Experiment set1IT014 for Pseudomonas fluorescens FW300-N2E2

Compare to:

Sodium propionate carbon source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_3842 -7.1 -4.9 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_3782 -6.9 -4.7 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_4597 -6.9 -9.4 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_4279 -6.8 -11.3 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_4826 -6.7 -7.9 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_71 -6.3 -6.2 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_4825 -6.3 -9.7 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_6062 -6.1 -9.3 2-methylcitrate synthase (EC 2.3.3.5) (from data) compare
Pf6N2E2_3630 -6.0 -8.2 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_4071 -6.0 -6.6 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_3253 -6.0 -7.1 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_2574 -5.7 -3.5 Flagellar synthesis regulator FleN compare
Pf6N2E2_4278 -5.6 -14.5 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_3783 -5.6 -5.8 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_3839 -5.5 -6.6 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_5176 -5.4 -12.7 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_5175 -5.4 -18.0 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_4596 -5.4 -12.9 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_302 -5.3 -8.1 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_64 -5.2 -3.8 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_4047 -5.1 -7.0 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_5723 -5.1 -11.9 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
Pf6N2E2_5014 -5.1 -1.6 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_5177 -5.1 -12.7 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_4579 -5.0 -3.5 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
Pf6N2E2_248 -4.9 -11.3 hypothetical protein compare
Pf6N2E2_3610 -4.8 -4.5 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_3264 -4.8 -3.5 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_77 -4.8 -6.8 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_5153 -4.7 -9.6 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) compare
Pf6N2E2_4048 -4.7 -7.8 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_6064 -4.7 -7.8 2-methylaconitate isomerase compare
Pf6N2E2_3248 -4.7 -6.7 Probable transmembrane protein compare
Pf6N2E2_3252 -4.6 -11.5 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_6060 -4.6 -5.4 Propionate catabolism operon transcriptional regulator of GntR family [predicted] conserved
Pf6N2E2_3257 -4.6 -4.5 Uncharacterized ABC transporter, auxiliary component YrbC compare
Pf6N2E2_3932 -4.5 -7.0 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_2217 -4.4 -7.4 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_2074 -4.4 -1.9 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_4277 -4.4 -10.6 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_5160 -4.3 -1.9 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_4564 -4.3 -8.0 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_288 -4.1 -3.9 Isocitrate dehydrogenase [NADP] (EC 1.1.1.42); Monomeric isocitrate dehydrogenase [NADP] (EC 1.1.1.42) compare
Pf6N2E2_2073 -4.1 -9.4 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_4204 -4.0 -2.5 rRNA small subunit 7-methylguanosine (m7G) methyltransferase GidB compare
Pf6N2E2_66 -4.0 -8.6 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_6061 -4.0 -9.6 Methylisocitrate lyase (EC 4.1.3.30) (from data) conserved
Pf6N2E2_6063 -4.0 -11.7 2-methylcitrate dehydratase FeS dependent (EC 4.2.1.79) compare
Pf6N2E2_5156 -4.0 -3.9 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_3611 -3.9 -2.5 HflC protein compare
