Experiment set1IT014 for Pseudomonas fluorescens FW300-N2E2

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Sodium propionate carbon source

200 most detrimental genes:

  gene name fitness t score description  
Pf6N2E2_5370 +5.3 40.8 LysR family transcriptional regulator QseA conserved
Pf6N2E2_4077 +4.5 13.7 cytosolic long-chain acyl-CoA thioester hydrolase family protein compare
Pf6N2E2_2605 +3.4 17.7 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.180) compare
Pf6N2E2_5720 +3.4 24.4 BarA sensory histidine kinase (= VarS = GacS) compare
Pf6N2E2_2022 +3.2 16.9 BarA-associated response regulator UvrY (= GacA = SirA) compare
Pf6N2E2_2606 +3.1 12.9 hypothetical protein compare
Pf6N2E2_2986 +2.9 13.7 Transcriptional regulator, LuxR family compare
Pf6N2E2_5894 +2.8 14.9 Putative threonine efflux protein compare
Pf6N2E2_5899 +2.7 11.7 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system compare
Pf6N2E2_1981 +2.6 7.6 FIG051360: Periplasmic protein TonB, links inner and outer membranes compare
Pf6N2E2_5760 +2.5 20.6 Sensory box histidine kinase/response regulator conserved
Pf6N2E2_2642 +2.4 17.6 putative patatin-like phospholipase compare
Pf6N2E2_5961 +2.2 13.8 Transcriptional regulator, TetR family conserved
Pf6N2E2_828 +2.2 6.6 Transcriptional regulator, TetR family compare
Pf6N2E2_4041 +2.1 18.9 Acetyl-CoA hydrolase (EC 3.1.2.1) conserved
Pf6N2E2_1442 +1.9 10.2 Transcriptional regulators of sugar metabolism compare
Pf6N2E2_3942 +1.9 12.9 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
Pf6N2E2_4369 +1.8 6.0 Exodeoxyribonuclease III (EC 3.1.11.2) compare
Pf6N2E2_3607 +1.8 9.9 3'-to-5' exoribonuclease RNase R compare
Pf6N2E2_2278 +1.8 14.5 Transcription-repair coupling factor compare
Pf6N2E2_5659 +1.6 14.8 Acetyl-coenzyme A synthetase (EC 6.2.1.1) compare
Pf6N2E2_289 +1.6 11.7 Isocitrate dehydrogenase [NADP] (EC 1.1.1.42) compare
Pf6N2E2_3978 +1.6 10.2 Type I secretion system, membrane fusion protein LapC compare
Pf6N2E2_5304 +1.5 10.4 ribosomal subunit interface protein, putative conserved
Pf6N2E2_5226 +1.5 3.0 FIG00955589: hypothetical protein compare
Pf6N2E2_3979 +1.5 9.9 Type I secretion system ATPase, LssB family LapB compare
Pf6N2E2_2578 +1.5 5.7 Flagellar biosynthesis protein FliR compare
Pf6N2E2_3883 +1.4 2.7 C4-dicarboxylate transport transcriptional regulatory protein compare
Pf6N2E2_2592 +1.4 8.1 Flagellar motor switch protein FliG compare
Pf6N2E2_3659 +1.4 5.4 Protein fixF compare
Pf6N2E2_3981 +1.4 10.8 T1SS secreted agglutinin RTX compare
Pf6N2E2_3885 +1.3 3.5 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
Pf6N2E2_2869 +1.3 2.1 Peptide deformylase (EC 3.5.1.88) compare
Pf6N2E2_3980 +1.3 8.0 Type I secretion system, outer membrane component LapE compare
Pf6N2E2_649 +1.3 3.3 General secretion pathway protein L compare
Pf6N2E2_2513 +1.3 3.6 UDP-glucose dehydrogenase (EC 1.1.1.22) compare
Pf6N2E2_4797 +1.3 2.5 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_2286 +1.3 4.5 FIG00953287: hypothetical protein compare
