Experiment set1IT011 for Pseudomonas fluorescens FW300-N1B4

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a-Ketoglutaric acid disodium salt hydrate carbon source

200 most important genes:

  gene name fitness t score description  
Pf1N1B4_6 -4.6 -3.2 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf1N1B4_1067 -4.0 -6.7 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf1N1B4_1307 -3.7 -2.6 3-dehydroquinate dehydratase II (EC 4.2.1.10) compare
Pf1N1B4_2880 -3.7 -12.5 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf1N1B4_1831 -3.7 -11.2 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf1N1B4_2549 -3.6 -9.9 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf1N1B4_2547 -3.6 -3.5 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
Pf1N1B4_1627 -3.6 -4.8 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf1N1B4_15 -3.5 -4.8 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf1N1B4_2879 -3.5 -7.0 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf1N1B4_2303 -3.4 -14.8 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf1N1B4_2272 -3.4 -4.0 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf1N1B4_1534 -3.4 -18.7 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf1N1B4_2545 -3.4 -14.0 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
Pf1N1B4_12 -3.2 -8.2 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf1N1B4_5665 -3.1 -6.2 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf1N1B4_2858 -3.1 -11.5 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf1N1B4_1533 -3.1 -8.8 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf1N1B4_847 -3.1 -10.3 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf1N1B4_3917 -3.0 -5.3 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf1N1B4_1626 -3.0 -8.1 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf1N1B4_1624 -3.0 -9.8 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf1N1B4_684 -2.9 -6.9 C4-dicarboxylate transport sensor protein conserved
Pf1N1B4_1408 -2.9 -5.1 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf1N1B4_3812 -2.8 -9.4 Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) compare
Pf1N1B4_742 -2.8 -9.1 Argininosuccinate synthase (EC 6.3.4.5) compare
Pf1N1B4_3506 -2.8 -8.2 Cysteine synthase B (EC 2.5.1.47) compare
Pf1N1B4_2338 -2.8 -8.4 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf1N1B4_1830 -2.8 -9.3 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf1N1B4_2384 -2.8 -10.5 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf1N1B4_2548 -2.7 -7.9 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf1N1B4_5666 -2.7 -3.6 Oxidoreductase probably involved in sulfite reduction compare
Pf1N1B4_2337 -2.7 -5.5 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf1N1B4_1434 -2.7 -8.3 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf1N1B4_2878 -2.7 -8.9 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf1N1B4_686 -2.7 -9.2 Dicarboxylate MFS transporter conserved
Pf1N1B4_3697 -2.6 -9.1 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf1N1B4_1565 -2.6 -5.1 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf1N1B4_350 -2.5 -7.5 Chorismate mutase I (EC 5.4.99.5) / Prephenate dehydratase (EC 4.2.1.51) compare
Pf1N1B4_1545 -2.5 -10.8 NADP-dependent malic enzyme (EC 1.1.1.40) compare
Pf1N1B4_2112 -2.4 -14.0 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
Pf1N1B4_1617 -2.4 -8.2 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (EC 5.4.2.1) compare
Pf1N1B4_1315 -2.3 -8.6 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) compare
Pf1N1B4_2282 -2.3 -9.2 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf1N1B4_4065 -2.3 -8.3 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf1N1B4_762 -2.2 -6.7 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf1N1B4_2859 -2.0 -13.4 Two-component sensor CbrA: intrcellular carbon:nitrogen balance compare
