Experiment set1IT015 for Sinorhizobium meliloti 1021

Compare to:

Sodium D,L-Lactate carbon source

200 most important genes:

  gene name fitness t score description  
SMc02766 -9.3 -6.4 tryptophan synthase subunit beta compare
SMc02899 -8.9 -6.2 prephenate dehydratase compare
SMc02767 -8.9 -6.1 N-(5'-phosphoribosyl)anthranilate isomerase compare
SMc01726 -8.9 -6.1 acetylglutamate kinase compare
SMc03797 -8.7 -6.0 homoserine O-succinyltransferase compare
SMc04405 -8.5 -5.9 3-isopropylmalate dehydrogenase compare
SMc02245 -8.4 -5.8 dihydroorotate dehydrogenase 2 compare
SMc00235 -8.2 -5.7 anthranilate phosphoribosyltransferase compare
SMc00236 -8.1 -5.6 Indole-3-glycerol phosphate synthase compare
SMc00917 -8.1 -5.6 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
SMc00640 -8.1 -5.6 phosphoserine aminotransferase compare
SMc00963 -8.1 -5.6 hypothetical protein compare
SMc04002 -8.1 -7.9 phosphoribosylaminoimidazole carboxylase ATPase subunit compare
SMc02725 -8.0 -7.8 anthranilate synthase compare
SMc03823 -7.9 -12.1 isopropylmalate isomerase large subunit compare
SMc01801 -7.8 -5.1 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) compare
SMc00918 -7.4 -7.3 ATP phosphoribosyltransferase regulatory subunit compare
SMc04045 -7.4 -7.2 dihydroxy-acid dehydratase compare
SMc01431 -7.4 -11.3 acetolactate synthase 3 catalytic subunit compare
SMc01843 -7.0 -13.4 5,10-methylenetetrahydrofolate reductase compare
SMc04028 -6.9 -16.2 glutamate synthase compare
SMc02562 -6.9 -8.3 phosphoenolpyruvate carboxykinase compare
SMc02717 -6.9 -11.5 2-isopropylmalate synthase compare
SMc03895 -6.9 -17.8 pyruvate carboxylase compare
SMc02217 -6.9 -6.7 O-succinylhomoserine sulfhydrylase compare
SMc00494 -6.8 -2.6 phosphoribosylformylglycinamidine synthase subunit PurS compare
SMc00412 -6.7 -4.6 orotidine 5'-phosphate decarboxylase compare
SMc02569 -6.7 -6.5 imidazole glycerol phosphate synthase subunit HisF compare
SMa1635 -6.7 -2.5 hypothetical protein compare
SMc01494 -6.6 -8.9 phosphoserine phosphatase compare
SMc03981 -6.6 -6.7 phosphoglycerate kinase compare
SMc01028 -6.6 -14.0 phosphopyruvate hydratase compare
SMc02137 -6.5 -6.3 ornithine carbamoyltransferase compare
SMc02123 -6.5 -4.2 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
SMc02765 -6.5 -11.9 tryptophan synthase subunit alpha compare
SMc03112 -6.5 -18.4 B12-dependent methionine synthase compare
SMc00495 -6.5 -5.3 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
SMc00554 -6.4 -7.6 amidophosphoribosyltransferase compare
SMc01004 -6.4 -9.3 phosphoribosyl-AMP cyclohydrolase compare
SMc00993 -6.3 -11.4 phosphoribosylamine--glycine ligase compare
SMc02572 -6.3 -4.3 imidazole glycerol phosphate synthase subunit HisH compare
SMc01360 -6.3 -4.3 aspartate carbamoyltransferase catalytic subunit compare
SMc00614 -6.1 -9.4 phosphoribosylglycinamide formyltransferase compare
SMc00615 -6.1 -7.5 phosphoribosylaminoimidazole synthetase compare
SMc02838 -6.0 -7.8 phosphoglyceromutase compare
SMc02124 -5.9 -17.3 nitrite reductase compare
SMc01881 -5.9 -5.7 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
SMc00711 -5.7 -6.5 cyclohexadienyl dehydrogenase compare
