Experiment set1IT012 for Pseudomonas fluorescens FW300-N2E2

Compare to:

Sodium pyruvate carbon source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_4597 -6.6 -10.1 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_3253 -6.4 -6.3 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_4825 -6.3 -9.6 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_4596 -6.3 -11.3 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_77 -6.2 -6.0 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_3630 -5.7 -8.3 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_5175 -5.6 -18.5 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_2277 -5.5 -3.8 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_3839 -5.4 -6.4 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_4826 -5.4 -8.9 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_3610 -5.4 -7.2 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_64 -5.2 -5.3 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_4047 -5.2 -7.2 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_3751 -5.2 -17.4 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_3783 -5.1 -7.1 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_5176 -4.9 -14.2 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_4048 -4.9 -9.2 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_3842 -4.9 -7.5 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_5156 -4.7 -3.2 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_66 -4.5 -10.7 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_4638 -4.5 -4.4 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_2073 -4.4 -10.1 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_3752 -4.3 -19.2 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_3248 -4.3 -4.9 Probable transmembrane protein compare
Pf6N2E2_3782 -4.2 -5.7 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_4564 -4.2 -8.4 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_3841 -4.1 -6.2 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_71 -4.1 -9.4 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_302 -4.0 -9.0 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_5177 -3.9 -7.6 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_4278 -3.8 -11.4 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_3252 -3.8 -7.0 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_3932 -3.8 -5.5 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_3940 -3.7 -10.4 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_5666 -3.6 -12.6 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_4279 -3.3 -14.9 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_1294 -3.3 -3.4 Carbon starvation protein A compare
Pf6N2E2_1296 -3.2 -8.9 DNA-binding response regulator, LuxR family conserved
Pf6N2E2_4277 -3.1 -10.3 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_4759 -3.0 -15.3 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_1400 -3.0 -13.0 Sensory box histidine kinase/response regulator compare
Pf6N2E2_2217 -2.9 -8.6 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_5579 -2.9 -8.0 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_1381 -2.8 -9.5 Aldehyde dehydrogenase (EC 1.2.1.3) compare
Pf6N2E2_5006 -2.7 -8.4 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_2753 -2.7 -4.5 HtrA protease/chaperone protein compare
Pf6N2E2_63 -2.6 -4.4 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_2074 -2.6 -2.1 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_3170 -2.5 -6.7 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_5014 -2.5 -2.1 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_3251 -2.3 -9.4 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_2465 -2.2 -5.6 Cys regulon transcriptional activator CysB compare
