Experiment set1IT016 for Pseudomonas fluorescens FW300-N1B4

Compare to:

Sodium D-Lactate carbon source

200 most important genes:

  gene name fitness t score description  
Pf1N1B4_15 -3.8 -3.7 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf1N1B4_1831 -3.8 -11.7 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf1N1B4_6 -3.7 -5.6 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf1N1B4_1307 -3.7 -2.5 3-dehydroquinate dehydratase II (EC 4.2.1.10) compare
Pf1N1B4_5666 -3.6 -3.5 Oxidoreductase probably involved in sulfite reduction compare
Pf1N1B4_1189 -3.5 -4.8 Predicted L-lactate dehydrogenase, hypothetical protein subunit YkgG compare
Pf1N1B4_2272 -3.5 -3.4 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf1N1B4_742 -3.5 -7.1 Argininosuccinate synthase (EC 6.3.4.5) compare
Pf1N1B4_1533 -3.5 -7.1 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf1N1B4_3812 -3.4 -7.9 Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) compare
Pf1N1B4_1534 -3.4 -18.1 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf1N1B4_1624 -3.4 -8.2 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf1N1B4_1872 -3.3 -6.4 Zinc ABC transporter, periplasmic-binding protein ZnuA compare
Pf1N1B4_1626 -3.3 -7.0 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf1N1B4_1408 -3.3 -5.0 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf1N1B4_1565 -3.3 -4.5 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf1N1B4_2303 -3.3 -14.6 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf1N1B4_3506 -3.3 -8.1 Cysteine synthase B (EC 2.5.1.47) compare
Pf1N1B4_2880 -3.3 -12.8 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf1N1B4_1870 -3.3 -3.1 Zinc ABC transporter, ATP-binding protein ZnuC compare
Pf1N1B4_1067 -3.2 -6.2 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf1N1B4_2682 -3.2 -3.1 Antiholin-like protein LrgA compare
Pf1N1B4_1869 -3.2 -7.1 Zinc ABC transporter, inner membrane permease protein ZnuB compare
Pf1N1B4_2545 -3.2 -13.1 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
Pf1N1B4_1627 -3.2 -5.3 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf1N1B4_1188 -3.2 -10.6 Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF conserved
Pf1N1B4_2548 -3.1 -7.2 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf1N1B4_2283 -3.1 -1.8 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf1N1B4_2549 -3.1 -9.8 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf1N1B4_2683 -3.1 -6.2 LrgA-associated membrane protein LrgB conserved
Pf1N1B4_3697 -3.1 -8.9 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf1N1B4_2858 -3.1 -10.9 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf1N1B4_1190 -3.0 -10.2 Predicted D-lactate dehydrogenase, Fe-S protein, FAD/FMN-containing conserved
Pf1N1B4_12 -3.0 -7.1 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf1N1B4_275 -3.0 -2.8 Organic hydroperoxide resistance transcriptional regulator compare
Pf1N1B4_2384 -3.0 -10.0 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf1N1B4_1434 -3.0 -8.3 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf1N1B4_1315 -3.0 -8.8 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) compare
Pf1N1B4_2338 -3.0 -7.6 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf1N1B4_2009 -2.9 -5.6 LysR family transcriptional regulator PA5437 compare
Pf1N1B4_1830 -2.9 -8.9 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf1N1B4_5665 -2.9 -5.8 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf1N1B4_2010 -2.9 -6.4 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf1N1B4_1186 -2.8 -10.4 L-lactate permease conserved
Pf1N1B4_1113 -2.8 -5.9 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf1N1B4_4065 -2.7 -8.6 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf1N1B4_762 -2.6 -6.3 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf1N1B4_1668 -2.6 -5.8 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