Pf6N2E2_2402 +1.3 2.5 hypothetical protein compare
Pf6N2E2_5727 +1.2 6.8 FIG00955360: hypothetical protein compare
Pf6N2E2_2593 +1.2 4.8 Flagellar M-ring protein FliF compare
Pf6N2E2_1089 +1.2 2.5 Delta 1-piperideine-2-carboxylate reductase (EC 1.5.1.21) / Delta 1-pyrroline-2-carboxylate reductase (EC 1.5.1.1) compare
Pf6N2E2_4362 +1.2 4.4 DNA-directed RNA polymerase omega subunit (EC 2.7.7.6) compare
Pf6N2E2_4624 +1.2 1.8 Phosphoribosyl-dephospho-CoA transferase (EC 2.7.7.-) compare
Pf6N2E2_5843 +1.2 3.2 hypothetical protein compare
Pf6N2E2_2510 +1.2 3.3 Lipid carrier : UDP-N-acetylgalactosaminyltransferase (EC 2.4.1.-) / Alpha-1,3-N-acetylgalactosamine transferase PglA (EC 2.4.1.-); Putative glycosyltransferase compare
Pf6N2E2_5015 +1.2 4.8 Magnesium and cobalt efflux protein CorC compare
Pf6N2E2_3455 +1.2 3.4 Integral membrane protein YfiB compare
Pf6N2E2_2594 +1.1 4.9 Flagellar hook-basal body complex protein FliE compare
Pf6N2E2_2471 +1.1 7.9 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_3268 +1.1 7.6 Ribosome hibernation protein YhbH conserved
Pf6N2E2_4509 +1.1 6.6 Gamma-glutamyl-putrescine synthetase (EC 6.3.1.11) (from data) compare
Pf6N2E2_2576 +1.1 8.1 Flagellar biosynthesis protein FlhA compare
Pf6N2E2_2788 +1.1 3.0 Transcriptional regulator, AsnC family compare
Pf6N2E2_3762 +1.1 5.8 NADP-dependent malic enzyme (EC 1.1.1.40) compare
Pf6N2E2_4556 +1.1 4.6 FIG00953078: hypothetical protein compare
Pf6N2E2_4068 +1.1 8.6 Phosphate regulon metal ion transporter containing CBS domains compare
Pf6N2E2_840 +1.1 5.6 Alcohol dehydrogenase (EC 1.1.1.1) compare
Pf6N2E2_525 +1.1 4.0 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_3351 +1.1 4.6 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
Pf6N2E2_2045 +1.0 3.7 Peptidyl-prolyl cis-trans isomerase PpiC (EC 5.2.1.8) compare
Pf6N2E2_144 +1.0 8.7 Uncharacterized protein YtfM precursor compare
Pf6N2E2_1726 +1.0 5.6 3-methylmercaptopropionyl-CoA ligase (DmdB) compare
Pf6N2E2_3763 +1.0 1.8 hypothetical protein compare
Pf6N2E2_5235 +1.0 7.7 Uracil phosphoribosyltransferase (EC 2.4.2.9) compare
Pf6N2E2_5694 +1.0 4.1 Flagellar basal-body rod protein FlgB compare
Pf6N2E2_1774 +1.0 1.5 DNA-binding response regulator, LuxR family, near polyamine transporter compare
Pf6N2E2_2675 +1.0 1.2 ATP-dependent RNA helicase SrmB compare
Pf6N2E2_724 +1.0 2.2 Nitric oxide -responding transcriptional regulator Dnr (Crp/Fnr family) compare
Pf6N2E2_737 +1.0 1.1 Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4) compare
Pf6N2E2_2579 +0.9 3.8 Flagellar biosynthesis protein FliQ compare
Pf6N2E2_4584 +0.9 2.6 Cell division transporter, ATP-binding protein FtsE (TC 3.A.5.1.1) compare
Pf6N2E2_2296 +0.9 1.6 FIG00954767: hypothetical protein compare
Pf6N2E2_5695 +0.9 4.3 Flagellar basal-body rod protein FlgC compare
Pf6N2E2_145 +0.9 4.7 putative exported protein compare
Pf6N2E2_464 +0.9 1.5 Sensory histidine kinase QseC compare