SMc02165 -5.7 -10.3 orotate phosphoribosyltransferase compare
SMc01361 -5.6 -7.7 dihydroorotase compare
SMc00092 -5.6 -14.5 phosphoadenosine phosphosulfate reductase compare
SMc00090 -5.6 -13.0 sulfate adenylyltransferase compare
SMc00488 -5.6 -16.6 phosphoribosylformylglycinamidine synthase II compare
SMc04088 -5.6 -8.2 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase compare
SMc01054 -5.6 -4.2 required for sulfate utilization, putative electron source for sulfite reductase CysI (from data) compare
SMc03979 -5.5 -3.8 glyceraldehyde-3-phosphate dehydrogenase compare
SMc00293 -5.5 -17.7 homoserine dehydrogenase compare
SMc04026 -5.4 -8.9 glutamate synthase compare
SMc01880 -5.3 -3.7 pantoate--beta-alanine ligase compare
SMc02166 -5.2 -10.4 dihydroorotase compare
SMc00493 -5.2 -5.8 phosphoribosylformylglycinamidine synthase I compare
SMc00131 -5.2 -16.6 transcriptional regulator compare
SMc02570 -5.1 -4.9 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
SMc03826 -5.1 -4.9 argininosuccinate synthase compare
SMc01215 -4.9 -3.4 carbamoyl phosphate synthase large subunit compare
SMc01569 -4.9 -2.5 carbamoyl phosphate synthase small subunit compare
SMc03763 -4.8 -4.7 cytosine-specific methyltransferase compare
SM_b21174 -4.7 -7.6 phosphate uptake ABC transporter permease compare
SMc00641 -4.7 -7.9 D-3-phosphoglycerate dehydrogenase compare
SMc02724 -4.7 -4.6 hypothetical protein compare
SMc04001 -4.6 -1.7 phosphoribosylaminoimidazole carboxylase catalytic subunit protein compare
SMc00091 -4.6 -13.9 sulfate adenylyltransferase compare
SMc02755 -4.6 -9.7 S-adenosyl-L-homocysteine hydrolase compare
SMc03978 -4.6 -4.4 transketolase compare
SMc01770 -4.5 -2.0 serine hydroxymethyltransferase compare
SMc00017 -4.4 -2.3 homoserine kinase compare
SMc02246 -4.4 -1.6 hypothetical protein compare
SMc03795 -4.4 -2.3 isopropylmalate isomerase small subunit compare
SMc00815 -4.3 -2.9 inosine 5'-monophosphate dehydrogenase compare
SMc03229 -4.1 -3.0 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase compare
SMc01053 -4.0 -4.9 siroheme synthase compare
SMc02975 -4.0 -9.5 phosphoenolpyruvate carboxykinase regulator transcription regulator protein compare
SM_b21175 -3.7 -6.7 phosphate uptake ABC transporter permease compare
SMc02307 -3.6 -10.3 histidinol dehydrogenase compare
SMc03070 -3.6 -9.3 glucose-6-phosphate 1-dehydrogenase compare
SMc04346 -3.5 -5.0 ketol-acid reductoisomerase compare
SM_b21177 -3.5 -8.2 phosphate uptake ABC transporter ATP-binding protein compare
SMc03069 -3.4 -4.1 6-phosphogluconolactonase compare
SMc00876 -3.3 -7.3 ATP-binding MRP protein compare
SMc02138 -3.2 -3.3 acetylornithine transaminase compare
SM_b21176 -3.2 -5.6 phosphate uptake ABC transporter substrate-binding protein precursor compare
SMc00832 -2.8 -15.3 D-lactate dehydrogenase, FAD-linked subunit GlcD (EC 1.1.99.6) (from data) conserved
SMc00926 -2.7 -14.1 D-lactate dehydrogenase, iron-sulfur subunit GlcF (EC 1.1.99.6) (from data) conserved
SMc01852 -2.5 -11.8 pyrophosphate--fructose-6-phosphate 1-phosphotransferase compare
SMc00012 -2.5 -2.4 cytochrome C oxidase assembly protein compare