Pf1N1B4_1625 -2.0 -3.4 FIG00956267: hypothetical protein compare
Pf1N1B4_4612 -1.9 -3.8 FIG00954117: hypothetical protein compare
Pf1N1B4_652 -1.8 -8.7 Sensory box histidine kinase compare
Pf1N1B4_27 -1.8 -5.4 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf1N1B4_1328 -1.8 -2.9 Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) compare
Pf1N1B4_3443 -1.8 -2.7 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf1N1B4_2958 -1.7 -3.1 Medium-chain-fatty-acid--CoA ligase (EC 6.2.1.-) compare
Pf1N1B4_4627 -1.7 -3.9 FIG00957600: hypothetical protein compare
Pf1N1B4_1057 -1.7 -3.2 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf1N1B4_1906 -1.7 -3.7 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) compare
Pf1N1B4_1566 -1.6 -5.7 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf1N1B4_1 -1.5 -2.0 Colicin V production protein compare
Pf1N1B4_257 -1.5 -5.6 sensor histidine kinase/response regulator compare
Pf1N1B4_2280 -1.5 -7.3 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf1N1B4_275 -1.4 -1.9 Organic hydroperoxide resistance transcriptional regulator compare
Pf1N1B4_578 -1.4 -2.4 enoyl-CoA hydratase, R-specific compare
Pf1N1B4_5187 -1.4 -2.0 5S RNA compare
Pf1N1B4_5275 -1.3 -2.0 hypothetical protein compare
Pf1N1B4_1317 -1.3 -2.7 Sensor histidine kinase/response regulator compare
Pf1N1B4_683 -1.3 -3.2 Fumarate hydratase class I, aerobic (EC 4.2.1.2) compare
Pf1N1B4_5284 -1.3 -1.8 hypothetical protein compare
Pf1N1B4_3081 -1.2 -10.6 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
Pf1N1B4_5370 -1.2 -1.4 hypothetical protein compare
Pf1N1B4_412 -1.2 -2.5 L-arabinose 1-dehydrogenase / D-galactose 1-dehydrogenase (EC 1.1.1.46; EC 1.1.1.48) (from data) compare
Pf1N1B4_3518 -1.2 -2.5 Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) compare
Pf1N1B4_232 -1.2 -2.4 DNA-binding response regulator, LuxR family compare
Pf1N1B4_4603 -1.1 -2.3 hypothetical protein compare
Pf1N1B4_5512 -1.1 -1.5 hypothetical protein compare
Pf1N1B4_1263 -1.1 -2.5 Cu(I)-responsive transcriptional regulator compare
Pf1N1B4_348 -1.1 -3.5 Cyclohexadienyl dehydrogenase (EC 1.3.1.12)(EC 1.3.1.43) / 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19) compare
Pf1N1B4_616 -1.1 -2.7 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf1N1B4_2857 -1.1 -2.7 Poly(A) polymerase (EC 2.7.7.19) compare
Pf1N1B4_3467 -1.1 -2.3 Flagellar biosynthesis protein FlgN compare
Pf1N1B4_5059 -1.1 -2.3 Transcriptional regulator, LysR family compare
Pf1N1B4_3985 -1.1 -2.1 Methylglutaconyl-CoA hydratase (EC 4.2.1.18) compare
Pf1N1B4_4824 -1.1 -2.2 Gamma-glutamyl-putrescine oxidase (EC1.4.3.-) compare
Pf1N1B4_4123 -1.1 -2.1 Isochorismate pyruvate-lyase (EC 4.-.-.-) compare
Pf1N1B4_4446 -1.1 -2.3 DNA topoisomerase III (EC 5.99.1.2) compare
Pf1N1B4_1845 -1.1 -2.0 FIG00954395: hypothetical protein compare
Pf1N1B4_3325 -1.1 -1.6 Sigma factor RpoE negative regulatory protein RseB precursor compare
Pf1N1B4_4857 -1.1 -3.6 Chemotaxis protein methyltransferase CheR (EC 2.1.1.80) compare
Pf1N1B4_3833 -1.0 -5.0 Major porin and structural outer membrane porin OprF compare
Pf1N1B4_1159 -1.0 -2.5 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
Pf1N1B4_5834 -1.0 -1.9 Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B (EC 2.8.3.5) compare
Pf1N1B4_3993 -1.0 -2.3 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
Pf1N1B4_1535 -1.0 -2.3 hypothetical protein compare
Pf1N1B4_4004 -1.0 -2.3 Peptidyl-prolyl cis-trans isomerase PpiB (EC 5.2.1.8) compare
Pf1N1B4_1819 -1.0 -2.9 NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2) compare
