Experiment set1IT014 for Sinorhizobium meliloti 1021

Compare to:

Sodium L-Lactate carbon source

200 most important genes:

  gene name fitness t score description  
SMc02899 -8.8 -6.1 prephenate dehydratase compare
SMc02766 -8.8 -10.5 tryptophan synthase subunit beta compare
SMc01726 -8.8 -6.1 acetylglutamate kinase compare
SMc02245 -8.3 -5.7 dihydroorotate dehydrogenase 2 compare
SMc00236 -8.2 -5.7 Indole-3-glycerol phosphate synthase compare
SMc00614 -8.1 -5.6 phosphoribosylglycinamide formyltransferase compare
SMc00917 -8.0 -5.6 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
SMc00640 -8.0 -5.5 phosphoserine aminotransferase compare
SMc00963 -8.0 -5.5 hypothetical protein compare
SMc01054 -8.0 -5.5 required for sulfate utilization, putative electron source for sulfite reductase CysI (from data) compare
SMc02569 -7.9 -5.5 imidazole glycerol phosphate synthase subunit HisF compare
SMc01801 -7.9 -5.2 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) compare
SMc04405 -7.9 -9.4 3-isopropylmalate dehydrogenase compare
SMc03797 -7.8 -9.3 homoserine O-succinyltransferase compare
SMc00235 -7.6 -7.4 anthranilate phosphoribosyltransferase compare
SMc01431 -7.6 -7.4 acetolactate synthase 3 catalytic subunit compare
SMc03069 -7.5 -4.9 6-phosphogluconolactonase compare
SMc02767 -7.4 -10.2 N-(5'-phosphoribosyl)anthranilate isomerase compare
SMc00918 -7.4 -7.2 ATP phosphoribosyltransferase regulatory subunit compare
SMc01494 -7.4 -13.9 phosphoserine phosphatase compare
SMc02725 -7.3 -12.2 anthranilate synthase compare
SMc02217 -7.3 -5.1 O-succinylhomoserine sulfhydrylase compare
SMc03895 -7.3 -15.6 pyruvate carboxylase compare
SMc01843 -7.2 -12.9 5,10-methylenetetrahydrofolate reductase compare
SMc02562 -7.1 -6.9 phosphoenolpyruvate carboxykinase compare
SMc04045 -7.1 -8.4 dihydroxy-acid dehydratase compare
SMc04002 -7.0 -7.3 phosphoribosylaminoimidazole carboxylase ATPase subunit compare
SMc01028 -6.9 -14.0 phosphopyruvate hydratase compare
SMc00711 -6.9 -6.5 cyclohexadienyl dehydrogenase compare
SMc04026 -6.9 -11.5 glutamate synthase compare
SMc00493 -6.8 -6.6 phosphoribosylformylglycinamidine synthase I compare
SMc02838 -6.7 -6.6 phosphoglyceromutase compare
SMa1635 -6.7 -2.6 hypothetical protein compare
SMc02572 -6.7 -4.7 imidazole glycerol phosphate synthase subunit HisH compare
SMc02975 -6.6 -9.7 phosphoenolpyruvate carboxykinase regulator transcription regulator protein compare
SMc00412 -6.6 -4.6 orotidine 5'-phosphate decarboxylase compare
SMc04028 -6.6 -18.1 glutamate synthase compare
SMc02765 -6.5 -11.4 tryptophan synthase subunit alpha compare
SMc02717 -6.5 -15.7 2-isopropylmalate synthase compare
SMc01004 -6.4 -10.7 phosphoribosyl-AMP cyclohydrolase compare
SMc00554 -6.4 -9.8 amidophosphoribosyltransferase compare
SMc03823 -6.3 -13.2 isopropylmalate isomerase large subunit compare
SMc00488 -6.3 -14.8 phosphoribosylformylglycinamidine synthase II compare
SMc00993 -6.1 -11.6 phosphoribosylamine--glycine ligase compare
SMc03112 -6.0 -16.5 B12-dependent methionine synthase compare
SM_b21174 -5.9 -7.2 phosphate uptake ABC transporter permease compare
