Experiment set1IT016 for Pseudomonas fluorescens FW300-N1B4

Compare to:

Sodium D-Lactate carbon source

200 most detrimental genes:

  gene name fitness t score description  
Pf1N1B4_2114 +1.6 10.6 DNA-directed RNA polymerase omega subunit (EC 2.7.7.6) compare
Pf1N1B4_2284 +1.6 8.5 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
Pf1N1B4_2060 +1.3 3.8 hypothetical protein compare
Pf1N1B4_3501 +1.3 7.5 BarA sensory histidine kinase (= VarS = GacS) compare
Pf1N1B4_4509 +1.3 2.4 Aldose 1-epimerase compare
Pf1N1B4_290 +1.2 11.6 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf1N1B4_919 +1.2 3.9 hypothetical protein compare
Pf1N1B4_740 +1.1 2.2 Leucyl-tRNA synthetase compare
Pf1N1B4_1185 +1.1 6.3 Lactate-responsive regulator LldR in Enterobacteria, GntR family compare
Pf1N1B4_3115 +1.1 7.3 RNA polymerase sigma factor RpoS compare
Pf1N1B4_507 +1.0 1.9 FIG00956448: hypothetical protein compare
Pf1N1B4_2401 +1.0 2.0 Lipoprotein, putative compare
Pf1N1B4_188 +1.0 2.1 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf1N1B4_4855 +1.0 3.2 Response regulator compare
Pf1N1B4_855 +1.0 2.8 FIG021952: putative membrane protein compare
Pf1N1B4_5224 +1.0 3.4 tRNA-Arg-CCT compare
Pf1N1B4_695 +1.0 2.8 Aldehyde dehydrogenase (EC 1.2.1.3) compare
Pf1N1B4_4422 +0.9 2.1 ABC transporter amino acid-binding protein compare
Pf1N1B4_218 +0.9 6.3 Periplasmic binding protein compare
Pf1N1B4_2853 +0.9 2.1 Pantoate--beta-alanine ligase (EC 6.3.2.1) compare
Pf1N1B4_68 +0.9 2.7 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) compare
Pf1N1B4_3408 +0.9 2.2 Transcriptional regulator, AraC family compare
Pf1N1B4_5249 +0.9 2.9 Outer membrane protein A precursor compare
Pf1N1B4_1105 +0.9 2.1 4-carboxymuconolactone decarboxylase (EC 4.1.1.44) compare
Pf1N1B4_4644 +0.9 2.2 hypothetical protein compare
Pf1N1B4_1475 +0.9 4.3 FIG00962376: hypothetical protein compare
Pf1N1B4_2969 +0.9 7.2 ATPase, AFG1 family compare
Pf1N1B4_3126 +0.8 2.8 Phage tail length tape-measure protein compare
Pf1N1B4_5055 +0.8 3.1 (R)-3-hydroxydecanoyl-ACP:CoA transacylase PhaG (3-hydroxyacyl-CoA-acyl carrier protein transferase) (EC 2.4.1.-) compare
Pf1N1B4_5356 +0.8 2.7 hypothetical protein compare
Pf1N1B4_4054 +0.8 4.6 ATP-dependent Clp protease adaptor protein ClpS compare
Pf1N1B4_4001 +0.8 1.9 Membrane fusion component of tripartite multidrug resistance system compare
Pf1N1B4_2975 +0.8 1.7 Peptide methionine sulfoxide reductase MsrB (EC 1.8.4.12) compare
Pf1N1B4_4951 +0.8 2.6 Tryptophan synthase beta chain like (EC 4.2.1.20) compare
Pf1N1B4_1899 +0.8 3.3 Gfa-like protein compare
Pf1N1B4_676 +0.8 2.8 FIG00953991: hypothetical protein compare
Pf1N1B4_2621 +0.8 1.8 PspA/IM30 family protein compare
Pf1N1B4_5294 +0.8 1.2 hypothetical protein compare
Pf1N1B4_2851 +0.8 1.2 hypothetical protein compare
