Experiment set1IT016 for Sinorhizobium meliloti 1021

Compare to:

Sodium pyruvate carbon source

200 most important genes:

  gene name fitness t score description  
SMc02838 -9.1 -6.3 phosphoglyceromutase compare
SMc02899 -8.5 -8.2 prephenate dehydratase compare
SMc01494 -8.4 -10.0 phosphoserine phosphatase compare
SMc02245 -8.4 -5.8 dihydroorotate dehydrogenase 2 compare
SMc00235 -8.3 -5.7 anthranilate phosphoribosyltransferase compare
SMc03797 -8.3 -8.1 homoserine O-succinyltransferase compare
SMc00236 -8.2 -5.7 Indole-3-glycerol phosphate synthase compare
SMc02766 -8.2 -13.8 tryptophan synthase subunit beta compare
SMc00917 -8.1 -5.6 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
SMc04405 -8.1 -7.9 3-isopropylmalate dehydrogenase compare
SMc02767 -8.0 -9.6 N-(5'-phosphoribosyl)anthranilate isomerase compare
SMc02569 -8.0 -5.5 imidazole glycerol phosphate synthase subunit HisF compare
SMc01726 -8.0 -7.8 acetylglutamate kinase compare
SMc01801 -7.9 -5.0 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) compare
SMc01843 -7.9 -10.9 5,10-methylenetetrahydrofolate reductase compare
SMc01028 -7.9 -7.7 phosphopyruvate hydratase compare
SMc00918 -7.9 -5.4 ATP phosphoribosyltransferase regulatory subunit compare
SMc00993 -7.8 -7.6 phosphoribosylamine--glycine ligase compare
SMc04045 -7.7 -5.3 dihydroxy-acid dehydratase compare
SMc04002 -7.7 -9.1 phosphoribosylaminoimidazole carboxylase ATPase subunit compare
SMc03823 -7.6 -12.8 isopropylmalate isomerase large subunit compare
SMc01431 -7.6 -7.4 acetolactate synthase 3 catalytic subunit compare
SMc00488 -7.5 -17.6 phosphoribosylformylglycinamidine synthase II compare
SMc02717 -7.5 -10.2 2-isopropylmalate synthase compare
SMc00640 -7.4 -8.8 phosphoserine aminotransferase compare
SMc02137 -7.4 -5.1 ornithine carbamoyltransferase compare
SMc02725 -7.2 -12.1 anthranilate synthase compare
SMc00963 -7.2 -7.0 hypothetical protein compare
SMc00711 -7.1 -6.9 cyclohexadienyl dehydrogenase compare
SMc01054 -7.0 -6.8 required for sulfate utilization, putative electron source for sulfite reductase CysI (from data) compare
SMc04028 -6.9 -16.2 glutamate synthase compare
SMc03895 -6.9 -17.3 pyruvate carboxylase compare
SMc00494 -6.8 -2.5 phosphoribosylformylglycinamidine synthase subunit PurS compare
SMa1635 -6.8 -2.5 hypothetical protein compare
SMc02123 -6.6 -4.2 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
SMc03776 -6.6 -4.6 gamma-glutamyl kinase compare
SMc04026 -6.6 -8.8 glutamate synthase compare
SMc02217 -6.6 -7.8 O-succinylhomoserine sulfhydrylase compare
SMc02765 -6.6 -12.4 tryptophan synthase subunit alpha compare
SMc00614 -6.6 -9.0 phosphoribosylglycinamide formyltransferase compare
SMc03112 -6.5 -17.0 B12-dependent methionine synthase compare
SMc00131 -6.5 -17.8 transcriptional regulator compare
SMc03777 -6.4 -8.8 gamma-glutamyl phosphate reductase compare
SMc00554 -6.4 -8.8 amidophosphoribosyltransferase compare
SMc01360 -6.4 -4.4 aspartate carbamoyltransferase catalytic subunit compare
SMc02562 -6.3 -9.7 phosphoenolpyruvate carboxykinase compare
