.1 FIG00955339: hypothetical protein compare
Pf1N1B4_2178 +0.7 1.4 Regulator of nucleoside diphosphate kinase compare
Pf1N1B4_1105 +0.7 1.7 4-carboxymuconolactone decarboxylase (EC 4.1.1.44) compare
Pf1N1B4_483 +0.7 1.8 Metal-dependent hydrolase related to alanyl-tRNA synthetase compare
Pf1N1B4_3408 +0.7 1.6 Transcriptional regulator, AraC family compare
Pf1N1B4_1888 +0.7 3.1 Glutamate-aspartate carrier protein compare
Pf1N1B4_338 +0.7 2.0 Alpha-L-Rha alpha-1,3-L-rhamnosyltransferase (EC 2.4.1.-) compare
Pf1N1B4_1561 +0.7 2.1 FIG00954300: hypothetical protein compare
Pf1N1B4_740 +0.7 1.8 Leucyl-tRNA synthetase compare
Pf1N1B4_1679 +0.7 1.6 Membrane-fusion protein compare
Pf1N1B4_3911 +0.7 2.9 Predicted transcriptional regulator for fatty acid degradation FadQ, TetR family compare
Pf1N1B4_1460 +0.7 5.6 Lipid A core - O-antigen ligase and related enzymes compare
Pf1N1B4_606 +0.7 1.7 Iron siderophore sensor protein compare
Pf1N1B4_825 +0.7 1.7 tRNA (uridine-5-oxyacetic acid methyl ester) 34 synthase compare
Pf1N1B4_5483 +0.7 1.3 hypothetical protein compare
Pf1N1B4_2047 +0.7 2.6 Chorismate--pyruvate lyase (EC 4.1.3.40) compare
Pf1N1B4_4669 +0.7 1.1 Heavy metal RND efflux outer membrane protein, CzcC family compare
Pf1N1B4_4937 +0.7 2.8 Two-component hybrid sensor and regulator compare
Pf1N1B4_1463 +0.7 4.9 hypothetical protein compare
Pf1N1B4_1461 +0.7 2.8 Protein fixF compare
Pf1N1B4_1052 +0.7 1.5 FKBP-type peptidyl-prolyl cis-trans isomerase SlyD (EC 5.2.1.8) compare
Pf1N1B4_313 +0.6 1.5 Potassium-transporting ATPase C chain (EC 3.6.3.12) (TC 3.A.3.7.1) compare
Pf1N1B4_5715 +0.6 3.4 RND efflux membrane fusion protein compare
Pf1N1B4_4038 +0.6 1.7 NADH-ubiquinone oxidoreductase chain E (EC 1.6.5.3) compare
Pf1N1B4_2232 +0.6 2.7 Ferric iron ABC transporter, iron-binding protein compare
Pf1N1B4_2083 +0.6 2.5 Uncharacterized protein ImpB compare
Pf1N1B4_3588 +0.6 1.6 N-Acetylneuraminate cytidylyltransferase (EC 2.7.7.43) compare
Pf1N1B4_4799 +0.6 1.5 Multidrug resistance protein B compare
Pf1N1B4_906 +0.6 2.3 Glutaredoxin NrdH compare
Pf1N1B4_2464 +0.6 2.0 Ribosomal protein S6 glutaminyl transferase compare
Pf1N1B4_5820 +0.6 2.3 Transcriptional regulator, Cro/CI family compare
Pf1N1B4_5604 +0.6 2.1 Permeases of the major facilitator superfamily compare
Pf1N1B4_4860 +0.6 1.6 Sensory box sensor histidine kinase/response regulator (EC 2.7.3.-) compare
Pf1N1B4_4429 +0.6 1.6 No significant database matches compare
Pf1N1B4_4455 +0.6 1.6 FIG00953528: hypothetical protein compare
Pf1N1B4_3889 +0.6 1.7 hypothetical protein compare
Pf1N1B4_4822 +0.6 1.8 Paraquat-inducible protein A compare
Pf1N1B4_1482 +0.6 2.0 hypothetical protein compare
Pf1N1B4_4134 +0.6 1.5 Na+ driven multidrug efflux pump compare
Pf1N1B4_1127 +0.6 3.7 Dipeptide transport ATP-binding protein DppF (TC 3.A.1.5.2) compare
Pf1N1B4_2476 +0.6 3.9 Predicted signal-transduction protein containing cAMP-binding and CBS domains compare
Pf1N1B4_2750 +0.6 1.2 3-dehydroquinate dehydratase II (EC 4.2.1.10) compare