Pf1N1B4_365 -2.6 -6.5 Cell division protein BolA compare
Pf1N1B4_350 -2.6 -7.3 Chorismate mutase I (EC 5.4.99.5) / Prephenate dehydratase (EC 4.2.1.51) compare
Pf1N1B4_327 -2.6 -2.9 hypothetical protein compare
Pf1N1B4_1187 -2.6 -6.9 Predicted L-lactate dehydrogenase, Fe-S oxidoreductase subunit YkgE conserved
Pf1N1B4_2547 -2.5 -3.4 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
Pf1N1B4_1617 -2.5 -8.4 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (EC 5.4.2.1) compare
Pf1N1B4_3368 -2.5 -2.9 Allophanate hydrolase 2 subunit 2 (EC 3.5.1.54) compare
Pf1N1B4_257 -2.5 -6.5 sensor histidine kinase/response regulator compare
Pf1N1B4_769 -2.5 -7.0 Aerobic glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) compare
Pf1N1B4_2879 -2.5 -7.8 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf1N1B4_2878 -2.4 -8.5 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf1N1B4_847 -2.4 -9.2 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf1N1B4_2337 -2.3 -5.5 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf1N1B4_2176 -2.3 -2.8 Frataxin homolog CyaY, facilitates iron supply for heme A synthesis or Fe-S cluster assembly compare
Pf1N1B4_1057 -2.3 -3.7 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf1N1B4_2011 -2.3 -8.4 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf1N1B4_2282 -2.3 -9.1 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf1N1B4_1568 -2.2 -3.6 Twin-arginine translocation protein TatB compare
Pf1N1B4_1906 -2.2 -3.8 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) compare
Pf1N1B4_1653 -2.2 -7.7 Branched-chain amino acid transport protein AzlC compare
Pf1N1B4_1625 -2.1 -4.1 FIG00956267: hypothetical protein compare
Pf1N1B4_3917 -2.1 -4.9 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf1N1B4_2112 -2.0 -12.5 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
Pf1N1B4_722 -2.0 -2.4 SAM-dependent methyltransferases compare
Pf1N1B4_652 -2.0 -8.8 Sensory box histidine kinase compare
Pf1N1B4_2526 -2.0 -13.5 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf1N1B4_3878 -2.0 -7.4 Cytochrome c oxidase subunit CcoO (EC 1.9.3.1) compare
Pf1N1B4_2859 -1.9 -12.8 Two-component sensor CbrA: intrcellular carbon:nitrogen balance compare
Pf1N1B4_3081 -1.9 -14.8 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
Pf1N1B4_3876 -1.8 -7.5 Cytochrome c oxidase subunit CcoP (EC 1.9.3.1) compare
Pf1N1B4_952 -1.8 -3.2 Cell division protein MraZ compare
Pf1N1B4_4957 -1.8 -2.4 Transcriptional regulator, TetR family compare
Pf1N1B4_960 -1.8 -9.1 ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit compare
Pf1N1B4_4715 -1.7 -2.2 Transcriptional regulator compare
Pf1N1B4_961 -1.7 -12.1 Ubiquinol--cytochrome c reductase, cytochrome B subunit (EC 1.10.2.2) compare
Pf1N1B4_1590 -1.7 -5.8 Histidine utilization repressor compare
Pf1N1B4_3518 -1.7 -3.0 Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) compare
Pf1N1B4_3879 -1.7 -11.3 Cytochrome c oxidase subunit CcoN (EC 1.9.3.1) compare
Pf1N1B4_1569 -1.7 -10.4 Twin-arginine translocation protein TatC compare
Pf1N1B4_962 -1.7 -8.6 Ubiquinol-cytochrome C reductase iron-sulfur subunit (EC 1.10.2.2) compare
Pf1N1B4_1159 -1.6 -3.3 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
Pf1N1B4_578 -1.6 -2.5 enoyl-CoA hydratase, R-specific compare
Pf1N1B4_2228 -1.6 -3.9 FIG001590: Putative conserved exported protein precursor compare
Pf1N1B4_5014 -1.6 -2.7 Glutathione reductase (EC 1.8.1.7) compare
Pf1N1B4_1052 -1.6 -2.5 FKBP-type peptidyl-prolyl cis-trans isomerase SlyD (EC 5.2.1.8) compare
Pf1N1B4_1566 -1.5 -5.9 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf1N1B4_5242 -1.5 -1.7 hypothetical protein compare
Pf1N1B4_3869 -1.4 -9.2 Heavy-metal-associated domain (N-terminus) and membrane-bounded cytochrome biogenesis cycZ-like domain, possible membrane copper tolerance protein compare
Pf1N1B4_3870 -1.4 -10.4 Type cbb3 cytochrome oxidase biogenesis protein CcoS, involved in heme b insertion compare