Pf1N1B4_5383 -1.0 -5.2 hypothetical protein compare
Pf1N1B4_2209 -0.9 -5.5 Exopolyphosphatase (EC 3.6.1.11) compare
Pf1N1B4_1126 -0.9 -2.1 Dipeptide transport ATP-binding protein DppD (TC 3.A.1.5.2) compare
Pf1N1B4_4359 -0.9 -2.7 PvcA protein, related to known isonitrile synthases compare
Pf1N1B4_4494 -0.9 -2.9 hypothetical protein compare
Pf1N1B4_1818 -0.9 -4.0 NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2) compare
Pf1N1B4_407 -0.9 -1.7 ADP-ribosylglycohydrolase YegU (EC 3.2.-.-) compare
Pf1N1B4_5371 -0.9 -1.6 hypothetical protein compare
Pf1N1B4_5552 -0.9 -1.9 hypothetical protein compare
Pf1N1B4_1590 -0.9 -3.9 Histidine utilization repressor compare
Pf1N1B4_189 -0.9 -2.7 Short-chain dehydrogenase, associated with 2-hydroxychromene-2-carboxylate isomerase family protein compare
Pf1N1B4_904 -0.9 -1.7 DNA-binding protein HU-beta compare
Pf1N1B4_1113 -0.9 -3.7 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf1N1B4_3906 -0.9 -2.0 DNA topoisomerase I (EC 5.99.1.2) compare
Pf1N1B4_3938 -0.9 -2.4 Integral membrane protein TerC compare
Pf1N1B4_1611 -0.9 -3.4 Nitrogen regulation protein NR(I) compare
Pf1N1B4_327 -0.9 -1.6 hypothetical protein compare
Pf1N1B4_4563 -0.9 -1.8 Sulfate transporter compare
Pf1N1B4_980 -0.9 -1.8 hypothetical protein compare
Pf1N1B4_716 -0.9 -2.5 Probable thiol oxidoreductase with 2 cytochrome c heme-binding sites compare
Pf1N1B4_4931 -0.9 -1.6 Glutarate-semialdehyde dehydrogenase (EC 1.2.1.20); Succinate-semialdehyde dehydrogenase [NADP+] (EC 1.2.1.79) compare
Pf1N1B4_3907 -0.9 -1.8 FIG00953287: hypothetical protein compare
Pf1N1B4_2225 -0.9 -5.8 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) compare
Pf1N1B4_1504 -0.8 -1.5 Acyl carrier protein compare
Pf1N1B4_4887 -0.8 -1.7 Pirin compare
Pf1N1B4_3849 -0.8 -2.7 Transcriptional regulator, GntR family compare
Pf1N1B4_4544 -0.8 -1.7 Uncharacterized protein ImpA compare
Pf1N1B4_4729 -0.8 -1.6 Hemolysin-type calcium-binding region compare
Pf1N1B4_3360 -0.8 -3.3 FIG00953701: hypothetical protein compare
Pf1N1B4_239 -0.8 -2.4 Similar to ribosomal large subunit pseudouridine synthase A compare
Pf1N1B4_967 -0.8 -1.4 hypothetical protein compare
Pf1N1B4_1118 -0.8 -1.8 Tryptophan synthase beta chain like (EC 4.2.1.20) compare
Pf1N1B4_539 -0.8 -1.4 Transcriptional regulators compare
Pf1N1B4_4273 -0.8 -3.0 Predicted transcriptional regulator of the myo-inositol catabolic operon compare
Pf1N1B4_1610 -0.8 -2.7 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
Pf1N1B4_1820 -0.8 -6.0 NAD(P) transhydrogenase subunit beta (EC 1.6.1.2) compare
Pf1N1B4_5659 -0.8 -5.3 NfuA Fe-S protein maturation compare
Pf1N1B4_5137 -0.8 -3.8 Carboxynorspermidine decarboxylase, putative (EC 4.1.1.-) compare
Pf1N1B4_4041 -0.8 -2.2 NADH ubiquinone oxidoreductase chain A (EC 1.6.5.3) compare
Pf1N1B4_3981 -0.8 -1.3 Predicted carboxypeptidase compare
Pf1N1B4_2683 -0.8 -2.9 LrgA-associated membrane protein LrgB compare
Pf1N1B4_1059 -0.8 -1.7 FIG137478: Hypothetical protein YbgI compare
Pf1N1B4_3143 -0.8 -1.6 RecA protein compare
Pf1N1B4_2860 -0.8 -3.7 FIG00954153: hypothetical protein compare
Pf1N1B4_4810 -0.8 -2.5 Polymyxin resistance protein PmrM compare
Pf1N1B4_1568 -0.8 -2.0 Twin-arginine translocation protein TatB compare
Pf1N1B4_1827 -0.8 -2.6 FIG00953482: hypothetical protein compare
Pf1N1B4_4276 -0.8 -3.1 5-deoxy-glucuronate isomerase (EC 5.3.1.-) compare
Pf1N1B4_3802 -0.8 -1.5 PlcB, ORFX, ORFP, ORFB, ORFA, ldh gene compare
Pf1N1B4_3799 -0.8 -2.2 1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51) compare
Pf1N1B4_3153 -0.8 -1.5 hypothetical protein compare
Pf1N1B4_602 -0.8 -1.9 NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) compare
