Experiment set1IT017 for Pseudomonas fluorescens FW300-N2E2

Compare to:

m-Inositol carbon source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_64 -7.2 -4.9 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_5006 -6.6 -9.0 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_4077 -6.2 -4.2 cytosolic long-chain acyl-CoA thioester hydrolase family protein compare
Pf6N2E2_4597 -6.0 -11.5 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_77 -6.0 -5.8 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_4596 -5.9 -11.9 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_4825 -5.8 -10.5 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_3839 -5.7 -5.6 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_3253 -5.4 -9.0 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_3751 -5.3 -17.7 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_4071 -5.3 -6.2 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_4826 -5.2 -9.1 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_5175 -5.0 -18.2 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_5014 -4.9 -2.0 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_2753 -4.9 -4.8 HtrA protease/chaperone protein compare
Pf6N2E2_71 -4.9 -6.5 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_3610 -4.7 -8.2 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_4564 -4.7 -10.2 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_5176 -4.7 -14.0 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_5780 -4.5 -13.6 Periplasmic protease compare
Pf6N2E2_3630 -4.5 -8.0 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_5156 -4.4 -3.0 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_4279 -4.4 -14.0 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_3752 -4.4 -20.4 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_3782 -4.3 -6.6 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_4048 -4.2 -8.0 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_4047 -4.2 -8.5 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_1381 -4.1 -7.6 Aldehyde dehydrogenase (EC 1.2.1.3) compare
Pf6N2E2_5177 -4.1 -11.4 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_512 -4.0 -14.6 5-dehydro-2-deoxygluconokinase (EC 2.7.1.92); possible 5-dehydro-2-deoxyphosphogluconate aldolase DUF2090 (EC 4.1.2.29) (from data) conserved
Pf6N2E2_3783 -4.0 -7.6 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_523 -3.8 -13.0 Inositol transport system ATP-binding protein conserved
Pf6N2E2_4638 -3.8 -5.1 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_4278 -3.7 -14.0 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_3062 -3.7 -5.5 Membrane-associated zinc metalloprotease compare
Pf6N2E2_4418 -3.7 -1.4 Diaminopimelate epimerase (EC 5.1.1.7) compare
Pf6N2E2_3841 -3.6 -8.4 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_3271 -3.6 -3.9 Phosphocarrier protein, nitrogen regulation associated compare
Pf6N2E2_514 -3.6 -7.6 5-deoxy-D-glucuronate isomerase (EC 5.3.1.30) (from data) conserved
Pf6N2E2_516 -3.5 -6.5 Inosose isomerase (EC 5.3.99.-) conserved
Pf6N2E2_2258 -3.4 -13.0 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_3842 -3.4 -5.4 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_522 -3.4 -4.6 Inositol transport system sugar-binding protein compare
Pf6N2E2_1402 -3.4 -7.8 hypothetical protein compare
Pf6N2E2_2756 -3.4 -10.1 RNA polymerase sigma-H factor AlgT compare
Pf6N2E2_66 -3.3 -7.5 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_1401 -3.3 -10.2 FIG00955631: hypothetical protein compare
Pf6N2E2_524 -3.2 -9.6 Inositol transport system permease protein conserved