Pf1N1B4_5815 -1.4 -3.3 diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) compare
Pf1N1B4_1317 -1.3 -2.5 Sensor histidine kinase/response regulator compare
Pf1N1B4_4857 -1.3 -4.1 Chemotaxis protein methyltransferase CheR (EC 2.1.1.80) compare
Pf1N1B4_4494 -1.3 -3.4 hypothetical protein compare
Pf1N1B4_1878 -1.3 -7.3 Cytochrome c4 compare
Pf1N1B4_3880 -1.3 -8.2 hypothetical protein compare
Pf1N1B4_4939 -1.3 -3.3 sodium/hydrogen exchanger family protein compare
Pf1N1B4_2280 -1.3 -6.5 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf1N1B4_3871 -1.3 -8.9 Type cbb3 cytochrome oxidase biogenesis protein CcoI; Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf1N1B4_1 -1.3 -2.0 Colicin V production protein compare
Pf1N1B4_3849 -1.2 -3.2 Transcriptional regulator, GntR family compare
Pf1N1B4_4755 -1.2 -2.2 ribosomal protein S6 glutaminyl transferase related protein compare
Pf1N1B4_4218 -1.2 -3.1 Multidrug resistance protein A compare
Pf1N1B4_5863 -1.2 -2.6 Glycolate dehydrogenase (EC 1.1.99.14), FAD-binding subunit GlcE compare
Pf1N1B4_5425 -1.2 -1.8 DNA-binding protein HU-beta compare
Pf1N1B4_5658 -1.2 -3.7 Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) compare
Pf1N1B4_1535 -1.2 -2.7 hypothetical protein compare
Pf1N1B4_702 -1.2 -3.8 Transcriptional regulator PobR, AraC family compare
Pf1N1B4_3038 -1.1 -3.6 Chemotaxis response regulator protein-glutamate methylesterase CheB (EC 3.1.1.61) compare
Pf1N1B4_3325 -1.1 -2.1 Sigma factor RpoE negative regulatory protein RseB precursor compare
Pf1N1B4_4980 -1.1 -2.0 putative lipoprotein compare
Pf1N1B4_1180 -1.1 -2.1 Outer membrane lipoprotein SmpA, a component of the essential YaeT outer-membrane protein assembly complex compare
Pf1N1B4_1279 -1.1 -2.1 Flp pilus assembly protein TadB compare
Pf1N1B4_2870 -1.1 -2.0 Regulator of competence-specific genes compare
Pf1N1B4_5862 -1.1 -3.6 Glycolate dehydrogenase (EC 1.1.99.14), subunit GlcD compare
Pf1N1B4_2491 -1.1 -3.0 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf1N1B4_4835 -1.1 -2.2 Carbon starvation protein A compare
Pf1N1B4_1236 -1.1 -4.8 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf1N1B4_3356 -1.1 -1.9 Cyclic nucleotide-binding protein compare
Pf1N1B4_4596 -1.1 -2.4 Hydroxyacylglutathione hydrolase (EC 3.1.2.6) compare
Pf1N1B4_2489 -1.1 -3.0 Biotin synthesis protein BioH compare
Pf1N1B4_5512 -1.1 -1.6 hypothetical protein compare
Pf1N1B4_3494 -1.1 -2.6 Flavoprotein WrbA compare
Pf1N1B4_3872 -1.1 -5.9 Putative analog of CcoH, COG3198 compare
Pf1N1B4_3993 -1.1 -3.1 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
Pf1N1B4_7 -1.0 -3.6 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
Pf1N1B4_5591 -1.0 -2.0 Vanillin dehydrogenase (Hydroxybenzaldehyde dehydrogenase) (EC 1.2.1.28) compare
Pf1N1B4_366 -1.0 -4.5 FIG00954136: hypothetical protein compare
Pf1N1B4_3415 -1.0 -3.1 Transcriptional regulator, TetR family compare
Pf1N1B4_3647 -1.0 -6.5 Cytochrome c heme lyase subunit CcmH compare
Pf1N1B4_2352 -1.0 -4.3 Glutathione synthetase (EC 6.3.2.3) compare
Pf1N1B4_358 -1.0 -4.7 Oxidoreductase, short chain dehydrogenase/reductase family compare
Pf1N1B4_5561 -1.0 -2.3 hypothetical protein compare
Pf1N1B4_2184 -1.0 -4.5 Autolysis response regulater LytR compare
Pf1N1B4_4870 -1.0 -1.5 Isoquinoline 1-oxidoreductase alpha subunit (EC 1.3.99.16) compare
Pf1N1B4_3665 -1.0 -2.4 Transcriptional regulator, TetR family compare
Pf1N1B4_4797 -1.0 -2.4 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf1N1B4_348 -1.0 -2.4 Cyclohexadienyl dehydrogenase (EC 1.3.1.12)(EC 1.3.1.43) / 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19) compare
Pf1N1B4_1294 -1.0 -2.0 VgrG protein compare
Pf1N1B4_2949 -1.0 -2.0 FIG00956396: hypothetical protein compare
Pf1N1B4_1554 -1.0 -4.7 predicted FeS cluster maintenance protein (from data) compare
Pf1N1B4_1652 -1.0 -5.4 transcriptional regulator, LysR family compare