SMc00293 -6.3 -12.2 homoserine dehydrogenase compare
SMc02572 -6.3 -4.3 imidazole glycerol phosphate synthase subunit HisH compare
SMc03826 -6.3 -4.3 argininosuccinate synthase compare
SMc00090 -6.0 -11.3 sulfate adenylyltransferase compare
SMc00495 -6.0 -5.6 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
SMc02165 -6.0 -10.0 orotate phosphoribosyltransferase compare
SMc03069 -6.0 -4.6 6-phosphogluconolactonase compare
SMc00493 -6.0 -9.1 phosphoribosylformylglycinamidine synthase I compare
SMc04088 -5.9 -7.9 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase compare
SMc01004 -5.9 -8.6 phosphoribosyl-AMP cyclohydrolase compare
SMc00815 -5.7 -3.6 inosine 5'-monophosphate dehydrogenase compare
SMc00412 -5.7 -6.8 orotidine 5'-phosphate decarboxylase compare
SMc03229 -5.7 -3.6 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase compare
SMc00092 -5.5 -15.5 phosphoadenosine phosphosulfate reductase compare
SMc03979 -5.5 -3.8 glyceraldehyde-3-phosphate dehydrogenase compare
SMc02124 -5.4 -15.7 nitrite reductase compare
SMc01880 -5.3 -3.7 pantoate--beta-alanine ligase compare
SMc02570 -5.3 -5.3 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
SMc03763 -5.1 -3.5 cytosine-specific methyltransferase compare
SMc00615 -5.1 -6.8 phosphoribosylaminoimidazole synthetase compare
SMc03978 -5.1 -3.5 transketolase compare
SM_b21176 -5.1 -6.5 phosphate uptake ABC transporter substrate-binding protein precursor compare
SMc01361 -5.0 -6.3 dihydroorotase compare
SMc02755 -5.0 -9.1 S-adenosyl-L-homocysteine hydrolase compare
SMc01215 -5.0 -3.5 carbamoyl phosphate synthase large subunit compare
SMc02166 -5.0 -11.4 dihydroorotase compare
SM_b21175 -4.9 -5.7 phosphate uptake ABC transporter permease compare
SMc01569 -4.9 -2.4 carbamoyl phosphate synthase small subunit compare
SMc03981 -4.9 -4.0 phosphoglycerate kinase compare
SMc02975 -4.9 -11.5 phosphoenolpyruvate carboxykinase regulator transcription regulator protein compare
SMc02307 -4.7 -10.8 histidinol dehydrogenase compare
SM_b21174 -4.7 -6.6 phosphate uptake ABC transporter permease compare
SMc04001 -4.6 -1.7 phosphoribosylaminoimidazole carboxylase catalytic subunit protein compare
SMc01770 -4.6 -2.0 serine hydroxymethyltransferase compare
SMc00641 -4.5 -6.9 D-3-phosphoglycerate dehydrogenase compare
SMc00017 -4.4 -2.2 homoserine kinase compare
SMc00091 -4.4 -12.2 sulfate adenylyltransferase compare
SMc02246 -4.4 -1.6 hypothetical protein compare
SM_b21177 -4.3 -9.1 phosphate uptake ABC transporter ATP-binding protein compare
SMc02138 -4.3 -5.9 acetylornithine transaminase compare
SMc03795 -4.3 -2.2 isopropylmalate isomerase small subunit compare
SMc00876 -4.3 -9.5 ATP-binding MRP protein compare
SMc02574 -4.2 -5.6 imidazoleglycerol-phosphate dehydratase compare
SMc01881 -3.9 -3.2 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
SMc01053 -3.8 -5.2 siroheme synthase compare
SMc02425 -3.8 -6.2 transcriptional regulator compare
SMc00294 -3.6 -10.8 aminotransferase compare
SMc02707 -3.5 -7.0 hypothetical protein compare
SMc00982 -3.1 -9.3 dioxygenase compare
