Experiment set1IT011 for Pseudomonas fluorescens FW300-N2E2

Compare to:

Sodium D,L-Lactate carbon source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_64 -7.3 -5.0 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_3842 -7.0 -4.9 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_4597 -6.5 -10.0 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_77 -6.0 -5.9 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_4279 -5.7 -15.6 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_4596 -5.7 -13.2 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_3630 -5.6 -8.5 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_5175 -5.6 -17.5 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_4826 -5.5 -9.8 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_3751 -5.3 -17.0 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_3382 -5.3 -10.1 Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF compare
Pf6N2E2_3248 -5.3 -7.0 Probable transmembrane protein compare
Pf6N2E2_4047 -5.2 -7.1 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_4278 -5.1 -15.5 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_5176 -5.0 -13.4 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_4759 -5.0 -19.5 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_3841 -4.9 -7.4 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_3384 -4.8 -7.4 Predicted L-lactate dehydrogenase, hypothetical protein subunit YkgG compare
Pf6N2E2_4825 -4.7 -12.2 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_3782 -4.7 -7.1 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_5177 -4.7 -11.1 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_3839 -4.6 -7.0 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_4762 -4.6 -5.4 Biotin synthesis protein BioH compare
Pf6N2E2_3932 -4.5 -7.9 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_71 -4.5 -7.3 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_2074 -4.5 -2.9 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_3752 -4.5 -20.7 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_3381 -4.5 -11.8 Predicted L-lactate dehydrogenase, Fe-S oxidoreductase subunit YkgE compare
Pf6N2E2_2277 -4.4 -4.2 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_2073 -4.3 -9.6 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_4564 -4.3 -7.9 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_3380 -4.3 -10.7 L-lactate permease compare
Pf6N2E2_3610 -4.1 -6.6 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_4764 -4.0 -8.7 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_302 -3.9 -6.0 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_3940 -3.9 -9.7 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_3783 -3.9 -6.8 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_3253 -3.8 -8.9 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_66 -3.8 -9.1 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_3383 -3.8 -7.1 Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF compare
Pf6N2E2_4638 -3.7 -5.6 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_4277 -3.6 -8.8 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_5666 -3.5 -12.3 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_4631 -3.5 -9.0 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf6N2E2_4048 -3.4 -6.5 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_5006 -3.4 -10.5 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_4761 -3.4 -13.0 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf6N2E2_3252 -3.4 -7.3 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_3251 -3.2 -13.4 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_4763 -3.1 -11.5 Biotin synthesis protein BioC compare