SMc00294 -2.5 -10.9 aminotransferase compare
SMc03974 -2.4 -6.8 hypothetical protein compare
SMc00833 -2.4 -11.8 D-lactate dehydrogenase, FAD binding subunit GlcE (EC 1.1.99.6) (from data) conserved
SMc01592 -2.2 -6.6 transcriptional regulator compare
SMc00450 -2.2 -3.9 protoheme IX farnesyltransferase compare
SMc00013 -2.1 -3.3 cytochrome C oxidase subunit III transmembrane protein compare
SMc00025 -2.1 -6.2 pyruvate phosphate dikinase compare
SMc02558 -1.9 -6.0 hypothetical protein compare
SMc01842 -1.9 -2.0 methyltransferase transcription regulator protein compare
SMc02363 -1.9 -3.5 cytochrome C-type biogenesis transmembrane protein compare
SMc02308 -1.9 -3.2 hypothetical protein compare
SMc00296 -1.8 -10.7 POLY3-hydroxybutyrate polymerase compare
SMc00514 -1.6 -4.2 monooxygenase compare
SMc02983 -1.6 -7.1 ornithine, DAP, or arginine decarboxylase compare
SMc01363 -1.5 -2.0 hypothetical protein compare
SMc00010 -1.5 -2.1 cytochrome C oxidase polypeptide I transmembrane protein compare
SMc00295 -1.5 -1.5 hypothetical protein compare
SMc03878 -1.5 -3.2 acetoacetyl-CoA reductase compare
SMc00189 -1.5 -5.5 cytochrome C1 protein compare
SMc02141 -1.4 -4.3 phosphate transporter PhoU compare
SMc00188 -1.4 -7.5 cytochrome B transmembrane protein compare
SMc02897 -1.4 -4.0 cytochrome C transmembrane protein compare
SMc00187 -1.4 -1.7 ubiquinol-cytochrome C reductase iron-sulfur subunit protein compare
SMc02362 -1.4 -3.0 cytochrome c-type biogenesis protein CcmE compare
SMa1101 -1.3 -1.0 hypothetical protein compare
SM_b20897 -1.3 -1.2 hypothetical protein compare
SMa0144 -1.3 -1.2 hypothetical protein compare
SMa0789 -1.3 -3.3 GntR family transcriptional regulator compare
SMc00804 -1.2 -1.9 hypothetical protein compare
SMc00414 -1.2 -8.4 hypothetical protein compare
SM_b20850 -1.2 -6.4 L-lactate dehydrogenase (cytochrome) (EC 1.1.2.3) (from data) conserved
SMc00419 -1.2 -4.0 glutathione synthetase compare
SMc00009 -1.2 -4.7 cytochrome C oxidase subunit II protein compare
SMa2020 -1.2 -3.7 Transcriptional regulator compare
SMc00241 -1.2 -2.2 transcriptional regulator compare
SMc00302 -1.2 -3.0 hypothetical protein compare
SMc04262 -1.2 -6.8 6-phosphogluconate dehydrogenase compare
SMc02112 -1.1 -3.3 hypothetical protein compare
SMc01023 -1.1 -4.1 triosephosphate isomerase compare
SMc02659 -1.1 -4.7 GTP pyrophosphokinase (ATP:GTP 3'-pyrophosphotransferase) protein compare
SMc02172 -1.1 -5.1 transcriptional regulator compare
SMc00356 -1.1 -3.5 lysyl-tRNA synthetase compare
SMc03980 -1.0 -3.6 hypothetical protein compare
SMc01505 -1.0 -0.6 hypothetical protein compare
SMc04348 -1.0 -1.0 transcriptional regulator compare
SMc02253 -0.9 -4.0 salicylate biosynthesis protein compare
SMc02102 -0.9 -2.7 hypothetical protein compare
SMa0905 -0.9 -1.3 hypothetical protein compare
SMc01364 -0.9 -1.0 DNA topoisomerase I compare
SMc03850 -0.9 -1.2 heme exporter D (cytochrome C-type biogenesis protein) transmembrane compare
SMc00405 -0.9 -4.3 hypothetical protein compare
SMc00166 -0.9 -0.9 oxidoreductase NAD protein compare
SMc03258 -0.9 -3.7 transcriptional regulator compare