Pf6N2E2_3908 -3.8 -10.1 Glutamate--cysteine ligase (EC 6.3.2.2) compare
Pf6N2E2_4072 -3.7 -6.7 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
Pf6N2E2_4075 -3.7 -7.9 Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1) compare
Pf6N2E2_2261 -3.7 -9.8 VacJ-like lipoprotein precursor compare
Pf6N2E2_3751 -3.7 -14.3 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_5103 -3.7 -1.5 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
Pf6N2E2_4761 -3.7 -12.0 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf6N2E2_3612 -3.7 -3.6 HflK protein compare
Pf6N2E2_3661 -3.7 -7.4 hypothetical protein compare
Pf6N2E2_1636 -3.7 -12.2 Ferrichrome-iron receptor compare
Pf6N2E2_3940 -3.7 -10.1 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_5950 -3.6 -5.9 Phosphate:acyl-ACP acyltransferase PlsX compare
Pf6N2E2_50 -3.6 -9.3 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_4599 -3.6 -4.5 Integral membrane protein YggT, involved in response to extracytoplasmic stress (osmotic shock) compare
Pf6N2E2_4763 -3.6 -12.6 Biotin synthesis protein BioC compare
Pf6N2E2_3752 -3.6 -18.3 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_5178 -3.6 -2.4 CDP-diacylglycerol--serine O-phosphatidyltransferase (EC 2.7.8.8) compare
Pf6N2E2_4638 -3.5 -5.5 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_4764 -3.3 -7.2 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_4759 -3.2 -14.4 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_5006 -3.2 -6.7 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_5242 -3.2 -3.1 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_5258 -3.2 -9.1 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_2258 -3.2 -13.4 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_3261 -3.2 -5.8 hypothetical protein compare
Pf6N2E2_5520 -3.1 -10.2 Sensory box histidine kinase compare
Pf6N2E2_5527 -3.1 -2.8 Cold shock protein CspC compare
Pf6N2E2_2218 -3.1 -5.7 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_5190 -3.1 -11.5 Carbonic anhydrase (EC 4.2.1.1) compare
Pf6N2E2_3841 -3.1 -5.5 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_3884 -3.0 -7.5 Histone acetyltransferase HPA2 and related acetyltransferases conserved
Pf6N2E2_4612 -3.0 -5.6 Glutathione synthetase (EC 6.3.2.3) compare
Pf6N2E2_5279 -3.0 -6.9 Hypothetical flavoprotein YqcA (clustered with tRNA pseudouridine synthase C) conserved
Pf6N2E2_2282 -3.0 -5.7 Predicted transcriptional regulator for fatty acid degradation FadQ, TetR family compare
Pf6N2E2_3258 -2.9 -7.2 Uncharacterized ABC transporter, periplasmic component YrbD compare
Pf6N2E2_5157 -2.8 -11.1 Two-component sensor CbrA: intrcellular carbon:nitrogen balance compare
Pf6N2E2_3260 -2.8 -7.9 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
Pf6N2E2_2465 -2.8 -7.4 Cys regulon transcriptional activator CysB compare
Pf6N2E2_2274 -2.8 -7.9 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) compare
Pf6N2E2_5257 -2.8 -7.8 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_3170 -2.7 -6.9 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_4631 -2.7 -8.5 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf6N2E2_5728 -2.7 -4.6 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_4611 -2.7 -5.5 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_3270 -2.7 -5.9 Hypothetical ATP-binding protein UPF0042, contains P-loop compare
Pf6N2E2_5406 -2.6 -3.5 FIG00958224: hypothetical protein compare
Pf6N2E2_2277 -2.6 -2.5 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_5579 -2.6 -5.4 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_4800 -2.5 -13.1 yeaH component of nitrogen-related signalling system yeaH (of yeaGH-ycgB) (from data) conserved