Pf1N1B4_4918 +0.8 1.5 Predicted enzyme of the cupin superfamily compare
Pf1N1B4_1461 +0.8 3.0 Protein fixF compare
Pf1N1B4_2465 +0.8 2.1 Two-component response regulator CreB compare
Pf1N1B4_675 +0.8 2.6 hypothetical protein compare
Pf1N1B4_288 +0.7 5.0 FIG00958794: hypothetical protein compare
Pf1N1B4_5077 +0.7 2.0 D-beta-hydroxybutyrate dehydrogenase (EC 1.1.1.30) compare
Pf1N1B4_2891 +0.7 2.7 Ribosomal-protein-S18p-alanine acetyltransferase (EC 2.3.1.-) compare
Pf1N1B4_4057 +0.7 4.0 Arginine-tRNA-protein transferase (EC 2.3.2.8) compare
Pf1N1B4_3492 +0.7 2.4 DNA-3-methyladenine glycosylase (EC 3.2.2.20) compare
Pf1N1B4_1557 +0.7 5.8 Polyhydroxyalkanoic acid synthase compare
Pf1N1B4_725 +0.7 3.1 PAP2 superfamily protein compare
Pf1N1B4_287 +0.7 3.9 Possible periplasmic thiredoxin compare
Pf1N1B4_5408 +0.7 2.4 hypothetical protein compare
Pf1N1B4_4531 +0.7 1.5 FIG01221261: hypothetical protein compare
Pf1N1B4_1888 +0.7 3.1 Glutamate-aspartate carrier protein compare
Pf1N1B4_3047 +0.7 2.8 Putative lipoprotein in cluster with COG2110 compare
Pf1N1B4_2357 +0.7 4.5 type IV pilus biogenesis protein PilJ compare
Pf1N1B4_3547 +0.7 1.5 DNA-binding response regulator compare
Pf1N1B4_6045 +0.7 1.9 CigR (Putative inner membrane protein) compare
Pf1N1B4_3141 +0.7 1.3 FIG00959768: hypothetical protein compare
Pf1N1B4_5089 +0.7 2.5 Exopolysaccharide production protein ExoQ compare
Pf1N1B4_817 +0.7 2.3 FIG00955104: hypothetical protein compare
Pf1N1B4_5301 +0.7 2.9 hypothetical protein compare
Pf1N1B4_4007 +0.7 1.9 sigma-54 dependent transcriptional regulator compare
Pf1N1B4_1127 +0.6 3.9 Dipeptide transport ATP-binding protein DppF (TC 3.A.1.5.2) compare
Pf1N1B4_3065 +0.6 2.4 FIG00954412: hypothetical protein compare
Pf1N1B4_5542 +0.6 1.5 hypothetical protein compare
Pf1N1B4_4194 +0.6 2.2 2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34) compare
Pf1N1B4_3865 +0.6 2.0 Butyryl-CoA dehydrogenase (EC 1.3.99.2) compare
Pf1N1B4_4687 +0.6 3.4 Glycogen synthase, ADP-glucose transglucosylase (EC 2.4.1.21) compare
Pf1N1B4_4250 +0.6 1.6 Methyltransferase (EC 2.1.1.-) compare
Pf1N1B4_5519 +0.6 1.9 hypothetical protein compare
Pf1N1B4_2814 +0.6 2.7 Type IV fimbrial biogenesis protein PilX compare
Pf1N1B4_3836 +0.6 1.8 Nitrite reductase [NAD(P)H] small subunit (EC 1.7.1.4) compare
Pf1N1B4_2314 +0.6 1.5 FIG028932: hypothetical protein compare
Pf1N1B4_5406 +0.6 1.9 hypothetical protein compare
Pf1N1B4_875 +0.6 1.7 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf1N1B4_5498 +0.6 1.2 hypothetical protein compare
Pf1N1B4_516 +0.6 1.9 Sensor histidine kinase compare
Pf1N1B4_1670 +0.6 2.5 FIG001957: putative hydrolase compare
Pf1N1B4_5255 +0.6 1.2 hypothetical protein compare
Pf1N1B4_2854 +0.6 2.8 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) compare