Pf6N2E2_4752 -3.2 -12.2 Malate synthase G (EC 2.3.3.9) compare
Pf6N2E2_3252 -3.1 -6.9 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_517 -3.1 -11.4 Epi-inositol hydrolase (EC 3.7.1.-) (from data) conserved
Pf6N2E2_4803 -3.0 -2.6 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_2574 -3.0 -4.3 Flagellar synthesis regulator FleN compare
Pf6N2E2_5255 -3.0 -11.3 Outer membrane stress sensor protease DegS compare
Pf6N2E2_1400 -3.0 -11.7 Sensory box histidine kinase/response regulator compare
Pf6N2E2_521 -3.0 -3.2 hypothetical protein compare
Pf6N2E2_3942 -2.9 -9.9 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
Pf6N2E2_2186 -2.9 -6.2 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
Pf6N2E2_5553 -2.9 -8.1 Quinolinate synthetase (EC 2.5.1.72) compare
Pf6N2E2_513 -2.9 -8.2 Myo-inosose-2 dehydratase (EC 4.2.1.44) (from data) conserved
Pf6N2E2_2217 -2.8 -7.4 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_518 -2.8 -6.9 Myo-inositol 2-dehydrogenase (EC 1.1.1.18) conserved
Pf6N2E2_5579 -2.8 -6.7 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_3940 -2.8 -11.0 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_1932 -2.8 -6.9 Transcriptional regulator, IclR family compare
Pf6N2E2_4759 -2.8 -15.2 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_5316 -2.7 -2.8 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_3346 -2.6 -7.0 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf6N2E2_302 -2.6 -7.7 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_63 -2.5 -4.5 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_4372 -2.5 -7.2 FIG00460773: hypothetical protein compare
Pf6N2E2_515 -2.5 -5.1 malonate-semialdehyde dehydrogenase (acetylating) (EC 1.2.1.18) (from data) conserved
Pf6N2E2_3460 -2.5 -2.7 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_3932 -2.5 -2.5 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_519 -2.4 -7.1 Myo-inositol 2-dehydrogenase (EC 1.1.1.18) compare
Pf6N2E2_6140 -2.4 -1.6 Large Subunit Ribosomal RNA; lsuRNA; LSU rRNA compare
Pf6N2E2_5178 -2.4 -2.7 CDP-diacylglycerol--serine O-phosphatidyltransferase (EC 2.7.8.8) compare
Pf6N2E2_3661 -2.4 -5.9 hypothetical protein compare
Pf6N2E2_5723 -2.3 -6.1 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
Pf6N2E2_4277 -2.3 -7.9 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_4416 -2.2 -4.2 Tyrosine recombinase XerC compare
Pf6N2E2_4204 -2.1 -2.5 rRNA small subunit 7-methylguanosine (m7G) methyltransferase GidB compare
Pf6N2E2_3248 -2.1 -6.5 Probable transmembrane protein compare
Pf6N2E2_2073 -2.1 -7.8 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_5252 -2.1 -3.3 FIG00956396: hypothetical protein compare
Pf6N2E2_2514 -2.1 -4.2 regulator of length of O-antigen component of lipopolysaccharide chains compare
Pf6N2E2_3258 -2.0 -6.0 Uncharacterized ABC transporter, periplasmic component YrbD compare
Pf6N2E2_4478 -1.9 -7.3 FIG019278: hypothetical protein compare
Pf6N2E2_4362 -1.9 -3.8 DNA-directed RNA polymerase omega subunit (EC 2.7.7.6) compare
Pf6N2E2_4160 -1.9 -1.8 Cytochrome c5 compare
Pf6N2E2_3984 -1.8 -9.1 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_5894 -1.8 -7.4 Putative threonine efflux protein compare
Pf6N2E2_4009 -1.8 -9.1 GGDEF domain protein compare
Pf6N2E2_180 -1.8 -4.0 Transcriptional regulator, MerR family compare
Pf6N2E2_5899 -1.8 -7.2 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system compare
Pf6N2E2_3170 -1.8 -4.3 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_5720 -1.8 -12.3 BarA sensory histidine kinase (= VarS = GacS) compare
Pf6N2E2_2074 -1.8 -1.6 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_2752 -1.8 -9.0 Exported zinc metalloprotease YfgC precursor compare