Pf1N1B4_3613 +0.6 1.5 hypothetical protein compare
Pf1N1B4_5306 +0.6 1.3 hypothetical protein compare
Pf1N1B4_741 +0.6 2.3 DNA-binding response regulator, LuxR family compare
Pf1N1B4_879 +0.6 2.6 Phosphoribosylglycinamide formyltransferase 2 (EC 2.1.2.-) compare
Pf1N1B4_4358 +0.6 1.3 Acetyltransferase, GNAT family compare
Pf1N1B4_5620 +0.6 1.3 Protein export cytoplasm protein SecA ATPase RNA helicase (TC 3.A.5.1.1) compare
Pf1N1B4_4776 +0.6 2.2 Nicotinamidase (EC 3.5.1.19) compare
Pf1N1B4_5365 +0.6 1.4 hypothetical protein compare
Pf1N1B4_1806 +0.6 2.1 FIG00953743: hypothetical protein compare
Pf1N1B4_5886 +0.6 2.3 Undecaprenyl-phosphate galactosephosphotransferase (EC 2.7.8.6) compare
Pf1N1B4_201 +0.6 1.4 ABC transporter in pyoverdin gene cluster, ATP-binding component compare
Pf1N1B4_5055 +0.6 2.2 (R)-3-hydroxydecanoyl-ACP:CoA transacylase PhaG (3-hydroxyacyl-CoA-acyl carrier protein transferase) (EC 2.4.1.-) compare
Pf1N1B4_3794 +0.6 1.8 hypothetical protein compare
Pf1N1B4_5355 +0.6 2.6 hypothetical protein compare
Pf1N1B4_5697 +0.6 2.4 putative exported protein compare
Pf1N1B4_2939 +0.6 2.9 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf1N1B4_5580 +0.6 2.8 Probable poly(beta-D-mannuronate) O-acetylase (EC 2.3.1.-) compare
Pf1N1B4_1671 +0.6 1.8 FIG00954962: hypothetical protein compare
Pf1N1B4_290 +0.6 5.3 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf1N1B4_4481 +0.6 1.4 Transcriptional regulator BkdR of isoleucine and valine catabolism operon compare
Pf1N1B4_5777 +0.6 1.6 Nitrous oxide reductase maturation protein, outer-membrane lipoprotein NosL compare
Pf1N1B4_2643 +0.6 1.4 Predicted zinc-binding protein compare
Pf1N1B4_5093 +0.6 1.2 Endo-beta-1,3-glucanase compare
Pf1N1B4_1154 +0.6 2.2 FIG00957702: hypothetical protein compare
Pf1N1B4_34 +0.6 0.9 Xanthine permease compare
Pf1N1B4_1675 +0.6 1.3 Transcriptional regulator compare
Pf1N1B4_4777 +0.6 1.9 Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) compare
Pf1N1B4_5082 +0.6 2.0 Capsular polysaccharide synthesis enzyme CpsB compare
Pf1N1B4_5596 +0.6 3.1 Putative hydroxycinnamate transporter compare
Pf1N1B4_4873 +0.6 1.8 clavaldehyde dehydrogenase compare
Pf1N1B4_4223 +0.6 1.4 Transcriptional regulator compare
Pf1N1B4_2269 +0.6 1.4 Purine nucleoside phosphorylase (EC 2.4.2.1) compare
Pf1N1B4_2357 +0.5 3.8 type IV pilus biogenesis protein PilJ compare
Pf1N1B4_18 +0.5 2.5 16 kDa heat shock protein A compare
Pf1N1B4_4376 +0.5 2.3 probable transmembrane protein compare
Pf1N1B4_4687 +0.5 3.1 Glycogen synthase, ADP-glucose transglucosylase (EC 2.4.1.21) compare
Pf1N1B4_855 +0.5 1.4 FIG021952: putative membrane protein compare
Pf1N1B4_695 +0.5 1.4 Aldehyde dehydrogenase (EC 1.2.1.3) compare
Pf1N1B4_4008 +0.5 2.2 Various polyols ABC transporter, ATP-binding component compare
Pf1N1B4_4132 +0.5 1.1 Mobile element protein compare
Pf1N1B4_817 +0.5 1.6 FIG00955104: hypothetical protein compare
Pf1N1B4_576 +0.5 1.8 hypothetical protein compare
Pf1N1B4_675 +0.5 1.3 hypothetical protein compare