Pf6N2E2_4918 +0.9 3.0 Ribonucleotide reductase transcriptional regulator NrdR compare
Pf6N2E2_2534 +0.9 3.4 Cell division protein BolA compare
Pf6N2E2_2624 +0.9 4.6 Flagellar protein FlgJ [peptidoglycan hydrolase] (EC 3.2.1.-) compare
Pf6N2E2_2523 +0.9 5.9 Methylthioribose-1-phosphate isomerase (EC 5.3.1.23) compare
Pf6N2E2_3179 +0.9 1.7 FIG021952: putative membrane protein compare
Pf6N2E2_2589 +0.9 2.5 Flagellar protein FliJ compare
Pf6N2E2_1147 +0.9 1.6 Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) compare
Pf6N2E2_533 +0.9 3.0 Na(+) H(+) antiporter subunit G compare
Pf6N2E2_2607 +0.9 5.7 N-acetylneuraminate synthase (EC 2.5.1.56) compare
Pf6N2E2_2425 +0.9 2.2 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_700 +0.9 2.6 Heme d1 biosynthesis protein NirL compare
Pf6N2E2_1169 +0.9 2.1 TnpR protein compare
Pf6N2E2_6164 +0.9 1.3 tRNA-Val-TAC compare
Pf6N2E2_2864 +0.9 1.5 Gluconokinase (EC 2.7.1.12) compare
Pf6N2E2_4451 +0.9 4.6 FIG139438: lipoprotein B compare
Pf6N2E2_4477 +0.9 2.5 Z-ring-associated protein ZapA compare
Pf6N2E2_1405 +0.9 4.0 Nitrous oxide reductase maturation protein NosF (ATPase) compare
Pf6N2E2_1136 +0.9 1.0 Transcriptional regulator, TetR family compare
Pf6N2E2_1312 +0.9 1.9 4-hydroxyphenylacetate symporter, major facilitator superfamily (MFS) compare
Pf6N2E2_3930 +0.9 6.0 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain compare
Pf6N2E2_425 +0.9 2.3 FIG00957304: hypothetical protein compare
Pf6N2E2_719 +0.9 2.2 Molybdenum cofactor biosynthesis protein MoaB compare
Pf6N2E2_6100 +0.8 1.4 tRNA-Val-TAC compare
Pf6N2E2_2580 +0.8 2.2 Flagellar biosynthesis protein FliP compare
Pf6N2E2_6047 +0.8 1.4 hypothetical protein compare
Pf6N2E2_5697 +0.8 6.1 Flagellar hook protein FlgE compare
Pf6N2E2_2582 +0.8 2.6 Flagellar motor switch protein FliN compare
Pf6N2E2_1677 +0.8 3.0 Chalcone synthase (EC 2.3.1.74) compare
Pf6N2E2_4752 +0.8 6.4 Malate synthase G (EC 2.3.3.9) compare
Pf6N2E2_1978 +0.8 2.6 DNA topoisomerase III (EC 5.99.1.2) in PFGI-1-like cluster compare
Pf6N2E2_4478 +0.8 4.6 FIG019278: hypothetical protein compare
Pf6N2E2_2438 +0.8 1.0 hypothetical protein compare
Pf6N2E2_4087 +0.8 4.6 L-asparaginase (EC 3.5.1.1) (from data) compare
Pf6N2E2_2323 +0.8 2.2 Fumarate and nitrate reduction regulatory protein compare
Pf6N2E2_5510 +0.8 1.6 FIG00955324: hypothetical protein compare
Pf6N2E2_2469 +0.8 3.5 hypothetical protein compare
Pf6N2E2_3271 +0.8 1.6 Phosphocarrier protein, nitrogen regulation associated compare
Pf6N2E2_4630 +0.8 2.4 Ribosomal RNA small subunit methyltransferase E (EC 2.1.1.-) compare
Pf6N2E2_1110 +0.8 2.3 FIG00964414: hypothetical protein compare
Pf6N2E2_3667 +0.8 1.0 Heptose kinase WapQ, eukaryotic type compare
Pf6N2E2_5328 +0.8 3.5 FIG00958649: hypothetical protein compare
Pf6N2E2_1195 +0.8 2.0 hypothetical protein compare
Pf6N2E2_3206 +0.8 1.5 hypothetical protein compare
Pf6N2E2_4139 +0.8 5.2 Integral membrane protein TerC compare
Pf6N2E2_605 +0.8 1.8 FIG002465: BNR repeat protein compare