SMc04346 -3.0 -3.4 ketol-acid reductoisomerase compare
SMc02172 -3.0 -11.6 transcriptional regulator compare
SMc02724 -2.5 -4.3 hypothetical protein compare
SMc02227 -2.4 -8.7 fatty oxidation complex enoyl-COA hydratase/3-hydroxyacyl-COA dehydrogenase/3-hydroxybutyryl-COA epimerase compare
SMc02249 -2.4 -16.9 sensory transduction histidine kinase transmembrane protein conserved
SMc00296 -2.4 -11.2 POLY3-hydroxybutyrate polymerase compare
SMc02055 -2.3 -2.9 phytoene synthase compare
SMc01441 -2.2 -8.4 membrane bound protease compare
SMc01440 -2.2 -6.7 hydrolase serine protease transmembrane protein compare
SMc03974 -2.1 -5.2 hypothetical protein compare
SMc02983 -2.1 -6.5 ornithine, DAP, or arginine decarboxylase compare
SMc02248 -2.1 -3.2 transcriptional regulator compare
SMc02115 -1.8 -1.2 hypothetical protein compare
SMc02058 -1.7 -2.2 YAJC protein compare
SMc02385 -1.7 -3.0 hypothetical protein compare
SMc00334 -1.6 -1.8 cytidylate kinase compare
SMc00302 -1.6 -3.8 hypothetical protein compare
SMc01183 -1.5 -2.1 LexA repressor compare
SMc02753 -1.5 -1.9 PTS system transporter subunit IIA compare
SMc00414 -1.5 -9.2 hypothetical protein compare
SMc01501 -1.5 -1.8 mannitol 2-dehydrogenase compare
SMc01206 -1.4 -2.3 queuine tRNA-ribosyltransferase compare
SMc00356 -1.4 -6.0 lysyl-tRNA synthetase compare
SMa0789 -1.4 -4.4 GntR family transcriptional regulator compare
SMc04246 -1.4 -2.2 transmembrane signal peptide protein compare
SMc00450 -1.4 -1.8 protoheme IX farnesyltransferase compare
SMc01568 -1.3 -1.9 hypothetical protein compare
SMc01578 -1.3 -9.2 aspartate aminotransferase compare
SMc02228 -1.3 -6.0 acetyl-CoA acetyltransferase compare
SMc01124 -1.3 -6.0 PII uridylyl-transferase compare
SMc00838 -1.3 -5.4 hypothetical protein compare
SMc00987 -1.3 -2.2 hypothetical protein compare
SMc01845 -1.3 -1.7 transglycosylase transmembrane protein compare
SM_b20823 -1.3 -7.3 cell surface saccharide synthesis protein compare
SMc02112 -1.2 -5.4 hypothetical protein compare
SMc02229 -1.2 -8.4 acyl-CoA dehydrogenase compare
SMc02362 -1.2 -3.6 cytochrome c-type biogenesis protein CcmE compare
SMc00709 -1.2 -4.5 hypothetical protein compare
SMc02521 -1.2 -2.7 glycerol-3-phosphate regulon repressor transcription regulator protein compare
SMc01430 -1.2 -4.5 acetolactate synthase 3 regulatory subunit compare
SMc00981 -1.2 -3.9 ferredoxin protein compare
SMc01495 -1.2 -3.5 transcriptional regulator compare
SMc04000 -1.2 -0.9 hypothetical protein compare
SMc00191 -1.2 -1.7 hypothetical protein compare
SMa2020 -1.1 -4.3 Transcriptional regulator compare
SMc03878 -1.1 -2.9 acetoacetyl-CoA reductase compare
SMc00821 -1.1 -1.5 hypothetical protein compare
SMc02683 -1.1 -2.2 hypothetical protein compare
SMc01768 -1.1 -3.3 transcriptional regulator compare
SMc02582 -1.1 -3.7 hypothetical protein compare
SMc03774 -1.1 -3.3 hypothetical protein compare
SMc03949 -1.1 -2.3 nitrogen regulatory protein compare
SMc00914 -1.1 -4.9 oxidoreductase compare
SMc01364 -1.1 -1.1 DNA topoisomerase I compare
SMc02850 -1.1 -3.9 DNA polymerase I compare