Pf1N1B4_4001 +0.5 1.2 Membrane fusion component of tripartite multidrug resistance system compare
Pf1N1B4_561 +0.5 1.7 Glutathione S-transferase (EC 2.5.1.18) compare
Pf1N1B4_5907 +0.5 2.0 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases compare
Pf1N1B4_2420 +0.5 2.5 L-proline glycine betaine ABC transport system permease protein ProV (TC 3.A.1.12.1) compare
Pf1N1B4_21 +0.5 1.5 Probable hydrolase compare
Pf1N1B4_5979 +0.5 1.7 Ureidoglycolate/malate/sulfolactate dehydrogenase family (EC 1.1.1.-) compare
Pf1N1B4_1995 +0.5 2.0 FIG00954044: hypothetical protein compare
Pf1N1B4_5411 +0.5 1.9 hypothetical protein compare
Pf1N1B4_4551 +0.5 1.0 3-oxoacyl-[acyl-carrier-protein] synthase, KASII (EC 2.3.1.179) compare
Pf1N1B4_5962 +0.5 2.0 hypothetical protein compare
Pf1N1B4_4951 +0.5 1.3 Tryptophan synthase beta chain like (EC 4.2.1.20) compare
Pf1N1B4_2719 +0.5 4.2 Sensor histidine kinase compare
Pf1N1B4_5542 +0.5 1.1 hypothetical protein compare
Pf1N1B4_4246 +0.5 1.9 L-lactate permease compare
Pf1N1B4_5556 +0.5 1.5 hypothetical protein compare
Pf1N1B4_697 +0.5 1.9 Glycine cleavage system transcriptional activator compare
Pf1N1B4_5512 +0.5 0.6 hypothetical protein compare
Pf1N1B4_3811 +0.5 1.2 Hydantoin racemase (EC 5.1.99.-) compare
Pf1N1B4_5587 +0.5 2.9 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1; Vanillate O-demethylase oxidoreductase (EC 1.14.13.-) compare
Pf1N1B4_4408 +0.5 1.6 two-component response regulator compare
Pf1N1B4_2784 +0.5 1.2 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf1N1B4_2365 +0.5 2.5 Malonate decarboxylase gamma subunit compare
Pf1N1B4_5724 +0.5 1.4 High-affinity iron permease compare
Pf1N1B4_4470 +0.5 1.4 Cobalt-zinc-cadmium resistance protein CzcD compare
Pf1N1B4_731 +0.5 1.4 Scaffold protein for [4Fe-4S] cluster assembly ApbC, MRP-like compare
Pf1N1B4_68 +0.5 1.0 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) compare
Pf1N1B4_5843 +0.5 1.5 phospholipase/carboxylesterase family protein compare
Pf1N1B4_1583 +0.5 1.5 Histidine ABC transporter, ATP-binding protein (TC 3.A.1) compare
Pf1N1B4_1492 +0.5 0.9 FIG00959437: hypothetical protein compare
Pf1N1B4_4713 +0.5 2.1 Xanthine permease compare
Pf1N1B4_2364 +0.5 2.0 Malonate decarboxylase beta subunit compare
Pf1N1B4_6045 +0.5 1.3 CigR (Putative inner membrane protein) compare
Pf1N1B4_5786 +0.5 1.7 putative membrane protein compare
Pf1N1B4_2407 +0.5 2.2 FIG00953367: hypothetical protein compare
Pf1N1B4_1705 +0.5 1.7 SAM-dependent methyltransferases compare
Pf1N1B4_5448 +0.5 1.0 hypothetical protein compare
Pf1N1B4_1093 +0.5 1.8 FIG003879: Predicted amidohydrolase / Omega amidase (Nit2 homolog) compare
Pf1N1B4_1464 +0.5 3.1 Glycosyl transferase compare
Pf1N1B4_724 +0.5 1.4 DNA-binding response regulator ColR compare
Pf1N1B4_5647 +0.5 2.1 hypothetical protein compare
Pf1N1B4_3818 +0.5 1.1 Propionate catabolism operon transcriptional regulator of GntR family [predicted] compare