Pf1N1B4_4485 -0.8 -1.1 membrane protein, putative compare
Pf1N1B4_4035 -0.7 -1.5 NADH-ubiquinone oxidoreductase chain G (EC 1.6.5.3) compare
Pf1N1B4_814 -0.7 -1.7 Transcriptional regulator, PadR family compare
Pf1N1B4_4326 -0.7 -1.5 N-carbamoylputrescine amidase (3.5.1.53) compare
Pf1N1B4_5576 -0.7 -1.5 hypothetical protein compare
Pf1N1B4_1375 -0.7 -5.0 Mannose-6-phosphate isomerase (EC 5.3.1.8) compare
Pf1N1B4_1679 -0.7 -1.2 Membrane-fusion protein compare
Pf1N1B4_3494 -0.7 -1.9 Flavoprotein WrbA compare
Pf1N1B4_5416 -0.7 -2.4 hypothetical protein compare
Pf1N1B4_5302 -0.7 -1.7 hypothetical protein compare
Pf1N1B4_197 -0.7 -1.6 FIG139991: Putative thiamine pyrophosphate-requiring enzyme compare
Pf1N1B4_2695 -0.7 -1.6 Rare lipoprotein A precursor compare
Pf1N1B4_2682 -0.7 -1.4 Antiholin-like protein LrgA compare
Pf1N1B4_4646 -0.7 -2.4 Transcriptional regulator, GntR family domain / Aspartate aminotransferase (EC 2.6.1.1) compare
Pf1N1B4_3259 -0.7 -2.5 FIG00956006: hypothetical protein compare
Pf1N1B4_2733 -0.7 -1.4 DNA polymerase III alpha subunit (EC 2.7.7.7) compare
Pf1N1B4_2959 -0.7 -2.8 FIG067310: hypothetical protein compare
Pf1N1B4_2441 -0.7 -2.3 Electron transfer flavoprotein, alpha subunit compare
Pf1N1B4_3918 -0.7 -1.7 Thiamin biosynthesis lipoprotein ApbE compare
Pf1N1B4_5051 -0.7 -1.9 Sensor protein DegS compare
Pf1N1B4_5906 -0.7 -1.8 Esterase/lipase compare
Pf1N1B4_1936 -0.7 -2.9 Chromosome (plasmid) partitioning protein ParA compare
Pf1N1B4_669 -0.7 -2.2 INTEGRAL MEMBRANE PROTEIN (Rhomboid family) compare
Pf1N1B4_4640 -0.7 -2.3 MoxR-like ATPase in aerotolerance operon compare
Pf1N1B4_4145 -0.7 -1.5 hypothetical protein compare
Pf1N1B4_3524 -0.7 -1.9 FIG00955363: hypothetical protein compare
Pf1N1B4_4765 -0.7 -1.6 2-ketogluconate kinase (EC 2.7.1.13) compare
Pf1N1B4_1668 -0.7 -2.5 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
Pf1N1B4_4200 -0.7 -2.5 PhaK-like protein compare
Pf1N1B4_3241 -0.7 -1.5 hypothetical protein compare
Pf1N1B4_3328 -0.7 -1.4 Rhodanese-like domain protein compare
Pf1N1B4_5737 -0.7 -1.8 Nitrate/nitrite transporter compare
Pf1N1B4_1239 -0.7 -3.8 Omega-amino acid--pyruvate aminotransferase (EC 2.6.1.18) compare
Pf1N1B4_4797 -0.7 -1.9 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf1N1B4_3451 -0.7 -2.0 Aspartokinase (EC 2.7.2.4) compare
Pf1N1B4_662 -0.7 -2.1 FIG00955875: hypothetical protein compare
Pf1N1B4_2674 -0.7 -1.1 hypothetical protein compare
Pf1N1B4_1721 -0.7 -1.6 DNA-binding heavy metal response regulator compare
Pf1N1B4_2706 -0.7 -1.5 FIG00954871: hypothetical protein compare
Pf1N1B4_5386 -0.7 -1.3 hypothetical protein compare
Pf1N1B4_3939 -0.7 -2.1 FIG00953489: hypothetical protein compare
Pf1N1B4_273 -0.7 -2.3 putative membrane protein compare
Pf1N1B4_2949 -0.7 -1.5 FIG00956396: hypothetical protein compare
Pf1N1B4_5571 -0.7 -2.1 hypothetical protein compare
Pf1N1B4_1238 -0.7 -4.5 Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) compare
Pf1N1B4_3445 -0.7 -1.9 Succinylarginine dihydrolase (EC 3.5.3.23) compare
Pf1N1B4_2094 -0.7 -2.2 Outer membrane protein ImpK/VasF, OmpA/MotB domain compare
Pf1N1B4_6046 -0.7 -3.5 hypothetical protein compare
Pf1N1B4_886 -0.7 -1.4 FIG137478: Hypothetical protein compare
Pf1N1B4_5957 -0.7 -1.6 Arsenical resistance operon repressor compare
Pf1N1B4_4139 -0.7 -1.4 Transcriptional regulator, MerR family compare
Pf1N1B4_4569 -0.7 -1.4 DNA-3-methyladenine glycosylase II (EC 3.2.2.21) compare
Pf1N1B4_644 -0.7 -1.2 Cold shock protein CspC compare


Specific Phenotypes

For 2 genes in this experiment

For carbon source a-Ketoglutaric acid disodium salt hydrate in Pseudomonas fluorescens FW300-N1B4

For carbon source a-Ketoglutaric acid disodium salt hydrate across organisms