Pf1N1B4_2507 +0.6 1.9 hypothetical protein compare
Pf1N1B4_2455 +0.6 2.0 Sarcosine oxidase beta subunit (EC 1.5.3.1) compare
Pf1N1B4_3967 +0.6 2.6 AFG1-like ATPase compare
Pf1N1B4_3859 +0.6 3.0 Transcriptional regulator, Cro/CI family compare
Pf1N1B4_5013 +0.6 1.7 Cointegrate resolution protein T compare
Pf1N1B4_2776 +0.6 1.8 Transcriptional regulator, GntR family compare
Pf1N1B4_4505 +0.6 1.7 Coenzyme PQQ synthesis protein E compare
Pf1N1B4_5568 +0.6 1.4 hypothetical protein compare
Pf1N1B4_483 +0.6 1.0 Metal-dependent hydrolase related to alanyl-tRNA synthetase compare
Pf1N1B4_615 +0.6 1.6 Arginine deiminase (EC 3.5.3.6) compare
Pf1N1B4_4860 +0.6 1.7 Sensory box sensor histidine kinase/response regulator (EC 2.7.3.-) compare
Pf1N1B4_1411 +0.6 2.2 GTP-binding protein HflX compare
Pf1N1B4_5451 +0.6 1.6 hypothetical protein compare
Pf1N1B4_4756 +0.6 2.1 Magnesium and cobalt transport protein CorA compare
Pf1N1B4_1707 +0.6 2.1 Efflux membrane fusion protein, RND family compare
Pf1N1B4_1265 +0.6 3.5 FIG00956297: hypothetical protein compare
Pf1N1B4_4568 +0.6 1.2 FIG00793915: hypothetical protein compare
Pf1N1B4_122 +0.6 1.8 Inner membrane component of tripartite multidrug resistance system compare
Pf1N1B4_3670 +0.6 2.0 probable glucosyl transferase compare
Pf1N1B4_2355 +0.6 2.4 type IV pili signal transduction protein PilI compare
Pf1N1B4_825 +0.6 1.4 tRNA (uridine-5-oxyacetic acid methyl ester) 34 synthase compare
Pf1N1B4_4417 +0.6 0.9 Transcriptional regulator compare
Pf1N1B4_1886 +0.6 2.5 FIG00956005: hypothetical protein compare
Pf1N1B4_1391 +0.6 2.7 Protein containing transglutaminase-like domain, putative cysteine protease compare
Pf1N1B4_3435 +0.6 1.4 ABC transporter for L-Arginine and L-Citrulline, ATPase component (from data) compare
Pf1N1B4_3956 +0.6 2.1 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) compare
Pf1N1B4_3802 +0.6 1.5 PlcB, ORFX, ORFP, ORFB, ORFA, ldh gene compare
Pf1N1B4_102 +0.6 1.5 Methyl-accepting chemotaxis protein I (serine chemoreceptor protein) compare
Pf1N1B4_5393 +0.5 1.4 hypothetical protein compare
Pf1N1B4_846 +0.5 1.2 hypothetical protein compare
Pf1N1B4_3632 +0.5 2.2 Flagellar motor rotation protein MotB compare
Pf1N1B4_2080 +0.5 2.1 hypothetical protein compare
Pf1N1B4_4358 +0.5 1.2 Acetyltransferase, GNAT family compare
Pf1N1B4_6042 +0.5 2.1 Probable transmembrane protein compare
Pf1N1B4_5453 +0.5 1.6 hypothetical protein compare
Pf1N1B4_1782 +0.5 1.4 hypothetical protein compare
Pf1N1B4_3968 +0.5 1.8 Spermidine/putrescine-binding periplasmic protein compare
Pf1N1B4_3827 +0.5 2.9 Esterase/lipase/thioesterase family protein compare
Pf1N1B4_4163 +0.5 2.3 FIG00638718: hypothetical protein compare
Pf1N1B4_307 +0.5 2.4 TesB-like acyl-CoA thioesterase 1 compare
Pf1N1B4_1774 +0.5 3.5 Ribosomal protein S6 glutaminyl transferase compare