Pf6N2E2_4762 -2.5 -2.8 Biotin synthesis protein BioH compare
Pf6N2E2_3251 -2.5 -10.2 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_2188 -2.5 -4.6 Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family compare
Pf6N2E2_3103 -2.5 -10.4 Phosphoenolpyruvate carboxylase (EC 4.1.1.31) conserved
Pf6N2E2_63 -2.5 -3.0 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_4276 -2.5 -6.0 Phosphogluconate repressor HexR, RpiR family compare
Pf6N2E2_424 -2.4 -7.5 Decarboxylase family protein conserved
Pf6N2E2_1626 -2.4 -7.6 Putative ATP-binding component of a transport system compare
Pf6N2E2_5714 -2.3 -4.0 Flavoprotein WrbA compare
Pf6N2E2_3666 -2.3 -4.2 InaA protein compare
Pf6N2E2_2753 -2.3 -3.6 HtrA protease/chaperone protein compare
Pf6N2E2_3183 -2.3 -3.5 Believed to be involved in assembly of Fe-S clusters compare
Pf6N2E2_4120 -2.2 -10.8 Trk system potassium uptake protein TrkA compare
Pf6N2E2_4372 -2.2 -5.8 FIG00460773: hypothetical protein compare
Pf6N2E2_3984 -2.2 -8.7 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_4352 -2.1 -3.4 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf6N2E2_2514 -2.1 -3.6 regulator of length of O-antigen component of lipopolysaccharide chains compare
Pf6N2E2_5182 -2.1 -8.9 Paraquat-inducible protein A compare
Pf6N2E2_2176 -2.1 -2.8 Amidases related to nicotinamidase compare
Pf6N2E2_5181 -2.1 -10.1 Paraquat-inducible protein A compare
Pf6N2E2_3460 -2.1 -2.0 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_3505 -2.1 -2.0 Translation initiation factor SUI1-related protein compare
Pf6N2E2_634 -2.0 -9.9 NAD-specific glutamate dehydrogenase (EC 1.4.1.2), large form compare
Pf6N2E2_5183 -2.0 -12.2 Paraquat-inducible protein B compare
Pf6N2E2_3062 -2.0 -4.0 Membrane-associated zinc metalloprotease compare
Pf6N2E2_2825 -2.0 -5.0 RND efflux system, outer membrane lipoprotein CmeC compare
Pf6N2E2_5545 -2.0 -5.6 Queuosine Biosynthesis QueE Radical SAM compare
Pf6N2E2_4993 -1.9 -2.9 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) compare
Pf6N2E2_5671 -1.9 -3.4 Succinylglutamate desuccinylase (EC 3.5.1.96) compare
Pf6N2E2_3665 -1.9 -1.0 serine/threonine protein kinase compare
Pf6N2E2_4601 -1.9 -3.1 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC compare
Pf6N2E2_3770 -1.9 -3.0 ATP-dependent hsl protease ATP-binding subunit HslU compare
Pf6N2E2_4799 -1.9 -10.6 ycgB component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) conserved
Pf6N2E2_5111 -1.8 -2.7 FKBP-type peptidyl-prolyl cis-trans isomerase SlpA (EC 5.2.1.8) compare
Pf6N2E2_2823 -1.8 -4.6 Multidrug efflux RND membrane fusion protein MexC compare
Pf6N2E2_5505 -1.8 -2.4 hypothetical protein compare
Pf6N2E2_4009 -1.8 -6.0 GGDEF domain protein compare
Pf6N2E2_2634 -1.8 -8.0 Potassium uptake protein TrkH compare
Pf6N2E2_1673 -1.8 -2.4 Transcriptional regulator, TetR family compare
Pf6N2E2_4614 -1.8 -3.4 twitching motility protein PilH compare
Pf6N2E2_1625 -1.8 -3.0 Ferric reductase (1.6.99.14) compare
Pf6N2E2_5553 -1.7 -6.9 Quinolinate synthetase (EC 2.5.1.72) compare
Pf6N2E2_4074 -1.7 -9.4 Phosphate transport system permease protein PstC (TC 3.A.1.7.1) compare
Pf6N2E2_5494 -1.7 -4.5 Pyruvate kinase (EC 2.7.1.40) compare
Pf6N2E2_4159 -1.7 -3.9 Cytochrome c4 compare
Pf6N2E2_5741 -1.7 -6.8 L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81) compare
Pf6N2E2_3384 -1.7 -3.9 Predicted L-lactate dehydrogenase, hypothetical protein subunit YkgG compare
Pf6N2E2_3807 -1.7 -5.3 Histidine utilization repressor compare
Pf6N2E2_2061 -1.7 -3.6 CobW GTPase involved in cobalt insertion for B12 biosynthesis compare
Pf6N2E2_4187 -1.7 -3.9 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_2473 -1.7 -1.4 Major outer membrane lipoprotein I compare