Pf6N2E2_4764 -2.2 -6.9 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_3984 -2.2 -9.6 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_4372 -2.2 -6.4 FIG00460773: hypothetical protein compare
Pf6N2E2_1295 -2.1 -6.5 Sensor histidine kinase conserved
Pf6N2E2_50 -2.1 -8.6 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_2514 -2.1 -5.1 regulator of length of O-antigen component of lipopolysaccharide chains compare
Pf6N2E2_4803 -2.0 -2.6 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_4009 -2.0 -11.0 GGDEF domain protein compare
Pf6N2E2_5527 -2.0 -2.5 Cold shock protein CspC compare
Pf6N2E2_1402 -2.0 -4.8 hypothetical protein compare
Pf6N2E2_5242 -1.9 -2.7 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_4761 -1.8 -8.7 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf6N2E2_5667 -1.8 -6.6 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_4763 -1.8 -8.9 Biotin synthesis protein BioC compare
Pf6N2E2_4204 -1.8 -1.9 rRNA small subunit 7-methylguanosine (m7G) methyltransferase GidB compare
Pf6N2E2_3569 -1.8 -3.6 hypothetical protein compare
Pf6N2E2_4631 -1.7 -7.5 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf6N2E2_5728 -1.7 -3.3 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_2574 -1.6 -3.6 Flagellar synthesis regulator FleN compare
Pf6N2E2_2010 -1.6 -2.7 hypothetical protein compare
Pf6N2E2_2186 -1.6 -6.0 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
Pf6N2E2_2313 -1.6 -4.6 Cytochrome c oxidase subunit CcoP (EC 1.9.3.1) compare
Pf6N2E2_248 -1.6 -6.9 hypothetical protein compare
Pf6N2E2_2218 -1.5 -4.6 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_4579 -1.5 -2.5 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
Pf6N2E2_5103 -1.5 -2.2 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
Pf6N2E2_4165 -1.4 -5.5 Zinc ABC transporter, periplasmic-binding protein ZnuA conserved
Pf6N2E2_5252 -1.4 -2.8 FIG00956396: hypothetical protein compare
Pf6N2E2_3349 -1.3 -2.4 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_2318 -1.3 -6.5 Type cbb3 cytochrome oxidase biogenesis protein CcoI; Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_5316 -1.3 -1.9 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_2317 -1.3 -4.8 Putative analog of CcoH, COG3198 compare
Pf6N2E2_5553 -1.3 -7.0 Quinolinate synthetase (EC 2.5.1.72) compare
Pf6N2E2_3938 -1.2 -9.5 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf6N2E2_3039 -1.2 -5.0 Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) compare
Pf6N2E2_2320 -1.2 -3.6 Heavy-metal-associated domain (N-terminus) and membrane-bounded cytochrome biogenesis cycZ-like domain, possible membrane copper tolerance protein compare
Pf6N2E2_1293 -1.2 -2.0 COG2879, Hypothetical small protein yjiX compare
Pf6N2E2_4743 -1.2 -1.2 hypothetical protein compare
Pf6N2E2_2309 -1.2 -2.4 hypothetical protein compare
Pf6N2E2_5780 -1.2 -6.1 Periplasmic protease compare
Pf6N2E2_178 -1.2 -1.3 Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) compare
Pf6N2E2_2674 -1.1 -1.4 FIG00953856: hypothetical protein compare
Pf6N2E2_3062 -1.1 -4.9 Membrane-associated zinc metalloprotease compare
Pf6N2E2_2586 -1.1 -2.1 Hpt domain protein compare
Pf6N2E2_6140 -1.1 -1.2 Large Subunit Ribosomal RNA; lsuRNA; LSU rRNA compare
Pf6N2E2_3271 -1.1 -2.4 Phosphocarrier protein, nitrogen regulation associated compare
Pf6N2E2_4206 -1.1 -2.2 Chromosome (plasmid) partitioning protein ParB compare
Pf6N2E2_2473 -1.1 -1.5 Major outer membrane lipoprotein I compare
Pf6N2E2_1401 -1.1 -2.9 FIG00955631: hypothetical protein compare