Pf6N2E2_5579 -3.0 -7.9 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_3170 -2.8 -7.2 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_5156 -2.7 -4.5 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_63 -2.7 -3.8 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_5728 -2.6 -5.1 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_2753 -2.6 -5.2 HtrA protease/chaperone protein compare
Pf6N2E2_2465 -2.5 -5.0 Cys regulon transcriptional activator CysB compare
Pf6N2E2_50 -2.3 -8.5 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_5527 -2.3 -3.5 Cold shock protein CspC compare
Pf6N2E2_4797 -2.2 -2.7 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_4009 -2.1 -9.1 GGDEF domain protein compare
Pf6N2E2_5667 -2.1 -7.4 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_3984 -2.1 -10.0 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_2313 -2.0 -5.0 Cytochrome c oxidase subunit CcoP (EC 1.9.3.1) compare
Pf6N2E2_248 -2.0 -7.7 hypothetical protein compare
Pf6N2E2_2217 -1.9 -6.9 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_5676 -1.9 -3.3 Aspartokinase (EC 2.7.2.4) compare
Pf6N2E2_2514 -1.9 -4.6 regulator of length of O-antigen component of lipopolysaccharide chains compare
Pf6N2E2_2640 -1.8 -3.3 Permease of the drug/metabolite transporter (DMT) superfamily compare
Pf6N2E2_3534 -1.8 -2.7 Cobalamin biosynthesis protein CobG compare
Pf6N2E2_3899 -1.8 -8.5 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) compare
Pf6N2E2_3661 -1.8 -5.1 hypothetical protein compare
Pf6N2E2_3938 -1.6 -10.5 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf6N2E2_5190 -1.6 -10.1 Carbonic anhydrase (EC 4.2.1.1) compare
Pf6N2E2_4205 -1.6 -4.7 Chromosome (plasmid) partitioning protein ParA compare
Pf6N2E2_4204 -1.5 -1.6 rRNA small subunit 7-methylguanosine (m7G) methyltransferase GidB compare
Pf6N2E2_2065 -1.5 -3.2 Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) compare
Pf6N2E2_5014 -1.5 -1.7 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_4417 -1.4 -4.2 Protein of unknown function DUF484 compare
Pf6N2E2_2473 -1.4 -1.8 Major outer membrane lipoprotein I compare
Pf6N2E2_5103 -1.4 -1.5 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
Pf6N2E2_3346 -1.4 -4.6 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf6N2E2_4059 -1.4 -1.5 DNA-binding protein HU-alpha compare
Pf6N2E2_5257 -1.3 -7.3 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_51 -1.3 -5.6 hypothetical protein compare
Pf6N2E2_5746 -1.3 -2.6 Cobalamin synthase compare
Pf6N2E2_5258 -1.3 -5.6 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_5155 -1.3 -2.9 Poly(A) polymerase (EC 2.7.7.19) compare
Pf6N2E2_4372 -1.3 -3.4 FIG00460773: hypothetical protein compare
Pf6N2E2_4206 -1.2 -1.5 Chromosome (plasmid) partitioning protein ParB compare
Pf6N2E2_4159 -1.2 -3.3 Cytochrome c4 compare
Pf6N2E2_2318 -1.2 -7.0 Type cbb3 cytochrome oxidase biogenesis protein CcoI; Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_156 -1.2 -2.8 Carbon storage regulator compare
Pf6N2E2_5553 -1.2 -5.2 Quinolinate synthetase (EC 2.5.1.72) compare
Pf6N2E2_4181 -1.2 -1.5 Organic hydroperoxide resistance protein compare
Pf6N2E2_5950 -1.1 -3.4 Phosphate:acyl-ACP acyltransferase PlsX compare
Pf6N2E2_3349 -1.1 -2.7 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_3533 -1.1 -4.2 Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) compare
Pf6N2E2_3040 -1.1 -4.7 5-nucleotidase SurE (EC 3.1.3.5) compare
Pf6N2E2_3385 -1.1 -7.0 Predicted D-lactate dehydrogenase, Fe-S protein, FAD/FMN-containing compare
Pf6N2E2_3557 -1.1 -2.7 Chaperone-modulator protein CbpM compare
Pf6N2E2_4579 -1.1 -1.7 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