Pf6N2E2_2912 -1.7 -2.4 FIG00954094: hypothetical protein compare
Pf6N2E2_3835 -1.7 -4.5 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf6N2E2_3833 -1.6 -4.4 hypothetical protein compare
Pf6N2E2_3461 -1.6 -1.8 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_2022 -1.6 -6.7 BarA-associated response regulator UvrY (= GacA = SirA) compare
Pf6N2E2_5219 -1.6 -7.6 FIG140336: TPR domain protein compare
Pf6N2E2_2758 -1.5 -7.7 L-aspartate oxidase (EC 1.4.3.16) compare
Pf6N2E2_3941 -1.4 -1.8 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf6N2E2_5261 -1.4 -1.3 FIG00956983: hypothetical protein compare
Pf6N2E2_3260 -1.4 -5.0 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
Pf6N2E2_3134 -1.3 -1.2 hypothetical protein compare
Pf6N2E2_5001 -1.3 -1.9 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) compare
Pf6N2E2_50 -1.3 -5.8 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_5727 -1.3 -4.0 FIG00955360: hypothetical protein compare
Pf6N2E2_2508 -1.3 -2.9 hypothetical protein compare
Pf6N2E2_4352 -1.2 -3.2 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf6N2E2_3947 -1.2 -2.3 Cd(II)/Pb(II)-responsive transcriptional regulator compare
Pf6N2E2_1821 -1.2 -1.9 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system compare
Pf6N2E2_248 -1.2 -5.6 hypothetical protein compare
Pf6N2E2_5181 -1.2 -7.5 Paraquat-inducible protein A compare
Pf6N2E2_2869 -1.2 -1.7 Peptide deformylase (EC 3.5.1.88) compare
Pf6N2E2_5328 -1.2 -2.9 FIG00958649: hypothetical protein compare
Pf6N2E2_3240 -1.2 -1.7 Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) compare
Pf6N2E2_2261 -1.2 -6.3 VacJ-like lipoprotein precursor compare
Pf6N2E2_5150 -1.2 -4.3 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf6N2E2_622 -1.2 -3.4 BatA (Bacteroides aerotolerance operon) compare
Pf6N2E2_4817 -1.1 -9.0 Spermidine Putrescine ABC transporter permease component PotB (TC 3.A.1.11.1) compare
Pf6N2E2_282 -1.1 -2.0 GNAT family acetyltransferase YjcF compare
Pf6N2E2_2927 -1.1 -2.9 Putative signal peptide protein compare
Pf6N2E2_3060 -1.1 -2.8 Outer membrane protein H precursor compare
Pf6N2E2_2675 -1.1 -1.1 ATP-dependent RNA helicase SrmB compare
Pf6N2E2_5049 -1.1 -2.2 acetyltransferase, GNAT family compare
Pf6N2E2_70 -1.1 -3.2 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
Pf6N2E2_3257 -1.1 -3.1 Uncharacterized ABC transporter, auxiliary component YrbC compare
Pf6N2E2_2507 -1.1 -4.9 Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-) compare
Pf6N2E2_4994 -1.1 -4.4 Nicotinate-nucleotide adenylyltransferase (EC 2.7.7.18) compare
Pf6N2E2_2549 -1.1 -1.5 hypothetical protein compare
Pf6N2E2_3021 -1.1 -1.3 hypothetical protein compare
Pf6N2E2_98 -1.1 -1.8 putative transmembrane protein compare
Pf6N2E2_5086 -1.0 -1.3 hypothetical protein compare
Pf6N2E2_1040 -1.0 -1.9 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
Pf6N2E2_2010 -1.0 -1.8 hypothetical protein compare
Pf6N2E2_922 -1.0 -3.0 FIG00794167: hypothetical protein compare
Pf6N2E2_5728 -1.0 -2.7 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_1783 -1.0 -2.2 Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY compare
Pf6N2E2_5183 -1.0 -7.5 Paraquat-inducible protein B compare
Pf6N2E2_288 -1.0 -1.7 Isocitrate dehydrogenase [NADP] (EC 1.1.1.42); Monomeric isocitrate dehydrogenase [NADP] (EC 1.1.1.42) compare
Pf6N2E2_2438 -1.0 -1.7 hypothetical protein compare
Pf6N2E2_5739 -1.0 -1.1 Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family compare
Pf6N2E2_746 -1.0 -1.7 FIG00958097: hypothetical protein compare
Pf6N2E2_5342 -1.0 -2.1 21 kDa hemolysin precursor compare