Pf1N1B4_4123 -1.0 -1.0 Isochorismate pyruvate-lyase (EC 4.-.-.-) compare
Pf1N1B4_5311 -1.0 -1.5 hypothetical protein compare
Pf1N1B4_1975 -1.0 -1.8 Transcriptional regulator, AsnC family compare
Pf1N1B4_4929 -1.0 -2.1 Opine oxidase subunit B compare
Pf1N1B4_27 -0.9 -3.3 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf1N1B4_440 -0.9 -3.0 hypothetical protein compare
Pf1N1B4_2377 -0.9 -4.4 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf1N1B4_2541 -0.9 -3.8 Spermidine Putrescine ABC transporter permease component potC (TC_3.A.1.11.1) compare
Pf1N1B4_2568 -0.9 -2.2 Translation elongation factor Tu compare
Pf1N1B4_2173 -0.9 -1.9 Diaminopimelate epimerase (EC 5.1.1.7) compare
Pf1N1B4_1827 -0.9 -2.8 FIG00953482: hypothetical protein compare
Pf1N1B4_1993 -0.9 -1.4 C4-type zinc finger protein, DksA/TraR family compare
Pf1N1B4_4851 -0.9 -1.5 Transcriptional regulator of various polyols utilization, AraC family compare
Pf1N1B4_262 -0.9 -7.5 Probable protease htpX homolog (EC 3.4.24.-) compare
Pf1N1B4_241 -0.9 -1.7 Thiol-disulfide isomerase and thioredoxins compare
Pf1N1B4_5659 -0.9 -5.7 NfuA Fe-S protein maturation compare
Pf1N1B4_5972 -0.9 -1.9 Ribose ABC transport system, permease protein RbsC (TC 3.A.1.2.1) compare
Pf1N1B4_2171 -0.9 -2.4 Tyrosine recombinase XerC compare
Pf1N1B4_5508 -0.9 -1.5 hypothetical protein compare
Pf1N1B4_932 -0.9 -1.2 FIG00963370: hypothetical protein compare
Pf1N1B4_4527 -0.9 -2.0 Short-chain dehydrogenase/reductase SDR compare
Pf1N1B4_3153 -0.9 -1.5 hypothetical protein compare
Pf1N1B4_2856 -0.9 -2.8 Poly(A) polymerase (EC 2.7.7.19) compare
Pf1N1B4_3468 -0.9 -1.5 Negative regulator of flagellin synthesis FlgM compare
Pf1N1B4_5724 -0.9 -1.8 High-affinity iron permease compare
Pf1N1B4_2144 -0.9 -4.5 D-amino acid dehydrogenase small subunit (EC 1.4.99.1) compare
Pf1N1B4_2867 -0.9 -2.9 Hemin ABC transporter, permease protein compare
Pf1N1B4_5995 -0.9 -1.5 Transporter, MFS superfamily compare
Pf1N1B4_4429 -0.9 -1.5 No significant database matches compare
Pf1N1B4_4601 -0.8 -2.2 Streptothricin acetyltransferase, Streptomyces lavendulae type compare
Pf1N1B4_58 -0.8 -3.7 Transaldolase (EC 2.2.1.2) compare
Pf1N1B4_866 -0.8 -1.4 Iron-sulfur cluster regulator IscR compare
Pf1N1B4_3729 -0.8 -1.6 Quaternary ammonium compound-resistance protein SugE compare
Pf1N1B4_3742 -0.8 -1.7 Oxidoreductase, zinc-binding compare
Pf1N1B4_22 -0.8 -3.2 Transcriptional regulator, TetR family compare
Pf1N1B4_324 -0.8 -1.6 Glycosyl transferase, group 2 family protein compare
Pf1N1B4_133 -0.8 -2.0 Sigma-70 factor FpvI (ECF subfamily), controling pyoverdin biosynthesis compare
Pf1N1B4_1042 -0.8 -1.8 Dihydroneopterin triphosphate epimerase compare
Pf1N1B4_718 -0.8 -3.8 outer membrane component of uptake system, probably for ferrous iron (from data) compare
Pf1N1B4_2005 -0.8 -1.0 ATP-dependent DNA helicase UvrD/PcrA compare
Pf1N1B4_2334 -0.8 -2.2 Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB compare
Pf1N1B4_602 -0.8 -2.1 NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) compare
Pf1N1B4_2487 -0.8 -4.3 Biotin synthase (EC 2.8.1.6) compare
Pf1N1B4_3328 -0.8 -1.1 Rhodanese-like domain protein compare
Pf1N1B4_644 -0.8 -1.3 Cold shock protein CspC compare
Pf1N1B4_5137 -0.8 -3.8 Carboxynorspermidine decarboxylase, putative (EC 4.1.1.-) compare
Pf1N1B4_4027 -0.8 -1.5 hypothetical protein compare
Pf1N1B4_13 -0.8 -2.0 SAM-dependent methyltransferase YafE (UbiE paralog) compare
Pf1N1B4_4004 -0.8 -1.5 Peptidyl-prolyl cis-trans isomerase PpiB (EC 5.2.1.8) compare
Pf1N1B4_2225 -0.8 -5.2 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) compare
Pf1N1B4_6028 -0.8 -2.4 FIG00954052: hypothetical protein compare


Specific Phenotypes

For 6 genes in this experiment

For carbon source Sodium D-Lactate in Pseudomonas fluorescens FW300-N1B4

For carbon source Sodium D-Lactate across organisms