SMc00495 -5.9 -7.0 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
SMc00615 -5.7 -8.7 phosphoribosylaminoimidazole synthetase compare
SMc02137 -5.7 -5.7 ornithine carbamoyltransferase compare
SMc02755 -5.7 -7.8 S-adenosyl-L-homocysteine hydrolase compare
SMc01361 -5.7 -7.8 dihydroorotase compare
SMc02165 -5.6 -10.6 orotate phosphoribosyltransferase compare
SMc03826 -5.6 -5.4 argininosuccinate synthase compare
SMc03979 -5.4 -3.7 glyceraldehyde-3-phosphate dehydrogenase compare
SMc00131 -5.4 -14.9 transcriptional regulator compare
SMc02724 -5.3 -5.2 hypothetical protein compare
SMc02124 -5.3 -16.6 nitrite reductase compare
SMc01360 -5.3 -5.1 aspartate carbamoyltransferase catalytic subunit compare
SMc02166 -5.3 -11.6 dihydroorotase compare
SMc04088 -5.2 -7.8 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase compare
SM_b21175 -5.2 -7.1 phosphate uptake ABC transporter permease compare
SMc02307 -5.2 -10.0 histidinol dehydrogenase compare
SMc01881 -5.2 -6.1 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
SMc02574 -5.1 -5.9 imidazoleglycerol-phosphate dehydratase compare
SMc03763 -5.1 -3.5 cytosine-specific methyltransferase compare
SMc03978 -5.1 -3.5 transketolase compare
SM_b21177 -5.0 -9.8 phosphate uptake ABC transporter ATP-binding protein compare
SMc00090 -5.0 -9.8 sulfate adenylyltransferase compare
SMc02123 -5.0 -5.4 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
SMc00092 -5.0 -14.8 phosphoadenosine phosphosulfate reductase compare
SMc02570 -5.0 -4.8 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
SMc01569 -4.9 -2.6 carbamoyl phosphate synthase small subunit compare
SMc00091 -4.9 -13.1 sulfate adenylyltransferase compare
SM_b20850 -4.8 -10.0 L-lactate dehydrogenase (cytochrome) (EC 1.1.2.3) (from data) conserved
SMc01880 -4.8 -4.6 pantoate--beta-alanine ligase compare
SMc04001 -4.6 -1.8 phosphoribosylaminoimidazole carboxylase catalytic subunit protein compare
SMc01770 -4.6 -2.1 serine hydroxymethyltransferase compare
SMc01215 -4.5 -4.4 carbamoyl phosphate synthase large subunit compare
SMc00017 -4.4 -2.3 homoserine kinase compare
SMc03981 -4.4 -3.0 phosphoglycerate kinase compare
SMc02246 -4.3 -1.7 hypothetical protein compare
SMc03795 -4.3 -2.3 isopropylmalate isomerase small subunit compare
SMc03070 -4.3 -9.3 glucose-6-phosphate 1-dehydrogenase compare
SM_b21176 -4.2 -6.4 phosphate uptake ABC transporter substrate-binding protein precursor compare
SMc03229 -4.2 -2.8 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase compare
SMc00494 -4.0 -3.1 phosphoribosylformylglycinamidine synthase subunit PurS compare
SMc00876 -4.0 -7.2 ATP-binding MRP protein compare
SMc01053 -3.9 -4.4 siroheme synthase compare
SMc02138 -3.6 -4.3 acetylornithine transaminase compare
SMc00293 -3.6 -9.0 homoserine dehydrogenase compare
SMc00641 -3.5 -4.3 D-3-phosphoglycerate dehydrogenase compare
SMc04346 -3.2 -3.9 ketol-acid reductoisomerase compare
SMc00450 -3.0 -2.4 protoheme IX farnesyltransferase compare
SMc02115 -2.9 -1.6 hypothetical protein compare
SMc03100 -2.7 -1.7 hypothetical protein compare