Pf6N2E2_5874 +0.8 6.4 TonB-dependent receptor; Outer membrane receptor for ferrienterochelin and colicins compare
Pf6N2E2_2577 +0.8 3.9 Flagellar biosynthesis protein FlhB compare
Pf6N2E2_2822 +0.8 4.2 Transcription repressor of multidrug efflux pump acrAB operon, TetR (AcrR) family compare
Pf6N2E2_2267 +0.8 3.2 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) compare
Pf6N2E2_2625 +0.8 2.4 Flagellar P-ring protein FlgI compare
Pf6N2E2_2519 +0.7 0.9 Biosynthetic Aromatic amino acid aminotransferase beta (EC 2.6.1.57) compare
Pf6N2E2_2583 +0.7 3.2 Flagellar motor switch protein FliM compare
Pf6N2E2_2129 +0.7 1.8 Predicted dye-decolorizing peroxidase (DyP), YfeX-like subgroup compare
Pf6N2E2_4479 +0.7 1.6 FIG001590: Putative conserved exported protein precursor compare
Pf6N2E2_4555 +0.7 4.1 Lysophospholipase (EC 3.1.1.5) compare
Pf6N2E2_3625 +0.7 4.4 Flagellar motor rotation protein MotA compare
Pf6N2E2_5691 +0.7 3.8 Flagellar basal-body P-ring formation protein FlgA compare
Pf6N2E2_5207 +0.7 1.4 hypothetical protein compare
Pf6N2E2_2597 +0.7 3.8 Flagellar regulatory protein FleQ compare
Pf6N2E2_2584 +0.7 3.5 Flagellar biosynthesis protein FliL compare
Pf6N2E2_2590 +0.7 4.3 Flagellum-specific ATP synthase FliI compare
Pf6N2E2_2585 +0.7 3.6 Flagellar hook-length control protein FliK compare
Pf6N2E2_4545 +0.7 1.6 hypothetical protein compare
Pf6N2E2_962 +0.7 1.5 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) compare
Pf6N2E2_2795 +0.7 1.4 putative exported protein compare
Pf6N2E2_5049 +0.7 1.3 acetyltransferase, GNAT family compare
Pf6N2E2_5696 +0.7 3.3 Flagellar basal-body rod modification protein FlgD compare
Pf6N2E2_4719 +0.7 3.5 Sarcosine oxidase delta subunit (EC 1.5.3.1) compare
Pf6N2E2_4367 +0.7 1.8 hypothetical protein compare
Pf6N2E2_3624 +0.7 3.0 Flagellar motor rotation protein MotB compare
Pf6N2E2_4153 +0.7 1.1 Sensory box histidine kinase compare
Pf6N2E2_2591 +0.7 2.1 Flagellar assembly protein FliH compare
Pf6N2E2_1674 +0.7 3.2 Hydroxymethylglutaryl-CoA synthase (EC 2.3.3.10) compare
Pf6N2E2_5819 +0.7 3.0 Protein-N(5)-glutamine methyltransferase PrmB, methylates LSU ribosomal protein L3p compare
Pf6N2E2_5435 +0.7 2.5 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_127 +0.7 0.8 AttE component of AttEFGH ABC transport system compare
Pf6N2E2_4907 +0.7 4.5 dTDP-4-dehydrorhamnose reductase (EC 1.1.1.133) compare
Pf6N2E2_426 +0.7 2.2 Arsenate reductase (EC 1.20.4.1) compare
Pf6N2E2_2626 +0.7 3.1 Flagellar L-ring protein FlgH compare
Pf6N2E2_2175 +0.7 1.9 Transcriptional regulator, RpiR family compare
Pf6N2E2_4263 +0.6 1.5 Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family compare
Pf6N2E2_3282 +0.6 1.6 FIG005080: Possible exported protein compare
Pf6N2E2_2627 +0.6 2.1 Flagellar basal-body rod protein FlgG compare
Pf6N2E2_2506 +0.6 4.6 nucleotide sugar epimerase/dehydratase WbpM compare
Pf6N2E2_2912 +0.6 1.3 FIG00954094: hypothetical protein compare