Pf6N2E2_2310 -1.1 -6.8 Cytochrome c oxidase subunit CcoN (EC 1.9.3.1) compare
Pf6N2E2_4454 -1.1 -4.4 Exopolyphosphatase (EC 3.6.1.11) compare
Pf6N2E2_2286 -1.1 -2.1 FIG00953287: hypothetical protein compare
Pf6N2E2_3569 -1.1 -1.9 hypothetical protein compare
Pf6N2E2_5665 -1.0 -4.2 Succinylornithine transaminase (EC 2.6.1.81) compare
Pf6N2E2_423 -1.0 -2.6 Putative phosphatase YfbT compare
Pf6N2E2_2320 -1.0 -3.2 Heavy-metal-associated domain (N-terminus) and membrane-bounded cytochrome biogenesis cycZ-like domain, possible membrane copper tolerance protein compare
Pf6N2E2_1617 -1.0 -1.2 COG2199: FOG: GGDEF domain compare
Pf6N2E2_70 -1.0 -3.4 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
Pf6N2E2_2309 -1.0 -1.7 hypothetical protein compare
Pf6N2E2_3869 -1.0 -6.0 Branched-chain amino acid transport protein AzlC compare
Pf6N2E2_4453 -1.0 -7.9 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_2068 -1.0 -5.6 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) compare
Pf6N2E2_5252 -1.0 -2.1 FIG00956396: hypothetical protein compare
Pf6N2E2_3198 -0.9 -1.2 tRNA-guanine transglycosylase (EC 2.4.2.29) compare
Pf6N2E2_1717 -0.9 -5.5 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
Pf6N2E2_5001 -0.9 -1.2 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) compare
Pf6N2E2_728 -0.9 -2.6 Nitrate/nitrite transporter compare
Pf6N2E2_2062 -0.9 -2.6 FIG00955561: hypothetical protein compare
Pf6N2E2_2186 -0.9 -3.9 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
Pf6N2E2_4476 -0.9 -3.8 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) compare
Pf6N2E2_4071 -0.9 -2.9 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_3039 -0.9 -4.6 Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) compare
Pf6N2E2_4464 -0.9 -2.0 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases / CDP-6-deoxy-delta-3,4-glucoseen reductase-like compare
Pf6N2E2_2527 -0.9 -3.8 Oxidoreductase, short chain dehydrogenase/reductase family compare
Pf6N2E2_4640 -0.9 -1.5 hypothetical protein compare
Pf6N2E2_3835 -0.9 -3.3 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf6N2E2_2311 -0.9 -4.3 Cytochrome c oxidase subunit CcoO (EC 1.9.3.1) compare
Pf6N2E2_5669 -0.9 -4.5 Succinylarginine dihydrolase (EC 3.5.3.23) compare
Pf6N2E2_5714 -0.9 -2.2 Flavoprotein WrbA compare
Pf6N2E2_2389 -0.9 -5.6 Phosphoenolpyruvate synthase (EC 2.7.9.2) conserved
Pf6N2E2_4743 -0.9 -1.0 hypothetical protein compare
Pf6N2E2_178 -0.9 -1.1 Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) compare
Pf6N2E2_4824 -0.8 -2.5 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
Pf6N2E2_1236 -0.8 -2.2 Transcriptional regulator, LysR family compare
Pf6N2E2_2317 -0.8 -2.8 Putative analog of CcoH, COG3198 compare
Pf6N2E2_3085 -0.8 -2.4 FIG00954614: hypothetical protein compare
Pf6N2E2_2088 -0.8 -1.8 SOS-response repressor and protease LexA (EC 3.4.21.88) compare
Pf6N2E2_1667 -0.8 -2.2 Fumarylacetoacetate hydrolase family protein compare
Pf6N2E2_3532 -0.8 -4.1 Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130) compare
Pf6N2E2_3638 -0.8 -1.6 hypothetical protein compare
Pf6N2E2_3807 -0.8 -2.6 Histidine utilization repressor compare
Pf6N2E2_3537 -0.8 -2.4 Cobalt-precorrin-6x reductase (EC 1.3.1.54) compare
Pf6N2E2_4038 -0.8 -5.1 NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2) compare
Pf6N2E2_3338 -0.8 -1.8 1-phosphofructokinase (EC 2.7.1.56) compare
Pf6N2E2_4451 -0.8 -3.6 FIG139438: lipoprotein B compare
Pf6N2E2_1718 -0.8 -2.5 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) compare
Pf6N2E2_623 -0.8 -1.2 FIG00954674: hypothetical protein compare
Pf6N2E2_3055 -0.8 -2.2 Ribonuclease HII (EC 3.1.26.4) compare