SMc00294 -2.7 -12.1 aminotransferase compare
SMc01440 -2.5 -8.7 hydrolase serine protease transmembrane protein compare
SMc00414 -2.4 -11.6 hypothetical protein compare
SMc00296 -2.3 -12.7 POLY3-hydroxybutyrate polymerase compare
SMc02858 -2.3 -1.2 chaperone protein DnaJ compare
SMc00815 -2.3 -3.2 inosine 5'-monophosphate dehydrogenase compare
SMc02983 -2.2 -8.9 ornithine, DAP, or arginine decarboxylase compare
SMc01441 -2.2 -6.4 membrane bound protease compare
SMc00295 -2.1 -2.2 hypothetical protein compare
SMc00838 -1.9 -6.7 hypothetical protein compare
SMc00010 -1.8 -2.3 cytochrome C oxidase polypeptide I transmembrane protein compare
SMc00334 -1.8 -2.4 cytidylate kinase compare
SMc01206 -1.8 -2.6 queuine tRNA-ribosyltransferase compare
SMc00356 -1.7 -7.6 lysyl-tRNA synthetase compare
SMc03974 -1.6 -6.9 hypothetical protein compare
SMc00025 -1.6 -5.9 pyruvate phosphate dikinase compare
SMc00492 -1.6 -1.4 hypothetical protein compare
SMc02683 -1.5 -2.5 hypothetical protein compare
SMc00302 -1.5 -3.2 hypothetical protein compare
SMc02141 -1.5 -5.3 phosphate transporter PhoU compare
SMc01579 -1.5 -1.6 hypothetical protein compare
SMc02058 -1.4 -2.7 YAJC protein compare
SMc00405 -1.4 -6.9 hypothetical protein compare
SMc01712 -1.4 -8.6 L-lactate dehydrogenase (cytochrome) protein compare
SMc02308 -1.4 -3.0 hypothetical protein compare
SMc02362 -1.4 -4.3 cytochrome c-type biogenesis protein CcmE compare
SMc02309 -1.3 -3.8 arsenate reductase compare
SMc02147 -1.3 -5.8 phosphate regulon sensor histidine kinase transmembrane protein compare
SMc02753 -1.3 -1.8 PTS system transporter subunit IIA compare
SMc00726 -1.3 -1.0 thiol:disulfide interchange redox-active center transmembrane protein compare
SM_b20823 -1.2 -7.8 cell surface saccharide synthesis protein compare
SMc00012 -1.2 -1.7 cytochrome C oxidase assembly protein compare
SMc00514 -1.2 -3.8 monooxygenase compare
SMa0545 -1.2 -6.7 hypothetical protein compare
SMc02641 -1.1 -3.8 UDP-glucose 6-dehydrogenase compare
SMc01337 -1.1 -1.6 hypothetical protein compare
SMc03774 -1.1 -2.8 hypothetical protein compare
SMc00987 -1.1 -3.0 hypothetical protein compare
SMc00355 -1.1 -3.6 hypothetical protein compare
SMc02140 -1.1 -1.3 phosphate regulon transcriptional regulatory protein compare
SMc00709 -1.1 -2.9 hypothetical protein compare
SMc02695 -1.1 -4.2 GTP-dependent nucleic acid-binding protein EngD compare
SMc04213 -1.1 -2.1 diacylglycerol kinase compare
SMc02172 -1.1 -5.8 transcriptional regulator compare
SM_b21633 -1.0 -1.1 enoyl-CoA hydratase compare
SMc03993 -1.0 -5.7 hypothetical protein compare
SMc00188 -1.0 -6.1 cytochrome B transmembrane protein compare
SMc04348 -1.0 -1.0 transcriptional regulator compare
SMc03834 -1.0 -1.6 pterin-4-alpha-carbinolamine dehydratase compare
SMc03776 -1.0 -2.1 gamma-glutamyl kinase compare
SMc04000 -1.0 -0.7 hypothetical protein compare
SMc01842 -1.0 -1.0 methyltransferase transcription regulator protein compare
SMc01850 -1.0 -2.7 hypothetical protein compare
SMc01933 -1.0 -1.5 hypothetical protein compare
SMc03878 -1.0 -2.7 acetoacetyl-CoA reductase compare