Pf6N2E2_623 -1.0 -1.2 FIG00954674: hypothetical protein compare
Pf6N2E2_3613 -1.0 -4.6 GTP-binding protein HflX compare
Pf6N2E2_4611 -1.0 -2.9 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_621 -1.0 -5.3 TPR domain protein in aerotolerance operon compare
Pf6N2E2_4479 -0.9 -2.2 FIG001590: Putative conserved exported protein precursor compare
Pf6N2E2_4059 -0.9 -1.0 DNA-binding protein HU-alpha compare
Pf6N2E2_3132 -0.9 -2.5 FIG00954548: hypothetical protein compare
Pf6N2E2_5943 -0.9 -0.8 hypothetical protein compare
Pf6N2E2_4494 -0.9 -2.8 Adenylate cyclase (EC 4.6.1.1) compare
Pf6N2E2_3692 -0.9 -7.1 Selenoprotein O and cysteine-containing homologs compare
Pf6N2E2_1339 -0.9 -2.5 Acetylornithine deacetylase (EC 3.5.1.16) compare
Pf6N2E2_3192 -0.9 -2.9 tRNA:Cm32/Um32 methyltransferase compare
Pf6N2E2_2013 -0.9 -1.1 hypothetical protein compare
Pf6N2E2_4480 -0.9 -6.4 Xaa-Pro aminopeptidase (EC 3.4.11.9) compare
Pf6N2E2_5609 -0.9 -3.3 DNA-binding response regulator ColR compare
Pf6N2E2_2487 -0.9 -0.9 FIG00956090: hypothetical protein compare
Pf6N2E2_3255 -0.8 -2.8 YrbA protein compare
Pf6N2E2_2218 -0.8 -2.9 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_504 -0.8 -1.6 DNA-binding response regulator compare
Pf6N2E2_5556 -0.8 -4.1 Aminomethyltransferase (EC 2.1.2.10) (from data) compare
Pf6N2E2_4206 -0.8 -1.5 Chromosome (plasmid) partitioning protein ParB compare
Pf6N2E2_2277 -0.8 -1.5 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_5610 -0.8 -4.1 two-component system sensor protein compare
Pf6N2E2_2390 -0.8 -1.9 FIG00959101: hypothetical protein compare
Pf6N2E2_4162 -0.8 -1.8 DNA polymerase I (EC 2.7.7.7) compare
Pf6N2E2_2367 -0.8 -1.9 hypothetical protein compare
Pf6N2E2_2119 -0.8 -2.2 hypothetical protein compare
Pf6N2E2_3834 -0.8 -2.9 Lipoprotein NlpD compare
Pf6N2E2_904 -0.8 -2.5 hypothetical protein compare
Pf6N2E2_1705 -0.8 -1.3 Branched-chain amino acid transport ATP-binding protein LivG (TC 3.A.1.4.1) compare
Pf6N2E2_1838 -0.8 -2.1 6-hexanolactone hydrolase compare
Pf6N2E2_5345 -0.8 -4.5 LppC putative lipoprotein compare
Pf6N2E2_6065 -0.8 -1.5 ABC transporter in pyoverdin gene cluster, periplasmic component compare
Pf6N2E2_338 -0.8 -1.4 Transcriptional regulator, AraC family compare
Pf6N2E2_5794 -0.8 -1.4 Ribosomal large subunit pseudouridine synthase A (EC 4.2.1.70) compare
Pf6N2E2_395 -0.7 -2.5 Glutathione S-transferase (EC 2.5.1.18) compare
Pf6N2E2_5772 -0.7 -2.7 DUF1232 domain-containing protein compare
Pf6N2E2_238 -0.7 -1.6 hypothetical protein compare
Pf6N2E2_5182 -0.7 -3.8 Paraquat-inducible protein A compare
Pf6N2E2_1298 -0.7 -3.0 Xanthine transporter,putative compare
Pf6N2E2_3557 -0.7 -2.1 Chaperone-modulator protein CbpM compare
Pf6N2E2_384 -0.7 -1.1 Glycine cleavage system transcriptional activator compare
Pf6N2E2_5128 -0.7 -2.7 COG1496: Uncharacterized conserved protein compare
Pf6N2E2_1501 -0.7 -2.6 Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) (EC 3.6.1.17) compare
Pf6N2E2_4485 -0.7 -4.0 Aminomethyltransferase (glycine cleavage system T protein) (EC 2.1.2.10) compare
Pf6N2E2_2885 -0.7 -2.8 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) compare
Pf6N2E2_5994 -0.7 -2.8 Superfamily II DNA/RNA helicases, SNF2 family compare
Pf6N2E2_5704 -0.7 -4.1 Transcriptional regulatory protein PhoP compare
Pf6N2E2_4993 -0.7 -1.4 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) compare
Pf6N2E2_2992 -0.7 -2.4 Regulatory protein RecX compare


Specific Phenotypes

For 25 genes in this experiment

For carbon source m-Inositol in Pseudomonas fluorescens FW300-N2E2

For carbon source m-Inositol across organisms