Pf6N2E2_2156 -1.1 -2.7 Putative polyketide synthase (Fragment) compare
Pf6N2E2_4168 -1.1 -4.9 Zinc ABC transporter, inner membrane permease protein ZnuB compare
Pf6N2E2_4205 -1.1 -3.2 Chromosome (plasmid) partitioning protein ParA compare
Pf6N2E2_2310 -1.1 -7.1 Cytochrome c oxidase subunit CcoN (EC 1.9.3.1) compare
Pf6N2E2_2311 -1.1 -5.9 Cytochrome c oxidase subunit CcoO (EC 1.9.3.1) compare
Pf6N2E2_4417 -1.0 -2.8 Protein of unknown function DUF484 compare
Pf6N2E2_3460 -1.0 -1.8 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_4305 -1.0 -1.4 FIG00959590: hypothetical protein compare
Pf6N2E2_5258 -1.0 -3.8 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_1932 -1.0 -3.3 Transcriptional regulator, IclR family compare
Pf6N2E2_5676 -1.0 -3.1 Aspartokinase (EC 2.7.2.4) compare
Pf6N2E2_5848 -1.0 -2.5 small component of pyruvate transporter (yjcH-like) (from data) compare
Pf6N2E2_5153 -1.0 -4.4 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) compare
Pf6N2E2_3461 -1.0 -1.0 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_189 -1.0 -3.1 regulatory protein, putative compare
Pf6N2E2_5190 -0.9 -7.0 Carbonic anhydrase (EC 4.2.1.1) compare
Pf6N2E2_4077 -0.9 -2.3 cytosolic long-chain acyl-CoA thioester hydrolase family protein compare
Pf6N2E2_2285 -0.9 -1.6 FIG00954079: hypothetical protein compare
Pf6N2E2_5849 -0.9 -7.0 large component of pyruvate transporter (actP-like) (from data) conserved
Pf6N2E2_1718 -0.9 -2.1 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) compare
Pf6N2E2_4453 -0.9 -7.7 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_4167 -0.9 -5.2 Zinc ABC transporter, ATP-binding protein ZnuC compare
Pf6N2E2_2752 -0.9 -5.2 Exported zinc metalloprotease YfgC precursor compare
Pf6N2E2_5111 -0.9 -2.1 FKBP-type peptidyl-prolyl cis-trans isomerase SlpA (EC 5.2.1.8) compare
Pf6N2E2_5219 -0.9 -6.1 FIG140336: TPR domain protein compare
Pf6N2E2_3258 -0.8 -4.0 Uncharacterized ABC transporter, periplasmic component YrbD compare
Pf6N2E2_5936 -0.8 -2.2 Low molecular weight protein tyrosine phosphatase (EC 3.1.3.48) compare
Pf6N2E2_3060 -0.8 -1.9 Outer membrane protein H precursor compare
Pf6N2E2_3346 -0.8 -3.3 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf6N2E2_5080 -0.8 -5.0 Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family compare
Pf6N2E2_4367 -0.8 -2.1 hypothetical protein compare
Pf6N2E2_3672 -0.8 -5.8 Glutamate-ammonia-ligase adenylyltransferase (EC 2.7.7.42) compare
Pf6N2E2_3847 -0.8 -3.2 FIG001341: Probable Fe(2+)-trafficking protein YggX compare
Pf6N2E2_1717 -0.8 -5.4 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
Pf6N2E2_5406 -0.8 -1.4 FIG00958224: hypothetical protein compare
Pf6N2E2_99 -0.8 -2.0 hypothetical protein compare
Pf6N2E2_3942 -0.8 -4.7 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
Pf6N2E2_4773 -0.8 -0.8 Coenzyme PQQ synthesis protein D compare
Pf6N2E2_5345 -0.8 -4.3 LppC putative lipoprotein compare
Pf6N2E2_5331 -0.8 -4.5 ATPase, AFG1 family compare
Pf6N2E2_1821 -0.8 -1.6 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system compare
Pf6N2E2_2312 -0.8 -1.8 Cytochrome c oxidase subunit CcoQ (EC 1.9.3.1) compare
Pf6N2E2_4824 -0.8 -2.1 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
Pf6N2E2_4454 -0.8 -3.1 Exopolyphosphatase (EC 3.6.1.11) compare
Pf6N2E2_5157 -0.8 -4.5 Two-component sensor CbrA: intrcellular carbon:nitrogen balance compare
Pf6N2E2_3820 -0.8 -0.9 hypothetical protein compare
Pf6N2E2_5078 -0.8 -1.2 Carbon starvation protein A compare
Pf6N2E2_5257 -0.8 -4.3 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_3096 -0.7 -1.1 Periplasmic protein TonB, links inner and outer membranes compare
Pf6N2E2_1723 -0.7 -2.6 Transcriptional regulator, TetR family compare