SMc00085 -0.9 -2.9 cytochrome oxidase complex biogenesis factor transmembrane protein compare
SMc00709 -0.9 -3.1 hypothetical protein compare
SMc03849 -0.9 -0.9 heme exporter C (cytochrome C-type biogenesis protein) transmembrane compare
SMc00492 -0.9 -0.9 hypothetical protein compare
SMc01260 -0.8 -3.5 transcriptional regulator compare
SMc00760 -0.8 -2.6 recombinase A compare
SMc01206 -0.8 -1.4 queuine tRNA-ribosyltransferase compare
SMc02407 -0.8 -3.9 hypothetical protein compare
SMc02361 -0.8 -2.7 cytochrome C-type biogenesis transmembrane protein compare
SM_b20773 -0.8 -2.2 GntR family transcriptional regulator compare
SM_b20105 -0.8 -1.5 transcriptional regulator compare
SMc03140 -0.8 -3.3 transcriptional regulator compare
SMc00361 -0.8 -1.7 hypothetical protein compare
SMa0882 -0.8 -1.1 hypothetical protein compare
SM_b21173 -0.8 -1.4 hypothetical protein compare
SM_b20003 -0.8 -2.2 pyrroline-5-carboxylate reductase compare
SMc02227 -0.8 -3.2 fatty oxidation complex enoyl-COA hydratase/3-hydroxyacyl-COA dehydrogenase/3-hydroxybutyryl-COA epimerase compare
SMc04093 -0.8 -6.2 acetyl-CoA synthetase compare
SMa1118 -0.8 -1.0 HspC2 heat shock protein compare
SMc04000 -0.8 -0.5 hypothetical protein compare
SMc01800 -0.8 -0.9 cytochrome C oxidase assembly transmembrane protein compare
SMc00579 -0.8 -2.4 dimethyladenosine transferase compare
SM_b22005 -0.8 -1.2 hypothetical protein compare
SMc04003 -0.7 -1.6 50S ribosomal protein L36 compare
SMc01147 -0.7 -2.3 coproporphyrinogen III oxidase compare
SMc02147 -0.7 -3.6 phosphate regulon sensor histidine kinase transmembrane protein compare
SMc02574 -0.7 -1.6 imidazoleglycerol-phosphate dehydratase compare
SMc00853 -0.7 -2.6 hypothetical protein compare
SM_b21347 -0.7 -1.4 pectin degradation protein compare
SMc02510 -0.7 -0.6 ferric uptake regulation protein compare
SMc01124 -0.7 -4.2 PII uridylyl-transferase compare
SMc02115 -0.7 -0.7 hypothetical protein compare
SMc02164 -0.7 -1.2 fructokinase compare
SMc00775 -0.7 -4.9 iron(III) permease compare
SMc02144 -0.7 -2.0 phosphate ABC transporter permease compare
SMc00761 -0.7 -4.0 oxidoreductase compare
SM_b20862 -0.7 -1.7 hypothetical protein compare
SM_b20758 -0.7 -1.4 ArsR family transcriptional regulator compare
SMc02425 -0.7 -2.1 transcriptional regulator compare
SM_b20703 -0.7 -2.5 hypothetical protein compare
SM_b21454 -0.7 -1.4 hypothetical protein compare
SMc03967 -0.7 -0.6 Holliday junction resolvase compare
SMa1700 -0.7 -1.1 hypothetical protein compare
SMa0645 -0.7 -1.1 hypothetical protein compare
SMc03746 -0.7 -0.8 hypothetical protein compare
SMc02695 -0.7 -3.3 GTP-dependent nucleic acid-binding protein EngD compare
SMc01522 -0.7 -1.4 hypothetical protein compare
SMc04453 -0.7 -0.9 hypothetical protein compare
SMc02573 -0.7 -0.7 hypothetical protein compare
SM_b20294 -0.7 -1.0 transcriptional regulator NanR compare
SMc03008 -0.7 -0.9 chemotaxis protein compare
SMc02068 -0.6 -4.2 ABC transporter ATP-binding protein compare


Specific Phenotypes

For 8 genes in this experiment

For carbon source Sodium D,L-Lactate in Sinorhizobium meliloti 1021

For carbon source Sodium D,L-Lactate across organisms