Pf6N2E2_2617 +0.6 3.4 dTDP-4-dehydrorhamnose 3,5-epimerase (EC 5.1.3.13) compare
Pf6N2E2_1098 +0.6 2.2 Arginine/ornithine ABC transporter, periplasmic arginine/ornithine binding protein compare
Pf6N2E2_1471 +0.6 3.3 Dienelactone hydrolase and related enzymes compare
Pf6N2E2_1548 +0.6 1.9 Lactoylglutathione lyase compare
Pf6N2E2_834 +0.6 4.0 Cation efflux system protein compare
Pf6N2E2_5025 +0.6 5.6 Sensor histidine kinase compare
Pf6N2E2_2300 +0.6 2.5 LSU rRNA 2'-O-methyl-C2498 methyltransferase RlmM compare
Pf6N2E2_3003 +0.6 1.4 Bacteriophage protein GP46 compare
Pf6N2E2_89 +0.6 1.4 hypothetical protein compare
Pf6N2E2_2211 +0.6 2.8 Hydrolase, carbon-nitrogen family compare
Pf6N2E2_1762 +0.6 1.7 putative lipase compare
Pf6N2E2_1022 +0.6 1.9 Butyryl-CoA dehydrogenase (EC 1.3.99.2) compare
Pf6N2E2_5086 +0.6 1.0 hypothetical protein compare
Pf6N2E2_4391 +0.6 2.2 D-amino acid dehydrogenase small subunit (EC 1.4.99.1) compare
Pf6N2E2_627 +0.6 3.0 2-ketogluconate 6-phosphate reductase (EC 1.1.1.43) compare
Pf6N2E2_4113 +0.6 1.0 Redox-sensing transcriptional regulator QorR compare
Pf6N2E2_664 +0.6 1.3 Acetoin catabolism protein X compare
Pf6N2E2_1605 +0.6 3.9 Carboxynorspermidine dehydrogenase, putative (EC 1.1.1.-) compare
Pf6N2E2_61 +0.6 3.2 Cys regulon transcriptional activator CysB compare
Pf6N2E2_5647 +0.6 2.7 Transcriptional regulator, TetR family compare
Pf6N2E2_1814 +0.6 1.8 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases compare
Pf6N2E2_1068 +0.6 2.7 outer membrane autotransporter compare
Pf6N2E2_3379 +0.6 4.5 Lactate-responsive regulator LldR in Enterobacteria, GntR family compare
Pf6N2E2_3663 +0.6 3.0 Glycosyl transferase compare
Pf6N2E2_2350 +0.6 1.7 Oxygen-regulated invasion protein OrgB compare
Pf6N2E2_1093 +0.6 2.4 Transcriptional regulatory protein compare
Pf6N2E2_2845 +0.6 3.7 RNA polymerase associated protein RapA (EC 3.6.1.-) compare
Pf6N2E2_1450 +0.6 1.2 FIG00960438: hypothetical protein compare
Pf6N2E2_2088 +0.6 1.1 SOS-response repressor and protease LexA (EC 3.4.21.88) compare
Pf6N2E2_1431 +0.6 1.5 Branched-chain amino acid transport system permease protein LivM (TC 3.A.1.4.1) compare
Pf6N2E2_5667 +0.6 3.2 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_669 +0.6 1.9 Nuclease inhibitor compare
Pf6N2E2_2440 +0.6 0.7 Free methionine-(R)-sulfoxide reductase, contains GAF domain compare
Pf6N2E2_414 +0.6 1.8 Chemotaxis protein CheD compare
Pf6N2E2_1092 +0.6 1.6 Probable vanillate O-demethylase oxygenase subunit oxidoreductase protein (EC 1.14.13.-) compare
Pf6N2E2_420 +0.6 1.1 Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY compare
Pf6N2E2_2677 +0.6 3.9 Small-conductance mechanosensitive channel compare
Pf6N2E2_1596 +0.6 0.8 Periplasmic nitrate reductase component NapD compare
Pf6N2E2_3589 +0.6 1.2 Lysine decarboxylase family compare


Specific Phenotypes

For 25 genes in this experiment

For carbon source Sodium propionate in Pseudomonas fluorescens FW300-N2E2

For carbon source Sodium propionate across organisms