SMc02812 -1.1 -3.4 hypothetical protein compare
SMc00295 -1.0 -0.7 hypothetical protein compare
SMc04093 -1.0 -8.1 acetyl-CoA synthetase compare
SMc00726 -1.0 -0.9 thiol:disulfide interchange redox-active center transmembrane protein compare
SMc02164 -1.0 -2.5 fructokinase compare
SM_b20834 -1.0 -7.1 surface saccharide synthesis protein compare
SMc01852 -1.0 -7.4 pyrophosphate--fructose-6-phosphate 1-phosphotransferase compare
SM_b20258 -1.0 -3.4 transcriptional regulator compare
SMc02659 -1.0 -3.8 GTP pyrophosphokinase (ATP:GTP 3'-pyrophosphotransferase) protein compare
SMc04260 -1.0 -5.3 transcriptional regulator compare
SMc04251 -1.0 -7.3 dctP-like component of a pyruvate transporter (from data) compare
SM_b20948 -1.0 -1.7 glucosyltransferase compare
SMc02640 -1.0 -3.6 UDP-glucuronic acid epimerase compare
SMc01119 -1.0 -1.2 hypothetical protein compare
SMc02309 -1.0 -3.5 arsenate reductase compare
SMc04407 -1.0 -7.3 transport transmembrane protein compare
SM_b20953 -0.9 -1.1 hypothetical protein compare
SMc02384 -0.9 -5.9 glycosyltransferase transmembrane protein compare
SM_b20148 -0.9 -3.3 transcriptional regulator compare
SMa1201 -0.9 -2.3 hypothetical protein compare
SMc00762 -0.9 -5.9 glutamine synthetase compare
SMc02084 -0.9 -1.1 biopolymer transport transmembrane protein compare
SMc00761 -0.9 -5.7 oxidoreductase compare
SMc02904 -0.9 -1.5 hypothetical protein compare
SMc02909 -0.9 -1.3 transglycosylase transmembrane protein compare
SMc00067 -0.9 -4.4 outer-membranne lipoprotein compare
SMc04330 -0.9 -1.6 trimethylamine methyltransferase compare
SMc04327 -0.9 -1.1 hypothetical protein compare
SMc02308 -0.9 -2.7 hypothetical protein compare
SMc03258 -0.9 -4.1 transcriptional regulator compare
SMc02677 -0.9 -3.7 pyrroline-5-carboxylate reductase compare
SMc00511 -0.9 -3.1 D-ribulose-5-phosphate 3-epimerase compare
SMc00010 -0.8 -1.7 cytochrome C oxidase polypeptide I transmembrane protein compare
SMc04248 -0.8 -5.2 hypothetical protein compare
SMc03980 -0.8 -3.0 hypothetical protein compare
SMc00013 -0.8 -1.7 cytochrome C oxidase subunit III transmembrane protein compare
SMc03993 -0.8 -4.4 hypothetical protein compare
SMa1095 -0.8 -0.8 hypothetical protein compare
SMc02641 -0.8 -3.3 UDP-glucose 6-dehydrogenase compare
SM_b20413 -0.8 -1.0 hypothetical protein compare
SMc02460 -0.8 -4.6 hypothetical protein compare
SMc04249 -0.8 -5.4 hypothetical protein compare
SM_b20055 -0.8 -1.5 transcriptional regulator compare
SMc02271 -0.8 -3.5 ribitol type dehydrogenase compare
SMc04454 -0.8 -3.3 ABC transporter ATP-binding protein compare
SMc01800 -0.8 -1.0 cytochrome C oxidase assembly transmembrane protein compare
SM_b20708 -0.8 -3.8 methylated-DNA--protein-cysteine methyltransferase compare
SMc01769 -0.8 -6.5 hypothetical protein compare
SMc00710 -0.8 -3.2 histidinol-phosphate aminotransferase compare
SM_b20909 -0.8 -2.0 hypothetical protein compare


Specific Phenotypes

For 2 genes in this experiment

For carbon source Sodium pyruvate in Sinorhizobium meliloti 1021

For carbon source Sodium pyruvate across organisms