Pf1N1B4_4181 +0.5 1.1 FIG00957123: hypothetical protein compare
Pf1N1B4_4403 +0.5 1.1 NADH dehydrogenase (EC 1.6.99.3) compare
Pf1N1B4_4590 +0.5 1.4 Oligopeptide transport system permease protein OppB (TC 3.A.1.5.1) compare
Pf1N1B4_4777 +0.5 1.5 Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) compare
Pf1N1B4_2695 +0.5 1.2 Rare lipoprotein A precursor compare
Pf1N1B4_3200 +0.5 1.9 Outer membrane lipoprotein compare
Pf1N1B4_885 +0.5 1.9 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf1N1B4_3421 +0.5 2.8 Integral membrane protein compare
Pf1N1B4_4274 +0.5 1.9 5-keto-2-deoxygluconokinase (EC 2.7.1.92) / uncharacterized domain compare
Pf1N1B4_4999 +0.5 1.7 Sugar diacid utilization regulator SdaR compare
Pf1N1B4_4937 +0.5 2.2 Two-component hybrid sensor and regulator compare
Pf1N1B4_4963 +0.5 2.4 Tricarboxylate transport protein TctC compare
Pf1N1B4_339 +0.5 1.4 UDP-glucose 4-epimerase (EC 5.1.3.2) compare
Pf1N1B4_367 +0.5 2.3 Fumarate hydratase class II (EC 4.2.1.2) compare
Pf1N1B4_2360 +0.5 1.3 hypothetical protein compare
Pf1N1B4_4863 +0.5 2.2 Outer membrane protein OprN compare
Pf1N1B4_260 +0.5 1.4 Peptide methionine sulfoxide reductase MsrB (EC 1.8.4.12) compare
Pf1N1B4_5093 +0.5 1.6 Endo-beta-1,3-glucanase compare
Pf1N1B4_3783 +0.5 1.7 FIG00958237: hypothetical protein compare
Pf1N1B4_5476 +0.5 1.2 hypothetical protein compare
Pf1N1B4_21 +0.5 1.5 Probable hydrolase compare
Pf1N1B4_3365 +0.5 2.3 Sialic acid transporter (permease) NanT compare
Pf1N1B4_1276 +0.5 1.2 Flp pilus assembly protein RcpC/CpaB compare
Pf1N1B4_756 +0.5 1.1 hypothetical protein compare
Pf1N1B4_5619 +0.5 1.8 BarA-associated response regulator UvrY (= GacA = SirA) compare
Pf1N1B4_286 +0.5 3.9 2-dehydropantoate 2-reductase (EC 1.1.1.169) compare
Pf1N1B4_5357 +0.5 0.8 hypothetical protein compare
Pf1N1B4_5886 +0.5 1.9 Undecaprenyl-phosphate galactosephosphotransferase (EC 2.7.8.6) compare
Pf1N1B4_1514 +0.5 2.1 FIG022199: FAD-binding protein compare
Pf1N1B4_1792 +0.5 1.5 Taurine transport ATP-binding protein TauB compare
Pf1N1B4_4661 +0.5 1.2 Cell division inhibitor SULA compare
Pf1N1B4_5293 +0.5 1.6 hypothetical protein compare
Pf1N1B4_2026 +0.5 1.7 Transcriptional regulator compare
Pf1N1B4_3981 +0.5 1.3 Predicted carboxypeptidase compare
Pf1N1B4_1914 +0.5 2.5 Ribosomal RNA small subunit methyltransferase B (EC 2.1.1.-) compare
Pf1N1B4_3794 +0.5 1.5 hypothetical protein compare
Pf1N1B4_3211 +0.5 1.9 Putative signal peptide protein compare
Pf1N1B4_683 +0.5 1.8 Fumarate hydratase class I, aerobic (EC 4.2.1.2) compare
Pf1N1B4_3600 +0.5 1.9 Flagellar sensor histidine kinase FleS compare
Pf1N1B4_4892 +0.5 1.7 Transcriptional regulator, AraC family compare
Pf1N1B4_3787 +0.5 1.6 FIG00960829: hypothetical protein compare
Pf1N1B4_1114 +0.5 1.7 ABC transporter, ATP-binding protein compare