SMc02460 -1.0 -5.6 hypothetical protein compare
SMa0789 -1.0 -3.7 GntR family transcriptional regulator compare
SMc02897 -1.0 -2.6 cytochrome C transmembrane protein compare
SMc02142 -0.9 -4.1 phosphate transporter ATP-binding protein compare
SMc00914 -0.9 -3.3 oxidoreductase compare
SMc00009 -0.9 -3.4 cytochrome C oxidase subunit II protein compare
SMc02833 -0.9 -2.3 penicillin-insensitive murein endopeptidase compare
SMc02694 -0.9 -1.6 ATP-dependent Clp protease adaptor compare
SMc00013 -0.9 -2.1 cytochrome C oxidase subunit III transmembrane protein compare
SMc02909 -0.9 -1.2 transglycosylase transmembrane protein compare
SMa0905 -0.9 -1.3 hypothetical protein compare
SMc05009 -0.9 -1.8 nodulation protein NolR compare
SMc03850 -0.9 -1.2 heme exporter D (cytochrome C-type biogenesis protein) transmembrane compare
SMa1413 -0.9 -1.5 hypothetical protein compare
SM_b20834 -0.8 -6.3 surface saccharide synthesis protein compare
SMa1118 -0.8 -1.1 HspC2 heat shock protein compare
SMc01260 -0.8 -4.2 transcriptional regulator compare
SMc00067 -0.8 -4.7 outer-membranne lipoprotein compare
SMc02102 -0.8 -2.1 hypothetical protein compare
SMa2289 -0.8 -1.0 hypothetical protein compare
SMc01342 -0.8 -3.0 hypothetical protein compare
SM_b21524 -0.8 -2.3 septum formation inhibitor compare
SMc00622 -0.8 -4.4 ribonuclease D protein compare
SMc02145 -0.7 -0.7 signal peptide protein compare
SMa1924 -0.7 -0.8 hypothetical protein compare
SMc02361 -0.7 -2.2 cytochrome C-type biogenesis transmembrane protein compare
SMc00762 -0.7 -4.3 glutamine synthetase compare
SM_b21173 -0.7 -1.4 hypothetical protein compare
SMc01280 -0.7 -1.3 protease compare
SMc02505 -0.7 -1.4 hypothetical protein compare
SMa5015 -0.7 -2.1 hypothetical protein compare
SMa1240 -0.7 -0.8 NapF ferredoxin component of periplasmic nitrate reductase compare
SMc00691 -0.7 -2.3 site-specific tyrosine recombinase XerD compare
SMc01147 -0.7 -1.9 coproporphyrinogen III oxidase compare
SM_b20897 -0.7 -1.0 hypothetical protein compare
SMc00189 -0.7 -4.0 cytochrome C1 protein compare
SMc04327 -0.7 -0.9 hypothetical protein compare
SMa1367 -0.7 -2.2 short chain alcohol dehydrogenase-related dehydrogenase compare
SMc02861 -0.7 -1.9 phosphate transporter compare
SMa0874 -0.7 -1.8 NodN dehydratase compare
SMc02227 -0.7 -3.5 fatty oxidation complex enoyl-COA hydratase/3-hydroxyacyl-COA dehydrogenase/3-hydroxybutyryl-COA epimerase compare
SMc02868 -0.7 -2.4 multidrug efflux system protein compare
SMc03980 -0.7 -2.2 hypothetical protein compare
SMc01501 -0.7 -2.3 mannitol 2-dehydrogenase compare
SMc02690 -0.6 -2.4 hypothetical protein compare
SMc03128 -0.6 -1.4 ABC transporter permease compare
SM_b21261 -0.6 -5.2 mureinpeptideoligopeptide ABC transporter substrate-binding protein precursor compare
SM_b20397 -0.6 -2.0 oxidoreductase compare
SMc04296 -0.6 -1.0 cell division protein FtsZ compare
SMa1398 -0.6 -1.7 3-ketoacyl-ACP reductase compare


Specific Phenotypes

For 3 genes in this experiment

For carbon source Sodium L-Lactate in Sinorhizobium meliloti 1021

For carbon source Sodium L-Lactate across organisms