Pf6N2E2_2984 -0.8 -1.0 LysR family transcriptional regulator PA3398 compare
Pf6N2E2_4040 -0.8 -5.9 NAD(P) transhydrogenase subunit beta (EC 1.6.1.2) compare
Pf6N2E2_5030 -0.8 -4.2 Transcriptional regulator, AsnC family compare
Pf6N2E2_5743 -0.8 -3.3 Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) compare
Pf6N2E2_4165 -0.8 -3.7 Zinc ABC transporter, periplasmic-binding protein ZnuA compare
Pf6N2E2_2447 -0.8 -4.4 Probable protease htpX homolog (EC 3.4.24.-) compare
Pf6N2E2_5613 -0.8 -2.2 FIG00953674: hypothetical protein compare
Pf6N2E2_5841 -0.8 -1.1 GlcG protein compare
Pf6N2E2_1095 -0.7 -1.3 Opine oxidase subunit C compare
Pf6N2E2_3062 -0.7 -1.8 Membrane-associated zinc metalloprotease compare
Pf6N2E2_754 -0.7 -1.2 Histone acetyltransferase HPA2 and related acetyltransferases compare
Pf6N2E2_3607 -0.7 -4.1 3'-to-5' exoribonuclease RNase R compare
Pf6N2E2_3283 -0.7 -3.2 Cytoplasmic axial filament protein CafA and Ribonuclease G (EC 3.1.4.-) compare
Pf6N2E2_1705 -0.7 -1.4 Branched-chain amino acid transport ATP-binding protein LivG (TC 3.A.1.4.1) compare
Pf6N2E2_5742 -0.7 -4.2 Cobyric acid synthase (EC 6.3.5.10) compare
Pf6N2E2_5219 -0.7 -4.1 FIG140336: TPR domain protein compare
Pf6N2E2_3475 -0.7 -1.6 hypothetical protein compare
Pf6N2E2_3906 -0.7 -4.8 Transcription accessory protein (S1 RNA-binding domain) compare
Pf6N2E2_4039 -0.7 -3.8 NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2) compare
Pf6N2E2_2281 -0.7 -1.8 Beta N-acetyl-glucosaminidase (EC 3.2.1.52) compare
Pf6N2E2_4162 -0.7 -1.5 DNA polymerase I (EC 2.7.7.7) compare
Pf6N2E2_3868 -0.7 -3.8 Transcriptional regulator, LysR family compare
Pf6N2E2_5520 -0.7 -3.2 Sensory box histidine kinase compare
Pf6N2E2_3293 -0.7 -1.2 4-carboxymuconolactone decarboxylase (EC 4.1.1.44) compare
Pf6N2E2_2842 -0.7 -2.0 hypothetical protein compare
Pf6N2E2_2060 -0.7 -4.6 CobN component of cobalt chelatase involved in B12 biosynthesis compare
Pf6N2E2_3535 -0.7 -3.5 Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-) compare
Pf6N2E2_1031 -0.7 -2.2 Alkanesulfonates transport system permease protein compare
Pf6N2E2_2442 -0.7 -4.8 sensor histidine kinase/response regulator compare
Pf6N2E2_2675 -0.7 -0.8 ATP-dependent RNA helicase SrmB compare
Pf6N2E2_2059 -0.7 -2.6 ChlI component of cobalt chelatase involved in B12 biosynthesis compare
Pf6N2E2_3885 -0.7 -2.2 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
Pf6N2E2_2756 -0.7 -3.5 RNA polymerase sigma-H factor AlgT compare
Pf6N2E2_5967 -0.6 -1.8 L-arabinose 1-dehydrogenase / D-galactose 1-dehydrogenase (EC 1.1.1.46; EC 1.1.1.48) (from data) compare
Pf6N2E2_5186 -0.6 -4.5 FIG00954491: hypothetical protein compare
Pf6N2E2_1281 -0.6 -2.2 ATPase involved in DNA repair compare
Pf6N2E2_2534 -0.6 -2.3 Cell division protein BolA compare
Pf6N2E2_5955 -0.6 -2.9 Aminodeoxychorismate lyase (EC 4.1.3.38) compare
Pf6N2E2_3134 -0.6 -0.8 hypothetical protein compare
Pf6N2E2_1606 -0.6 -2.9 Carboxynorspermidine decarboxylase, putative (EC 4.1.1.-) compare
Pf6N2E2_3255 -0.6 -2.0 YrbA protein compare
Pf6N2E2_3870 -0.6 -1.1 hypothetical protein compare
Pf6N2E2_1917 -0.6 -1.9 hypothetical protein compare
Pf6N2E2_338 -0.6 -1.4 Transcriptional regulator, AraC family compare
Pf6N2E2_841 -0.6 -2.2 hypothetical protein compare
Pf6N2E2_3826 -0.6 -2.9 Nitrogen regulation protein NR(I) compare
Pf6N2E2_4331 -0.6 -1.6 hypothetical protein compare
Pf6N2E2_2064 -0.6 -1.7 Cobalt-precorrin-3b C17-methyltransferase compare
Pf6N2E2_2674 -0.6 -0.9 FIG00953856: hypothetical protein compare


Specific Phenotypes

None in this experiment

For Pseudomonas fluorescens FW300-N2E2 in carbon source experiments

For carbon source Sodium D,L-Lactate across organisms