Pf1N1B4_5129 +0.5 2.5 D-galacturonate transporter ExuT (from data) compare
Pf1N1B4_1511 +0.5 0.9 FIG027190: Putative transmembrane protein compare
Pf1N1B4_4819 +0.5 2.3 Multidrug resistance protein B compare
Pf1N1B4_5279 +0.5 1.3 hypothetical protein compare
Pf1N1B4_201 +0.5 1.2 ABC transporter in pyoverdin gene cluster, ATP-binding component compare
Pf1N1B4_115 +0.5 1.2 Membrane protein mosC compare
Pf1N1B4_2943 +0.5 1.5 Tryptophan synthase beta chain like (EC 4.2.1.20) compare
Pf1N1B4_1600 +0.5 2.5 FIG00955680: hypothetical protein compare
Pf1N1B4_1310 +0.5 1.7 Ribosomal protein L11 methyltransferase (EC 2.1.1.-) compare
Pf1N1B4_4669 +0.5 1.2 Heavy metal RND efflux outer membrane protein, CzcC family compare
Pf1N1B4_3514 +0.5 3.9 Sensor histidine kinase/response regulator compare
Pf1N1B4_1695 +0.5 1.0 Cystine ABC transporter, ATP-binding protein compare
Pf1N1B4_4879 +0.5 1.6 Chromosome segregation ATPases compare
Pf1N1B4_5746 +0.5 1.7 FIG139552: Putative protease compare
Pf1N1B4_758 +0.5 1.2 Bacterioferritin compare
Pf1N1B4_4458 +0.5 1.4 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) compare
Pf1N1B4_521 +0.5 2.1 ABC transporter, transmembrane region:ABC transporter:Peptidase C39, bacteriocin processing compare
Pf1N1B4_5843 +0.5 1.4 phospholipase/carboxylesterase family protein compare
Pf1N1B4_5797 +0.5 0.9 1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase (EC 1.3.1.25) compare
Pf1N1B4_4485 +0.5 1.1 membrane protein, putative compare
Pf1N1B4_4542 +0.5 1.7 IcmF-related protein compare
Pf1N1B4_4118 +0.5 1.2 Cyn operon transcriptional activator compare
Pf1N1B4_2400 +0.5 1.2 FIG00955006: hypothetical protein compare
Pf1N1B4_2287 +0.5 2.6 Protein of unknown function DUF81 compare
Pf1N1B4_5107 +0.5 1.2 Putative collagenase compare
Pf1N1B4_2085 +0.5 1.3 Uncharacterized protein similar to VCA0109 compare
Pf1N1B4_4256 +0.4 1.4 Probable transmembrane protein compare
Pf1N1B4_5029 +0.4 1.4 Molybdenum ABC transporter, periplasmic molybdenum-binding protein ModA (TC 3.A.1.8.1) compare
Pf1N1B4_5286 +0.4 1.9 hypothetical protein compare
Pf1N1B4_2635 +0.4 1.2 hypothetical protein compare
Pf1N1B4_1338 +0.4 1.8 Uncharacterized iron-regulated membrane protein; Iron-uptake factor PiuB compare
Pf1N1B4_2640 +0.4 1.7 FIG003461: hypothetical protein compare
Pf1N1B4_5777 +0.4 1.2 Nitrous oxide reductase maturation protein, outer-membrane lipoprotein NosL compare
Pf1N1B4_2382 +0.4 3.4 ATP-dependent RNA helicase RhlE compare
Pf1N1B4_2476 +0.4 2.7 Predicted signal-transduction protein containing cAMP-binding and CBS domains compare
Pf1N1B4_5367 +0.4 1.7 hypothetical protein compare


Specific Phenotypes

For 6 genes in this experiment

For carbon source Sodium D-Lactate in Pseudomonas fluorescens FW300-N1B4

For carbon source Sodium D-Lactate across organisms