Pf6N2E2_2886 -1.6 -10.8 Phosphogluconate repressor HexR, RpiR family compare
Pf6N2E2_2827 -1.6 -1.2 hypothetical protein compare
Pf6N2E2_4453 -1.6 -11.6 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_3533 -1.6 -4.5 Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) compare
Pf6N2E2_1743 -1.6 -2.9 Putrescine transport ATP-binding protein PotA (TC 3.A.1.11.1) compare
Pf6N2E2_4801 -1.6 -9.7 yeaG component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) conserved
Pf6N2E2_5331 -1.6 -6.2 ATPase, AFG1 family compare
Pf6N2E2_4272 -1.6 -2.9 putative membrane protein compare
Pf6N2E2_1656 -1.6 -2.5 hypothetical protein compare
Pf6N2E2_3074 -1.5 -1.5 FIG00960973: hypothetical protein compare
Pf6N2E2_3346 -1.5 -5.4 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf6N2E2_1870 -1.5 -2.2 hypothetical protein compare
Pf6N2E2_2824 -1.5 -6.7 RND efflux system, inner membrane transporter CmeB compare
Pf6N2E2_2702 -1.5 -3.7 FIG00962464: hypothetical protein compare
Pf6N2E2_5155 -1.5 -2.2 Poly(A) polymerase (EC 2.7.7.19) compare
Pf6N2E2_37 -1.5 -4.3 6-carboxytetrahydropterin synthase (EC 4.1.2.50) @ Queuosine biosynthesis QueD, PTPS-I compare
Pf6N2E2_4969 -1.5 -1.2 hypothetical protein compare
Pf6N2E2_2533 -1.5 -7.4 Rhodanese domain protein UPF0176 conserved
Pf6N2E2_3534 -1.5 -2.2 Cobalamin biosynthesis protein CobG compare
Pf6N2E2_5538 -1.5 -5.0 4-hydroxybenzoyl-CoA thioesterase family active site compare
Pf6N2E2_6140 -1.5 -1.1 Large Subunit Ribosomal RNA; lsuRNA; LSU rRNA compare
Pf6N2E2_4987 -1.4 -1.1 MaoC-like domain protein compare
Pf6N2E2_178 -1.4 -1.0 Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) compare
Pf6N2E2_2755 -1.4 -1.4 Sigma factor RpoE negative regulatory protein RseA compare
Pf6N2E2_5316 -1.4 -1.7 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_5679 -1.4 -2.4 hypothetical protein compare
Pf6N2E2_5093 -1.4 -8.8 ATP-dependent protease La (EC 3.4.21.53) Type II compare
Pf6N2E2_2010 -1.4 -1.3 hypothetical protein compare
Pf6N2E2_3454 -1.4 -2.3 hypothetical protein compare
Pf6N2E2_2693 -1.4 -1.6 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.180) compare
Pf6N2E2_1821 -1.4 -1.9 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system compare
Pf6N2E2_1124 -1.4 -1.5 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_5745 -1.4 -4.8 Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73) compare
Pf6N2E2_3037 -1.4 -7.7 RNA polymerase sigma factor RpoS compare
Pf6N2E2_601 -1.4 -3.3 GlpG protein (membrane protein of glp regulon) compare
Pf6N2E2_2062 -1.4 -2.2 FIG00955561: hypothetical protein compare
Pf6N2E2_5188 -1.4 -4.7 Ribosomal-protein-S18p-alanine acetyltransferase (EC 2.3.1.-) compare
Pf6N2E2_922 -1.3 -2.9 FIG00794167: hypothetical protein compare
Pf6N2E2_5955 -1.3 -3.5 Aminodeoxychorismate lyase (EC 4.1.3.38) compare
Pf6N2E2_5571 -1.3 -1.4 hypothetical protein compare
Pf6N2E2_2422 -1.3 -6.1 Molybdopterin biosynthesis protein MoeA compare
Pf6N2E2_3201 -1.3 -3.1 Transcriptional regulator, MerR family compare
Pf6N2E2_3283 -1.3 -4.7 Cytoplasmic axial filament protein CafA and Ribonuclease G (EC 3.1.4.-) compare
Pf6N2E2_2727 -1.3 -4.3 Ribonuclease D (EC 3.1.26.3) compare
Pf6N2E2_3876 -1.3 -4.4 Agmatine deiminase (EC 3.5.3.12) compare
Pf6N2E2_600 -1.3 -1.5 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases compare
Pf6N2E2_621 -1.3 -4.3 TPR domain protein in aerotolerance operon compare
Pf6N2E2_5733 -1.3 -3.8 NLP/P60 family protein compare
Pf6N2E2_2586 -1.3 -1.3 Hpt domain protein compare
Pf6N2E2_3096 -1.2 -1.2 Periplasmic protein TonB, links inner and outer membranes compare


Specific Phenotypes

For 25 genes in this experiment

For carbon source Sodium propionate in Pseudomonas fluorescens FW300-N2E2

For carbon source Sodium propionate across organisms