Pf6N2E2_3807 -0.7 -2.4 Histidine utilization repressor compare
Pf6N2E2_4963 -0.7 -0.9 Homoserine dehydrogenase (EC 1.1.1.3) compare
Pf6N2E2_5520 -0.7 -3.6 Sensory box histidine kinase compare
Pf6N2E2_3192 -0.7 -2.3 tRNA:Cm32/Um32 methyltransferase compare
Pf6N2E2_2501 -0.7 -2.3 hypothetical protein compare
Pf6N2E2_1784 -0.7 -2.4 Methyl-accepting chemotaxis protein compare
Pf6N2E2_2012 -0.7 -1.8 hypothetical protein compare
Pf6N2E2_5665 -0.7 -3.0 Succinylornithine transaminase (EC 2.6.1.81) compare
Pf6N2E2_3761 -0.7 -6.3 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) compare
Pf6N2E2_4797 -0.7 -1.4 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_3723 -0.7 -1.9 FIG022199: FAD-binding protein compare
Pf6N2E2_5950 -0.7 -2.8 Phosphate:acyl-ACP acyltransferase PlsX compare
Pf6N2E2_4762 -0.7 -1.5 Biotin synthesis protein BioH compare
Pf6N2E2_5990 -0.7 -1.8 Translation initiation factor 2 (IF-2; GTPase) compare
Pf6N2E2_4392 -0.7 -1.4 Translation initiation inhibitor compare
Pf6N2E2_5337 -0.7 -2.2 Ubiquinol-cytochrome C reductase iron-sulfur subunit (EC 1.10.2.2) compare
Pf6N2E2_2477 -0.7 -1.4 ABC transporter ATP-binding protein YvcR compare
Pf6N2E2_51 -0.7 -3.2 hypothetical protein compare
Pf6N2E2_933 -0.6 -2.8 Glutathione S-transferase (EC 2.5.1.18) compare
Pf6N2E2_3237 -0.6 -2.2 hypothetical protein compare
Pf6N2E2_623 -0.6 -1.0 FIG00954674: hypothetical protein compare
Pf6N2E2_5262 -0.6 -1.4 FKBP-type peptidyl-prolyl cis-trans isomerase SlyD (EC 5.2.1.8) compare
Pf6N2E2_4080 -0.6 -2.6 FIG00953722: hypothetical protein compare
Pf6N2E2_3835 -0.6 -2.2 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf6N2E2_3719 -0.6 -3.4 FIG002571: 4-hydroxybenzoyl-CoA thioesterase domain protein compare
Pf6N2E2_282 -0.6 -1.1 GNAT family acetyltransferase YjcF compare
Pf6N2E2_1605 -0.6 -4.0 Carboxynorspermidine dehydrogenase, putative (EC 1.1.1.-) compare
Pf6N2E2_1606 -0.6 -3.1 Carboxynorspermidine decarboxylase, putative (EC 4.1.1.-) compare
Pf6N2E2_3869 -0.6 -4.2 Branched-chain amino acid transport protein AzlC compare
Pf6N2E2_288 -0.6 -1.4 Isocitrate dehydrogenase [NADP] (EC 1.1.1.42); Monomeric isocitrate dehydrogenase [NADP] (EC 1.1.1.42) compare
Pf6N2E2_3840 -0.6 -1.4 FIG00956267: hypothetical protein compare
Pf6N2E2_5430 -0.6 -4.4 Transglycosylase, Slt family compare
Pf6N2E2_4298 -0.6 -1.7 Uncharacterized protein ImpB compare
Pf6N2E2_1412 -0.6 -2.2 hypothetical protein compare
Pf6N2E2_2675 -0.6 -0.7 ATP-dependent RNA helicase SrmB compare
Pf6N2E2_1147 -0.6 -1.5 Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) compare
Pf6N2E2_574 -0.6 -1.8 Transporter, LysE family compare
Pf6N2E2_4162 -0.6 -1.7 DNA polymerase I (EC 2.7.7.7) compare
Pf6N2E2_1894 -0.6 -2.7 hypothetical protein compare
Pf6N2E2_1776 -0.6 -1.9 Chemotaxis protein CheD compare
Pf6N2E2_3183 -0.6 -2.0 Believed to be involved in assembly of Fe-S clusters compare
Pf6N2E2_2756 -0.6 -3.8 RNA polymerase sigma-H factor AlgT compare
Pf6N2E2_2072 -0.6 -1.2 hypothetical protein compare
Pf6N2E2_5030 -0.6 -3.4 Transcriptional regulator, AsnC family compare
Pf6N2E2_2316 -0.6 -4.3 Type cbb3 cytochrome oxidase biogenesis protein CcoG, involved in Cu oxidation compare
Pf6N2E2_3040 -0.6 -2.7 5-nucleotidase SurE (EC 3.1.3.5) compare
Pf6N2E2_3641 -0.6 -1.9 ADP-ribose pyrophosphatase (EC 3.6.1.13) compare
Pf6N2E2_1182 -0.6 -2.0 Transcriptional regulator, LysR family compare
Pf6N2E2_3826 -0.6 -2.4 Nitrogen regulation protein NR(I) compare


Specific Phenotypes

For 4 genes in this experiment

For carbon source Sodium pyruvate in Pseudomonas fluorescens FW300-N2E2

For carbon source Sodium pyruvate across organisms