Pf1N1B4_4758 +0.5 1.6 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf1N1B4_122 +0.5 1.4 Inner membrane component of tripartite multidrug resistance system compare
Pf1N1B4_5078 +0.5 1.4 Transcriptional regulator PhnF compare
Pf1N1B4_439 +0.5 1.9 hypothetical protein compare
Pf1N1B4_2390 +0.5 1.5 probable membrane protein NMA1176 compare
Pf1N1B4_344 +0.5 1.7 hypothetical protein compare
Pf1N1B4_5286 +0.5 1.9 hypothetical protein compare
Pf1N1B4_1990 +0.4 2.4 GTP cyclohydrolase I (EC 3.5.4.16) type 2 compare
Pf1N1B4_1984 +0.4 1.9 Threonyl-tRNA synthetase (EC 6.1.1.3) compare
Pf1N1B4_5680 +0.4 1.6 DNA polymerase-like protein PA0670 compare
Pf1N1B4_2193 +0.4 1.0 hypothetical protein compare
Pf1N1B4_4587 +0.4 1.1 probable dioxygenase compare
Pf1N1B4_3719 +0.4 1.9 Glutathione peroxidase family protein compare
Pf1N1B4_5866 +0.4 1.8 ThiJ/PfpI family protein compare
Pf1N1B4_5790 +0.4 1.5 hypothetical protein compare
Pf1N1B4_5927 +0.4 4.1 Capsular polysaccharide biosynthesis protein compare
Pf1N1B4_676 +0.4 1.5 FIG00953991: hypothetical protein compare
Pf1N1B4_4268 +0.4 1.8 Mll5186 protein compare
Pf1N1B4_580 +0.4 1.4 FIG00953813: hypothetical protein compare
Pf1N1B4_5159 +0.4 1.8 Cellulose synthase operon protein C compare
Pf1N1B4_1496 +0.4 2.1 Na(+)/H(+) antiporter compare
Pf1N1B4_3461 +0.4 0.9 hypothetical protein compare
Pf1N1B4_1691 +0.4 0.6 hypothetical protein compare
Pf1N1B4_339 +0.4 1.2 UDP-glucose 4-epimerase (EC 5.1.3.2) compare
Pf1N1B4_286 +0.4 3.3 2-dehydropantoate 2-reductase (EC 1.1.1.169) compare
Pf1N1B4_3514 +0.4 3.6 Sensor histidine kinase/response regulator compare
Pf1N1B4_79 +0.4 1.9 Lactoylglutathione lyase and related lyases compare
Pf1N1B4_2635 +0.4 1.1 hypothetical protein compare
Pf1N1B4_3600 +0.4 2.2 Flagellar sensor histidine kinase FleS compare
Pf1N1B4_5868 +0.4 1.9 Secreted protein Hcp compare
Pf1N1B4_1886 +0.4 1.5 FIG00956005: hypothetical protein compare
Pf1N1B4_3637 +0.4 2.0 FlhB domain protein compare
Pf1N1B4_3368 +0.4 0.9 Allophanate hydrolase 2 subunit 2 (EC 3.5.1.54) compare
Pf1N1B4_177 +0.4 2.4 N-carbamoyl-L-amino acid hydrolase (EC 3.5.1.87) compare
Pf1N1B4_5063 +0.4 1.3 Phosphoribosyl transferase domain protein compare
Pf1N1B4_5797 +0.4 1.1 1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase (EC 1.3.1.25) compare
Pf1N1B4_1914 +0.4 2.1 Ribosomal RNA small subunit methyltransferase B (EC 2.1.1.-) compare
Pf1N1B4_5508 +0.4 1.0 hypothetical protein compare
Pf1N1B4_4331 +0.4 1.1 Transporter, LysE family compare
Pf1N1B4_3997 +0.4 1.3 Uncharacterized protein YtfM precursor compare
Pf1N1B4_4819 +0.4 2.1 Multidrug resistance protein B compare
Pf1N1B4_1298 +0.4 2.0 Putative Nudix hydrolase YfcD (EC 3.6.-.-) compare
Pf1N1B4_4817 +0.4 1.5 Fe2+-dicitrate sensor, membrane component compare
Pf1N1B4_623 +0.4 1.0 Aminomethyltransferase (glycine cleavage system T protein) (EC 2.1.2.10) compare


Specific Phenotypes

For 4 genes in this experiment

For carbon source Sodium D,L-Lactate in Pseudomonas fluorescens FW300-N1B4

For carbon source Sodium D,L-Lactate across organisms